IL154769A0 - Cardiac arrhythmia treatment methods - Google Patents

Cardiac arrhythmia treatment methods

Info

Publication number
IL154769A0
IL154769A0 IL15476901A IL15476901A IL154769A0 IL 154769 A0 IL154769 A0 IL 154769A0 IL 15476901 A IL15476901 A IL 15476901A IL 15476901 A IL15476901 A IL 15476901A IL 154769 A0 IL154769 A0 IL 154769A0
Authority
IL
Israel
Prior art keywords
treatment methods
cardiac arrhythmia
arrhythmia treatment
cardiac
methods
Prior art date
Application number
IL15476901A
Other languages
English (en)
Original Assignee
Univ Johns Hopkins
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Johns Hopkins filed Critical Univ Johns Hopkins
Publication of IL154769A0 publication Critical patent/IL154769A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1858Platelet-derived growth factor [PDGF]
    • A61K38/1866Vascular endothelial growth factor [VEGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0067Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0082Catheter tip comprising a tool
    • A61M25/0084Catheter tip comprising a tool being one or more injection needles
    • A61M2025/0089Single injection needle protruding axially, i.e. along the longitudinal axis of the catheter, from the distal tip
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/12Blood circulatory system
    • A61M2210/125Heart

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Vascular Medicine (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL15476901A 2000-09-06 2001-09-06 Cardiac arrhythmia treatment methods IL154769A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23031100P 2000-09-06 2000-09-06
US29588901P 2001-06-05 2001-06-05
PCT/US2001/027623 WO2002019966A2 (en) 2000-09-06 2001-09-06 Cardiac arrhythmia treatment methods

Publications (1)

Publication Number Publication Date
IL154769A0 true IL154769A0 (en) 2003-10-31

Family

ID=26924110

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15476901A IL154769A0 (en) 2000-09-06 2001-09-06 Cardiac arrhythmia treatment methods

Country Status (7)

Country Link
US (6) US7034008B2 (https=)
EP (2) EP2363152A1 (https=)
JP (1) JP5106738B2 (https=)
AU (2) AU8880701A (https=)
CA (1) CA2421584C (https=)
IL (1) IL154769A0 (https=)
WO (1) WO2002019966A2 (https=)

