IL156917A0 - Method and apparatus to remove substances from vessels of the heart and other parts of the body to minimize or avoid renal or other harm or dysfunction - Google Patents
Method and apparatus to remove substances from vessels of the heart and other parts of the body to minimize or avoid renal or other harm or dysfunctionInfo
- Publication number
- IL156917A0 IL156917A0 IL15691702A IL15691702A IL156917A0 IL 156917 A0 IL156917 A0 IL 156917A0 IL 15691702 A IL15691702 A IL 15691702A IL 15691702 A IL15691702 A IL 15691702A IL 156917 A0 IL156917 A0 IL 156917A0
- Authority
- IL
- Israel
- Prior art keywords
- dysfunction
- harm
- vessels
- heart
- minimize
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3613—Reperfusion, e.g. of the coronary vessels, e.g. retroperfusion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3653—Interfaces between patient blood circulation and extra-corporal blood circuit
- A61M1/3659—Cannulae pertaining to extracorporeal circulation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M2025/1043—Balloon catheters with special features or adapted for special applications
- A61M2025/1052—Balloon catheters with special features or adapted for special applications for temporarily occluding a vessel for isolating a sector
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/007—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests for contrast media
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- External Artificial Organs (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26386501P | 2001-01-23 | 2001-01-23 | |
| PCT/US2002/002031 WO2002058777A2 (en) | 2001-01-23 | 2002-01-23 | Method and apparatus to remove substances from vessels of the heart and other parts of the body to minimize or avoid renal or other harm or dysfunction |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL156917A0 true IL156917A0 (en) | 2004-02-08 |
Family
ID=23003568
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL15691702A IL156917A0 (en) | 2001-01-23 | 2002-01-23 | Method and apparatus to remove substances from vessels of the heart and other parts of the body to minimize or avoid renal or other harm or dysfunction |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US7363072B2 (https=) |
| EP (1) | EP1353721A2 (https=) |
| JP (1) | JP2005503183A (https=) |
| AU (1) | AU2002235462A1 (https=) |
| CA (1) | CA2434515A1 (https=) |
| IL (1) | IL156917A0 (https=) |
| MX (1) | MXPA03006557A (https=) |
| WO (1) | WO2002058777A2 (https=) |
Families Citing this family (62)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7163520B2 (en) | 2002-06-26 | 2007-01-16 | Chf Solutions, Inc. | Method and device for removal of radiocontrast media from blood |
| US8388604B2 (en) * | 2003-02-21 | 2013-03-05 | Dtherapeutics, Llc | Devices, systems, and methods for removing contrast from luminal organs |
| CA2519376A1 (en) * | 2003-03-18 | 2004-09-30 | Dyerx Medical Inc. | Methods and devices for retrieval of a medical agent from a physiological efferent fluid collection site |
| US7300429B2 (en) * | 2003-03-18 | 2007-11-27 | Catharos Medical Systems, Inc. | Methods and devices for retrieval of a medical agent from a physiological efferent fluid collection site |
| US20070203445A1 (en) * | 2004-02-26 | 2007-08-30 | V-Kardia Pty Ltd | Isolating cardiac circulation |
| US7722596B2 (en) * | 2004-02-26 | 2010-05-25 | Osprey Medical, Inc. | Regional cardiac tissue treatment |
| JP4223980B2 (ja) * | 2004-03-16 | 2009-02-12 | 株式会社日立エルジーデータストレージ | 光ディスク装置及びその光ピックアップの摺動駆動機構 |
