IL149402A0 - Arylamine derivatives and their use as anti-telomerase agent - Google Patents
Arylamine derivatives and their use as anti-telomerase agentInfo
- Publication number
- IL149402A0 IL149402A0 IL14940200A IL14940200A IL149402A0 IL 149402 A0 IL149402 A0 IL 149402A0 IL 14940200 A IL14940200 A IL 14940200A IL 14940200 A IL14940200 A IL 14940200A IL 149402 A0 IL149402 A0 IL 149402A0
- Authority
- IL
- Israel
- Prior art keywords
- arylamine derivatives
- telomerase agent
- telomerase
- agent
- concerns
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
- C07D215/46—Nitrogen atoms attached in position 4 with hydrocarbon radicals, substituted by nitrogen atoms, attached to said nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
- C07D251/40—Nitrogen atoms
- C07D251/54—Three nitrogen atoms
- C07D251/70—Other substituted melamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Quinoline Compounds (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9915031A FR2801588B1 (fr) | 1999-11-29 | 1999-11-29 | Derives chimiques et leur application comme agent antitelomerase |
FR0010561 | 2000-08-11 | ||
PCT/FR2000/003310 WO2001040218A1 (fr) | 1999-11-29 | 2000-11-27 | Derives arylamines et leur application comme agent antitelomerase |
Publications (1)
Publication Number | Publication Date |
---|---|
IL149402A0 true IL149402A0 (en) | 2002-11-10 |
Family
ID=26212577
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL14940200A IL149402A0 (en) | 1999-11-29 | 2000-11-27 | Arylamine derivatives and their use as anti-telomerase agent |
Country Status (27)
Country | Link |
---|---|
EP (1) | EP1244650B1 (et) |
JP (1) | JP2003515604A (et) |
KR (1) | KR20020058043A (et) |
CN (1) | CN1402722A (et) |
AT (1) | ATE243692T1 (et) |
AU (1) | AU2179001A (et) |
BG (1) | BG106753A (et) |
BR (1) | BR0015992A (et) |
CA (1) | CA2392507A1 (et) |
CO (1) | CO5251431A1 (et) |
CZ (1) | CZ20021849A3 (et) |
DE (1) | DE60003583T2 (et) |
DK (1) | DK1244650T3 (et) |
EA (1) | EA200200616A1 (et) |
EE (1) | EE200200263A (et) |
ES (1) | ES2202206T3 (et) |
HU (1) | HUP0204429A2 (et) |
IL (1) | IL149402A0 (et) |
MX (1) | MXPA02005276A (et) |
NO (1) | NO20022528D0 (et) |
PE (1) | PE20010912A1 (et) |
PL (1) | PL355667A1 (et) |
PT (1) | PT1244650E (et) |
SK (1) | SK7402002A3 (et) |
UY (1) | UY26456A1 (et) |
WO (1) | WO2001040218A1 (et) |
YU (1) | YU38102A (et) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001025220A1 (en) | 1999-10-07 | 2001-04-12 | Amgen Inc. | Triazine kinase inhibitors |
AU2001228638A1 (en) | 2000-01-28 | 2001-08-07 | Astrazeneca Ab | Chemical compounds |
HUP0301117A3 (en) | 2000-02-17 | 2004-01-28 | Amgen Inc Thousand Oaks | Imidazole derivatives kinase inhibitors, their use, process for their preparation and pharmaceutical compositions containing them |
AU2001282268A1 (en) * | 2000-08-08 | 2002-02-18 | Aventis Pharma S.A. | Phenantridine derivatives and their use as anti-telomerase agent |
NZ526542A (en) | 2000-12-21 | 2005-01-28 | Glaxo Group Ltd | Pyrimidineamines as angiogenesis modulators |
FR2821355A1 (fr) * | 2001-02-23 | 2002-08-30 | Aventis Pharma Sa | Derives chimiques et leur application comme agent antitelomerase |
