IL150918A0 - Dual inhibitors of wax ester and cholesteryl ester synthesis for inhibiting sebum production - Google Patents
Dual inhibitors of wax ester and cholesteryl ester synthesis for inhibiting sebum productionInfo
- Publication number
- IL150918A0 IL150918A0 IL15091802A IL15091802A IL150918A0 IL 150918 A0 IL150918 A0 IL 150918A0 IL 15091802 A IL15091802 A IL 15091802A IL 15091802 A IL15091802 A IL 15091802A IL 150918 A0 IL150918 A0 IL 150918A0
- Authority
- IL
- Israel
- Prior art keywords
- ester
- sebum production
- dual inhibitors
- inhibiting sebum
- synthesis
- Prior art date
Links
- 239000004164 Wax ester Substances 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 title 1
- -1 cholesteryl ester Chemical class 0.000 title 1
- 230000009977 dual effect Effects 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 210000002374 sebum Anatomy 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 235000019386 wax ester Nutrition 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Toxicology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30933601P | 2001-08-01 | 2001-08-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL150918A0 true IL150918A0 (en) | 2003-02-12 |
Family
ID=23197778
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL15091802A IL150918A0 (en) | 2001-08-01 | 2002-07-25 | Dual inhibitors of wax ester and cholesteryl ester synthesis for inhibiting sebum production |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20030134898A1 (OSRAM) |
| EP (1) | EP1281399A3 (OSRAM) |
| JP (1) | JP2003104878A (OSRAM) |
| KR (1) | KR20030013289A (OSRAM) |
| CN (1) | CN1404829A (OSRAM) |
| CA (1) | CA2395006A1 (OSRAM) |
| HU (1) | HUP0202548A2 (OSRAM) |
| IL (1) | IL150918A0 (OSRAM) |
| NZ (1) | NZ520487A (OSRAM) |
| PL (1) | PL355281A1 (OSRAM) |
| ZA (1) | ZA200206032B (OSRAM) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7144911B2 (en) | 2002-12-31 | 2006-12-05 | Deciphera Pharmaceuticals Llc | Anti-inflammatory medicaments |
| US7279576B2 (en) | 2002-12-31 | 2007-10-09 | Deciphera Pharmaceuticals, Llc | Anti-cancer medicaments |
| US7202257B2 (en) | 2003-12-24 | 2007-04-10 | Deciphera Pharmaceuticals, Llc | Anti-inflammatory medicaments |
| WO2005034931A1 (en) * | 2003-10-09 | 2005-04-21 | Warner-Lambert Company Llc | Pharmaceutical compositions comprising malonamide derivatives for decreasing sebum production |
| JP5197016B2 (ja) | 2004-12-23 | 2013-05-15 | デシファラ ファーマスーティカルズ， エルエルシー | 酵素モジュレータ及び治療 |
| US8188113B2 (en) | 2006-09-14 | 2012-05-29 | Deciphera Pharmaceuticals, Inc. | Dihydropyridopyrimidinyl, dihydronaphthyidinyl and related compounds useful as kinase inhibitors for the treatment of proliferative diseases |
| US7790756B2 (en) | 2006-10-11 | 2010-09-07 | Deciphera Pharmaceuticals, Llc | Kinase inhibitors useful for the treatment of myleoproliferative diseases and other proliferative diseases |
| EP2146717A4 (en) | 2007-04-20 | 2010-08-11 | Deciphera Pharmaceuticals Llc | KINASE INHIBITORS USEFUL FOR THE TREATMENT OF MYOLEOPROLIFERATIVE DISEASES AND OTHER PROLIFERATIVE DISEASES |
| JP5444365B2 (ja) | 2008-10-29 | 2014-03-19 | デシフェラ ファーマシューティカルズ，エルエルシー | 抗癌活性および抗増殖活性を示すシクロプロパンアミドおよび類似物質 |
| US8461179B1 (en) | 2012-06-07 | 2013-06-11 | Deciphera Pharmaceuticals, Llc | Dihydronaphthyridines and related compounds useful as kinase inhibitors for the treatment of proliferative diseases |