| US7899512B2 (en) * | 2004-03-22 | 2011-03-01 | Vanderbilt University | System and method for surgical instrument disablement via image-guided position feedback |
| WO2006004882A1 (en) * | 2004-06-30 | 2006-01-12 | University Of Vermont And State Agricultural College | Method and device to recover diagnostic and therapeutic agents |
| US7819856B2 (en) * | 2004-10-05 | 2010-10-26 | Nexeon Medical Systems, Inc. | Methods and apparatus for treating infarcted regions of tissue following acute myocardial infarction |
| US20060074294A1 (en) * | 2004-10-06 | 2006-04-06 | E-Z-Em, Inc. | Medical imaging system, dispensing system, method, and computer program product for assessing patient renal function prior to dispensing a contrast media as part of a medical imaging procedure |
| CN102488527B (zh) | 2004-11-16 | 2015-06-10 | 拜耳医疗保健公司 | 从成像过程确定病人生理参数的系统和方法 |
| DK2990073T3 (en) | 2004-11-24 | 2018-08-13 | Bayer Healthcare Llc | DEVICES AND SYSTEMS FOR DELIVERING FLUIDS |
| JP2006263455A (ja) * | 2005-02-22 | 2006-10-05 | Kaneka Corp | 造影剤除去システム |
| WO2006090706A1 (ja) * | 2005-02-22 | 2006-08-31 | Kaneka Corporation | 造影剤除去システムおよび該造影剤除去システムの作動方法 |
| JP2007089768A (ja) * | 2005-09-28 | 2007-04-12 | Kaneka Corp | 造影剤除去システム |
| AU2006284540A1 (en) * | 2005-08-25 | 2007-03-01 | Osprey Medical Inc. | Devices and methods for perfusing an organ |
| US20070129630A1 (en) * | 2005-12-07 | 2007-06-07 | Shimko Daniel A | Imaging method, device and system |
| US20090187131A1 (en) * | 2006-03-02 | 2009-07-23 | Fitzgerald Peter J | Methods and devices for retrieval of a medical agent from a physiological efferent fluid collection site |
| US20080125746A1 (en) * | 2006-08-18 | 2008-05-29 | James Edward Shapland | Collection catheter and method |
| US8152786B2 (en) * | 2006-11-07 | 2012-04-10 | Osprey Medical, Inc. | Collection catheter and kit |
| US9302044B2 (en) | 2006-12-29 | 2016-04-05 | Bayer Healthcare Llc | Patient-based parameter generation systems for medical injection procedures |
| WO2008122048A2 (en) * | 2007-04-02 | 2008-10-09 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Removal of contrast agents from blood |
| WO2008157256A1 (en) * | 2007-06-13 | 2008-12-24 | Catharos Medical Systems, Inc. | Methods and devices for removal of a medical agent from a physiological efferent fluid collection site |
| EP2170165B1 (en) | 2007-07-17 | 2018-12-05 | Bayer Healthcare LLC | Systems for determination of parameters for a procedure, for estimation of cardiopulmonary function and for fluid delivery |
| US8986253B2 (en) | 2008-01-25 | 2015-03-24 | Tandem Diabetes Care, Inc. | Two chamber pumps and related methods |
| WO2010008986A2 (en) * | 2008-07-18 | 2010-01-21 | Catharos Medical Systems, Inc. | Methods and devices for endovascular introduction of an agent |
| US20100041984A1 (en) * | 2008-08-12 | 2010-02-18 | James Edward Shapland | Impedance sensing device and catheter system |
| US9050400B2 (en) * | 2008-08-12 | 2015-06-09 | Osprey Medical, Inc. | Remote sensing catheter system and methods |
| US8133199B2 (en) * | 2008-08-27 | 2012-03-13 | Boston Scientific Scimed, Inc. | Electroactive polymer activation system for a medical device |
| US8408421B2 (en) | 2008-09-16 | 2013-04-02 | Tandem Diabetes Care, Inc. | Flow regulating stopcocks and related methods |
| AU2009293019A1 (en) | 2008-09-19 | 2010-03-25 | Tandem Diabetes Care Inc. | Solute concentration measurement device and related methods |
