IL177239A - המצאה של סמן ביולוגי המבוסס על נוגדן חי–שבטי ותשתית התפתחות - Google Patents
המצאה של סמן ביולוגי המבוסס על נוגדן חי–שבטי ותשתית התפתחותInfo
- Publication number
- IL177239A IL177239A IL177239A IL17723906A IL177239A IL 177239 A IL177239 A IL 177239A IL 177239 A IL177239 A IL 177239A IL 17723906 A IL17723906 A IL 17723906A IL 177239 A IL177239 A IL 177239A
- Authority
- IL
- Israel
- Prior art keywords
- complex analyte
- analyte
- complex
- monoclonal antibodies
- antigen
- Prior art date
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Classifications
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- G—PHYSICS
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- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- G—PHYSICS
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54386—Analytical elements
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies; monoclonal antibodies per se are classified with their corresponding antigens
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
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- Immunology (AREA)
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- Pathology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54300404P | 2004-02-09 | 2004-02-09 | |
| PCT/US2005/004484 WO2005077106A2 (en) | 2004-02-09 | 2005-02-09 | Monoclonal antibody based biomarker discovery and development platform |
Publications (2)
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| IL177239A0 IL177239A0 (en) | 2008-03-20 |
| IL177239A true IL177239A (he) | 2011-07-31 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| IL177239A IL177239A (he) | 2004-02-09 | 2006-08-02 | המצאה של סמן ביולוגי המבוסס על נוגדן חי–שבטי ותשתית התפתחות |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8512959B2 (he) |
| EP (1) | EP1714152A4 (he) |
| AU (1) | AU2005211790B2 (he) |
| CA (1) | CA2555699C (he) |
| IL (1) | IL177239A (he) |
| WO (1) | WO2005077106A2 (he) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070293437A1 (en) * | 2004-10-23 | 2007-12-20 | Andras Guttman | Expression Profiling Platform Technology |
| CA2616552A1 (en) * | 2005-07-28 | 2007-02-01 | Biosystems International Sas | Normalization of complex analyte mixtures |
| WO2007035633A2 (en) | 2005-09-16 | 2007-03-29 | President & Fellows Of Harvard College | Screening assays and methods |
| US20100062461A1 (en) * | 2006-07-11 | 2010-03-11 | Leap Biosciences Corporation | Multiplex detection of cell surface receptors or immobilized antigens |
| ATE532074T1 (de) * | 2007-05-04 | 2011-11-15 | Biosystems Internat Sas | Auf multi-immunoaffinität basierende indentifizierung von antigenen |
| EP2572203B1 (en) * | 2010-05-17 | 2017-10-25 | The Board of Regents of The University of Texas System | Determination of antigen-specific antibody sequences in blood circulation |
| CN108220297A (zh) | 2011-03-09 | 2018-06-29 | 细胞信号科技公司 | 用于生成单克隆抗体的方法和试剂 |
| WO2013078455A2 (en) | 2011-11-23 | 2013-05-30 | The Board Of Regents Of The University Of Texas System | Proteomic identification of antibodies |
| JP6558830B2 (ja) | 2012-06-15 | 2019-08-14 | ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム | 複数転写産物のハイスループットシークエンシング |
| US10513733B2 (en) | 2015-03-23 | 2019-12-24 | Board Of Regents, The University Of Texas System | High throughout sequencing of paired VH and VL transcripts from B cells secreting antigen-specific antibodies |
| WO2017205694A1 (en) * | 2016-05-25 | 2017-11-30 | University Of Maryland, Baltimore | Methods of making active antibodies from biological fluids |
| WO2018237357A1 (en) | 2017-06-22 | 2018-12-27 | University Of Maryland, Baltimore | HIV-LARGE SPECTRUM HIV NEUTRALIZATION ANTIBODIES AGAINST HIV |
| WO2019084538A1 (en) | 2017-10-27 | 2019-05-02 | Board Of Regents, The University Of Texas System | TUMOR SPECIFIC ANTIBODIES, T CELL RECEPTORS AND METHODS OF IDENTIFICATION THEREOF |
| EP3671210A1 (en) | 2018-12-21 | 2020-06-24 | Biosystems International KFT | Lung cancer protein epitomic biomarkers |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5242799A (en) * | 1989-11-02 | 1993-09-07 | Biomira, Inc. | Lectin-antibody immunoassays for TF epitope-bearing antigens |
| US5652138A (en) * | 1992-09-30 | 1997-07-29 | The Scripps Research Institute | Human neutralizing monoclonal antibodies to human immunodeficiency virus |
| US6074827A (en) * | 1996-07-30 | 2000-06-13 | Aclara Biosciences, Inc. | Microfluidic method for nucleic acid purification and processing |
| WO1998021334A2 (en) * | 1996-11-13 | 1998-05-22 | Morphogenesis, Inc. | Antibody mg1 recognizing a small subset of human hematopoietic cells |
| AU6261998A (en) * | 1998-02-02 | 1999-08-16 | Novadx | Removal of abundant interfering proteins from a liquid sample using a collapsible affinity matrix |
| US20030007991A1 (en) * | 1998-09-25 | 2003-01-09 | Masters David B. | Devices including protein matrix materials and methods of making and using thereof |
| US7396905B1 (en) * | 1999-05-21 | 2008-07-08 | Mckeon Frank | Calcipressins: endogenous inhibitors of calcineurin, uses and reagents related thereto |
| WO2003024389A2 (en) * | 2001-07-30 | 2003-03-27 | Immunex Corporation | T. reesei phytase enyzmes, polynucleides encoding the enzymes, vectors and host cells thereof, and methods of using |
| AU2002326710A1 (en) * | 2001-08-22 | 2003-04-14 | Steven Kessler | Methods for screening monoclonal antibodies on heterogeneous antigen substrates |
| US20030044849A1 (en) * | 2001-08-22 | 2003-03-06 | Steven Kessler | Methods for screening monoclonal antibodies on heterogeneous antigen substrates |
| US8071322B2 (en) * | 2002-11-12 | 2011-12-06 | Epitomics, Inc. | Method for identifying differentially expressed proteins |
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2005
- 2005-02-09 AU AU2005211790A patent/AU2005211790B2/en not_active Ceased
- 2005-02-09 US US10/588,392 patent/US8512959B2/en not_active Expired - Fee Related
- 2005-02-09 WO PCT/US2005/004484 patent/WO2005077106A2/en not_active Ceased
- 2005-02-09 EP EP05713426A patent/EP1714152A4/en not_active Withdrawn
- 2005-02-09 CA CA2555699A patent/CA2555699C/en not_active Expired - Fee Related
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2006
- 2006-08-02 IL IL177239A patent/IL177239A/he not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2555699C (en) | 2013-10-15 |
| IL177239A0 (en) | 2008-03-20 |
| AU2005211790B2 (en) | 2010-03-11 |
| US8512959B2 (en) | 2013-08-20 |
| AU2005211790A2 (en) | 2005-08-25 |
| CA2555699A1 (en) | 2005-08-25 |
| EP1714152A2 (en) | 2006-10-25 |
| US20070172887A1 (en) | 2007-07-26 |
| WO2005077106A2 (en) | 2005-08-25 |
| AU2005211790A1 (en) | 2005-08-25 |
| EP1714152A4 (en) | 2008-08-13 |
| WO2005077106A3 (en) | 2006-02-02 |
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