AU8880701A - Cardiac arrhythmia treatment methods - Google Patents

Cardiac arrhythmia treatment methods

Info

Publication number
AU8880701A
AU8880701A AU8880701A AU8880701A AU8880701A AU 8880701 A AU8880701 A AU 8880701A AU 8880701 A AU8880701 A AU 8880701A AU 8880701 A AU8880701 A AU 8880701A AU 8880701 A AU8880701 A AU 8880701A
Authority
AU
Australia
Prior art keywords
treatment methods
cardiac arrhythmia
arrhythmia treatment
cardiac
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU8880701A
Other languages
English (en)
Inventor
J Kevin Donahue
Eduardo Marban
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Johns Hopkins University
Original Assignee
Johns Hopkins University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johns Hopkins University filed Critical Johns Hopkins University
Publication of AU8880701A publication Critical patent/AU8880701A/xx
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1858—Platelet-derived growth factor [PDGF]
    • A61K38/1866—Vascular endothelial growth factor [VEGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0082—Catheter tip comprising a tool
    • A61M25/0084—Catheter tip comprising a tool being one or more injection needles
    • A61M2025/0089—Single injection needle protruding axially, i.e. along the longitudinal axis of the catheter, from the distal tip
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/12—Blood circulatory system
    • A61M2210/125—Heart

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Vascular Medicine (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU8880701A 2000-09-06 2001-09-06 Cardiac arrhythmia treatment methods Pending AU8880701A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23031100P 2000-09-06 2000-09-06
US29588901P 2001-06-05 2001-06-05
PCT/US2001/027623 WO2002019966A2 (en) 2000-09-06 2001-09-06 Cardiac arrhythmia treatment methods

Publications (1)

Publication Number Publication Date
AU8880701A true AU8880701A (en) 2002-03-22

Family

ID=26924110

Family Applications (2)

Application Number Title Priority Date Filing Date
AU8880701A Pending AU8880701A (en) 2000-09-06 2001-09-06 Cardiac arrhythmia treatment methods
AU2001288807A Ceased AU2001288807B2 (en) 2000-09-06 2001-09-06 Cardiac arrhythmia treatment methods

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2001288807A Ceased AU2001288807B2 (en) 2000-09-06 2001-09-06 Cardiac arrhythmia treatment methods

Country Status (7)

Country Link
US (6) US7034008B2 (https=)
EP (2) EP1324780A4 (https=)
JP (1) JP5106738B2 (https=)
AU (2) AU8880701A (https=)
CA (1) CA2421584C (https=)
IL (1) IL154769A0 (https=)
WO (1) WO2002019966A2 (https=)