Families Citing this family (105)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0928135B1 (en) * 1996-07-17 2006-06-14 Medtronic, Inc. System for enhancing cardiac signal sensing by cardiac pacemakers through genetic treatment
WO2002087419A2 (en) * 2001-04-27 2002-11-07 Johns Hopkins University Biological pacemaker
WO2002019966A2 (en) * 2000-09-06 2002-03-14 Johns Hopkins University Cardiac arrhythmia treatment methods
US20090175790A1 (en) * 2000-09-06 2009-07-09 The Johns Hopkins University Cardiac arrhythmia treatment methods and biological pacemaker
US7294333B1 (en) * 2000-10-20 2007-11-13 Genegrafts Ltd. Nucleic acid constructs and cells, and methods utilizing same for modifying the electrophysiological function of excitable tissues
US7699790B2 (en) 2000-12-20 2010-04-20 Ev3, Inc. Debulking catheters and methods
US7927784B2 (en) 2000-12-20 2011-04-19 Ev3 Vascular lumen debulking catheters and methods
WO2002098287A2 (en) * 2001-06-06 2002-12-12 The Trustees Of Columbia University In The City Of New York A high throughput biological heart rate monitor that is molecularly determined
US6849611B2 (en) * 2001-06-06 2005-02-01 The Trustees Of Columbia University In The City Of New York Implantation of biological pacemaker that is molecularly determined
US6783979B2 (en) * 2001-06-06 2004-08-31 The Trustees Of Columbia University In The City Of New York Research Foundation Of State University Of New York Vectors encoding HCN channels and MiRP1
CN1612691A (zh) 2001-11-08 2005-05-04 加利福尼亚大学董事会 纠正心脏传导障碍的方法和组合物
US6743797B2 (en) * 2002-02-22 2004-06-01 Chantest, Inc. Methods for treating cardiac arrhythmia
US6811777B2 (en) 2002-04-13 2004-11-02 Allan Mishra Compositions and minimally invasive methods for treating incomplete connective tissue repair
WO2003095016A1 (en) * 2002-05-08 2003-11-20 The Regents Of The University Of California System and method for forming a non-ablative cardiac conduction block
US8003618B2 (en) * 2002-10-02 2011-08-23 The John Hopkins University Focal calcium channel modulation
US7627373B2 (en) 2002-11-30 2009-12-01 Cardiac Pacemakers, Inc. Method and apparatus for cell and electrical therapy of living tissue
WO2004078065A2 (en) 2003-03-03 2004-09-16 Sinus Rhythm Technologies, Inc. Electrical conduction block implant device
US20070021375A1 (en) 2003-04-25 2007-01-25 Vinod Sharma Genetic modification of targeted regions of the cardiac conduction system
US8013133B2 (en) * 2003-04-25 2011-09-06 Medtronic, Inc. Genetic modification of targeted regions of the cardiac conduction system
US20050021089A1 (en) * 2003-07-24 2005-01-27 Medtronic, Inc. Compositions and methods for treating cardiac dysfunction
ITRM20030376A1 (it) * 2003-07-31 2005-02-01 Univ Roma Procedimento per l'isolamento e l'espansione di cellule staminali cardiache da biopsia.
JP2007520259A (ja) * 2003-11-10 2007-07-26 シンフォニー メディカル, インコーポレイテッド 心房細動患者における心室速度を制御するための方法
SE526861C2 (sv) 2003-11-17 2005-11-15 Syntach Ag Vävnadslesionsskapande anordning samt en uppsättning av anordningar för behandling av störningar i hjärtrytmregleringssystemet
WO2005047500A1 (ja) * 2003-11-17 2005-05-26 Eisai Co., Ltd. hERGチャネル発現細胞
WO2005062857A2 (en) * 2003-12-24 2005-07-14 The Trustees Of Columbia University In The City Of New York Creation of a biological atrioventricular bypass to compensate for atrioventricular block
US20060128647A1 (en) * 2003-12-24 2006-06-15 Daniel Sigg Novel oligonucleotides and treating cardiac disorders by using the same
US8859273B2 (en) * 2003-12-24 2014-10-14 Medtronic, Inc. Methods of using HCN genes to treat cardiac arrhythmias