| HK1257569A1 (zh) | 2016-02-16 | 2019-10-25 | The University Of Queensland | 磺醯脲和相关化合物及其用途 |
| GB201721185D0 (en) | 2017-12-18 | 2018-01-31 | Nodthera Ltd | Sulphonyl urea derivatives |
| CA3089630A1 (en) | 2018-01-31 | 2019-08-08 | Deciphera Pharmaceuticals, Llc | Combination therapy for the treatment of mastocytosis |
| KR20240140193A (ko) | 2018-01-31 | 2024-09-24 | 데시페라 파마슈티칼스, 엘엘씨. | 위장관 기질 종양의 치료를 위한 병용 요법 |
| EP3836917A1 (en) | 2018-08-15 | 2021-06-23 | Inflazome Limited | Novel sulfonamideurea compounds |
| ES2983661T3 (es) | 2019-06-12 | 2024-10-24 | Nodthera Ltd | Derivados de sulfonilurea y usos de los mismos |
| TWI878335B (zh) | 2019-08-12 | 2025-04-01 | 美商迪賽孚爾製藥有限公司 | 治療胃腸道基質瘤方法 |
| KR20220045189A (ko) | 2019-08-12 | 2022-04-12 | 데시페라 파마슈티칼스, 엘엘씨. | 위장관 기질 종양을 치료하는 방법 |
| EP4501931A3 (en) | 2019-12-30 | 2025-05-07 | Deciphera Pharmaceuticals, LLC | Compositions of 1-(4-bromo-5-(1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-fluoropheyl)-3-phenylurea |
| DK4084778T3 (da) | 2019-12-30 | 2023-12-11 | Deciphera Pharmaceuticals Llc | Amorfe kinaseinhibitorformuleringer og fremgangsmåder til anvendelse deraf |
| US11779572B1 (en) | 2022-09-02 | 2023-10-10 | Deciphera Pharmaceuticals, Llc | Methods of treating gastrointestinal stromal tumors |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4716175A (en) * | 1987-02-24 | 1987-12-29 | Warner-Lambert Company | Saturated fatty acid amides as inhibitors of acyl-CoA:cholesterol acyltransferase |
| US5245068A (en) * | 1990-10-30 | 1993-09-14 | Warner-Lambert Company | Oxysulfonyl carbamates |
| US5254715A (en) * | 1990-11-07 | 1993-10-19 | Warner-Lambert Company | Aminosulfonyl carbamates |
| US5214206A (en) * | 1990-11-07 | 1993-05-25 | Warner-Lambert Company | Aminosulfonyl urea acat inhibitors |
| US5198466A (en) * | 1990-11-09 | 1993-03-30 | Warner-Lambert Company | Oxysulfonyl urea acat inhibitors |
| ZA938019B (en) * | 1992-11-13 | 1995-04-28 | Upjohn Co | Pyran-2-ones and 5,6-dihydropyran-2-ones useful for treating HIV and other retroviruses |
| IL109431A (en) * | 1993-05-14 | 2001-01-11 | Warner Lambert Co | Pharmaceutical compositions containing n-acyl sulfamic acid esters (or thioesters), n-acyl sulfonamides, and n-sulfonyl carbamic acid esters (or thioesters), for regulating plasma cholesterol concentration, and certain such novel compounds |
| US5491172A (en) * | 1993-05-14 | 1996-02-13 | Warner-Lambert Company | N-acyl sulfamic acid esters (or thioesters), N-acyl sulfonamides, and N-sulfonyl carbamic acid esters (or thioesters) as hypercholesterolemic agents |
| US6133326A (en) * | 1994-08-31 | 2000-10-17 | Pfizer Inc | Compositions and methods for decreasing sebum production |
| US6730703B2 (en) * | 2000-02-02 | 2004-05-04 | Warner-Lambert Company | Dual inhibitors of cholesteryl ester and wax ester synthesis for sebaceous gland disorders |
| US6514489B1 (en) * | 2000-06-30 | 2003-02-04 | Medicis Pharmaceutical Corp. | Sulfur containing dermatological compositions and methods for reducing malodors in dermatological compositions |
| EP1357908A4 (en) * | 2001-01-30 | 2009-07-15 | Merck & Co Inc | ACYL-SULFAMIDES FOR THE TREATMENT OF OBESITY, DIABETES AND LIPID DISORDERS |
-
2002
- 2002-07-23 EP EP02255156A patent/EP1281399A3/en not_active Withdrawn