US6887873B2 (en) | 2001-03-23 | 2005-05-03 | Aventis Pharma S.A. | Triazine derivatives and their application as antitelomerase agents |
CO5380035A1 (es) * | 2001-03-23 | 2004-03-31 | Aventis Pharma Sa | Derivados quimicos y su aplicacion como agente antitelomerasa |
FR2822468B1 (fr) * | 2001-03-23 | 2008-06-20 | Aventis Pharma Sa | Derives chimiques et leur application comme agent anti-telomerase |
JP2004534046A (ja) * | 2001-05-28 | 2004-11-11 | アベンティス・ファーマ・ソシエテ・アノニム | 化学誘導体および抗テロメラーゼ剤としてのその使用 |
US6939874B2 (en) * | 2001-08-22 | 2005-09-06 | Amgen Inc. | Substituted pyrimidinyl derivatives and methods of use |
US7115617B2 (en) | 2001-08-22 | 2006-10-03 | Amgen Inc. | Amino-substituted pyrimidinyl derivatives and methods of use |
US7112587B2 (en) | 2001-09-21 | 2006-09-26 | Reddy Us Therapeutics, Inc. | Methods and compositions of novel triazine compounds |
US7132423B2 (en) | 2001-09-21 | 2006-11-07 | Reddy Us Therapeutics, Inc. | Methods and compositions of novel triazine compounds |
US7169785B2 (en) | 2001-09-21 | 2007-01-30 | Reddy Us Therapeutics, Inc. | Methods and compositions of novel triazine compounds |
US7163943B2 (en) | 2001-09-21 | 2007-01-16 | Reddy Us Therapeutics, Inc. | Methods and compositions of novel triazine compounds |
US7173032B2 (en) | 2001-09-21 | 2007-02-06 | Reddy Us Therapeutics, Inc. | Methods and compositions of novel triazine compounds |
US7084156B2 (en) | 2001-11-27 | 2006-08-01 | Merck & Co., Inc. | 2-Aminoquinoline compounds |
CA2498281A1 (en) * | 2002-09-10 | 2004-03-25 | Pharmacia Italia S.P.A. | Substituted pyridine derivatives as antitumor agent |
AU2003275726A1 (en) * | 2002-10-24 | 2004-05-13 | Chong Kun Dang Pharmaceutical Corp. | 2 - substituted heterocyclic compounds and antitumor composition comprising the same |
FR2850970B1 (fr) * | 2003-02-07 | 2006-07-07 | Aventis Pharma Sa | Derives chimiques se liant de maniere tres specifique aux structures d'adn en g-quadruplexe et leur application comme agent anticancereux specifique |
JP4691041B2 (ja) * | 2003-11-20 | 2011-06-01 | チルドレンズ ホスピタル メディカル センター | Gtpアーゼ阻害剤および使用方法 |
US7335770B2 (en) | 2004-03-24 | 2008-02-26 | Reddy U5 Therapeutics, Inc. | Triazine compounds and their analogs, compositions, and methods |
JP5548363B2 (ja) | 2005-10-28 | 2014-07-16 | アルマック サイエンシーズ (スコットランド) リミテッド | 新規な蛍光染料およびその使用 |
US7713987B2 (en) | 2005-12-06 | 2010-05-11 | Rigel Pharmaceuticals, Inc. | Pyrimidine-2,4-diamines and their uses |
KR100761869B1 (ko) * | 2006-07-07 | 2007-10-04 | 김현기 | 트리아진 유도체 화합물 및 이를 포함하는 암 치료용조성물 |
EP2441757A1 (en) * | 2006-07-31 | 2012-04-18 | Praecis Pharmaceuticals Incorporated | Aurora kinase inhibitors from an encoded small molecule library |
JP5325517B2 (ja) * | 2007-10-12 | 2013-10-23 | 住友化学株式会社 | ジベンゾオキセピン化合物の精製方法 |
JP2009102249A (ja) * | 2007-10-22 | 2009-05-14 | Sumitomo Chemical Co Ltd | ジベンゾオキセピン化合物の結晶の製造方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9206768D0 (en) * | 1992-03-27 | 1992-05-13 | Jarman Michael | New compounds for use in the treatment of cancer |
US5770613A (en) * | 1995-09-29 | 1998-06-23 | Geron Corporation | Telomerase inhibitors |
JPH1160573A (ja) * | 1997-08-22 | 1999-03-02 | Nippon Kayaku Co Ltd | トリアジン誘導体及びテロメラーゼ阻害剤 |