WO2005082424A1 (en) * 2004-02-26 2005-09-09 Merck & Co., Inc. Biological assay
US7840263B2 (en) * 2004-02-27 2010-11-23 Cardiac Pacemakers, Inc. Method and apparatus for device controlled gene expression
US9398967B2 (en) 2004-03-02 2016-07-26 Syntach Ag Electrical conduction block implant device
US7764995B2 (en) 2004-06-07 2010-07-27 Cardiac Pacemakers, Inc. Method and apparatus to modulate cellular regeneration post myocardial infarct
US7729761B2 (en) 2004-07-14 2010-06-01 Cardiac Pacemakers, Inc. Method and apparatus for controlled gene or protein delivery
EP1781371A4 (en) * 2004-07-19 2007-12-19 Univ Columbia ASSAY SYSTEM FOR MONITORING THE EFFECTS OF GENETICALLY MANUFACTURED CELLS TO CHANGE THE FUNCTION OF A SYNCYTIUM
EP1829526B1 (en) * 2004-11-02 2016-01-20 National University Corporation Tokyo Medical and Dental University Liposome and method of injecting substance into cell by using the same
US11660317B2 (en) 2004-11-08 2023-05-30 The Johns Hopkins University Compositions comprising cardiosphere-derived cells for use in cell therapy
US8060219B2 (en) 2004-12-20 2011-11-15 Cardiac Pacemakers, Inc. Epicardial patch including isolated extracellular matrix with pacing electrodes
US7981065B2 (en) 2004-12-20 2011-07-19 Cardiac Pacemakers, Inc. Lead electrode incorporating extracellular matrix
WO2006084322A1 (en) * 2005-02-09 2006-08-17 Craig Steven Mclachlan Treatment method for modifying tissue passive electrical conductance
US8565898B2 (en) * 2005-04-28 2013-10-22 Medtronic, Inc. Rate control during AF using cellular intervention to modulate AV node
EP1917350A4 (en) * 2005-07-29 2009-04-22 Univ Columbia BIOLOGICAL BYPASS BRIDGE WITH SODIUM CHANNELS, CALCIUM CHANNELS AND / OR KALIUM CHANNELS FOR COMPENSATING A LEAD BLOCK IN THE HEART
US7774057B2 (en) 2005-09-06 2010-08-10 Cardiac Pacemakers, Inc. Method and apparatus for device controlled gene expression for cardiac protection
EP1942946A4 (en) * 2005-10-14 2009-11-25 Univ Johns Hopkins BIOLOGICALLY AVAILABLE CELLS
US20070190028A1 (en) * 2006-02-13 2007-08-16 Jihong Qu Method and apparatus for heat or electromagnetic control of gene expression
US7989207B2 (en) 2006-02-17 2011-08-02 Tyco Healthcare Group Lp Testing lumenectomy samples for markers of non-vascular diseases
GB2437893A (en) * 2006-07-25 2007-11-07 Celladon Corp Extended antegrade epicardial coronary infusion of adeno-associated viral vectors for gene therapy
US20080082415A1 (en) * 2006-09-20 2008-04-03 Vishwanath Shastry Listing generation and advertising management utilizing catalog information
US8825677B2 (en) 2006-09-20 2014-09-02 Ebay Inc. Listing generation utilizing catalog information
WO2008079412A2 (en) * 2006-12-22 2008-07-03 The Trustees Of Columbia University In The City Of New York Methods and compositions to treat arrhythmias
US20100150887A1 (en) * 2007-01-25 2010-06-17 Duff Henry J Tissue Progenitor Cells That Overexpress ERG
US20090047703A1 (en) * 2007-08-17 2009-02-19 University Of Maryland, Baltimore ERG-1 Peptides and Polynucleotides and Their Use in the Treatment and Diagnosis of Disease
US8311620B2 (en) * 2007-08-22 2012-11-13 Cardiac Pacemakers, Inc. Methods and apparatus to treat and prevent atrial tachyarrhythmias
US20090054828A1 (en) * 2007-08-22 2009-02-26 Cardiac Pacemakers, Inc. Systems for transient conduction control
WO2009036220A2 (en) 2007-09-12 2009-03-19 The Regents Of The University Of California Compositions and methods for improving the functional efficacy of stem cell-derived cardiomyocytes
US20090233991A1 (en) * 2007-11-01 2009-09-17 Hee Cheol Cho Generation of biological pacemaker activity
