IL148088A0 - Methods and apparatuses for stretching polymers - Google Patents
Methods and apparatuses for stretching polymersInfo
- Publication number
- IL148088A0 IL148088A0 IL14808800A IL14808800A IL148088A0 IL 148088 A0 IL148088 A0 IL 148088A0 IL 14808800 A IL14808800 A IL 14808800A IL 14808800 A IL14808800 A IL 14808800A IL 148088 A0 IL148088 A0 IL 148088A0
- Authority
- IL
- Israel
- Prior art keywords
- apparatuses
- methods
- stretching polymers
- stretching
- polymers
- Prior art date
Links
- 229920000642 polymer Polymers 0.000 title 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/40—Static mixers
- B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
- B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
- B01F25/431—Straight mixing tubes with baffles or obstructions that do not cause substantial pressure drop; Baffles therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/40—Static mixers
- B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
- B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
- B01F25/432—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction with means for dividing the material flow into separate sub-flows and for repositioning and recombining these sub-flows; Cross-mixing, e.g. conducting the outer layer of the material nearer to the axis of the tube or vice-versa
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/40—Static mixers
- B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
- B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
- B01F25/433—Mixing tubes wherein the shape of the tube influences the mixing, e.g. mixing tubes with varying cross-section or provided with inwardly extending profiles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
- B01L2200/0663—Stretching or orienting elongated molecules or particles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0694—Creating chemical gradients in a fluid
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0681—Filter
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0883—Serpentine channels
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/08—Regulating or influencing the flow resistance
- B01L2400/084—Passive control of flow resistance
- B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
- B01L3/502776—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for focusing or laminating flows
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/44—Resins; Plastics; Rubber; Leather
- G01N33/442—Resins; Plastics
Landscapes
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Physics & Mathematics (AREA)
- Fluid Mechanics (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14902099P | 1999-08-13 | 1999-08-13 | |
PCT/US2000/022253 WO2001013088A1 (en) | 1999-08-13 | 2000-08-11 | Methods and apparatuses for stretching polymers |
Publications (1)
Publication Number | Publication Date |
---|---|
IL148088A0 true IL148088A0 (en) | 2002-09-12 |
Family
ID=22528446
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL14808800A IL148088A0 (en) | 1999-08-13 | 2000-08-11 | Methods and apparatuses for stretching polymers |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP1210578A4 (xx) |
JP (1) | JP2003507026A (xx) |
CN (1) | CN1379857A (xx) |
AU (1) | AU6771100A (xx) |
CA (1) | CA2381361A1 (xx) |
IL (1) | IL148088A0 (xx) |
WO (1) | WO2001013088A1 (xx) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7056661B2 (en) | 1999-05-19 | 2006-06-06 | Cornell Research Foundation, Inc. | Method for sequencing nucleic acid molecules |
US6927065B2 (en) | 1999-08-13 | 2005-08-09 | U.S. Genomics, Inc. | Methods and apparatus for characterization of single polymers |
US7211414B2 (en) | 2000-12-01 | 2007-05-01 | Visigen Biotechnologies, Inc. | Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity |
EP1370690B1 (en) | 2001-03-16 | 2012-03-14 | Kalim Mir | Arrays and methods of use |
US8423294B2 (en) | 2001-09-18 | 2013-04-16 | Pathogenetix, Inc. | High resolution linear analysis of polymers |
GB0125436D0 (en) * | 2001-10-23 | 2001-12-12 | Deltadot Ltd | Analysis of temperature-dependent molecular configurations |
EP2484751B1 (en) * | 2002-04-16 | 2018-11-28 | Princeton University | Method of analysing polynucleotides |
US7282330B2 (en) | 2002-05-28 | 2007-10-16 | U.S. Genomics, Inc. | Methods and apparati using single polymer analysis |
US7371520B2 (en) | 2002-05-28 | 2008-05-13 | U.S. Genomics, Inc. | Methods and apparati using single polymer analysis |
JP2005533256A (ja) * | 2002-07-17 | 2005-11-04 | ユー.エス. ジェノミクス, インコーポレイテッド | キメラタグを用いるポリマーを分析するための方法と組成物 |
WO2004091795A2 (en) * | 2003-04-10 | 2004-10-28 | U.S. Genomics, Inc. | Manipulation of polymers in a microchannel |
US20070026456A1 (en) * | 2003-09-02 | 2007-02-01 | Nec Corporation | Method of biomolecule analysis and method of identifying biomolecule therewith |
US7595160B2 (en) | 2004-01-13 | 2009-09-29 | U.S. Genomics, Inc. | Analyte detection using barcoded polymers |
US7977048B2 (en) | 2004-01-13 | 2011-07-12 | Pathogenetix, Inc. | Detection and quantification of analytes in solution using polymers |
AP2773A (en) * | 2004-05-13 | 2013-09-30 | Nanobiosym Inc | NANO-PCR: Methods and devices for nucleic acid amplification and detection |
ZA200609413B (en) * | 2004-05-13 | 2008-09-25 | Goel Anita | Nano-PCR: Methods and devices for nucleic acid amplification and detection |
US7170050B2 (en) | 2004-09-17 | 2007-01-30 | Pacific Biosciences Of California, Inc. | Apparatus and methods for optical analysis of molecules |
EP1963500B1 (en) * | 2005-12-23 | 2013-02-13 | Nanostring Technologies, Inc. | Compositions comprising oriented, immobilized macromolecules and methods for their preparation |
WO2007124105A2 (en) | 2006-04-21 | 2007-11-01 | Nanobiosym, Inc. | Single-molecule platform for drug discovery: methods and apparatuses for drug discovery, including discovery of anticancer and antiviral agents |
US7595150B2 (en) * | 2006-06-30 | 2009-09-29 | Searete Llc | Method of applying an elongated molecule to a surface |
CN103203256B (zh) * | 2006-07-19 | 2015-09-23 | 博纳基因技术有限公司 | 纳米口装置阵列:它们的制备以及在大分子分析中的应用 |
WO2008108237A1 (ja) * | 2007-03-02 | 2008-09-12 | Seishin Enterprise Co., Ltd. | フローセル及びそれを備えた粒子形状分析装置 |
CN101765462B (zh) | 2007-03-28 | 2013-06-05 | 博纳基因技术有限公司 | 使用纳米通道阵列的大分子分析方法 |
CN101772697B (zh) * | 2007-06-07 | 2013-08-21 | 技术研究及发展基金有限公司 | 用于聚集颗粒的系统和方法 |
US8367424B2 (en) | 2007-10-15 | 2013-02-05 | Rohm Co., Ltd. | Microchip and method of using the same |
JP2011515102A (ja) | 2008-03-28 | 2011-05-19 | パシフィック バイオサイエンシーズ オブ カリフォルニア, インコーポレイテッド | 核酸シーケンシング用組成物及び方法 |
CN102369059B (zh) * | 2008-06-06 | 2014-09-24 | 博纳基因技术有限公司 | 集成分析装置及相关制造方法和分析技术 |
CA2729159C (en) | 2008-06-30 | 2020-01-14 | Bionanomatrix, Inc. | Methods and devices for single-molecule whole genome analysis |
CN104372080B (zh) | 2008-11-18 | 2018-03-30 | 博纳基因技术有限公司 | 多核苷酸作图和测序 |
US9194838B2 (en) | 2010-03-03 | 2015-11-24 | Osaka University | Method and device for identifying nucleotide, and method and device for determining nucleotide sequence of polynucleotide |
GB201111237D0 (en) * | 2011-06-30 | 2011-08-17 | Isis Innovation | Nanochip |
US11053535B2 (en) | 2011-09-12 | 2021-07-06 | The University Of North Carolina At Chapel Hill | Devices with a fluid transport nanochannel intersected by a fluid sensing nanochannel and related methods |
EP2570488A1 (en) * | 2011-09-16 | 2013-03-20 | Centre National de la Recherche Scientifique (C.N.R.S) | Method for longitudinal macromolecule spreading and method for analyzing macromolecules |
US9989515B2 (en) | 2012-02-10 | 2018-06-05 | The University Of North Carolina At Chapel Hill | Devices with fluidic nanofunnels, associated methods, fabrication and analysis systems |
