IL165042A0 - Adduct of topiramate and tramadol hydrochloride and uses thereof - Google Patents
Adduct of topiramate and tramadol hydrochloride and uses thereofInfo
- Publication number
- IL165042A0 IL165042A0 IL16504203A IL16504203A IL165042A0 IL 165042 A0 IL165042 A0 IL 165042A0 IL 16504203 A IL16504203 A IL 16504203A IL 16504203 A IL16504203 A IL 16504203A IL 165042 A0 IL165042 A0 IL 165042A0
- Authority
- IL
- Israel
- Prior art keywords
- topiramate
- adduct
- tramadol hydrochloride
- tramadol
- hydrochloride
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/74—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
- C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
- C07H9/04—Cyclic acetals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP02077019A EP1364649A1 (en) | 2002-05-23 | 2002-05-23 | Adduct of topiramate and tramadol hydrochioride and uses thereof |
PCT/EP2003/005321 WO2003099273A1 (en) | 2002-05-23 | 2003-05-16 | Adduct of topiramate and tramadol hydrochloride and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
IL165042A0 true IL165042A0 (en) | 2005-12-18 |
Family
ID=29286193
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL16504203A IL165042A0 (en) | 2002-05-23 | 2003-05-16 | Adduct of topiramate and tramadol hydrochloride and uses thereof |
Country Status (13)
Country | Link |
---|---|
US (1) | US7378519B2 (ru) |
EP (2) | EP1364649A1 (ru) |
JP (1) | JP2005530808A (ru) |
CN (1) | CN1278681C (ru) |
AU (1) | AU2003242552A1 (ru) |
BR (1) | BR0311193A (ru) |
CA (1) | CA2486709A1 (ru) |
IL (1) | IL165042A0 (ru) |
MX (1) | MXPA04011573A (ru) |
PL (1) | PL373430A1 (ru) |
RU (1) | RU2004137681A (ru) |
WO (1) | WO2003099273A1 (ru) |
ZA (1) | ZA200410335B (ru) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6375957B1 (en) | 1997-12-22 | 2002-04-23 | Euro-Celtique, S.A. | Opioid agonist/opioid antagonist/acetaminophen combinations |
SI1685839T1 (sl) | 1997-12-22 | 2013-08-30 | Euro-Celtique S.A. | Farmacevtska oralna dozirna oblika, ki vsebuje kombinacijo opioidnega agonista in opioidnega antagonista |
CN1525851A (zh) | 2001-05-11 | 2004-09-01 | ������ҩ������˾ | 抗滥用阿片样物质控释剂型 |
US7790905B2 (en) | 2002-02-15 | 2010-09-07 | Mcneil-Ppc, Inc. | Pharmaceutical propylene glycol solvate compositions |
US7927613B2 (en) | 2002-02-15 | 2011-04-19 | University Of South Florida | Pharmaceutical co-crystal compositions |
CA2477923C (en) | 2002-03-01 | 2021-02-23 | University Of South Florida | Multiple-component solid phases containing at least one active pharmaceutical ingredient |
KR20040098050A (ko) | 2002-04-05 | 2004-11-18 | 유로-셀띠끄 소시에떼 아노님 | 옥시코돈 및 날록손을 포함하는 약제학적 제제 |
MXPA05000232A (es) | 2002-06-21 | 2005-06-17 | Transform Pharmaceuticals Inc | Composiciones farmaceuticas con disolucion mejorada. |
MXPA05006210A (es) * | 2002-12-13 | 2005-08-19 | Cilag Ag | Preparaciones de liberacion controlada que comprenden tramadol y topiramato. |
US8183290B2 (en) | 2002-12-30 | 2012-05-22 | Mcneil-Ppc, Inc. | Pharmaceutically acceptable propylene glycol solvate of naproxen |
EP1604667A1 (en) * | 2004-06-08 | 2005-12-14 | Euro-Celtique S.A. | Opioids for the treatment of the restless leg syndrome |
EP1604666A1 (en) | 2004-06-08 | 2005-12-14 | Euro-Celtique S.A. | Opioids for the treatment of the Chronic Obstructive Pulmonary Disease (COPD) |
EP1702558A1 (en) | 2005-02-28 | 2006-09-20 | Euro-Celtique S.A. | Method and device for the assessment of bowel function |