Families Citing this family (105)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998002040A1 (en) * 1996-07-17 1998-01-22 Medtronic, Inc. System for enhancing cardiac signal sensing by cardiac pacemakers through genetic treatment
EP1324780A4 (en) * 2000-09-06 2005-06-22 Univ Johns Hopkins METHODS OF TREATING CARDIAC ARRHYTHMIA
US20090175790A1 (en) * 2000-09-06 2009-07-09 The Johns Hopkins University Cardiac arrhythmia treatment methods and biological pacemaker
US20040254134A1 (en) * 2001-04-27 2004-12-16 Eduardo Marban Biological pacemaker
US7294333B1 (en) * 2000-10-20 2007-11-13 Genegrafts Ltd. Nucleic acid constructs and cells, and methods utilizing same for modifying the electrophysiological function of excitable tissues
US7699790B2 (en) 2000-12-20 2010-04-20 Ev3, Inc. Debulking catheters and methods
US7927784B2 (en) 2000-12-20 2011-04-19 Ev3 Vascular lumen debulking catheters and methods
WO2002098287A2 (en) * 2001-06-06 2002-12-12 The Trustees Of Columbia University In The City Of New York A high throughput biological heart rate monitor that is molecularly determined
US6849611B2 (en) * 2001-06-06 2005-02-01 The Trustees Of Columbia University In The City Of New York Implantation of biological pacemaker that is molecularly determined
US6783979B2 (en) 2001-06-06 2004-08-31 The Trustees Of Columbia University In The City Of New York Research Foundation Of State University Of New York Vectors encoding HCN channels and MiRP1
IL161862A0 (en) 2001-11-08 2005-11-20 Univ California Methods and compositions for correction of cardiac conduction disturbances
US6743797B2 (en) * 2002-02-22 2004-06-01 Chantest, Inc. Methods for treating cardiac arrhythmia
US6811777B2 (en) 2002-04-13 2004-11-02 Allan Mishra Compositions and minimally invasive methods for treating incomplete connective tissue repair
CN1649641A (zh) * 2002-05-08 2005-08-03 加利福尼亚大学董事会 形成非切除性心脏传导阻滞的系统和方法
AU2003299204A1 (en) * 2002-10-02 2004-04-23 The Johns Hopkins University Focal calcium channel modulation
US7627373B2 (en) 2002-11-30 2009-12-01 Cardiac Pacemakers, Inc. Method and apparatus for cell and electrical therapy of living tissue
WO2004078065A2 (en) 2003-03-03 2004-09-16 Sinus Rhythm Technologies, Inc. Electrical conduction block implant device
US8013133B2 (en) * 2003-04-25 2011-09-06 Medtronic, Inc. Genetic modification of targeted regions of the cardiac conduction system
US20070021375A1 (en) * 2003-04-25 2007-01-25 Vinod Sharma Genetic modification of targeted regions of the cardiac conduction system
US20050021089A1 (en) * 2003-07-24 2005-01-27 Medtronic, Inc. Compositions and methods for treating cardiac dysfunction
ITRM20030376A1 (it) 2003-07-31 2005-02-01 Univ Roma Procedimento per l'isolamento e l'espansione di cellule staminali cardiache da biopsia.
EP1689284A4 (en) * 2003-11-10 2010-03-17 Symphony Medical Inc METHOD FOR REGULATING VENTRICULAR RHYTHM IN AURICULAR FIBRILLATION PATIENTS
SE526861C2 (sv) 2003-11-17 2005-11-15 Syntach Ag Vävnadslesionsskapande anordning samt en uppsättning av anordningar för behandling av störningar i hjärtrytmregleringssystemet
WO2005047500A1 (ja) * 2003-11-17 2005-05-26 Eisai Co., Ltd. hERGチャネル発現細胞
JP2007517036A (ja) * 2003-12-24 2007-06-28 ザ・トラスティーズ・オブ・コロンビア・ユニバーシティ・イン・ザ・シティ・オブ・ニューヨーク 房室ブロックを補うための生物学的房室間バイパスの作製
US20060128647A1 (en) * 2003-12-24 2006-06-15 Daniel Sigg Novel oligonucleotides and treating cardiac disorders by using the same
US8859273B2 (en) 2003-12-24 2014-10-14 Medtronic, Inc. Methods of using HCN genes to treat cardiac arrhythmias