| US9421330B2 (en) | 2008-11-03 | 2016-08-23 | Bayer Healthcare Llc | Mitigation of contrast-induced nephropathy |
| EP2376175B1 (en) * | 2008-12-12 | 2019-01-30 | Corindus, Inc. | Remote catheter procedure system |
| EP3284494A1 (en) | 2009-07-30 | 2018-02-21 | Tandem Diabetes Care, Inc. | Portable infusion pump system |
| US9295816B2 (en) | 2009-12-09 | 2016-03-29 | Osprey Medical, Inc. | Catheter with distal and proximal ports |
| WO2011163578A2 (en) | 2010-06-24 | 2011-12-29 | Medrad, Inc. | Modeling of pharmaceutical propagation and parameter generation for injection protocols |
| US9211372B2 (en) | 2011-08-11 | 2015-12-15 | Osprey Medical, Inc. | Systems and methods for limb treatment |
| US12096951B2 (en) * | 2011-10-05 | 2024-09-24 | Penumbra, Inc. | System and method for treating ischemic stroke |
| DE102011085597A1 (de) * | 2011-11-02 | 2013-05-02 | Siemens Aktiengesellschaft | Medizinische Untersuchungsvorrichtung |
| US9949704B2 (en) | 2012-05-14 | 2018-04-24 | Bayer Healthcare Llc | Systems and methods for determination of pharmaceutical fluid injection protocols based on x-ray tube voltage |
| US9180242B2 (en) | 2012-05-17 | 2015-11-10 | Tandem Diabetes Care, Inc. | Methods and devices for multiple fluid transfer |
| US9555186B2 (en) | 2012-06-05 | 2017-01-31 | Tandem Diabetes Care, Inc. | Infusion pump system with disposable cartridge having pressure venting and pressure feedback |
| US9555379B2 (en) | 2013-03-13 | 2017-01-31 | Bayer Healthcare Llc | Fluid path set with turbulent mixing chamber, backflow compensator |
| US9173998B2 (en) | 2013-03-14 | 2015-11-03 | Tandem Diabetes Care, Inc. | System and method for detecting occlusions in an infusion pump |
| KR20140142920A (ko) * | 2013-06-05 | 2014-12-15 | 이근호 | 양막 삽입장치 |
| US10898638B2 (en) | 2016-03-03 | 2021-01-26 | Bayer Healthcare Llc | System and method for improved fluid delivery in multi-fluid injector systems |
| US12263326B2 (en) | 2016-11-14 | 2025-04-01 | Bayer Healthcare Llc | Methods and systems for verifying the contents of a syringe used for medical fluid delivery |
| US20180344248A1 (en) * | 2017-06-02 | 2018-12-06 | Boston Scientific Scimed, Inc. | Contrast removal system |
| EP3675931B1 (en) | 2017-08-31 | 2021-08-11 | Bayer Healthcare LLC | Injector pressure calibration system and method |
| CN110869071B (zh) | 2017-08-31 | 2023-05-02 | 拜耳医药保健有限公司 | 流体注入器系统中的动态压力控制的方法 |
| EP3676854A1 (en) | 2017-08-31 | 2020-07-08 | Bayer Healthcare LLC | Fluid path impedance assessment for improving fluid delivery performance |
| JP7252143B2 (ja) | 2017-08-31 | 2023-04-04 | バイエル・ヘルスケア・エルエルシー | 駆動部材の位置及び流体注入器システムの機械的較正のためのシステム及び方法 |
| JP7317724B2 (ja) | 2017-08-31 | 2023-07-31 | バイエル・ヘルスケア・エルエルシー | 液注入器システムの容積補償システムおよび方法 |
| AU2019256461B2 (en) | 2018-04-19 | 2024-03-07 | Bayer Healthcare Llc | System and method for air detection in fluid injector |
| WO2020046869A1 (en) | 2018-08-28 | 2020-03-05 | Bayer Healthcare Llc | Fluid injector system, method of preventing fluid backflow, and computer program product |
| AU2019332923A1 (en) | 2018-08-28 | 2021-02-11 | Bayer Healthcare Llc | Fluid injector system with improved ratio performance |
| IT201900001223A1 (it) * | 2019-01-28 | 2020-07-28 | I Vasc Srl | Manipolo di catetere, catetere e metodo |
| US10946178B1 (en) | 2020-01-07 | 2021-03-16 | Thomas J. Wool | Method for preventing contrast induced nephropathy |
| US10722638B1 (en) | 2020-01-07 | 2020-07-28 | Thomas J. Wool | Method for preventing contrast induced nephropathy |