- 2002-07-25 CA CA002395006A patent/CA2395006A1/en not_active Abandoned
- 2002-07-25 IL IL15091802A patent/IL150918A0/xx unknown
- 2002-07-29 ZA ZA200206032A patent/ZA200206032B/xx unknown
- 2002-07-31 US US10/209,236 patent/US20030134898A1/en not_active Abandoned
- 2002-07-31 NZ NZ520487A patent/NZ520487A/en unknown
- 2002-07-31 PL PL02355281A patent/PL355281A1/xx not_active Application Discontinuation
- 2002-07-31 KR KR1020020045396A patent/KR20030013289A/ko not_active Ceased
- 2002-07-31 CN CN02127403A patent/CN1404829A/zh active Pending
- 2002-07-31 HU HU0202548A patent/HUP0202548A2/hu unknown
- 2002-07-31 JP JP2002222616A patent/JP2003104878A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| NZ520487A (en) | 2004-03-26 |
| HUP0202548A2 (hu) | 2003-02-28 |
| EP1281399A2 (en) | 2003-02-05 |
| CN1404829A (zh) | 2003-03-26 |
| HU0202548D0 (OSRAM) | 2002-10-28 |
| JP2003104878A (ja) | 2003-04-09 |
| PL355281A1 (en) | 2003-02-10 |
| CA2395006A1 (en) | 2003-02-01 |
| EP1281399A3 (en) | 2004-02-11 |
| US20030134898A1 (en) | 2003-07-17 |
| KR20030013289A (ko) | 2003-02-14 |
| ZA200206032B (en) | 2004-02-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL150918A0 (en) | Dual inhibitors of wax ester and cholesteryl ester synthesis for inhibiting sebum production | |
| HUP0300497A3 (en) | Inhibitors of human phosphatidyl-inositol 3-kinase delta | |
| EP1383743A4 (en) | DOUBLE INHIBITORS OF PDE 7 AND PDE 4 | |
| IL163277A (en) | Controlled synthesis of ziprasidone and compositions thereof | |
| IL154017A0 (en) | Pharmaceutical compositions of cholesteryl ester transfer protein inhibitors | |
| IL163863A0 (en) | Form of presentation for3-Ä(2-äÄ4-(hexyloxycarbonylamino-imino-methyl)-phenylaminoÜmethylü-1-methyl-1H-benzimidaz | |
| IL158765A0 (en) | Self-emulsifying formulations of cholesteryl ester transfer protein inhibitors | |
| AU2002305205A1 (en) | 9-deazaguanine derivatives as inhibitors of gsk-3 | |
| DE60127098D1 (de) | Inhibitoren der mucin-synthese | |
| AU2002346548A8 (en) | Regioisomerically pure oxochlorins and methods of synthesis | |
| HUP0105011A3 (en) | Synthesis method of nitroxymethylphenyl esters of aspirin derivatives | |
| AU2002213422A1 (en) | Synthesis of 2-hydroxymethylglutamic acid and congeners thereof | |
| GB0220861D0 (en) | Presentation of information | |
| DZ3288A1 (en) | Dual inhibitors of cholesteryl ester and wax ester synthesis for sebaceous gland disorders | |
| HUP0401641A3 (en) | Use of substituted diazonine derivatives as phosphorodiesterase iv inhibitors | |
| AU2252101A (en) | New synthesis of SPLA2 inhibitors | |
| GB2375762B (en) | Stereospecific synthesis of 2-hydroxy-4-phenyl-butyric acid esters | |
| AU2002300319A1 (en) | Dual inhibitors of wax ester and cholesteryl ester synthesis for inhibiting sebum production | |
| AU2001257253A1 (en) | Asymmetric synthesis of piperazic acid and derivatives thereof | |
| IL161608A0 (en) | Synthesis of 2-aralkoxyadenosines and 2-alkoxyadenosines | |
| PL375437A1 (en) | Synthesis of gatifloxacin | |
| PL1611083T3 (pl) | Synteza estrów kwasu 2-chlorometylo-6-metylobenzoesowego | |
| GB0225106D0 (en) | Synthesis of 3 hydroxy-5 -steroids | |
| AU2003299746A1 (en) | Total synthesis of daurichromenic acid | |
| SI1611083T1 (sl) | Sinteza estrov 2-klorometil-6-metil-benzojske kisline |