IL156536A0 - Pyrazolo [3,4-d] pyrimidin-4-one derivatives and pharmaceutical compositions containing the same - Google Patents

Pyrazolo [3,4-d] pyrimidin-4-one derivatives and pharmaceutical compositions containing the same

Info

Publication number
IL156536A0
IL156536A0 IL15653602A IL15653602A IL156536A0 IL 156536 A0 IL156536 A0 IL 156536A0 IL 15653602 A IL15653602 A IL 15653602A IL 15653602 A IL15653602 A IL 15653602A IL 156536 A0 IL156536 A0 IL 156536A0
Authority
IL
Israel
Prior art keywords
pyrazolo
pyrimidin
derivatives
same
pharmaceutical compositions
Prior art date
Application number
IL15653602A
Other languages
English (en)
Original Assignee
Bristol Myers Squibb Pharma Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Pharma Co filed Critical Bristol Myers Squibb Pharma Co
Publication of IL156536A0 publication Critical patent/IL156536A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL15653602A 2001-02-27 2002-02-27 Pyrazolo [3,4-d] pyrimidin-4-one derivatives and pharmaceutical compositions containing the same IL156536A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/794,825 US6559152B2 (en) 1998-10-13 2001-02-27 6-substituted pyrazolo[3,4-d]pyrimidin-4-ones useful as cyclin dependent kinase inhibitors
PCT/US2002/006002 WO2002067654A2 (fr) 2001-02-27 2002-02-27 Pyrazolo[3,4-d]pyrimidine-4-ones 6-substitutes utiles en tant qu'inhibiteurs de la kinase dependante des cyclines

Publications (1)

Publication Number Publication Date
IL156536A0 true IL156536A0 (en) 2004-01-04

Family

ID=25163791

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15653602A IL156536A0 (en) 2001-02-27 2002-02-27 Pyrazolo [3,4-d] pyrimidin-4-one derivatives and pharmaceutical compositions containing the same

Country Status (6)