WO2009105135A1 (en) 2008-02-19 2009-08-27 Celladon Corporation Compositions for enhanced uptake of viral vectors in the myocardium
US20110256112A2 (en) * 2008-03-07 2011-10-20 The Trustees Of Columbia University In The City Of New York Compensating for Atrioventricular Block Using a Nucleic Acid Encoding a Sodium Channel or Gap Junction Protein
WO2009120082A2 (en) * 2008-03-27 2009-10-01 Academisch Medisch Centrum Bij De Universiteit Van Amsterdam Means and methods for influencing electrical activity of cells
WO2010042658A1 (en) 2008-10-07 2010-04-15 Bioparadox, Llc Use of platelet rich plasma composition in the treatment of cardiac conduction abnormalities
EP2493547A4 (en) * 2009-10-27 2013-06-19 Cedars Sinai Medical Center EXTERNAL MAGNETIC POWER FOR TARGETED CELL RELIEF WITH REINFORCED CELL RESERVATION
US9393198B2 (en) * 2010-03-22 2016-07-19 Signpath Pharma Inc. Intravenous curcumin and derivatives for treatment of neurodegenerative and stress disorders
US9249392B2 (en) 2010-04-30 2016-02-02 Cedars-Sinai Medical Center Methods and compositions for maintaining genomic stability in cultured stem cells
US9845457B2 (en) 2010-04-30 2017-12-19 Cedars-Sinai Medical Center Maintenance of genomic stability in cultured stem cells
US9744132B2 (en) 2010-10-29 2017-08-29 Infirst Healthcare Limited Solid solution compositions and use in chronic inflammation
US10695432B2 (en) * 2010-10-29 2020-06-30 Infirst Healthcare Limited Solid solution compositions and use in severe pain
US9271950B2 (en) 2010-10-29 2016-03-01 Infirst Healthcare Limited Compositions for treating chronic inflammation and inflammatory diseases
US9308213B2 (en) 2010-10-29 2016-04-12 Infirst Healthcare Limited Solid solution compositions and use in chronic inflammation
US11730709B2 (en) 2010-10-29 2023-08-22 Infirst Healthcare Limited Compositions and methods for treating severe pain
US11202831B2 (en) 2010-10-29 2021-12-21 Infirst Healthcare Limited Solid solution compositions and use in cardiovascular disease
US10695431B2 (en) 2010-10-29 2020-06-30 Infirst Healthcare Limited Solid solution compositions and use in cardiovascular disease
US8895537B2 (en) 2010-10-29 2014-11-25 Infirst Healthcare Ltd. Compositions and methods for treating cardiovascular diseases
US11224659B2 (en) 2010-10-29 2022-01-18 Infirst Healthcare Limited Solid solution compositions and use in severe pain
US9504664B2 (en) 2010-10-29 2016-11-29 Infirst Healthcare Limited Compositions and methods for treating severe pain
US8639323B2 (en) 2010-11-01 2014-01-28 Medtronic, Inc. System and apparatus to monitor biopacemaker maturation
WO2012068385A2 (en) 2010-11-18 2012-05-24 Medtronic, Inc. Implantable medical device with swappable headers
US9592398B2 (en) 2011-05-12 2017-03-14 Medtronic, Inc. Leadless implantable medical device with osmotic pump
US10532045B2 (en) 2013-12-18 2020-01-14 Signpath Pharma, Inc. Liposomal mitigation of drug-induced inhibition of the cardiac IKr channel
US10449193B2 (en) 2011-06-03 2019-10-22 Signpath Pharma Inc. Protective effect of DMPC, DMPG, DMPC/DMPG, lysoPG and lysoPC against drugs that cause channelopathies
EP3326616B1 (en) 2011-06-03 2021-07-28 Signpath Pharma Inc. Liposomal mitigation of drug-induced long qt syndrome and potassium delayed-rectifier current
US12004868B2 (en) 2011-06-03 2024-06-11 Signpath Pharma Inc. Liposomal mitigation of drug-induced inhibition of the cardiac IKr channel
US10349884B2 (en) 2011-06-03 2019-07-16 Sighpath Pharma Inc. Liposomal mitigation of drug-induced inhibition of the cardiac ikr channel
US8753674B2 (en) 2011-06-03 2014-06-17 Signpath Pharma Inc. Liposomal mitigation of drug-induced long QT syndrome and potassium delayed-rectifier current
