IL161790A0 - Deuterated pyrazolopyrimidinones and drugs containing said compounds - Google Patents
Deuterated pyrazolopyrimidinones and drugs containing said compoundsInfo
- Publication number
- IL161790A0 IL161790A0 IL16179002A IL16179002A IL161790A0 IL 161790 A0 IL161790 A0 IL 161790A0 IL 16179002 A IL16179002 A IL 16179002A IL 16179002 A IL16179002 A IL 16179002A IL 161790 A0 IL161790 A0 IL 161790A0
- Authority
- IL
- Israel
- Prior art keywords
- compounds
- drugs containing
- deuterated pyrazolopyrimidinones
- pyrazolopyrimidinones
- deuterated
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- DOTPSQVYOBAWPQ-UHFFFAOYSA-N pyrazolo[4,3-d]pyrimidin-3-one Chemical class N1=CN=C2C(=O)N=NC2=C1 DOTPSQVYOBAWPQ-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10155018A DE10155018A1 (de) | 2001-11-07 | 2001-11-07 | Deuterierte Pyrazolopyrimidinone sowie diese Verbindungen enthaltende Arzneimittel |
| PCT/DE2002/004216 WO2003039439A2 (de) | 2001-11-07 | 2002-11-07 | Deuterierte pyrazolopyrimidinone sowie diese verbindungen enthaltende arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL161790A0 true IL161790A0 (en) | 2005-11-20 |
Family
ID=7705148
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL16179002A IL161790A0 (en) | 2001-11-07 | 2002-11-07 | Deuterated pyrazolopyrimidinones and drugs containing said compounds |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20050069276A1 (cs) |
| EP (1) | EP1444234A2 (cs) |
| JP (1) | JP2005509646A (cs) |
| KR (1) | KR20050044381A (cs) |
| CN (1) | CN1606557A (cs) |
| CA (1) | CA2470271A1 (cs) |
| CZ (1) | CZ2004639A3 (cs) |
| DE (1) | DE10155018A1 (cs) |
| HU (1) | HUP0401721A3 (cs) |
| IL (1) | IL161790A0 (cs) |
| IS (1) | IS7246A (cs) |
| NO (1) | NO20042337L (cs) |
| NZ (1) | NZ533385A (cs) |
| PL (1) | PL369654A1 (cs) |
| RU (1) | RU2004117157A (cs) |
| WO (1) | WO2003039439A2 (cs) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090291958A1 (en) * | 2006-06-08 | 2009-11-26 | Auspex Pharmaceuticals, Inc. | Substituted PDE5 inhibitors |
| US20080194529A1 (en) * | 2007-02-12 | 2008-08-14 | Auspex Pharmaceuticals, Inc. | HIGHLY SELECTIVE and LONG-ACTING PDE5 MODULATORS |
| ES2395241T3 (es) * | 2007-03-07 | 2013-02-11 | Concert Pharmaceuticals Inc. | Derivados deuterados de piperazina como compuestos antianginosos |
| BRPI0916769A2 (pt) | 2008-07-15 | 2017-09-26 | Theracos Inc | derivados de benzilbenzeno deuterados e métodos de uso |
| CN102584592B (zh) * | 2011-12-28 | 2014-10-15 | 李进 | 一种氘代的拟除虫菊酯化合物及其制备方法和应用 |
| EP2882751B1 (en) | 2012-07-30 | 2018-06-27 | Concert Pharmaceuticals Inc. | Deuterated ibrutinib |
| CN111116492B (zh) * | 2019-01-25 | 2021-07-09 | 青岛吉澳医药科技有限公司 | 氘代苯甲氨嘧啶二酮衍生物及其用途 |
| WO2021236891A1 (en) * | 2020-05-20 | 2021-11-25 | Augusta University Research Institute, Inc. | Gut-targeted phosphodiesterase inhibitors |
| CN116444496B (zh) * | 2023-06-16 | 2023-11-24 | 药康众拓(北京)医药科技有限公司 | 一种嘧啶联氘代吡唑类化合物及其应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9013750D0 (en) * | 1990-06-20 | 1990-08-08 | Pfizer Ltd | Therapeutic agents |
| US5250534A (en) * | 1990-06-20 | 1993-10-05 | Pfizer Inc. | Pyrazolopyrimidinone antianginal agents |
-
2001
- 2001-11-07 DE DE10155018A patent/DE10155018A1/de not_active Ceased
-
2002
- 2002-11-07 CN CNA028254635A patent/CN1606557A/zh active Pending
- 2002-11-07 KR KR1020047007039A patent/KR20050044381A/ko not_active Withdrawn
- 2002-11-07 CZ CZ2004639A patent/CZ2004639A3/cs unknown
- 2002-11-07 US US10/494,914 patent/US20050069276A1/en not_active Abandoned
- 2002-11-07 CA CA002470271A patent/CA2470271A1/en not_active Abandoned
- 2002-11-07 HU HU0401721A patent/HUP0401721A3/hu unknown
- 2002-11-07 WO PCT/DE2002/004216 patent/WO2003039439A2/de not_active Ceased
- 2002-11-07 JP JP2003541731A patent/JP2005509646A/ja active Pending
- 2002-11-07 NZ NZ533385A patent/NZ533385A/en unknown
- 2002-11-07 PL PL02369654A patent/PL369654A1/xx not_active Application Discontinuation
- 2002-11-07 RU RU2004117157/04A patent/RU2004117157A/ru not_active Application Discontinuation
- 2002-11-07 IL IL16179002A patent/IL161790A0/xx unknown
- 2002-11-07 EP EP02779219A patent/EP1444234A2/de not_active Withdrawn
-
2004
- 2004-04-30 IS IS7246A patent/IS7246A/is unknown
- 2004-06-04 NO NO20042337A patent/NO20042337L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| PL369654A1 (en) | 2005-05-02 |
| HUP0401721A2 (hu) | 2005-08-29 |
| WO2003039439A2 (de) | 2003-05-15 |
| JP2005509646A (ja) | 2005-04-14 |
| RU2004117157A (ru) | 2006-01-10 |
| CZ2004639A3 (cs) | 2004-09-15 |
| CN1606557A (zh) | 2005-04-13 |
| EP1444234A2 (de) | 2004-08-11 |
| NZ533385A (en) | 2006-02-24 |
| NO20042337L (no) | 2004-06-04 |
| CA2470271A1 (en) | 2003-05-15 |
| US20050069276A1 (en) | 2005-03-31 |
| IS7246A (is) | 2004-04-30 |
| KR20050044381A (ko) | 2005-05-12 |
| WO2003039439A3 (de) | 2003-10-16 |
| DE10155018A1 (de) | 2003-07-10 |
| HUP0401721A3 (en) | 2005-11-28 |
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