| US11266825B2 (en) | 2020-02-20 | 2022-03-08 | First Pass, Llc | Manual clot aspiration and filtration system and method of removing a clot |
| US12311093B2 (en) | 2020-02-20 | 2025-05-27 | First Pass, Llc | Manual clot aspiration and filtration system and method of removing a clot |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US52345A (en) | 1866-01-30 | Improved composition for destroying insects | ||
| US3841331A (en) * | 1972-11-17 | 1974-10-15 | J Wilder | Suction-pump assembly for drawing body fluids |
| US4798590A (en) * | 1983-11-22 | 1989-01-17 | Medical Technology Products, Inc. | Intravenous infusion pumping system including independent pump set |
| US4689041A (en) | 1984-01-20 | 1987-08-25 | Eliot Corday | Retrograde delivery of pharmacologic and diagnostic agents via venous circulation |
| US5069662A (en) * | 1988-10-21 | 1991-12-03 | Delcath Systems, Inc. | Cancer treatment |
| US4927412A (en) | 1988-12-08 | 1990-05-22 | Retroperfusion Systems, Inc. | Coronary sinus catheter |
| US5766151A (en) * | 1991-07-16 | 1998-06-16 | Heartport, Inc. | Endovascular system for arresting the heart |
| US5324260A (en) | 1992-04-27 | 1994-06-28 | Minnesota Mining And Manufacturing Company | Retrograde coronary sinus catheter |
| US5653690A (en) | 1992-12-30 | 1997-08-05 | Medtronic, Inc. | Catheter having a balloon with retention enhancement |
| US5391199A (en) * | 1993-07-20 | 1995-02-21 | Biosense, Inc. | Apparatus and method for treating cardiac arrhythmias |
| AU685161B2 (en) | 1993-09-17 | 1998-01-15 | Edwards Lifesciences Ag | Endovascular system for arresting the heart |
| US5451207A (en) * | 1994-04-25 | 1995-09-19 | The Regents Of The University Of California | Method of coronary plaque removal with bypass and perfusion |
| US5597377A (en) | 1994-05-06 | 1997-01-28 | Trustees Of Boston University | Coronary sinus reperfusion catheter |
| US5695457A (en) * | 1994-07-28 | 1997-12-09 | Heartport, Inc. | Cardioplegia catheter system |
| DE69626105T2 (de) * | 1995-03-30 | 2003-10-23 | Heartport, Inc. | Endovaskulärerkatheter zum ableiten aus dem herz |
| DK0821566T3 (da) * | 1995-04-20 | 2004-01-26 | Acist Medical Sys Inc | Angiografisk injektor |
| WO1996040342A1 (en) | 1995-06-07 | 1996-12-19 | Cardima, Inc. | Guiding catheter for coronary sinus |
| US6017493A (en) * | 1997-09-26 | 2000-01-25 | Baxter International Inc. | Vacuum-assisted venous drainage reservoir for CPB systems |
| US6699231B1 (en) * | 1997-12-31 | 2004-03-02 | Heartport, Inc. | Methods and apparatus for perfusion of isolated tissue structure |
| WO1999033407A1 (en) * | 1997-12-31 | 1999-07-08 | Heartport, Inc. | Methods and apparatus for perfusion of isolated tissue structure |
| US6638268B2 (en) | 2000-04-07 | 2003-10-28 | Imran K. Niazi | Catheter to cannulate the coronary sinus |
| US6554819B2 (en) * | 2001-01-09 | 2003-04-29 | Mount Sinai School Of Medicine Of New York University | Method and device for preventing contrast associated nephropathy |
| US6699232B2 (en) * | 2001-03-01 | 2004-03-02 | Scimed Life Systems, Inc. | Fluid injection apparatus with improved contrast visualization |
| US20030120202A1 (en) * | 2001-12-21 | 2003-06-26 | Gordon Lucas S. | Magnetic extracorporeal circuit for removal of medical agents |
| US7163520B2 (en) * | 2002-06-26 | 2007-01-16 | Chf Solutions, Inc. | Method and device for removal of radiocontrast media from blood |
| US20040185321A1 (en) * | 2003-02-14 | 2004-09-23 | David Sutherland | Sofc with floating current collectors |