JP2007525509A (ja) * 2004-02-26 2007-09-06 メルク　エンド　カムパニー　インコーポレーテッド 生物学的アッセイ
US7840263B2 (en) * 2004-02-27 2010-11-23 Cardiac Pacemakers, Inc. Method and apparatus for device controlled gene expression
US9398967B2 (en) 2004-03-02 2016-07-26 Syntach Ag Electrical conduction block implant device
US7764995B2 (en) 2004-06-07 2010-07-27 Cardiac Pacemakers, Inc. Method and apparatus to modulate cellular regeneration post myocardial infarct
US7729761B2 (en) * 2004-07-14 2010-06-01 Cardiac Pacemakers, Inc. Method and apparatus for controlled gene or protein delivery
US8192929B2 (en) * 2004-07-19 2012-06-05 The Trustees Of Columbia University In The City Of New York Assay system for monitoring the effects of genetically engineered cells to alter function of a synctium
WO2006049307A1 (ja) * 2004-11-02 2006-05-11 National University Corporation Tokyo Medical And Dental University リポソーム及びこれを用いた細胞に対する物質注入方法
US11660317B2 (en) 2004-11-08 2023-05-30 The Johns Hopkins University Compositions comprising cardiosphere-derived cells for use in cell therapy
US7981065B2 (en) 2004-12-20 2011-07-19 Cardiac Pacemakers, Inc. Lead electrode incorporating extracellular matrix
US8060219B2 (en) 2004-12-20 2011-11-15 Cardiac Pacemakers, Inc. Epicardial patch including isolated extracellular matrix with pacing electrodes
WO2006084322A1 (en) * 2005-02-09 2006-08-17 Craig Steven Mclachlan Treatment method for modifying tissue passive electrical conductance
US8565898B2 (en) * 2005-04-28 2013-10-22 Medtronic, Inc. Rate control during AF using cellular intervention to modulate AV node
JP2009508538A (ja) * 2005-07-29 2009-03-05 ザ・トラスティーズ・オブ・コロンビア・ユニバーシティ・イン・ザ・シティ・オブ・ニューヨーク 心臓の伝導ブロックを補償する、ナトリウムチャネル、カルシウムチャネルおよび／またはカリウムチャネルを有する生物学的バイパスブリッジ
US7774057B2 (en) * 2005-09-06 2010-08-10 Cardiac Pacemakers, Inc. Method and apparatus for device controlled gene expression for cardiac protection
JP2009511064A (ja) * 2005-10-14 2009-03-19 ザ ジョンズ ホプキンス ユニバーシティー 生物学的興奮性細胞
US20070190028A1 (en) * 2006-02-13 2007-08-16 Jihong Qu Method and apparatus for heat or electromagnetic control of gene expression
US7989207B2 (en) 2006-02-17 2011-08-02 Tyco Healthcare Group Lp Testing lumenectomy samples for markers of non-vascular diseases
KR20090035711A (ko) * 2006-07-25 2009-04-10 셀라돈 코포레이션 유전자 치료를 위한 아데노-관련 바이러스 벡터의 전방 심외막 관상에의 연장 주입
US20080082415A1 (en) * 2006-09-20 2008-04-03 Vishwanath Shastry Listing generation and advertising management utilizing catalog information
US8825677B2 (en) 2006-09-20 2014-09-02 Ebay Inc. Listing generation utilizing catalog information
WO2008079412A2 (en) * 2006-12-22 2008-07-03 The Trustees Of Columbia University In The City Of New York Methods and compositions to treat arrhythmias
US20100150887A1 (en) * 2007-01-25 2010-06-17 Duff Henry J Tissue Progenitor Cells That Overexpress ERG
US20090047703A1 (en) * 2007-08-17 2009-02-19 University Of Maryland, Baltimore ERG-1 Peptides and Polynucleotides and Their Use in the Treatment and Diagnosis of Disease
US20090054828A1 (en) * 2007-08-22 2009-02-26 Cardiac Pacemakers, Inc. Systems for transient conduction control
US8311620B2 (en) * 2007-08-22 2012-11-13 Cardiac Pacemakers, Inc. Methods and apparatus to treat and prevent atrial tachyarrhythmias
WO2009036220A2 (en) 2007-09-12 2009-03-19 The Regents Of The University Of California Compositions and methods for improving the functional efficacy of stem cell-derived cardiomyocytes
US20090233991A1 (en) * 2007-11-01 2009-09-17 Hee Cheol Cho Generation of biological pacemaker activity
KR20100129295A (ko) 2008-02-19 2010-12-08 셀라돈 코포레이션 심근 내 바이러스 벡터의 흡수를 개선시키기 위한 조성물