US10238602B2 (en) 2011-06-03 2019-03-26 Signpath Pharma, Inc. Protective effect of DMPC, DMPG, DMPC/DMPG, LysoPG and LysoPC against drugs that cause channelopathies
US10117881B2 (en) 2011-06-03 2018-11-06 Signpath Pharma, Inc. Protective effect of DMPC, DMPG, DMPC/DMPG, LYSOPG and LYSOPC against drugs that cause channelopathies
US9681836B2 (en) 2012-04-23 2017-06-20 Cyberonics, Inc. Methods, systems and apparatuses for detecting seizure and non-seizure states
US9884076B2 (en) 2012-06-05 2018-02-06 Capricor, Inc. Optimized methods for generation of cardiac stem cells from cardiac tissue and their use in cardiac therapy
EP3563859B1 (en) 2012-08-13 2021-10-13 Cedars-Sinai Medical Center Cardiosphere-derived exosomes for tissue regeneration
CA2882978A1 (en) 2012-08-31 2014-03-06 Signpath Pharma Inc. Curcumin-er, a liposomal-plga sustained release nanocurcumin for minimizing qt prolongation for cancer therapy
GB201309882D0 (en) * 2013-06-03 2013-07-17 Isis Innovation Prevention and treatment of atrial fibrillation
US20140356893A1 (en) 2013-06-04 2014-12-04 Allan Mishra Compositions and methods for using platelet-rich plasma for drug discovery, cell nuclear reprogramming, proliferation or differentiation
US10087436B2 (en) 2014-02-06 2018-10-02 The Regents Of The University Of California Electrophysiologically mature cardiomyocytes and methods for making same
AU2015269699B2 (en) 2014-06-03 2020-08-13 Avanti Polar Lipids, Inc. Protective effect of DMPC, DMPG, DMPC/DMPG, EGPG, LysoPG and LysoPC against drugs that cause channelopathies
EP4494699A3 (en) 2014-10-03 2025-04-30 Cedars-Sinai Medical Center Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of muscular dystrophy
EP3206702A1 (en) * 2014-10-16 2017-08-23 Academisch Medisch Centrum Nk3 agonist for use in the treatment of a patient suffering from atrial arrhythmia or fibrillation
WO2017123662A1 (en) 2016-01-11 2017-07-20 Cedars-Sinai Medical Center Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of heart failure with preserved ejection fraction
AU2017257496B2 (en) 2016-04-27 2020-05-07 Signpath Pharma, Inc. Prevention of drug-induced atrio-ventricular block
WO2017210652A1 (en) 2016-06-03 2017-12-07 Cedars-Sinai Medical Center Cdc-derived exosomes for treatment of ventricular tachyarrythmias
US11541078B2 (en) 2016-09-20 2023-01-03 Cedars-Sinai Medical Center Cardiosphere-derived cells and their extracellular vesicles to retard or reverse aging and age-related disorders
JP7336769B2 (ja) 2017-04-19 2023-09-01 シーダーズ―シナイ メディカル センター 骨格筋ジストロフィーを治療する方法及び組成物
US12098385B2 (en) 2017-09-20 2024-09-24 The Regents Of The University Of California Gene therapy strategy to restore cardiac electrical and structural function in arrhythmogenic right ventricular cardiomyopathy
ES2976559T3 (es) 2017-09-20 2024-08-05 Univ California Terapia génica con conexina 43 para restaurar la función eléctrica y cardíaca y la estructura cardíaca, en la miocardiopatía arritmogénica del ventrículo derecho
KR20240145085A (ko) 2017-10-19 2024-10-04 사인패스 파마 인코포레이티드 채널병증을 야기하는 약물에 대한 DMPC, DMPG, DMPC/DMPG, LysoPG 및 LysoPC의 보호 효과
WO2019126068A1 (en) 2017-12-20 2019-06-27 Cedars-Sinai Medical Center Engineered extracellular vesicles for enhanced tissue delivery
EP3749344A4 (en) 2018-02-05 2022-01-26 Cedars-Sinai Medical Center METHODS OF THERAPEUTIC USE OF EXOSOMES AND Y-RNAS
WO2020206103A1 (en) * 2019-04-04 2020-10-08 University Of Massachusetts Ventricular arrhythmias and related methods
CN117024557B (zh) * 2023-10-10 2024-01-30 天津外泌体科技有限公司 14-3-3蛋白theta异构体作为细胞外囊泡支架蛋白的应用和细胞外囊泡