DE69909246D1 (de) * | 1998-02-04 | 2003-08-07 | Univ Texas | Hemmung der menschlichen telomerase durch g-quadruplex interaktionverbindung |
DE19812879A1 (de) * | 1998-03-24 | 1999-09-30 | Bayer Ag | Substituierte 2,4-Diamino-1,3,5-triazine |
-
2000
- 2000-11-27 EP EP00985339A patent/EP1244650B1/fr not_active Expired - Lifetime
- 2000-11-27 JP JP2001541902A patent/JP2003515604A/ja not_active Withdrawn
- 2000-11-27 YU YU38102A patent/YU38102A/sh unknown
- 2000-11-27 DK DK00985339T patent/DK1244650T3/da active
- 2000-11-27 AT AT00985339T patent/ATE243692T1/de not_active IP Right Cessation
- 2000-11-27 PL PL00355667A patent/PL355667A1/xx not_active Application Discontinuation
- 2000-11-27 HU HU0204429A patent/HUP0204429A2/hu unknown
- 2000-11-27 MX MXPA02005276A patent/MXPA02005276A/es unknown
- 2000-11-27 PT PT00985339T patent/PT1244650E/pt unknown
- 2000-11-27 EE EEP200200263A patent/EE200200263A/et unknown
- 2000-11-27 CN CN00816440A patent/CN1402722A/zh active Pending
- 2000-11-27 AU AU21790/01A patent/AU2179001A/en not_active Abandoned
- 2000-11-27 EA EA200200616A patent/EA200200616A1/ru unknown
- 2000-11-27 CA CA002392507A patent/CA2392507A1/fr not_active Abandoned
- 2000-11-27 ES ES00985339T patent/ES2202206T3/es not_active Expired - Lifetime
- 2000-11-27 BR BR0015992-1A patent/BR0015992A/pt not_active IP Right Cessation
- 2000-11-27 DE DE60003583T patent/DE60003583T2/de not_active Expired - Fee Related
- 2000-11-27 CZ CZ20021849A patent/CZ20021849A3/cs unknown
- 2000-11-27 SK SK740-2002A patent/SK7402002A3/sk unknown
- 2000-11-27 IL IL14940200A patent/IL149402A0/xx unknown
- 2000-11-27 WO PCT/FR2000/003310 patent/WO2001040218A1/fr not_active Application Discontinuation
- 2000-11-27 KR KR1020027006786A patent/KR20020058043A/ko not_active Application Discontinuation
- 2000-11-28 PE PE2000001265A patent/PE20010912A1/es not_active Application Discontinuation
- 2000-11-28 UY UY26456A patent/UY26456A1/es not_active Application Discontinuation
- 2000-11-28 CO CO00090981A patent/CO5251431A1/es not_active Application Discontinuation
-
2002
- 2002-05-28 NO NO20022528A patent/NO20022528D0/no not_active Application Discontinuation
- 2002-05-29 BG BG106753A patent/BG106753A/bg unknown
Also Published As
Publication number | Publication date |
---|---|
JP2003515604A (ja) | 2003-05-07 |
MXPA02005276A (es) | 2002-11-07 |
BR0015992A (pt) | 2002-08-06 |
EP1244650B1 (fr) | 2003-06-25 |
EP1244650A1 (fr) | 2002-10-02 |
EE200200263A (et) | 2003-06-16 |
YU38102A (sh) | 2004-12-31 |
DE60003583T2 (de) | 2004-05-13 |
DE60003583D1 (de) | 2003-07-31 |
AU2179001A (en) | 2001-06-12 |
CA2392507A1 (fr) | 2001-06-07 |
UY26456A1 (es) | 2001-06-29 |
PE20010912A1 (es) | 2001-09-01 |
PL355667A1 (en) | 2004-05-04 |
ATE243692T1 (de) | 2003-07-15 |
PT1244650E (pt) | 2003-11-28 |
BG106753A (bg) | 2003-02-28 |
DK1244650T3 (da) | 2003-10-20 |
SK7402002A3 (en) | 2002-11-06 |
CZ20021849A3 (cs) | 2002-08-14 |
CO5251431A1 (es) | 2003-02-28 |
KR20020058043A (ko) | 2002-07-12 |
EA200200616A1 (ru) | 2002-10-31 |
NO20022528L (no) | 2002-05-28 |
CN1402722A (zh) | 2003-03-12 |
WO2001040218A1 (fr) | 2001-06-07 |
HUP0204429A2 (hu) | 2003-04-28 |
NO20022528D0 (no) | 2002-05-28 |
ES2202206T3 (es) | 2004-04-01 |
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