EP2405915B1 (en) | 2009-03-10 | 2018-10-24 | Euro-Celtique S.A. | Immediate release pharmaceutical compositions comprising oxycodone and naloxone |
US8652527B1 (en) | 2013-03-13 | 2014-02-18 | Upsher-Smith Laboratories, Inc | Extended-release topiramate capsules |
US9101545B2 (en) | 2013-03-15 | 2015-08-11 | Upsher-Smith Laboratories, Inc. | Extended-release topiramate capsules |
NZ716267A (en) | 2013-07-23 | 2017-05-26 | Euro Celtique Sa | A combination of oxycodone and naloxone for use in treating pain in patients suffering from pain and a disease resulting in intestinal dysbiosis and/or increasing the risk for intestinal bacterial translocation |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3652589A (en) * | 1967-07-27 | 1972-03-28 | Gruenenthal Chemie | 1-(m-substituted phenyl)-2-aminomethyl cyclohexanols |
US4513006A (en) * | 1983-09-26 | 1985-04-23 | Mcneil Lab., Inc. | Anticonvulsant sulfamate derivatives |
AU657351B2 (en) * | 1991-09-06 | 1995-03-09 | Mcneilab, Inc. | Compositions comprising a tramadol material and any of codeine, oxycodone or hydrocodone and their use |
KR100243956B1 (ko) * | 1991-09-06 | 2000-03-02 | 랄프 알. 팔로 | 트라마돌 물질 및 아세트아미노펜을 포함하는 통증 치료용 약제학적 조성물 |
US5516803A (en) * | 1991-10-30 | 1996-05-14 | Mcneilab, Inc. | Composition comprising a tramadol material and a non-steroidal anti-inflammatory drug |
DE19927689A1 (de) * | 1999-06-17 | 2000-12-21 | Gruenenthal Gmbh | Orale Darreichungsformen zur Verabreichung einer fixen Kombination von Tramadol und Diclofenac |
WO2001013904A2 (en) * | 1999-08-20 | 2001-03-01 | Ortho-Mcneil Pharmaceutical, Inc. | Composition comprising a tramadol material and an anticonvulsant drug |
DE19940740A1 (de) * | 1999-08-31 | 2001-03-01 | Gruenenthal Gmbh | Pharmazeutische Salze |
-
2002
- 2002-05-23 EP EP02077019A patent/EP1364649A1/en not_active Withdrawn
-
2003
- 2003-05-16 JP JP2004506797A patent/JP2005530808A/ja active Pending
- 2003-05-16 CN CNB038110695A patent/CN1278681C/zh not_active Expired - Fee Related
- 2003-05-16 IL IL16504203A patent/IL165042A0/xx unknown
- 2003-05-16 BR BR0311193-8A patent/BR0311193A/pt not_active IP Right Cessation
- 2003-05-16 WO PCT/EP2003/005321 patent/WO2003099273A1/en not_active Application Discontinuation
- 2003-05-16 CA CA002486709A patent/CA2486709A1/en not_active Abandoned
- 2003-05-16 US US10/514,739 patent/US7378519B2/en not_active Expired - Lifetime
- 2003-05-16 EP EP03755109A patent/EP1509222A1/en not_active Withdrawn
- 2003-05-16 AU AU2003242552A patent/AU2003242552A1/en not_active Abandoned
- 2003-05-16 PL PL03373430A patent/PL373430A1/xx not_active Application Discontinuation
- 2003-05-16 RU RU2004137681/15A patent/RU2004137681A/ru not_active Application Discontinuation
- 2003-05-16 MX MXPA04011573A patent/MXPA04011573A/es not_active Application Discontinuation
-
2004
- 2004-12-22 ZA ZA200410335A patent/ZA200410335B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
EP1364649A1 (en) | 2003-11-26 |
AU2003242552A1 (en) | 2003-12-12 |
EP1509222A1 (en) | 2005-03-02 |
JP2005530808A (ja) | 2005-10-13 |
US20060234949A1 (en) | 2006-10-19 |
WO2003099273A1 (en) | 2003-12-04 |
CN1278681C (zh) | 2006-10-11 |
CN1652767A (zh) | 2005-08-10 |
BR0311193A (pt) | 2005-02-22 |
RU2004137681A (ru) | 2005-06-10 |
MXPA04011573A (es) | 2005-03-07 |
US7378519B2 (en) | 2008-05-27 |
CA2486709A1 (en) | 2003-12-04 |
PL373430A1 (en) | 2005-08-22 |
ZA200410335B (en) | 2006-02-22 |
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