-
2002
- 2002-01-23 MX MXPA03006557A patent/MXPA03006557A/es not_active Application Discontinuation
- 2002-01-23 AU AU2002235462A patent/AU2002235462A1/en not_active Abandoned
- 2002-01-23 US US10/057,202 patent/US7363072B2/en not_active Expired - Fee Related
- 2002-01-23 IL IL15691702A patent/IL156917A0/xx unknown
- 2002-01-23 EP EP02702077A patent/EP1353721A2/en not_active Withdrawn
- 2002-01-23 WO PCT/US2002/002031 patent/WO2002058777A2/en not_active Ceased
- 2002-01-23 CA CA002434515A patent/CA2434515A1/en not_active Abandoned
- 2002-01-23 JP JP2002559107A patent/JP2005503183A/ja active Pending
-
2007
- 2007-08-20 US US11/894,328 patent/US8100849B2/en not_active Expired - Fee Related
-
2009
- 2009-03-27 US US12/413,361 patent/US7998102B2/en not_active Expired - Fee Related
-
2011
- 2011-09-06 US US13/226,302 patent/US20120022444A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20020099254A1 (en) | 2002-07-25 |
| US20120022444A1 (en) | 2012-01-26 |
| US8100849B2 (en) | 2012-01-24 |
| EP1353721A2 (en) | 2003-10-22 |
| WO2002058777A3 (en) | 2003-03-27 |
| AU2002235462A1 (en) | 2002-08-06 |
| MXPA03006557A (es) | 2003-09-22 |
| US7363072B2 (en) | 2008-04-22 |
| WO2002058777A2 (en) | 2002-08-01 |
| US7998102B2 (en) | 2011-08-16 |
| JP2005503183A (ja) | 2005-02-03 |
| US20090187101A1 (en) | 2009-07-23 |
| CA2434515A1 (en) | 2002-08-01 |
| US20080021314A1 (en) | 2008-01-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL156917A0 (en) | Method and apparatus to remove substances from vessels of the heart and other parts of the body to minimize or avoid renal or other harm or dysfunction | |
| PL364995A1 (en) | Method for the treatment or prevention of flavivirus | |
| PT1231887E (pt) | Método e composição para o tratamento de cicatrizes | |
| AP2001002284A0 (en) | Novel method of treatment | |
| HUP0302739A3 (en) | Method for the treatment of tobacco | |
| IL145875A0 (en) | Novel method of treatment | |
| KR100510795B1 (en) | Compositions and Methods for the Treatment of Tumor | |
| EP1173470A4 (en) | TREATMENT OF BONE DISORDERS BASED ON ADRENOMEDULLINE OR ADRENOMEDULLINE AGONISTS | |
| EP1187604A4 (en) | CONNECTIONS AND METHODS FOR TREATING POST-TRAUMATIC STRESS FAILURES | |
| HUP0200738A3 (en) | Method of the treatment of incontinence | |
| AU1794801A (en) | Method for treatment and prevention of physiological shock | |
| PL353282A1 (en) | Method for removing skin from the body and/or parts of the body of animals, and device therefor | |
| AU2001255730A1 (en) | Methods and compositions for the treatment of cardiac indications | |
| GB0025103D0 (en) | Treatment of process fluids | |
| AU1646201A (en) | Pharmaceutical agent for the treatment of cachexia and/or cardiogenic shock | |
| HU0203719D0 (en) | Polyuretan composition for fillin blood vessels and method of aplication of it | |
| EP1402902A4 (en) | VASCULAR REGENERATION THERAPY | |
| GB9930688D0 (en) | Novel method of treatment | |
| HUP0300043A3 (en) | Method and composition for the treatment of pain | |
| GB0027001D0 (en) | Method and apparatus for the treatment of sludge | |
| IL150208A0 (en) | Compound and method for the treatment of pain | |
| IL132664A (en) | Method for sterilization and for the prevention of outcrop of catha edulis forsk | |
| KR100511819B1 (en) | Compositions and Methods for the Treatment of Tumor | |
| GB9902371D0 (en) | Apparatus and methods relating to the cleaning of storage vessels | |
| GB9930696D0 (en) | Novel method of treatment |