IL149890A0 - Tnt-alpha antagonist and lfa-1 antagonist for treating lfa-1 or tnf-alpha mediated - Google Patents
Tnt-alpha antagonist and lfa-1 antagonist for treating lfa-1 or tnf-alpha mediatedInfo
- Publication number
- IL149890A0 IL149890A0 IL14989000A IL14989000A IL149890A0 IL 149890 A0 IL149890 A0 IL 149890A0 IL 14989000 A IL14989000 A IL 14989000A IL 14989000 A IL14989000 A IL 14989000A IL 149890 A0 IL149890 A0 IL 149890A0
- Authority
- IL
- Israel
- Prior art keywords
- antagonist
- lfa
- alpha
- tnf
- treating
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
- C07K16/2845—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta2-subunit-containing molecules, e.g. CD11, CD18
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
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- A61P11/06—Antiasthmatics
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Neurosurgery (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- Virology (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Psychology (AREA)
- Biophysics (AREA)
- Rheumatology (AREA)
- Biochemistry (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17069699P | 1999-12-14 | 1999-12-14 | |
PCT/US2000/033875 WO2001043773A1 (en) | 1999-12-14 | 2000-12-14 | Tnf-alpha antagonist and lfa-1 antagonist for treating lfa-1 or tnf-alpha mediated disorder |
Publications (1)
Publication Number | Publication Date |
---|---|
IL149890A0 true IL149890A0 (en) | 2002-11-10 |
Family
ID=22620900
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL14989000A IL149890A0 (en) | 1999-12-14 | 2000-12-14 | Tnt-alpha antagonist and lfa-1 antagonist for treating lfa-1 or tnf-alpha mediated |
Country Status (15)
Country | Link |
---|---|
US (3) | US20010031260A1 (zh) |
EP (1) | EP1237575B1 (zh) |
JP (1) | JP2003517022A (zh) |
KR (1) | KR100567292B1 (zh) |
CN (1) | CN1409639A (zh) |
AT (1) | ATE403437T1 (zh) |
AU (1) | AU768324B2 (zh) |
CA (1) | CA2394862C (zh) |
DE (1) | DE60039783D1 (zh) |
DK (1) | DK1237575T3 (zh) |
ES (1) | ES2311483T3 (zh) |
IL (1) | IL149890A0 (zh) |
NZ (1) | NZ519222A (zh) |
PT (1) | PT1237575E (zh) |
WO (1) | WO2001043773A1 (zh) |
Families Citing this family (36)
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US7160541B2 (en) | 2000-09-01 | 2007-01-09 | The Center For Blood Research, Inc. | Modified polypeptides stabilized in a desired conformation and methods for producing same |
CN1507354A (zh) * | 2001-03-02 | 2004-06-23 | ͨ��ҽ�ƹ�˾ | 通过给予整合蛋白αvβ3拮抗剂并与其它预防或治疗药剂配合来预防或者治疗炎性疾病或自身免疫疾病的方法 |
GB0111497D0 (en) * | 2001-05-11 | 2001-07-04 | Medical Res Council | Therapeutic methods |
ES2311094T3 (es) | 2002-02-27 | 2009-02-01 | Immunex Corporation | Composicion estabilizada de tnfr-fc que comprende arginina. |
EP3210624A1 (en) * | 2002-02-27 | 2017-08-30 | Immunex Corporation | Stabilized tnfr-fc composition comprising arginine |
US20040033228A1 (en) | 2002-08-16 | 2004-02-19 | Hans-Juergen Krause | Formulation of human antibodies for treating TNF-alpha associated disorders |
EP1542768A1 (en) * | 2002-09-20 | 2005-06-22 | Alcon, Inc. | Use of cytokine synthesis inhibitors for the treatment of dry eye disorders |