WO2009111755A2 (en) * 2008-03-07 2009-09-11 The Trustees Of Columbia University In The City Of New York Compensating for atrioventricular block using a nucleic acid encoding a sodium channel or gap junction protein
WO2009120082A2 (en) * 2008-03-27 2009-10-01 Academisch Medisch Centrum Bij De Universiteit Van Amsterdam Means and methods for influencing electrical activity of cells
US20100112081A1 (en) 2008-10-07 2010-05-06 Bioparadox, Llc Use of platelet rich plasma composition in the treatment of cardiac conduction abnormalities
CN102686264A (zh) * 2009-10-27 2012-09-19 雪松-西奈医疗中心 用于具有增强的细胞滞留的靶向细胞递送的外部磁力
US9393198B2 (en) * 2010-03-22 2016-07-19 Signpath Pharma Inc. Intravenous curcumin and derivatives for treatment of neurodegenerative and stress disorders
US9845457B2 (en) 2010-04-30 2017-12-19 Cedars-Sinai Medical Center Maintenance of genomic stability in cultured stem cells
US9249392B2 (en) 2010-04-30 2016-02-02 Cedars-Sinai Medical Center Methods and compositions for maintaining genomic stability in cultured stem cells
US9744132B2 (en) 2010-10-29 2017-08-29 Infirst Healthcare Limited Solid solution compositions and use in chronic inflammation
US11224659B2 (en) 2010-10-29 2022-01-18 Infirst Healthcare Limited Solid solution compositions and use in severe pain
US11730709B2 (en) 2010-10-29 2023-08-22 Infirst Healthcare Limited Compositions and methods for treating severe pain
US10695432B2 (en) * 2010-10-29 2020-06-30 Infirst Healthcare Limited Solid solution compositions and use in severe pain
US9308213B2 (en) 2010-10-29 2016-04-12 Infirst Healthcare Limited Solid solution compositions and use in chronic inflammation
US9271950B2 (en) 2010-10-29 2016-03-01 Infirst Healthcare Limited Compositions for treating chronic inflammation and inflammatory diseases
US9504664B2 (en) 2010-10-29 2016-11-29 Infirst Healthcare Limited Compositions and methods for treating severe pain
US10695431B2 (en) 2010-10-29 2020-06-30 Infirst Healthcare Limited Solid solution compositions and use in cardiovascular disease
US11202831B2 (en) 2010-10-29 2021-12-21 Infirst Healthcare Limited Solid solution compositions and use in cardiovascular disease
US8895536B2 (en) 2010-10-29 2014-11-25 Infirst Healthcare Ltd. Compositions and methods for treating chronic inflammation and inflammatory diseases
US8639323B2 (en) 2010-11-01 2014-01-28 Medtronic, Inc. System and apparatus to monitor biopacemaker maturation
US9522281B2 (en) 2010-11-18 2016-12-20 Medtronic, Inc. Varying lead configuration implantable medical device
US9592398B2 (en) 2011-05-12 2017-03-14 Medtronic, Inc. Leadless implantable medical device with osmotic pump
US10238602B2 (en) 2011-06-03 2019-03-26 Signpath Pharma, Inc. Protective effect of DMPC, DMPG, DMPC/DMPG, LysoPG and LysoPC against drugs that cause channelopathies
ES2896105T3 (es) 2011-06-03 2022-02-23 Signpath Pharma Inc Mitigación liposomal del síndrome de QT largo inducido por un fármaco y corriente rectificadora retardada de potasio
US10449193B2 (en) 2011-06-03 2019-10-22 Signpath Pharma Inc. Protective effect of DMPC, DMPG, DMPC/DMPG, lysoPG and lysoPC against drugs that cause channelopathies
WO2012167212A2 (en) 2011-06-03 2012-12-06 Signpath Pharma Inc. Liposomal mitigation of drug-induced long qt syndrome and potassium delayed-rectifier current
US10117881B2 (en) 2011-06-03 2018-11-06 Signpath Pharma, Inc. Protective effect of DMPC, DMPG, DMPC/DMPG, LYSOPG and LYSOPC against drugs that cause channelopathies
US12004868B2 (en) 2011-06-03 2024-06-11 Signpath Pharma Inc. Liposomal mitigation of drug-induced inhibition of the cardiac IKr channel
