IL147477A - Preparation of medication comprising citicoline together with a second pharmaceutical agent for protecting brain tissue from infraction following ischemia - Google Patents

Preparation of medication comprising citicoline together with a second pharmaceutical agent for protecting brain tissue from infraction following ischemia

Info

Publication number
IL147477A
IL147477A IL147477A IL14747796A IL147477A IL 147477 A IL147477 A IL 147477A IL 147477 A IL147477 A IL 147477A IL 14747796 A IL14747796 A IL 14747796A IL 147477 A IL147477 A IL 147477A
Authority
IL
Israel
Prior art keywords
citicoline
agents
ischemia
therapeutic agent
salt
Prior art date
Application number
IL147477A
Other languages
English (en)
Inventor
Bobby W Sandage Jr
Marc Fisher
Kenneth W Locke
Original Assignee
Bobby W Sandage Jr
Marc Fisher
Kenneth W Locke
Ferrer Int
Indevus Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23578854&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL147477(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bobby W Sandage Jr, Marc Fisher, Kenneth W Locke, Ferrer Int, Indevus Pharmaceuticals Inc filed Critical Bobby W Sandage Jr
Publication of IL147477A publication Critical patent/IL147477A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL147477A 1995-03-06 1996-03-05 Preparation of medication comprising citicoline together with a second pharmaceutical agent for protecting brain tissue from infraction following ischemia IL147477A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39926295A 1995-03-06 1995-03-06
US08/603,102 US5872108A (en) 1995-03-06 1996-02-20 Reduction of infarct volume using citicoline

Publications (1)

Publication Number Publication Date
IL147477A true IL147477A (en) 2010-02-17

Family

ID=23578854

Family Applications (1)

Application Number Title Priority Date Filing Date
IL147477A IL147477A (en) 1995-03-06 1996-03-05 Preparation of medication comprising citicoline together with a second pharmaceutical agent for protecting brain tissue from infraction following ischemia

Country Status (5)

Country Link
US (2) US5872108A (fr)
KR (1) KR19980702724A (fr)
IL (1) IL147477A (fr)
IN (1) IN182555B (fr)
ZA (1) ZA961791B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6732369B1 (en) * 1995-10-02 2004-05-04 Starsight Telecast, Inc. Systems and methods for contextually linking television program information
JP4530534B2 (ja) * 1997-12-24 2010-08-25 フエルレル インターナショナル、ソシエダッド アノニマ 超水和シチコリン、プロセスおよび使用
US6379882B1 (en) * 1998-09-14 2002-04-30 Elan Pharmaceuticals, Inc. Method for selecting compounds for treating ischemia-related cellular damage
ES2169986B1 (es) 2000-03-14 2003-06-16 Ferrer Int Uso de cdp-colina para el tratamiento profilactico de la isquemia cerebral.
CA2429196A1 (fr) * 2000-03-24 2001-10-04 Duke University Caracterisation d'interactions ligands-grp94 et methodes de purification, de criblage et de traitement associees
US7235649B2 (en) * 2000-03-24 2007-06-26 Duke University Isolated GRP94 ligand binding domain polypeptide and nucleic acid encoding same, and screening methods employing same
US7034054B2 (en) * 2000-12-15 2006-04-25 Galileo Pharmaceuticals, Inc. Methods for the prevention and treatment of cerebral ischemia using non-alpha tocopherols
WO2003100570A2 (fr) * 2002-05-23 2003-12-04 New England Medical Center Hospitals, Inc. Selection de patient multidimensionnelle assistee par ordinateur
WO2005112635A2 (fr) * 2004-05-13 2005-12-01 Massachusetts Institute Of Technology Effets de l'uridine sur la liberation de la dopamine
EP2471530B1 (fr) 2005-06-01 2017-01-11 Edison Pharmaceuticals, Inc. Produits therapeutiques actifs en reduction-oxydation destines au traitement de maladies mitochondriales et d'autres etats ainsi que la modulation de bio-marqueurs d'energie
CA2635280C (fr) 2006-02-22 2017-12-12 Edison Pharmaceuticals, Inc. Variants a chaines laterales d'agents therapeutiques ayant une activite oxydoreductrice pour le traitement de maladies mitochondriales et d'autres conditions et pour la modulationde biomarqueurs energetiques
CN102647981B (zh) 2009-08-26 2016-09-28 爱迪生制药有限公司 预防和治疗脑缺血的方法
JP2011178687A (ja) * 2010-02-26 2011-09-15 Kochi Univ 造血細胞移植に伴う疼痛の予防および／または治療剤
US20140099262A1 (en) 2011-06-01 2014-04-10 Brain Watch Ltd. Isotopically labeled cdp-choline and uses thereof
JP6124417B2 (ja) 2012-05-31 2017-05-10 学校法人近畿大学 抗癌剤に起因する末梢性神経障害性疼痛の予防及び／又は治療剤
WO2017106803A1 (fr) 2015-12-17 2017-06-22 Bioelectron Technology Corporation Dérivés fluoroalkyle, fluoroalcoxy, phénoxy, hétéroaryloxy, alcoxy, et amine 1,4-benzoquinone pour le traitement de troubles du stress oxydatif
US11497795B2 (en) 2018-09-28 2022-11-15 Asahi Kasei Pharma Corporation Medicament for mitigating conditions and/or suppressing onset of peripheral neuropathy induced by anti-malignant tumor agent

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5517769B2 (fr) * 1972-01-10 1980-05-14
US4386078A (en) * 1980-03-03 1983-05-31 The Ohio State University Research Foundation Therapeutic agents for preventing phospholipid degradation and free fatty acid proliferation
IT1207106B (it) * 1980-04-18 1989-05-17 Made Italiana Srl Ora Searle I Preparazione farmaceutica contenente citidin disfofocolina assorbibile per via orale
JPS6043078B2 (ja) * 1980-10-31 1985-09-26 株式会社興人 シチジンジリン酸コリンの製法
JPS6043079B2 (ja) * 1980-12-25 1985-09-26 株式会社興人 シチジン二リン酸コリンの製造方法
JPS57108099A (en) * 1980-12-25 1982-07-05 Kohjin Co Ltd Preparation of choline cytidine diphosphate

Also Published As

Publication number Publication date
US5872108A (en) 1999-02-16
US5801160A (en) 1998-09-01
IN182555B (fr) 1999-05-01
KR19980702724A (ko) 1998-08-05
ZA961791B (en) 1996-09-10

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