IL162136A0 - Nucleotide analogues and their use for nucleic acid sequencing - Google Patents
Nucleotide analogues and their use for nucleic acid sequencingInfo
- Publication number
- IL162136A0 IL162136A0 IL16213602A IL16213602A IL162136A0 IL 162136 A0 IL162136 A0 IL 162136A0 IL 16213602 A IL16213602 A IL 16213602A IL 16213602 A IL16213602 A IL 16213602A IL 162136 A0 IL162136 A0 IL 162136A0
- Authority
- IL
- Israel
- Prior art keywords
- nucleic acid
- acid sequencing
- nucleotide analogues
- analogues
- nucleotide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B11/00—Diaryl- or thriarylmethane dyes
- C09B11/04—Diaryl- or thriarylmethane dyes derived from triarylmethanes, i.e. central C-atom is substituted by amino, cyano, alkyl
- C09B11/06—Hydroxy derivatives of triarylmethanes in which at least one OH group is bound to an aryl nucleus and their ethers or esters
- C09B11/08—Phthaleins; Phenolphthaleins; Fluorescein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0128526.1A GB0128526D0 (en) | 2001-11-29 | 2001-11-29 | Nucleotide analogues |
PCT/GB2002/005375 WO2003048178A2 (en) | 2001-11-29 | 2002-11-28 | Nucleotide analogues and their use for nucleic acid sequencing |
Publications (1)
Publication Number | Publication Date |
---|---|
IL162136A0 true IL162136A0 (en) | 2005-11-20 |
Family
ID=9926632
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL16213602A IL162136A0 (en) | 2001-11-29 | 2002-11-28 | Nucleotide analogues and their use for nucleic acid sequencing |
Country Status (8)
Country | Link |
---|---|
US (1) | US20050164182A1 (xx) |
EP (1) | EP1451201A2 (xx) |
JP (1) | JP2005517646A (xx) |
AU (1) | AU2002356270A1 (xx) |
CA (1) | CA2468432A1 (xx) |
GB (1) | GB0128526D0 (xx) |
IL (1) | IL162136A0 (xx) |
WO (1) | WO2003048178A2 (xx) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6780591B2 (en) | 1998-05-01 | 2004-08-24 | Arizona Board Of Regents | Method of determining the nucleotide sequence of oligonucleotides and DNA molecules |
US7875440B2 (en) | 1998-05-01 | 2011-01-25 | Arizona Board Of Regents | Method of determining the nucleotide sequence of oligonucleotides and DNA molecules |
US9708358B2 (en) | 2000-10-06 | 2017-07-18 | The Trustees Of Columbia University In The City Of New York | Massive parallel method for decoding DNA and RNA |
DE60127162T2 (de) | 2000-10-06 | 2008-04-24 | The Trustees Of Columbia University In The City Of New York | Massives Parallelverfahren zur Dekodierung von DNA und RNA |
GB0129012D0 (en) | 2001-12-04 | 2002-01-23 | Solexa Ltd | Labelled nucleotides |
US11008359B2 (en) | 2002-08-23 | 2021-05-18 | Illumina Cambridge Limited | Labelled nucleotides |
US7414116B2 (en) | 2002-08-23 | 2008-08-19 | Illumina Cambridge Limited | Labelled nucleotides |
EP2607369B1 (en) | 2002-08-23 | 2015-09-23 | Illumina Cambridge Limited | Modified nucleotides for polynucleotide sequencing |
EP1725572B1 (de) | 2003-11-05 | 2017-05-31 | AGCT GmbH | Makromolekulare nukleotidverbindungen und methoden zu deren anwendung |
US7169560B2 (en) | 2003-11-12 | 2007-01-30 | Helicos Biosciences Corporation | Short cycle methods for sequencing polynucleotides |
DE602005020421D1 (de) | 2004-02-19 | 2010-05-20 | Helicos Biosciences Corp | Verfahren zur analyse von polynukleotidsequenzen |
US9035035B2 (en) | 2004-11-05 | 2015-05-19 | Genovoxx Gmbh | Macromolecular nucleotide compounds and methods for using the same |
US7666593B2 (en) | 2005-08-26 | 2010-02-23 | Helicos Biosciences Corporation | Single molecule sequencing of captured nucleic acids |
US20100304368A1 (en) * | 2006-09-20 | 2010-12-02 | Dmitry Cherkasov | Components and method for enzymatic synthesis of nucleic acids |
WO2008042067A2 (en) | 2006-09-28 | 2008-04-10 | Illumina, Inc. | Compositions and methods for nucleotide sequencing |
GB2457402B (en) | 2006-12-01 | 2011-10-19 | Univ Columbia | Four-color DNA sequencing by synthesis using cleavable fluorescent nucleotide reversible terminators |
BRPI0719923B1 (pt) * | 2006-12-05 | 2021-08-17 | Agilent Technologies Inc | Métodos para sequenciamento de um ácido nucléico alvo, para conversão de um componente de ocorrência não natural em uma molécula de ácido nucléico em um componente de ocorrência natural, para terminar uma síntese de ácido nucléico, e para realizar o sequenciamento de sanger ou tipo sanger, e compostos |