Country Link
US (1) US6559152B2 (fr)
EP (1) EP1383769A4 (fr)
JP (1) JP2004520407A (fr)
CA (1) CA2431038A1 (fr)
IL (1) IL156536A0 (fr)
WO (1) WO2002067654A2 (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7605175B2 (en) 2001-03-02 2009-10-20 Gpc Biotech Ag Inhibitors of cyclin-dependent kinases, compositions and uses related thereto
US20040248905A1 (en) * 2001-07-10 2004-12-09 Markwalder Jay A 6-Substituted pyrazolo [3,4-d] pyrimidin-4-ones useful as cyclin dependent kinase inhibitors
UA81453C2 (en) * 2003-02-27 2008-01-10 Pyrazolopyridine derivates
CA2521854C (fr) 2003-04-07 2011-11-01 Gpc Biotech, Inc. Inhibiteurs de kinases dependant des cyclines, compositions et utilisations associees
AU2004309415B2 (en) 2003-12-23 2010-08-26 Agennix Usa Inc. Inhibitors of cyclin-dependent kinases, compositions and uses related thereto
AR050188A1 (es) * 2004-08-03 2006-10-04 Uriach Y Compania S A J Compuestos heterociclicos condensados utiles en terapia como inhibidores de quinasas p38 y composiciones farmaceuticas que los contienen
MX2009009552A (es) * 2007-03-07 2009-09-28 Alantos Pharm Holding Inhibidores de metaloproteasa que contienen una porcion heterociclica.
EP2019101A1 (fr) * 2007-07-26 2009-01-28 GPC Biotech AG Pyrazol[3,4-d]pyrimidin-4-one utile en tant que Inhibiteur de kinase
JP5771750B2 (ja) * 2011-10-28 2015-09-02 チョン クン ダン ファーマシューティカル コーポレーション Ｈｄａｃ阻害剤用のヒドロキサメート誘導体およびこれを含む薬学的組成物
BR112018009879A2 (pt) 2015-11-18 2018-11-13 Genzyme Corp biomarcador da doença renal policística e seus usos
AU2017368286B2 (en) * 2016-11-30 2021-12-16 Medizinische Universität Innsbruck 3-amino-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-ones as cyclin dependent kinase inhibitors
US11066404B2 (en) 2018-10-11 2021-07-20 Incyte Corporation Dihydropyrido[2,3-d]pyrimidinone compounds as CDK2 inhibitors
WO2020168197A1 (fr) 2019-02-15 2020-08-20 Incyte Corporation Composés de pyrrolo[2,3-d]pyrimidinone en tant qu'inhibiteurs de cdk2
TW202100520A (zh) 2019-03-05 2021-01-01 美商英塞特公司 作為cdk2 抑制劑之吡唑基嘧啶基胺化合物
US11919904B2 (en) 2019-03-29 2024-03-05 Incyte Corporation Sulfonylamide compounds as CDK2 inhibitors
US11440914B2 (en) 2019-05-01 2022-09-13 Incyte Corporation Tricyclic amine compounds as CDK2 inhibitors
WO2020223558A1 (fr) 2019-05-01 2020-11-05 Incyte Corporation Composés aminés tricycliques en tant qu'inhibiteurs de cdk2
EP4013750A1 (fr) 2019-08-14 2022-06-22 Incyte Corporation Composés imidazolyl-pyrimidinylamines utilisés comme inhibiteurs de la cdk2
WO2021072232A1 (fr) 2019-10-11 2021-04-15 Incyte Corporation Amines bicycliques utilisées en tant qu'inhibiteurs de cdk2
US11981671B2 (en) 2021-06-21 2024-05-14 Incyte Corporation Bicyclic pyrazolyl amines as CDK2 inhibitors
US11976073B2 (en) 2021-12-10 2024-05-07 Incyte Corporation Bicyclic amines as CDK2 inhibitors

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3211732A (en) 1965-10-12 Pyrazolob:x-d]pyrlil/hdines
CH398626A (de) * 1960-05-11 1966-03-15 Ciba Geigy Verfahren zur Herstellung neuer Pyrazolopyrimidine
TW444018B (en) 1992-12-17 2001-07-01 Pfizer Pyrazolopyrimidines
US5593997A (en) 1995-05-23 1997-01-14 Pfizer Inc. 4-aminopyrazolo(3-,4-D)pyrimidine and 4-aminopyrazolo-(3,4-D)pyridine tyrosine kinase inhibitors
US6403599B1 (en) 1995-11-08 2002-06-11 Pfizer Inc Corticotropin releasing factor antagonists
US5866702A (en) 1996-08-02 1999-02-02 Cv Therapeutics, Incorporation Purine inhibitors of cyclin dependent kinase 2
US6531477B1 (en) 1998-10-13 2003-03-11 Dupont Pharmaceuticals Company 6-substituted pyrazolo [3,4-d] pyrimidin-4-ones useful as cyclin dependent kinase inhibitors
US20040248905A1 (en) * 2001-07-10 2004-12-09 Markwalder Jay A 6-Substituted pyrazolo [3,4-d] pyrimidin-4-ones useful as cyclin dependent kinase inhibitors
JP2005511535A (ja) * 2001-10-15 2005-04-28 ジーピーシー バイオテック インク． サイクリン依存性キナーゼの阻害剤、組成物及びその使用

Also Published As

Publication number Publication date
WO2002067654A2 (fr) 2002-09-06
US6559152B2 (en) 2003-05-06
WO2002067654A3 (fr) 2002-10-31
JP2004520407A (ja) 2004-07-08
EP1383769A2 (fr) 2004-01-28
US20020013328A1 (en) 2002-01-31
CA2431038A1 (fr) 2002-09-06
EP1383769A4 (fr) 2005-08-03

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