US10349884B2 (en) 2011-06-03 2019-07-16 Sighpath Pharma Inc. Liposomal mitigation of drug-induced inhibition of the cardiac ikr channel
US9681836B2 (en) 2012-04-23 2017-06-20 Cyberonics, Inc. Methods, systems and apparatuses for detecting seizure and non-seizure states
WO2013184527A1 (en) 2012-06-05 2013-12-12 Capricor, Inc. Optimized methods for generation of cardiac stem cells from cardiac tissue and their use in cardiac therapy
AU2013302799B2 (en) 2012-08-13 2018-03-01 Cedars-Sinai Medical Center Exosomes and micro-ribonucleic acids for tissue regeneration
DE112013004278T5 (de) 2012-08-31 2015-05-21 Signpath Pharma Inc. Curcumin-Er, ein liposomales PLGA-Nanocurcumin mit verlängerter oder verzögerter Freisetzung zur Minimierung der QT-Verlängerung für eine Krebstherapie
GB201309882D0 (en) * 2013-06-03 2013-07-17 Isis Innovation Prevention and treatment of atrial fibrillation
US20140356893A1 (en) 2013-06-04 2014-12-04 Allan Mishra Compositions and methods for using platelet-rich plasma for drug discovery, cell nuclear reprogramming, proliferation or differentiation
JP6895252B2 (ja) 2013-12-18 2021-06-30 サインパス ファルマ, インク.Signpath Pharma, Inc. 心筋ｉｋｒチャネルの薬剤誘発性阻害のリポソームによる軽減
US10087436B2 (en) 2014-02-06 2018-10-02 The Regents Of The University Of California Electrophysiologically mature cardiomyocytes and methods for making same
JP2017516813A (ja) 2014-06-03 2017-06-22 サインパス ファルマ, インク.Signpath Pharma, Inc. チャネル病を引き起こす薬物に対するｄｍｐｃ、ｄｍｐｇ、ｄｍｐｃ／ｄｍｐｇ、ｅｇｐｇ、ｌｙｓｏｐｇ及びｌｙｓｏｐｃの防御効果
CA2962444C (en) 2014-10-03 2023-09-05 Cedars-Sinai Medical Center Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of muscular dystrophy
WO2016059191A1 (en) * 2014-10-16 2016-04-21 Academisch Medisch Centrum Nk3 agonist for use in the treatment of a patient suffering from atrial arrhythmia or fibrillation
EP3402543B1 (en) 2016-01-11 2021-09-08 Cedars-Sinai Medical Center Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of heart failure with preserved ejection fraction
KR102638618B1 (ko) 2016-04-27 2024-02-21 사인패스 파마 인코포레이티드 약물 유발된 방실 차단의 방지
WO2017210652A1 (en) 2016-06-03 2017-12-07 Cedars-Sinai Medical Center Cdc-derived exosomes for treatment of ventricular tachyarrythmias
US11541078B2 (en) 2016-09-20 2023-01-03 Cedars-Sinai Medical Center Cardiosphere-derived cells and their extracellular vesicles to retard or reverse aging and age-related disorders
EP4699658A2 (en) 2017-04-19 2026-02-25 Cedars-Sinai Medical Center Methods and compositions for treating skeletal muscular dystrophy
US12186369B2 (en) 2017-09-20 2025-01-07 The Regents Of The University Of California Gene therapy strategy to restore electrical and cardiac function, and cardiac structure, in arrhythmogenic right ventricular cardiomyopathy
US12098385B2 (en) 2017-09-20 2024-09-24 The Regents Of The University Of California Gene therapy strategy to restore cardiac electrical and structural function in arrhythmogenic right ventricular cardiomyopathy
KR20200072479A (ko) 2017-10-19 2020-06-22 사인패스 파마 인코포레이티드 채널병증을 야기하는 약물에 대한 DMPC, DMPG, DMPC/DMPG, LysoPG 및 LysoPC의 보호 효과
US11660355B2 (en) 2017-12-20 2023-05-30 Cedars-Sinai Medical Center Engineered extracellular vesicles for enhanced tissue delivery
US12146137B2 (en) 2018-02-05 2024-11-19 Cedars-Sinai Medical Center Methods for therapeutic use of exosomes and Y-RNAS
WO2020206103A1 (en) * 2019-04-04 2020-10-08 University Of Massachusetts Ventricular arrhythmias and related methods
CN117024557B (zh) * 2023-10-10 2024-01-30 天津外泌体科技有限公司 14-3-3蛋白theta异构体作为细胞外囊泡支架蛋白的应用和细胞外囊泡

