IL157909A0 - Indolopyrrolocarbazole derivatives and pharmaceutical compositions containing the same - Google Patents
Indolopyrrolocarbazole derivatives and pharmaceutical compositions containing the sameInfo
- Publication number
- IL157909A0 IL157909A0 IL15790902A IL15790902A IL157909A0 IL 157909 A0 IL157909 A0 IL 157909A0 IL 15790902 A IL15790902 A IL 15790902A IL 15790902 A IL15790902 A IL 15790902A IL 157909 A0 IL157909 A0 IL 157909A0
- Authority
- IL
- Israel
- Prior art keywords
- same
- pharmaceutical compositions
- compositions containing
- indolopyrrolocarbazole derivatives
- indolopyrrolocarbazole
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/044—Pyrrole radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/23—Heterocyclic radicals containing two or more heterocyclic rings condensed among themselves or condensed with a common carbocyclic ring system, not provided for in groups C07H19/14 - C07H19/22
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27804301P | 2001-03-22 | 2001-03-22 | |
| PCT/US2002/008819 WO2002077255A1 (en) | 2001-03-22 | 2002-03-22 | Topoisomerase i selective cytotoxic sugar derivatives of indolopyrrolocarbazoles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL157909A0 true IL157909A0 (en) | 2004-03-28 |
Family
ID=23063451
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL15790902A IL157909A0 (en) | 2001-03-22 | 2002-03-22 | Indolopyrrolocarbazole derivatives and pharmaceutical compositions containing the same |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US6855698B2 (no) |
| EP (1) | EP1370673A4 (no) |
| JP (1) | JP2004534006A (no) |
| KR (1) | KR20030085035A (no) |
| CN (1) | CN1509335A (no) |
| BG (1) | BG108183A (no) |
| BR (1) | BR0208322A (no) |
| CA (1) | CA2441412A1 (no) |
| CZ (1) | CZ20032876A3 (no) |
| EE (1) | EE200300456A (no) |
| HR (1) | HRP20030761A2 (no) |
| HU (1) | HUP0400265A2 (no) |
| IL (1) | IL157909A0 (no) |
| IS (1) | IS6958A (no) |
| MX (1) | MXPA03008589A (no) |
| NO (1) | NO20034190L (no) |
| PL (1) | PL368942A1 (no) |
| RU (1) | RU2003131269A (no) |
| SK (1) | SK12022003A3 (no) |
| WO (1) | WO2002077255A1 (no) |
| YU (1) | YU74103A (no) |
| ZA (1) | ZA200307317B (no) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2326459B1 (es) | 2008-04-08 | 2010-05-28 | Universidad De Oviedo | Indolocarbazoles glicosilados, su procedimiento de obtencion y sus usos. |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4552842A (en) | 1983-01-28 | 1985-11-12 | Bristol-Myers Company | Process for producing rebeccamycin |
| US4487925A (en) | 1983-01-28 | 1984-12-11 | Bristol-Myers Company | Rebeccamycin and process for its preparation |
| US4567143A (en) | 1984-09-04 | 1986-01-28 | Bristol-Myers Company | Process for preparing 4'-deschlororebeccamycin |
| US4785085A (en) | 1986-11-21 | 1988-11-15 | Bristol-Myers Company | Rebeccamycin analogs |
| JP2766360B2 (ja) | 1988-02-04 | 1998-06-18 | 協和醗酵工業株式会社 | スタウロスポリン誘導体 |
| DE3803620A1 (de) | 1988-02-06 | 1989-08-17 | Goedecke Ag | Indolocarbazol-derivate, verfahren zu deren herstellung und diese enthaltende arzneimittel |
| DE3924538A1 (de) | 1989-07-25 | 1991-01-31 | Goedecke Ag | Indolocarbazol und dessen verwendung |
| US5618809A (en) | 1989-12-14 | 1997-04-08 | Schering Corporation | Indolocarbazoles from saccharothrix aerocolonigenes copiosa subsp. nov SCC 1951 ATCC 53856 |
| IL97233A (en) | 1990-03-06 | 1995-03-30 | Bristol Myers Squibb Co | Analogs of rabamycin, their manufacture and pharmaceutical preparations containing them |
| US5478813A (en) | 1990-05-11 | 1995-12-26 | Banyu Pharmaceutical Co., Ltd. | Antitumor substance BE-13793C derivatives |
| US5589365A (en) * | 1991-11-29 | 1996-12-31 | Banyu Pharmaceutical Co., Ltd. | Process for producing glycosylated indolopyrrolocarbazole derivatives by culturing certain microorganisms |
| NZ245203A (en) | 1991-11-29 | 1997-07-27 | Banyu Pharma Co Ltd | 5h-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6h)-dione derivatives substituted in position-13 by a pentose or hexose group; corresponding indolo-furano(anhydride)intermediates |
| US5668271A (en) | 1991-11-29 | 1997-09-16 | Banyu Pharmaceutical Co., Ltd. | Indolopyrrolocarbazole derivatives |
