IL159671A0 - New assays for preimplantation factor and preimplantation factor peptides - Google Patents
New assays for preimplantation factor and preimplantation factor peptidesInfo
- Publication number
- IL159671A0 IL159671A0 IL15967102A IL15967102A IL159671A0 IL 159671 A0 IL159671 A0 IL 159671A0 IL 15967102 A IL15967102 A IL 15967102A IL 15967102 A IL15967102 A IL 15967102A IL 159671 A0 IL159671 A0 IL 159671A0
- Authority
- IL
- Israel
- Prior art keywords
- pif
- present
- flow cytometry
- binding
- peptides
- Prior art date
Links
- 238000003556 assay Methods 0.000 title abstract 3
- GLXYOFXNKBTMQL-YKCHQESGSA-N (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-1-[(2S)-6-amino-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-4-methylsulfanylbutanoyl]amino]-3-methylbutanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylpentanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]propanoyl]amino]-4-oxobutanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxypropanoyl]amino]-3-carboxypropanoyl]amino]butanedioic acid Chemical compound CSCC[C@H](N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N1[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(O)=O)C(O)=O)CCC1 GLXYOFXNKBTMQL-YKCHQESGSA-N 0.000 title 2
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 238000000684 flow cytometry Methods 0.000 abstract 3
- 108010022347 proteolysis-inducing peptide Proteins 0.000 abstract 2
- 238000012286 ELISA Assay Methods 0.000 abstract 1
- 230000000781 anti-lymphocytic effect Effects 0.000 abstract 1
- 230000000702 anti-platelet effect Effects 0.000 abstract 1
- 239000003146 anticoagulant agent Substances 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000004113 cell culture Methods 0.000 abstract 1
- 230000003833 cell viability Effects 0.000 abstract 1
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4715—Pregnancy proteins, e.g. placenta proteins, alpha-feto-protein, pregnancy specific beta glycoprotein
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
- G01N2333/70507—C2D
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Genetics & Genomics (AREA)
- Pregnancy & Childbirth (AREA)
- Urology & Nephrology (AREA)
- Gynecology & Obstetrics (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Reproductive Health (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30260701P | 2001-07-02 | 2001-07-02 | |
| PCT/US2002/020599 WO2003004601A2 (en) | 2001-07-02 | 2002-06-28 | New assays for preimplantation factor and preimplantation factor peptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL159671A0 true IL159671A0 (en) | 2004-06-01 |
Family
ID=23168483
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL15967102A IL159671A0 (en) | 2001-07-02 | 2002-06-28 | New assays for preimplantation factor and preimplantation factor peptides |
| IL159671A IL159671A (en) | 2001-07-02 | 2003-12-31 | Preimplantation factor peptide |
| IL194710A IL194710A (en) | 2001-07-02 | 2008-10-12 | Pre-transplant peptide |
| IL209472A IL209472A (en) | 2001-07-02 | 2010-11-21 | Pre-transplant peptide |
| IL209481A IL209481A (en) | 2001-07-02 | 2010-11-21 | Pre-transplant peptide |
| IL209509A IL209509A (en) | 2001-07-02 | 2010-11-22 | Pre-transplant peptide |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL159671A IL159671A (en) | 2001-07-02 | 2003-12-31 | Preimplantation factor peptide |
| IL194710A IL194710A (en) | 2001-07-02 | 2008-10-12 | Pre-transplant peptide |
| IL209472A IL209472A (en) | 2001-07-02 | 2010-11-21 | Pre-transplant peptide |
