IL158495A0 - A two-step method for producing paclitaxel - Google Patents

A two-step method for producing paclitaxel

Info

Publication number
IL158495A0
IL158495A0 IL15849502A IL15849502A IL158495A0 IL 158495 A0 IL158495 A0 IL 158495A0 IL 15849502 A IL15849502 A IL 15849502A IL 15849502 A IL15849502 A IL 15849502A IL 158495 A0 IL158495 A0 IL 158495A0
Authority
IL
Israel
Prior art keywords
step method
producing paclitaxel
paclitaxel
producing
Prior art date
Application number
IL15849502A
Other languages
English (en)
Original Assignee
Napro Biotherapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Napro Biotherapeutics Inc filed Critical Napro Biotherapeutics Inc
Publication of IL158495A0 publication Critical patent/IL158495A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
IL15849502A 2001-04-25 2002-04-25 A two-step method for producing paclitaxel IL158495A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/843,284 US6479679B1 (en) 2001-04-25 2001-04-25 Two-step conversion of protected taxane ester to paclitaxel
PCT/US2002/013183 WO2002085878A1 (en) 2001-04-25 2002-04-25 Two-step conversion of protected taxane ester to paclitaxel

Publications (1)

Publication Number Publication Date
IL158495A0 true IL158495A0 (en) 2004-05-12

Family

ID=25289535

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15849502A IL158495A0 (en) 2001-04-25 2002-04-25 A two-step method for producing paclitaxel

Country Status (8)

Country Link
US (1) US6479679B1 (xx)
EP (1) EP1389197A4 (xx)
JP (1) JP2004529153A (xx)
CA (1) CA2445042A1 (xx)
IL (1) IL158495A0 (xx)
NO (1) NO20034639L (xx)
NZ (1) NZ531444A (xx)
WO (1) WO2002085878A1 (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2503265T3 (es) * 2002-08-04 2014-10-06 Phyton Holdings, Llc Métodos para convertir amidas de taxano en paclitaxel u otros taxanos
AU2006258065A1 (en) 2005-06-10 2006-12-21 Florida State University Research Foundation, Inc. Processes for the production of polycyclic fused ring compounds
JP5113745B2 (ja) 2005-06-10 2013-01-09 フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド ドセタキセルの製造法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601676B1 (fr) 1986-07-17 1988-09-23 Rhone Poulenc Sante Procede de preparation du taxol et du desacetyl-10 taxol
FR2601675B1 (fr) 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
USRE34277E (en) 1988-04-06 1993-06-08 Centre National De La Recherche Scientifique Process for preparing taxol
FR2629818B1 (fr) 1988-04-06 1990-11-16 Centre Nat Rech Scient Procede de preparation du taxol
FR2629819B1 (fr) 1988-04-06 1990-11-16 Rhone Poulenc Sante Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii
US4960790A (en) 1989-03-09 1990-10-02 University Of Kansas Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof
US5175315A (en) 1989-05-31 1992-12-29 Florida State University Method for preparation of taxol using β-lactam
US5136060A (en) 1989-11-14 1992-08-04 Florida State University Method for preparation of taxol using an oxazinone
US5015744A (en) 1989-11-14 1991-05-14 Florida State University Method for preparation of taxol using an oxazinone
FR2658513B1 (fr) 1990-02-21 1994-02-04 Rhone Poulenc Sante Procede de preparation de l'acide cis-beta-phenylglycidique-(2r,3r).
US5684175A (en) 1993-02-05 1997-11-04 Napro Biotherapeutics, Inc. C-2' hydroxyl-benzyl protected, N-carbamate protected (2R, 3S)- 3-phenylisoserine and production process therefor
CA2155304C (en) 1993-02-05 2010-07-20 Charles Swindell Syntheses of paclitaxel, analogs and intermediates with variable a-ring side chains
US5750737A (en) 1996-09-25 1998-05-12 Sisti; Nicholas J. Method for paclitaxel synthesis
US5973170A (en) 1996-09-25 1999-10-26 Napro Biotherapuetics, Inc. C-7 metal alkoxides of baccatin III
JP4502338B2 (ja) * 1999-09-17 2010-07-14 株式会社横浜国際バイオ研究所 タキソイド化合物の製造法

Also Published As

Publication number Publication date
NO20034639L (no) 2003-12-01
WO2002085878A1 (en) 2002-10-31
EP1389197A4 (en) 2004-07-28
CA2445042A1 (en) 2002-10-31
US6479679B1 (en) 2002-11-12
JP2004529153A (ja) 2004-09-24
EP1389197A1 (en) 2004-02-18
NO20034639D0 (no) 2003-10-17
NZ531444A (en) 2004-06-25

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