IL177268A0 - Site -specific chemical modification of hiv gp41-derived peptides - Google Patents

Site -specific chemical modification of hiv gp41-derived peptides

Info

Publication number
IL177268A0
IL177268A0 IL177268A IL17726806A IL177268A0 IL 177268 A0 IL177268 A0 IL 177268A0 IL 177268 A IL177268 A IL 177268A IL 17726806 A IL17726806 A IL 17726806A IL 177268 A0 IL177268 A0 IL 177268A0
Authority
IL
Israel
Prior art keywords
hiv
site
chemical modification
specific chemical
derived peptides
Prior art date
Application number
IL177268A
Other languages
English (en)
Original Assignee
Trimeris Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Trimeris Inc filed Critical Trimeris Inc
Publication of IL177268A0 publication Critical patent/IL177268A0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • AIDS & HIV (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IL177268A 2004-03-15 2006-08-03 Site -specific chemical modification of hiv gp41-derived peptides IL177268A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55306304P 2004-03-15 2004-03-15
PCT/US2005/007486 WO2005089796A1 (fr) 2004-03-15 2005-03-08 Modification chimique specifique de site de peptides derives de gp41 du vih

Publications (1)

Publication Number Publication Date
IL177268A0 true IL177268A0 (en) 2006-12-10

Family

ID=34993445

Family Applications (1)

Application Number Title Priority Date Filing Date
IL177268A IL177268A0 (en) 2004-03-15 2006-08-03 Site -specific chemical modification of hiv gp41-derived peptides

Country Status (6)

Country Link
EP (1) EP1734994A1 (fr)
JP (1) JP2007529522A (fr)
CN (1) CN1929860A (fr)
CA (1) CA2556032A1 (fr)
IL (1) IL177268A0 (fr)
WO (1) WO2005089796A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2558583C (fr) * 2004-03-15 2013-07-09 Nektar Therapeutics Al, Corporation Compositions a base de polymeres et conjugues d'inhibiteurs d'entree du vih
CA2626675A1 (fr) * 2005-11-02 2007-05-18 Ambrx, Inc. Inhibiteurs de fusions polypeptidiques biosynthetiques
CN1793170A (zh) * 2005-12-14 2006-06-28 中国人民解放军军事医学科学院生物工程研究所 抑制hiv病毒融合的多肽及其用途
CA2651793C (fr) * 2006-02-02 2015-07-07 Trimeris, Inc. Peptides inhibiteurs de fusion du vih a proprietes biologiques ameliorees
KR20100016142A (ko) * 2007-04-03 2010-02-12 트라이머리스, 인코퍼레이티드 항바이러스 펩티드 치료제 전달용 신규 제제
WO2011095989A2 (fr) * 2010-02-04 2011-08-11 Matrix Laboratories Ltd Procédé amélioré pour préparer de l'enfuvirtide
JP2013522352A (ja) * 2010-03-24 2013-06-13 メディカル リサーチ カウンシル 方法
EA024755B1 (ru) * 2010-05-21 2016-10-31 ИксЭль-ПРОТЕИН ГМБХ Биосинтетические нерегулярные спиральные полипептиды пролина/аланина и их применения
CN104788548B (zh) * 2014-01-20 2018-06-05 中国人民解放军军事医学科学院毒物药物研究所 新型抗hiv感染多肽及其利用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6271198B1 (en) * 1996-11-06 2001-08-07 Genentech, Inc. Constrained helical peptides and methods of making same

Also Published As

Publication number Publication date
CA2556032A1 (fr) 2005-09-29
WO2005089796A1 (fr) 2005-09-29
JP2007529522A (ja) 2007-10-25
CN1929860A (zh) 2007-03-14
EP1734994A1 (fr) 2006-12-27

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