| DE69331228T4 (de) | 1992-09-21 | 2002-09-05 | Kyowa Hakko Kogyo Co., Ltd. | Heilmittel für thrombozytopenia |
| FR2696465B1 (fr) | 1992-10-02 | 1994-12-23 | Adir | Nouveaux dérivés d'ellipticine, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
| JP3603322B2 (ja) | 1992-12-14 | 2004-12-22 | 萬有製薬株式会社 | インドロピロロカルバゾール誘導体の製造法 |
| US5468872A (en) | 1993-09-16 | 1995-11-21 | Cephalon, Inc. | K-252a functional derivatives potentiate neurotrophin-3 for the treatment of neurological disorders |
| WO1995030682A1 (fr) | 1994-05-09 | 1995-11-16 | Banyu Pharmaceutical Co., Ltd. | Derive d'indolopyrolocarbazole antitumoral |
| WO1996004293A1 (fr) | 1994-08-02 | 1996-02-15 | Banyu Pharmaceutical Co., Ltd. | Indolopyrrolocarbazoles antitumoraux |
| US5475110A (en) | 1994-10-14 | 1995-12-12 | Cephalon, Inc. | Fused Pyrrolocarbazoles |
| US5705511A (en) | 1994-10-14 | 1998-01-06 | Cephalon, Inc. | Fused pyrrolocarbazoles |
| AU6888196A (en) | 1995-08-11 | 1997-03-12 | Yale University | Glycosylated indolocarbazole synthesis |
| JP2000516250A (ja) * | 1996-08-22 | 2000-12-05 | ブリストルーマイヤーズ スクイブ カンパニー | インドロピロロカルバゾールの細胞毒性アミノ糖および関連する糖誘導体 |
| CO4940430A1 (es) | 1997-07-07 | 2000-07-24 | Novartis Ag | Compuestos policiclicos que contienen estaurosporina hidrogenada con propiedades farmacologicas convenientes y un efecto inhibidor sobre el crecimiento de las celulas tumorales |
| FR2801054B1 (fr) | 1999-11-17 | 2003-06-13 | Adir | Nouveaux derives de 12,13-(pyranosyl)-indolo[2,3-a]pyrrolo [3,4-c]carbazole et 12,13-(pyranosyl)-furo[3,4-c]indolo [2,3-a]carbazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
-
2002
- 2002-03-22 WO PCT/US2002/008819 patent/WO2002077255A1/en not_active Application Discontinuation
- 2002-03-22 KR KR10-2003-7012321A patent/KR20030085035A/ko not_active Application Discontinuation
- 2002-03-22 PL PL02368942A patent/PL368942A1/xx not_active Application Discontinuation
- 2002-03-22 RU RU2003131269/04A patent/RU2003131269A/ru not_active Application Discontinuation
- 2002-03-22 CN CNA028102320A patent/CN1509335A/zh active Pending
- 2002-03-22 EP EP02753812A patent/EP1370673A4/en not_active Withdrawn
- 2002-03-22 IL IL15790902A patent/IL157909A0/xx unknown
- 2002-03-22 SK SK1202-2003A patent/SK12022003A3/sk not_active Application Discontinuation
- 2002-03-22 YU YU74103A patent/YU74103A/sh unknown
- 2002-03-22 CZ CZ20032876A patent/CZ20032876A3/cs unknown
- 2002-03-22 BR BR0208322-1A patent/BR0208322A/pt not_active IP Right Cessation
- 2002-03-22 US US10/103,908 patent/US6855698B2/en not_active Expired - Lifetime
- 2002-03-22 EE EEP200300456A patent/EE200300456A/xx unknown
- 2002-03-22 CA CA002441412A patent/CA2441412A1/en not_active Abandoned
- 2002-03-22 JP JP2002576696A patent/JP2004534006A/ja not_active Withdrawn
- 2002-03-22 MX MXPA03008589A patent/MXPA03008589A/es unknown
- 2002-03-22 HU HU0400265A patent/HUP0400265A2/hu unknown
-
2003
- 2003-09-16 IS IS6958A patent/IS6958A/is unknown
- 2003-09-18 BG BG108183A patent/BG108183A/xx unknown
- 2003-09-18 ZA ZA200307317A patent/ZA200307317B/en unknown
- 2003-09-19 HR HR20030761A patent/HRP20030761A2/xx not_active Application Discontinuation
- 2003-09-19 NO NO20034190A patent/NO20034190L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CZ20032876A3 (en) | 2004-03-17 |
| ZA200307317B (en) | 2004-12-20 |
| SK12022003A3 (sk) | 2004-05-04 |
| IS6958A (is) | 2003-09-16 |
| PL368942A1 (en) | 2005-04-04 |
| EP1370673A4 (en) | 2006-08-09 |
| US6855698B2 (en) | 2005-02-15 |
| HUP0400265A2 (hu) | 2004-08-30 |
| MXPA03008589A (es) | 2003-12-08 |
| CA2441412A1 (en) | 2002-10-03 |
| CN1509335A (zh) | 2004-06-30 |
| HRP20030761A2 (en) | 2004-04-30 |
| BR0208322A (pt) | 2004-10-13 |
| EP1370673A1 (en) | 2003-12-17 |
| RU2003131269A (ru) | 2005-05-10 |
| YU74103A (sh) | 2006-05-25 |
| BG108183A (en) | 2004-07-30 |
| KR20030085035A (ko) | 2003-11-01 |
| JP2004534006A (ja) | 2004-11-11 |
| US20030083271A1 (en) | 2003-05-01 |
| NO20034190L (no) | 2003-11-19 |
| WO2002077255A1 (en) | 2002-10-03 |
| EE200300456A (et) | 2004-02-16 |
| NO20034190D0 (no) | 2003-09-19 |
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