| IL209481A IL209481A (en) | 2001-07-02 | 2010-11-21 | Pre-transplant peptide |
| IL209509A IL209509A (en) | 2001-07-02 | 2010-11-22 | Pre-transplant peptide |
Country Status (12)
| Country | Link |
|---|---|
| US (8) | US7273708B2 (https=) |
| EP (1) | EP1404877B1 (https=) |
| JP (1) | JP4593106B2 (https=) |
| CN (5) | CN101059510A (https=) |
| AT (1) | ATE454399T1 (https=) |
| AU (1) | AU2002320198B2 (https=) |
| CA (1) | CA2490538C (https=) |
| DE (1) | DE60235011D1 (https=) |
| IL (6) | IL159671A0 (https=) |
| MX (1) | MXPA04000151A (https=) |
| NZ (1) | NZ530723A (https=) |
| WO (1) | WO2003004601A2 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8222211B2 (en) * | 2001-07-02 | 2012-07-17 | Bioincept, Llc | Methods of administering PIF agonist peptides and uses thereof |
| US7273708B2 (en) * | 2001-07-02 | 2007-09-25 | Bioincept, Llc | Assays for preimplantation factor and preimplantation factor peptides |
| US7723290B2 (en) * | 2004-10-22 | 2010-05-25 | Bioincept, Llc | Compositions and methods for modulating the immune system |
| EP1680442B1 (en) * | 2003-10-22 | 2011-07-13 | Bioincept, LLC. | Pif peptides biologic activities |
| WO2005040196A2 (en) | 2003-10-22 | 2005-05-06 | Bioincept, Llc | Pif peptides biologic activities, site of action, and the antibody to detect pif |
| US7723289B2 (en) * | 2003-10-22 | 2010-05-25 | Bioincept, Llc | PIF tetrapeptides |
| US9737585B2 (en) | 2011-03-02 | 2017-08-22 | Bioincept, Llc | Compositions and methods for treatment of intracellular damage and bacterial infection |
| WO2017039751A1 (en) | 2015-08-28 | 2017-03-09 | Bioincept, Llc | Mutant peptides and methods of treating subjects using the same |
| EP2970496B1 (en) | 2013-03-12 | 2018-07-18 | Institute of Arthritis Research LLC | Immunologically active polypeptide |
| AU2015343202A1 (en) * | 2014-11-03 | 2017-05-25 | Bioincept, Llc | PIF binding as a marker for immune dysregulation |
| EP3341006A4 (en) | 2015-08-28 | 2019-03-13 | BioIncept LLC | COMPOSITIONS AND METHODS FOR TREATING NERVE DAMAGE |
| CA3054366A1 (en) * | 2017-02-22 | 2018-08-30 | Bioincept, Llc | Peptides and methods of treating dystrophy-related disorders using the same |
| US20240228620A1 (en) | 2022-10-06 | 2024-07-11 | Bicara Therapeutics Inc. | Multispecific proteins and related methods |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US564003A (en) * | 1896-07-14 | chase | ||
| US6352694B1 (en) | 1994-06-03 | 2002-03-05 | Genetics Institute, Inc. | Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells |
| US5279941A (en) | 1992-06-12 | 1994-01-18 | Trustees Of The University Of Pennsylvania | Determination of endometrial receptivity toward embryo implantation |
| AU5130793A (en) * | 1992-09-17 | 1994-04-12 | New York University | Compositions and methods for inhibiting hepatocyte invasion by malarial sporozoites |
| US5646003A (en) | 1994-03-23 | 1997-07-08 | Barnea; Eytan R. | Preimplantation factor |
| GB9406492D0 (en) | 1994-03-31 | 1994-05-25 | Isis Innovation | Malaria peptides |
| US6489441B1 (en) * | 1995-09-01 | 2002-12-03 | The Salk Institute For Biological Studies | Transcriptional co-repressor that interacts with nuclear hormone receptors |
| US6585979B1 (en) | 1996-07-08 | 2003-07-01 | Genentech, Inc. | HIV envelope polypeptides and immunogenic composition |
| US6171591B1 (en) * | 1997-12-08 | 2001-01-09 | Pentamer Pharmaceuticals, Inc. | Recombinant nodavirus compositions and methods |