CA2585024A1 (en) * | 2003-10-24 | 2005-05-06 | Azopax Therapeutics Llc | Macromer-melt formulations |
PL1682537T3 (pl) | 2003-11-05 | 2012-09-28 | Sarcode Bioscience Inc | Modulatory adhezji komórkowej |
US8697139B2 (en) | 2004-09-21 | 2014-04-15 | Frank M. Phillips | Method of intervertebral disc treatment using articular chondrocyte cells |
US7871988B1 (en) * | 2005-01-04 | 2011-01-18 | Gp Medical, Inc. | Nanoparticles for protein drug delivery |
TWI399384B (zh) | 2005-05-16 | 2013-06-21 | Abbott Biotech Ltd | TNFα抑制劑於治療侵蝕型多發性關節炎之用途 |
JP5794721B2 (ja) | 2005-05-17 | 2015-10-14 | サーコード バイオサイエンス インコーポレイテッド | 眼障害の治療のための組成物および方法 |
KR20080031684A (ko) | 2005-06-14 | 2008-04-10 | 암젠 인코포레이티드 | 자가 - 완충성 단백질 제형 |
AU2006326870A1 (en) * | 2005-12-22 | 2007-06-28 | Apollo Life Sciences | Transdermal delivery of pharmaceutical agents |
US9605064B2 (en) | 2006-04-10 | 2017-03-28 | Abbvie Biotechnology Ltd | Methods and compositions for treatment of skin disorders |
US9624295B2 (en) | 2006-04-10 | 2017-04-18 | Abbvie Biotechnology Ltd. | Uses and compositions for treatment of psoriatic arthritis |
WO2008154543A2 (en) | 2007-06-11 | 2008-12-18 | Abbott Biotechnology Ltd. | Methods for treating juvenile idiopathic arthritis |
AU2008317473B2 (en) | 2007-10-19 | 2014-07-17 | Bausch + Lomb Ireland Limited | Compositions and methods for treatment of diabetic retinopathy |
WO2009139817A2 (en) | 2008-04-15 | 2009-11-19 | Sarcode Corporation | Crystalline pharmaceutical and methods of preparation and use thereof |
CN102056485A (zh) * | 2008-04-15 | 2011-05-11 | 萨可德公司 | 用于局部治疗免疫相关疾病的局部lfa-1拮抗剂 |
WO2009128933A1 (en) * | 2008-04-15 | 2009-10-22 | Sarcode Corporation | Aerosolized lfa-1 antagonists for use in localized treatment of immune related disorders |
AU2010279511B2 (en) * | 2009-08-06 | 2014-08-14 | Anitox Corporation | Water and feed preservative |
WO2011050175A1 (en) | 2009-10-21 | 2011-04-28 | Sarcode Corporation | Crystalline pharmaceutical and methods of preparation and use thereof |
CA2818237C (en) | 2009-11-18 | 2021-05-18 | University Of Medicine And Dentistry Of New Jersey | Targeting tumor cells with chemotherapeutic agents conjugated to matriptase antibodies |
US9849192B2 (en) | 2009-11-18 | 2017-12-26 | Rutgers, The State University Of New Jersey | Targeting tumor cells with chemotherapeutic agents conjugated to matriptase antibodies |
ES2640964T3 (es) * | 2010-08-27 | 2017-11-07 | Anitox Corporation | Formulación antimicrobiana |
PL2768539T3 (pl) | 2011-10-20 | 2017-07-31 | Anitox Corporation | Formulacje przeciwdrobnoustrojowe z kwasem pelargonowym |
HUE053434T2 (hu) | 2011-11-30 | 2021-06-28 | Anitox Corp | Aldehidek, szerves savak és szerves savak észtereinek antimikrobiális keveréke |
AU2013295706A1 (en) | 2012-07-25 | 2015-02-19 | Sarcode Bioscience Inc. | LFA-1 inhibitor and polymorph thereof |
WO2014046631A1 (en) | 2012-09-19 | 2014-03-27 | Tezcaner Aysen | CONTROLED DRUG DELIVERY SYSTEMS FOR ANTI-TNF-α |
WO2014055663A1 (en) * | 2012-10-02 | 2014-04-10 | Rutgers, The State University Of New Jersey | Specific delivery of toxins conjugated wtih antibodies to activated matriptase |