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5401629A (en) 1990-08-07 1995-03-28 The Salk Institute Biotechnology/Industrial Associates, Inc. Assay methods and compositions useful for measuring the transduction of an intracellular signal
US5163950A (en) * 1990-08-24 1992-11-17 Medical Engineering Corporation Balloon catheter and endoscope kit
EP0745134A1 (en) 1994-02-22 1996-12-04 Danafarber Cancer Institute Nucleic acid delivery system, method of synthesis and uses thereof
US5662585A (en) * 1994-05-05 1997-09-02 Imagyn Medical, Inc. Endoscope with protruding member and method of utilizing the same
US5836905A (en) * 1994-06-20 1998-11-17 Lemelson; Jerome H. Apparatus and methods for gene therapy
US5824550A (en) * 1994-10-28 1998-10-20 Barnes-Jewish Hopital Voltage-gated calcium channel and antisense oligonucleotides thereto
WO1996028537A1 (en) 1995-03-09 1996-09-19 University Of Utah Research Foundation Long qt genes and method for diagnosing or preventing the occurrence of long qt syndrome
US6605274B1 (en) * 1995-04-11 2003-08-12 The Regents Of The University Of California Method for in vivo regulation of cardiac muscle contractility
DK0876491T3 (da) * 1995-12-22 2009-07-06 Univ Utah Res Found Langt QT-syndrom-gen, der koder for KVLQT1 og dets association med minK
US5944710A (en) * 1996-06-24 1999-08-31 Genetronics, Inc. Electroporation-mediated intravascular delivery
AU734576B2 (en) * 1996-08-02 2001-06-14 Elan Pharmaceuticals, Inc. Voltage-gated calcium channel antagonist and methods
US20020009772A1 (en) * 1997-02-28 2002-01-24 Terry P. Snutch Novel human calcium channels and related probes, cell lines and mehtods
US6086582A (en) * 1997-03-13 2000-07-11 Altman; Peter A. Cardiac drug delivery system
US6123699A (en) * 1997-09-05 2000-09-26 Cordis Webster, Inc. Omni-directional steerable catheter
US6183444B1 (en) * 1998-05-16 2001-02-06 Microheart, Inc. Drug delivery module
AU1520599A (en) 1997-11-07 1999-05-31 Johns Hopkins University, The Somatic transfer of modified genes to predict drug effects
US6703485B2 (en) * 1997-12-23 2004-03-09 The Trustees Of Columbia University In The City Of New York Brain and heart cyclic nucleotide gated ion channel compounds and uses thereof
US6776987B1 (en) * 1998-01-13 2004-08-17 Massachusetts Institute Of Technology Enhancement of cardiac chronotropy
US5965396A (en) * 1998-01-13 1999-10-12 Zeneca Limited Human lymph node derived GTPase
US6207422B1 (en) * 1998-04-17 2001-03-27 The Metrohealth System Protein that enhances expression of potassium channels on cell surfaces and nucleic acids that encode the same
US6623474B1 (en) * 1998-06-04 2003-09-23 Biosense Webster, Inc. Injection catheter with needle stop
US6365337B1 (en) * 1998-07-27 2002-04-02 University Of Iowa Research Foundation Genes encoding neuronal voltage-gated calcium channel gamma subunits
WO2000018903A2 (en) * 1998-09-29 2000-04-06 The Johns Hopkins University Inducible genetic suppression of cellular excitability
EP1139751A4 (en) * 1998-12-28 2003-03-19 Arch Dev Corp EFFICIENT AND STABLE -I (IN VIVO) GENE TRANSFER TO CARDIOMYCETS USING RECOMBINANT ADENO-ASSOCIATED VIRUS VECTORS
AU2732000A (en) 1999-01-19 2000-08-01 Children's Hospital Of Philadelphia, The Reverse gene therapy
WO2002019966A2 (en) * 2000-09-06 2002-03-14 Johns Hopkins University Cardiac arrhythmia treatment methods
WO2002087419A2 (en) * 2001-04-27 2002-11-07 Johns Hopkins University Biological pacemaker
US6992070B2 (en) * 2000-10-13 2006-01-31 The Johns Hopkins University Methods and compositions for nucleic acid delivery
US7294333B1 (en) * 2000-10-20 2007-11-13 Genegrafts Ltd. Nucleic acid constructs and cells, and methods utilizing same for modifying the electrophysiological function of excitable tissues
WO2002098287A2 (en) * 2001-06-06 2002-12-12 The Trustees Of Columbia University In The City Of New York A high throughput biological heart rate monitor that is molecularly determined
US6783979B2 (en) * 2001-06-06 2004-08-31 The Trustees Of Columbia University In The City Of New York Research Foundation Of State University Of New York Vectors encoding HCN channels and MiRP1
US8003618B2 (en) * 2002-10-02 2011-08-23 The John Hopkins University Focal calcium channel modulation
CA2526841A1 (en) * 2003-05-28 2005-04-14 Synta Pharmaceuticals Corp. Novel calcium channels and uses thereof
CN101090632A (zh) * 2004-08-02 2007-12-19 约翰·霍普金斯大学 利用新颖工程方法调节生物电性节律
US9116846B2 (en) 2013-06-10 2015-08-25 Veeam Software Ag Virtual machine backup from storage snapshot

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US20150183842A1 (en) 2015-07-02
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US7034008B2 (en) 2006-04-25
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WO2002019966A2 (en) 2002-03-14
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US20070048284A1 (en) 2007-03-01
US20040266717A1 (en) 2004-12-30
EP1324780A4 (en) 2005-06-22
JP5106738B2 (ja) 2012-12-26
US20040266716A1 (en) 2004-12-30
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US20050107323A1 (en) 2005-05-19
CA2421584A1 (en) 2002-03-14

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