| US20020004205A1 (en) | 2000-03-30 | 2002-01-10 | Consler Thomas G. | Method of investigating functional molecular interactions and reagents for use therein |
| EP1355664A4 (en) | 2001-01-04 | 2005-10-26 | Vascular Biogenics Ltd | METHODS INVOLVING MOLECULES ASSOCIATED WITH ATHEROSCLEROSIS PLATES AND COMPOSITIONS CONTAINING THESE MOLECULES FOR THE PREVENTION AND TREATMENT OF ATHEROSCLEROSIS |
| US8222211B2 (en) | 2001-07-02 | 2012-07-17 | Bioincept, Llc | Methods of administering PIF agonist peptides and uses thereof |
| US7273708B2 (en) | 2001-07-02 | 2007-09-25 | Bioincept, Llc | Assays for preimplantation factor and preimplantation factor peptides |
| WO2004053086A2 (en) | 2002-12-06 | 2004-06-24 | Epimmune, Inc. | Plasmodium falciparum antigens and methods of use |
| US7156272B2 (en) * | 2003-08-22 | 2007-01-02 | Frank Dean | Golf bag carrier for a motorcycle |
| US7723289B2 (en) | 2003-10-22 | 2010-05-25 | Bioincept, Llc | PIF tetrapeptides |
| US7723290B2 (en) | 2004-10-22 | 2010-05-25 | Bioincept, Llc | Compositions and methods for modulating the immune system |
| WO2005040196A2 (en) | 2003-10-22 | 2005-05-06 | Bioincept, Llc | Pif peptides biologic activities, site of action, and the antibody to detect pif |
-
2002
- 2002-06-28 US US10/482,244 patent/US7273708B2/en not_active Expired - Lifetime
- 2002-06-28 DE DE60235011T patent/DE60235011D1/de not_active Expired - Lifetime
- 2002-06-28 CN CNA2007100864051A patent/CN101059510A/zh active Pending
- 2002-06-28 CN CNB028133196A patent/CN100339388C/zh not_active Expired - Lifetime
- 2002-06-28 AU AU2002320198A patent/AU2002320198B2/en not_active Expired
- 2002-06-28 CN CN201310654136.XA patent/CN103755787B/zh not_active Expired - Fee Related
- 2002-06-28 JP JP2003510760A patent/JP4593106B2/ja not_active Expired - Fee Related
- 2002-06-28 MX MXPA04000151A patent/MXPA04000151A/es active IP Right Grant
- 2002-06-28 IL IL15967102A patent/IL159671A0/xx unknown
- 2002-06-28 CA CA2490538A patent/CA2490538C/en not_active Expired - Lifetime
- 2002-06-28 NZ NZ530723A patent/NZ530723A/en not_active IP Right Cessation
- 2002-06-28 EP EP02749703A patent/EP1404877B1/en not_active Expired - Lifetime
- 2002-06-28 CN CN201110025233.3A patent/CN102174079B/zh not_active Expired - Fee Related
- 2002-06-28 CN CN201210307132.XA patent/CN102875646B/zh not_active Expired - Fee Related
- 2002-06-28 AT AT02749703T patent/ATE454399T1/de not_active IP Right Cessation
- 2002-06-28 WO PCT/US2002/020599 patent/WO2003004601A2/en not_active Ceased
-
2003
- 2003-12-31 IL IL159671A patent/IL159671A/en unknown
-
2007
- 2007-09-14 US US11/855,495 patent/US7670850B2/en not_active Expired - Fee Related
- 2007-09-14 US US11/855,519 patent/US7678582B2/en not_active Expired - Fee Related
- 2007-09-14 US US11/855,586 patent/US7670852B2/en not_active Expired - Fee Related
- 2007-09-14 US US11/855,539 patent/US7670851B2/en not_active Expired - Fee Related
- 2007-09-14 US US11/855,616 patent/US7695977B2/en not_active Expired - Fee Related
-
2008
- 2008-10-12 IL IL194710A patent/IL194710A/en active IP Right Grant
-
2010
- 2010-01-26 US US12/693,854 patent/US8012700B2/en not_active Expired - Fee Related
- 2010-11-21 IL IL209472A patent/IL209472A/en not_active IP Right Cessation
- 2010-11-21 IL IL209481A patent/IL209481A/en not_active IP Right Cessation
- 2010-11-22 IL IL209509A patent/IL209509A/en not_active IP Right Cessation
-
2011
- 2011-08-12 US US13/208,801 patent/US20120009605A1/en not_active Abandoned
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