IL157649A0 - Adenosine derivatives having an acetylene group in the 4' position, pharmaceutical compositions containing them and use thereof in decreasing plasma free fatty acid concentration - Google Patents

Adenosine derivatives having an acetylene group in the 4' position, pharmaceutical compositions containing them and use thereof in decreasing plasma free fatty acid concentration

Info

Publication number
IL157649A0
IL157649A0 IL15764902A IL15764902A IL157649A0 IL 157649 A0 IL157649 A0 IL 157649A0 IL 15764902 A IL15764902 A IL 15764902A IL 15764902 A IL15764902 A IL 15764902A IL 157649 A0 IL157649 A0 IL 157649A0
Authority
IL
Israel
Prior art keywords
fatty acid
pharmaceutical compositions
compositions containing
acid concentration
free fatty
Prior art date
Application number
IL15764902A
Other languages
English (en)
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0106877A external-priority patent/GB0106877D0/en
Priority claimed from GB0106871A external-priority patent/GB0106871D0/en
Priority claimed from GB0106875A external-priority patent/GB0106875D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of IL157649A0 publication Critical patent/IL157649A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
IL15764902A 2001-03-20 2002-03-19 Adenosine derivatives having an acetylene group in the 4' position, pharmaceutical compositions containing them and use thereof in decreasing plasma free fatty acid concentration IL157649A0 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0106877A GB0106877D0 (en) 2001-03-20 2001-03-20 Chemical compounds
GB0106871A GB0106871D0 (en) 2001-03-20 2001-03-20 Chemical compounds
GB0106875A GB0106875D0 (en) 2001-03-20 2001-03-20 Medicaments
PCT/GB2002/001317 WO2002074780A1 (en) 2001-03-20 2002-03-19 Chemical compounds

Publications (1)

Publication Number Publication Date
IL157649A0 true IL157649A0 (en) 2004-05-12

Family

ID=27256108

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15764902A IL157649A0 (en) 2001-03-20 2002-03-19 Adenosine derivatives having an acetylene group in the 4' position, pharmaceutical compositions containing them and use thereof in decreasing plasma free fatty acid concentration

Country Status (18)

Country Link
US (1) US20040162422A1 (no)
EP (1) EP1370568B1 (no)
JP (1) JP2004534002A (no)
KR (1) KR20030085014A (no)
CN (1) CN1501941A (no)
AR (1) AR037135A1 (no)
AT (1) ATE306492T1 (no)
BR (1) BR0208169A (no)
CA (1) CA2441202A1 (no)
CZ (1) CZ20032543A3 (no)
DE (1) DE60206605D1 (no)
HU (1) HUP0303533A3 (no)
IL (1) IL157649A0 (no)
MX (1) MXPA03008493A (no)
NO (1) NO20034182D0 (no)
NZ (1) NZ527854A (no)
PL (1) PL364712A1 (no)
WO (1) WO2002074780A1 (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100480255C (zh) * 2002-08-15 2009-04-22 Cv医药有限公司 A1腺苷受体的部分和完全激动剂
GB0221694D0 (en) * 2002-09-18 2002-10-30 Glaxo Group Ltd Compounds
GT200500281A (es) * 2004-10-22 2006-04-24 Novartis Ag Compuestos organicos.
GB0500785D0 (en) 2005-01-14 2005-02-23 Novartis Ag Organic compounds
GB0607948D0 (en) * 2006-04-21 2006-05-31 Novartis Ag Organic compounds
SI2013211T1 (sl) * 2006-04-21 2012-07-31 Novartis Ag Purinski derivati za uporabo kot agonisti receptorja adenozina A A
GB0607950D0 (en) * 2006-04-21 2006-05-31 Novartis Ag Organic compounds
GB0607944D0 (en) * 2006-04-21 2006-05-31 Novartis Ag Organic compounds
GB0607945D0 (en) * 2006-04-21 2006-05-31 Novartis Ag Organic compounds
GB0607953D0 (en) * 2006-04-21 2006-05-31 Novartis Ag Organic compounds
EP1889846A1 (en) 2006-07-13 2008-02-20 Novartis AG Purine derivatives as A2a agonists
EP1903044A1 (en) * 2006-09-14 2008-03-26 Novartis AG Adenosine Derivatives as A2A Receptor Agonists
RU2009121819A (ru) * 2006-11-10 2010-12-20 Новартис АГ (CH) Производные моноацетата циклопентендиола
AU2008313789A1 (en) * 2007-10-17 2009-04-23 Novartis Ag Purine derivatives as adenosine AL receptor ligands

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4996308A (en) * 1988-03-25 1991-02-26 Merrell Dow Pharmaceuticals Inc. Derivatives with unsaturated substitutions for the 5'-hydroxymethyl group
GB9723589D0 (en) * 1997-11-08 1998-01-07 Glaxo Group Ltd Chemical compounds
YU44900A (sh) * 1998-01-31 2003-01-31 Glaxo Group Limited Derivati 2-(purin-9-il)tetrahidrofuran-3,4-diola
GB9813554D0 (en) * 1998-06-23 1998-08-19 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
ATE306492T1 (de) 2005-10-15
US20040162422A1 (en) 2004-08-19
EP1370568B1 (en) 2005-10-12
PL364712A1 (en) 2004-12-13
CN1501941A (zh) 2004-06-02
CZ20032543A3 (en) 2004-05-12
NO20034182L (no) 2003-09-19
BR0208169A (pt) 2004-03-02
KR20030085014A (ko) 2003-11-01
CA2441202A1 (en) 2002-09-26
HUP0303533A2 (hu) 2004-03-01
NO20034182D0 (no) 2003-09-19
AR037135A1 (es) 2004-10-27
WO2002074780A1 (en) 2002-09-26
DE60206605D1 (de) 2006-02-23
JP2004534002A (ja) 2004-11-11
EP1370568A1 (en) 2003-12-17
MXPA03008493A (es) 2003-12-08
NZ527854A (en) 2004-09-24
HUP0303533A3 (en) 2005-02-28

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