CN104272089B (zh) * | 2012-03-05 | 2017-05-10 | 松下知识产权经营株式会社 | 传感器设备 |
WO2013158860A1 (en) * | 2012-04-18 | 2013-10-24 | Pathogenetix, Inc. | Devices and methods for nucleic acid preparation and analysis |
WO2014027580A1 (ja) | 2012-08-17 | 2014-02-20 | 国立大学法人大阪大学 | 試料の分析方法 |
EP2962117B1 (en) | 2013-02-28 | 2019-10-09 | The University of North Carolina At Chapel Hill | Nanofluidic devices with integrated components for the controlled capture, trapping, and transport of macromolecules and related methods of analysis |
JP2014173934A (ja) * | 2013-03-07 | 2014-09-22 | Toshiba Corp | 半導体マイクロ分析チップ及びその製造方法 |
EP2971181B1 (en) | 2013-03-13 | 2019-02-20 | The University of North Carolina At Chapel Hill | Nanofluidic devices for the rapid mapping of whole genomes and related systems and methods of analysis |
US10933417B2 (en) | 2013-03-15 | 2021-03-02 | Nanobiosym, Inc. | Systems and methods for mobile device analysis of nucleic acids and proteins |
CN104368250B (zh) * | 2013-08-13 | 2017-12-22 | 北京慧荣和科技有限公司 | 气体或气溶胶混合或稀释装置 |
EP3047282B1 (en) | 2013-09-18 | 2019-05-15 | Quantum Biosystems Inc. | Biomolecule sequencing devices, systems and methods |
JP2015077652A (ja) | 2013-10-16 | 2015-04-23 | クオンタムバイオシステムズ株式会社 | ナノギャップ電極およびその製造方法 |
CN106414767A (zh) * | 2014-01-24 | 2017-02-15 | 量子生物有限公司 | 生物分子的测序装置、系统及方法 |
US10438811B1 (en) | 2014-04-15 | 2019-10-08 | Quantum Biosystems Inc. | Methods for forming nano-gap electrodes for use in nanosensors |
WO2015170782A1 (en) * | 2014-05-08 | 2015-11-12 | Osaka University | Devices, systems and methods for linearization of polymers |
US10471428B2 (en) | 2015-05-11 | 2019-11-12 | The University Of North Carolina At Chapel Hill | Fluidic devices with nanoscale manifolds for molecular transport, related systems and methods of analysis |
GB2608517B (en) | 2017-11-30 | 2023-03-29 | Axalta Coating Systems Gmbh | Coating compositions for application utilizing a high transfer efficiency applicator and methods and systems thereof |
WO2020124263A1 (en) * | 2018-12-21 | 2020-06-25 | Nanorial Technologies Ltd. | Apparatus, methods, and systems for mixing, dispersing substances |
CN112473418B (zh) * | 2020-11-06 | 2021-07-02 | 中国石油大学(北京) | 一种连续油管用超干二氧化碳泡沫发生装置及其应用 |
CN113617402A (zh) * | 2021-07-07 | 2021-11-09 | 福建农林大学 | 产生剪切和拉伸组合流场的微流芯片、装置及其应用方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3123249B2 (ja) * | 1991-09-10 | 2001-01-09 | 株式会社日立製作所 | Dna分子の長さ計測方法および計測装置 |
US5538898A (en) * | 1995-03-16 | 1996-07-23 | International Business Machines Corporation | Method suitable for identifying a code sequence of a biomolecule |
US5846832A (en) * | 1995-09-20 | 1998-12-08 | The Board Of Trustees Of The Leland Stanford Junior University | Apparatus and method for shear breakage of polynucleotides |
WO1999009042A2 (en) * | 1997-08-13 | 1999-02-25 | Cepheid | Microstructures for the manipulation of fluid samples |
JP2002522780A (ja) * | 1998-08-13 | 2002-07-23 | ユー.エス.ゲノミクス | ポリマーの光学的な特性決定 |
-
2000
- 2000-08-11 CA CA002381361A patent/CA2381361A1/en not_active Abandoned
- 2000-08-11 IL IL14808800A patent/IL148088A0/xx unknown
- 2000-08-11 WO PCT/US2000/022253 patent/WO2001013088A1/en active Application Filing
- 2000-08-11 JP JP2001517140A patent/JP2003507026A/ja active Pending
- 2000-08-11 AU AU67711/00A patent/AU6771100A/en not_active Abandoned
- 2000-08-11 CN CN00814266A patent/CN1379857A/zh active Pending
- 2000-08-11 EP EP00955515A patent/EP1210578A4/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
AU6771100A (en) | 2001-03-13 |
WO2001013088A1 (en) | 2001-02-22 |
EP1210578A4 (en) | 2007-02-21 |
CN1379857A (zh) | 2002-11-13 |
CA2381361A1 (en) | 2001-02-22 |
JP2003507026A (ja) | 2003-02-25 |
EP1210578A1 (en) | 2002-06-05 |
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