EP3268042A4 (en) * | 2015-03-13 | 2018-08-01 | Samsung Bioepis Co., Ltd. | Anti-tnf-alpha polypeptide composition and use thereof |
RU2613056C1 (ru) * | 2016-03-14 | 2017-03-15 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Южно-Уральский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ГБОУ ВПО ЮУГМУ Минздрава России) | Способ прогнозирования развития увеита у детей с ювенильным идиопатическим артритом |
JP7145374B2 (ja) | 2016-03-18 | 2022-10-03 | ラトガース ザ ステイト ユニバーシティー オブ ニュージャージー | インビボでの切断可能連結部分によって抗マトリプターゼ抗体にコンジュゲートされた化学療法剤を用いる腫瘍細胞の標的化 |
BR112019007858A2 (pt) | 2016-10-21 | 2019-07-02 | Amgen Inc | formulações farmacêuticas e métodos para produzir as mesmas |
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US5225538A (en) * | 1989-02-23 | 1993-07-06 | Genentech, Inc. | Lymphocyte homing receptor/immunoglobulin fusion proteins |
US5690933A (en) * | 1989-05-31 | 1997-11-25 | Glaxo Wellcome Inc. | Monoclonal antibodies for inducing tolerance |
NZ235148A (en) * | 1989-09-05 | 1991-12-23 | Immunex Corp | Tumour necrosis factor receptor protein and dna sequences |
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-
2000
- 2000-12-14 AT AT00986377T patent/ATE403437T1/de not_active IP Right Cessation
- 2000-12-14 WO PCT/US2000/033875 patent/WO2001043773A1/en active IP Right Grant
- 2000-12-14 US US09/738,540 patent/US20010031260A1/en not_active Abandoned
- 2000-12-14 AU AU54397/01A patent/AU768324B2/en not_active Ceased
- 2000-12-14 KR KR1020027007537A patent/KR100567292B1/ko not_active IP Right Cessation
- 2000-12-14 IL IL14989000A patent/IL149890A0/xx unknown
- 2000-12-14 NZ NZ519222A patent/NZ519222A/en not_active IP Right Cessation
- 2000-12-14 CN CN00817171A patent/CN1409639A/zh active Pending
- 2000-12-14 EP EP00986377A patent/EP1237575B1/en not_active Expired - Lifetime
- 2000-12-14 JP JP2001544909A patent/JP2003517022A/ja active Pending
- 2000-12-14 CA CA2394862A patent/CA2394862C/en not_active Expired - Fee Related
- 2000-12-14 DE DE60039783T patent/DE60039783D1/de not_active Expired - Lifetime
- 2000-12-14 ES ES00986377T patent/ES2311483T3/es not_active Expired - Lifetime
- 2000-12-14 PT PT00986377T patent/PT1237575E/pt unknown
- 2000-12-14 DK DK00986377T patent/DK1237575T3/da active
-
2005
- 2005-05-12 US US11/128,912 patent/US20050214291A1/en not_active Abandoned
-
2007
- 2007-07-26 US US11/828,977 patent/US20080031875A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2001043773A1 (en) | 2001-06-21 |
CA2394862C (en) | 2011-10-11 |
CN1409639A (zh) | 2003-04-09 |
US20010031260A1 (en) | 2001-10-18 |
KR100567292B1 (ko) | 2006-04-04 |
US20080031875A1 (en) | 2008-02-07 |
US20050214291A1 (en) | 2005-09-29 |
EP1237575A1 (en) | 2002-09-11 |
AU768324B2 (en) | 2003-12-11 |
ES2311483T3 (es) | 2009-02-16 |
KR20020068372A (ko) | 2002-08-27 |
JP2003517022A (ja) | 2003-05-20 |
PT1237575E (pt) | 2008-11-17 |
ATE403437T1 (de) | 2008-08-15 |
DK1237575T3 (da) | 2008-12-08 |
NZ519222A (en) | 2004-04-30 |
AU5439701A (en) | 2001-06-25 |
EP1237575B1 (en) | 2008-08-06 |
DE60039783D1 (de) | 2008-09-18 |
CA2394862A1 (en) | 2001-06-21 |
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