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5401629A (en) 1990-08-07 1995-03-28 The Salk Institute Biotechnology/Industrial Associates, Inc. Assay methods and compositions useful for measuring the transduction of an intracellular signal
US5163950A (en) * 1990-08-24 1992-11-17 Medical Engineering Corporation Balloon catheter and endoscope kit
WO1995022618A1 (en) 1994-02-22 1995-08-24 Dana-Farber Cancer Institute Nucleic acid delivery system, method of synthesis and uses thereof
US5662585A (en) * 1994-05-05 1997-09-02 Imagyn Medical, Inc. Endoscope with protruding member and method of utilizing the same
US5836905A (en) * 1994-06-20 1998-11-17 Lemelson; Jerome H. Apparatus and methods for gene therapy
US5824550A (en) * 1994-10-28 1998-10-20 Barnes-Jewish Hopital Voltage-gated calcium channel and antisense oligonucleotides thereto
EP0815197B1 (en) 1995-03-09 2006-01-18 University Of Utah Research Foundation Long qt genes and method for diagnosing or preventing the occurrence of long qt syndrome
US6605274B1 (en) * 1995-04-11 2003-08-12 The Regents Of The University Of California Method for in vivo regulation of cardiac muscle contractility
DK0876491T3 (da) * 1995-12-22 2009-07-06 Univ Utah Res Found Langt QT-syndrom-gen, der koder for KVLQT1 og dets association med minK
US5944710A (en) * 1996-06-24 1999-08-31 Genetronics, Inc. Electroporation-mediated intravascular delivery
DE69734885T2 (de) * 1996-08-02 2006-08-24 Elan Pharmaceuticals, Inc., South San Francisco Klasse e-spannungsabhängiger calciumkanal-antagonist und verfahren
US20020009772A1 (en) * 1997-02-28 2002-01-24 Terry P. Snutch Novel human calcium channels and related probes, cell lines and mehtods
US6086582A (en) * 1997-03-13 2000-07-11 Altman; Peter A. Cardiac drug delivery system
US6123699A (en) * 1997-09-05 2000-09-26 Cordis Webster, Inc. Omni-directional steerable catheter
US6183444B1 (en) * 1998-05-16 2001-02-06 Microheart, Inc. Drug delivery module
AU1520599A (en) 1997-11-07 1999-05-31 Johns Hopkins University, The Somatic transfer of modified genes to predict drug effects
US6703485B2 (en) * 1997-12-23 2004-03-09 The Trustees Of Columbia University In The City Of New York Brain and heart cyclic nucleotide gated ion channel compounds and uses thereof
US6776987B1 (en) * 1998-01-13 2004-08-17 Massachusetts Institute Of Technology Enhancement of cardiac chronotropy
US5965396A (en) * 1998-01-13 1999-10-12 Zeneca Limited Human lymph node derived GTPase
US6207422B1 (en) * 1998-04-17 2001-03-27 The Metrohealth System Protein that enhances expression of potassium channels on cell surfaces and nucleic acids that encode the same
US6623474B1 (en) * 1998-06-04 2003-09-23 Biosense Webster, Inc. Injection catheter with needle stop
US6365337B1 (en) * 1998-07-27 2002-04-02 University Of Iowa Research Foundation Genes encoding neuronal voltage-gated calcium channel gamma subunits
WO2000018903A2 (en) * 1998-09-29 2000-04-06 The Johns Hopkins University Inducible genetic suppression of cellular excitability
AU763049B2 (en) * 1998-12-28 2003-07-10 Arch Development Corporation Efficient and stable (in vivo) gene transfer to cardiomyocytes using recombinantadeno-associated virus vectors
US6852704B1 (en) * 1999-01-19 2005-02-08 The Children's Hospital Of Philadelphia Reverse gene therapy
US20040254134A1 (en) * 2001-04-27 2004-12-16 Eduardo Marban Biological pacemaker
EP1324780A4 (en) * 2000-09-06 2005-06-22 Univ Johns Hopkins METHODS OF TREATING CARDIAC ARRHYTHMIA
WO2002030470A1 (en) * 2000-10-13 2002-04-18 Johns Hopkins University Methods and compositions for nucleic acid delivery
US7294333B1 (en) * 2000-10-20 2007-11-13 Genegrafts Ltd. Nucleic acid constructs and cells, and methods utilizing same for modifying the electrophysiological function of excitable tissues
WO2002098287A2 (en) * 2001-06-06 2002-12-12 The Trustees Of Columbia University In The City Of New York A high throughput biological heart rate monitor that is molecularly determined
US6783979B2 (en) * 2001-06-06 2004-08-31 The Trustees Of Columbia University In The City Of New York Research Foundation Of State University Of New York Vectors encoding HCN channels and MiRP1
AU2003299204A1 (en) * 2002-10-02 2004-04-23 The Johns Hopkins University Focal calcium channel modulation
CA2526841A1 (en) * 2003-05-28 2005-04-14 Synta Pharmaceuticals Corp. Novel calcium channels and uses thereof
CA2575947A1 (en) * 2004-08-02 2006-02-16 The Johns Hopkins University Modulation of bio-electrical rhythms via a novel engineering approach
US9116846B2 (en) 2013-06-10 2015-08-25 Veeam Software Ag Virtual machine backup from storage snapshot

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US7034008B2 (en) 2006-04-25
US20040266716A1 (en) 2004-12-30
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WO2002019966A2 (en) 2002-03-14
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US20020155101A1 (en) 2002-10-24
US20150183842A1 (en) 2015-07-02
CA2421584A1 (en) 2002-03-14
US20050107323A1 (en) 2005-05-19
AU2001288807B2 (en) 2007-07-19
JP2004533405A (ja) 2004-11-04
US20070048284A1 (en) 2007-03-01
IL154769A0 (en) 2003-10-31
CA2421584C (en) 2013-12-31
US20040266717A1 (en) 2004-12-30
WO2002019966A3 (en) 2002-08-15
EP1324780A4 (en) 2005-06-22

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