CN101631796B (zh) * | 2007-03-09 | 2013-08-07 | 独立行政法人理化学研究所 | 具有由单核苷或单核苷酸衍生的结构的化合物、核酸、标记物以及核酸检测方法和试剂盒 |
US9163053B2 (en) * | 2007-05-18 | 2015-10-20 | Fluidigm Corporation | Nucleotide analogs |
US7678894B2 (en) * | 2007-05-18 | 2010-03-16 | Helicos Biosciences Corporation | Nucleotide analogs |
EP2725107B1 (en) | 2007-10-19 | 2018-08-29 | The Trustees of Columbia University in the City of New York | DNA sequencing with non-fluorescent nucleotide reversible terminators and cleavable label modified ddNTPs and nucleic acid comprising inosine with reversible terminators |
EP2207900B1 (en) | 2007-10-19 | 2015-04-29 | The Trustees of Columbia University in the City of New York | Design and synthesis of cleavable fluorescent nucleotides as reversible terminators for dna sequencing by synthesis |
EP2307565B1 (en) | 2008-06-11 | 2017-11-29 | Lasergen, Inc. | Reversible nucleosides and nucleotides terminators and their use in dna sequencing |
EP2488492B1 (en) * | 2009-10-14 | 2016-01-13 | Dana-Farber Cancer Institute, Inc. | Protected amine labels and use in detecting analytes |
JP6333297B2 (ja) | 2013-03-15 | 2018-05-30 | イルミナ ケンブリッジ リミテッド | 修飾ヌクレオシドまたは修飾ヌクレオチド |
US10648026B2 (en) | 2013-03-15 | 2020-05-12 | The Trustees Of Columbia University In The City Of New York | Raman cluster tagged molecules for biological imaging |
EP3837380A4 (en) | 2018-08-17 | 2022-05-11 | Cellecta, Inc. | MULTIPLEX PREPARATION OF BARCODE GENE-SPECIFIC DNA FRAGMENTS |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE113059T1 (de) * | 1987-06-24 | 1994-11-15 | Florey Howard Inst | Nukleosid-derivate. |
US5998603A (en) * | 1994-09-29 | 1999-12-07 | Isis Pharmaceuticals, Inc. | 4'-desmethyl nucleoside analogs, and oligomers thereof |
FR2703052B1 (fr) * | 1993-03-26 | 1995-06-02 | Pasteur Institut | Nouvelle méthode de séquençage d'acides nucléiques. |
US6482655B1 (en) * | 1993-07-23 | 2002-11-19 | University Of Utah Research Foundation | Immunoassay procedure utilizing fluorogenic tracer antigens |
CA2225531A1 (en) * | 1995-06-23 | 1997-01-09 | Baylor College Of Medicine | Alternative dye-labeled primers, ribonucleotides, deoxyribonucleotides, and dideoxyribonucleotides for automated dna analysis and homogeneous amplification/detection assays |
US6287821B1 (en) * | 1998-06-11 | 2001-09-11 | Orchid Biosciences, Inc. | Nucleotide analogues with 3'-pro-fluorescent fluorophores in nucleic acid sequence analysis |
US6322980B1 (en) * | 1999-04-30 | 2001-11-27 | Aclara Biosciences, Inc. | Single nucleotide detection using degradation of a fluorescent sequence |
DE19952160A1 (de) * | 1999-10-29 | 2001-05-03 | Markus Sauer | Verfahren, Vorrichtung und farbstoffmarkiertes Peptid zum Nachweis eines Moleküls, sowie Verfahren zur Herstellung eines farbstoffmarkierten Peptids und dessen Verwendung |
GB0013276D0 (en) * | 2000-06-01 | 2000-07-26 | Amersham Pharm Biotech Uk Ltd | Nucleotide analogues |
CA2412567A1 (en) * | 2000-06-07 | 2001-12-13 | Li-Cor, Inc. | Charge-switch nucleotides |
-
2001
- 2001-11-29 GB GBGB0128526.1A patent/GB0128526D0/en not_active Ceased
-
2002
- 2002-11-28 EP EP02804269A patent/EP1451201A2/en not_active Withdrawn
- 2002-11-28 IL IL16213602A patent/IL162136A0/xx unknown
- 2002-11-28 JP JP2003549366A patent/JP2005517646A/ja not_active Withdrawn
- 2002-11-28 WO PCT/GB2002/005375 patent/WO2003048178A2/en not_active Application Discontinuation
- 2002-11-28 CA CA002468432A patent/CA2468432A1/en not_active Abandoned
- 2002-11-28 AU AU2002356270A patent/AU2002356270A1/en not_active Abandoned
- 2002-11-28 US US10/496,761 patent/US20050164182A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU2002356270A1 (en) | 2003-06-17 |
WO2003048178A2 (en) | 2003-06-12 |
US20050164182A1 (en) | 2005-07-28 |
JP2005517646A (ja) | 2005-06-16 |
WO2003048178A3 (en) | 2003-11-27 |
GB0128526D0 (en) | 2002-01-23 |
EP1451201A2 (en) | 2004-09-01 |
CA2468432A1 (en) | 2003-06-12 |
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