IL145790A0 - Methods and reagents for determining enzyme substrate specificity, and uses related thereto - Google Patents

Methods and reagents for determining enzyme substrate specificity, and uses related thereto

Info

Publication number
IL145790A0
IL145790A0 IL14579000A IL14579000A IL145790A0 IL 145790 A0 IL145790 A0 IL 145790A0 IL 14579000 A IL14579000 A IL 14579000A IL 14579000 A IL14579000 A IL 14579000A IL 145790 A0 IL145790 A0 IL 145790A0
Authority
IL
Israel
Prior art keywords
enzyme
peptides
bound
substrate specificity
reagents
Prior art date
Application number
IL14579000A
Other languages
English (en)
Original Assignee
Tufts College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tufts College filed Critical Tufts College
Publication of IL145790A0 publication Critical patent/IL145790A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/42—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL14579000A 1999-04-09 2000-04-10 Methods and reagents for determining enzyme substrate specificity, and uses related thereto IL145790A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12847199P 1999-04-09 1999-04-09
PCT/US2000/009497 WO2000061789A1 (en) 1999-04-09 2000-04-10 Methods and reagents for determining enzyme substrate specificity, and uses related thereto

Publications (1)

Publication Number Publication Date
IL145790A0 true IL145790A0 (en) 2002-07-25

Family

ID=22435532

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14579000A IL145790A0 (en) 1999-04-09 2000-04-10 Methods and reagents for determining enzyme substrate specificity, and uses related thereto

Country Status (9)

Country Link
EP (1) EP1169470B1 (de)
JP (1) JP2002541817A (de)
AT (1) ATE269907T1 (de)
AU (1) AU775164B2 (de)
CA (1) CA2366671A1 (de)
DE (1) DE60011756T2 (de)
ES (1) ES2219333T3 (de)
IL (1) IL145790A0 (de)
WO (1) WO2000061789A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002038796A2 (en) * 2000-11-08 2002-05-16 Beth Israel Deaconess Medical Center, Inc. Methods for determining protease cleavage site motifs
US7727964B2 (en) 2001-11-26 2010-06-01 Trustees Of Tufts College Peptidomimetic inhibitors of post-proline cleaving enzymes
US7261742B2 (en) 2005-10-13 2007-08-28 S.C. Johnson & Son, Inc. Method of deodorizing a textile
CA2699829A1 (en) 2007-09-20 2009-07-02 Arizona Board Of Regents Acting For And On Behalf Of Arizona State Unive Rsity Immobilizing an entity in a desired orientation on a support material
EP2248821B8 (de) 2008-02-22 2015-03-18 Wako Pure Chemical Industries, Ltd. Substrat zur überprüfung von beta-glucan und/oder endotoxinen und entsprechendes prüfverfahren

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991017762A1 (en) * 1990-05-24 1991-11-28 The United States Of America, Represented By The Secretary, United States Department Of Commerce Selective retroviral proteinase inhibitor
US5571681A (en) * 1994-03-10 1996-11-05 The Scripps Research Institute Chemical event selection by suicide substrate conjugates
GB9619168D0 (en) * 1996-09-13 1996-10-23 Univ Cambridge Tech Assay

Also Published As

Publication number Publication date
DE60011756D1 (de) 2004-07-29
DE60011756T2 (de) 2005-07-14
ATE269907T1 (de) 2004-07-15
EP1169470A1 (de) 2002-01-09
EP1169470B1 (de) 2004-06-23
CA2366671A1 (en) 2000-10-19
WO2000061789A1 (en) 2000-10-19
JP2002541817A (ja) 2002-12-10
AU775164B2 (en) 2004-07-22
AU4222600A (en) 2000-11-14
ES2219333T3 (es) 2004-12-01

Similar Documents

Publication Publication Date Title
Watterson et al. The complete amino acid sequence of the Ca2+-dependent modulator protein (calmodulin) of bovine brain.
Neurath The activation of zymogens
Knisatschek et al. Characterization of “thyroliberin-deamidating enzyme” as a post-proline-cleaving enzyme. Partial purification and enzyme-chemical analysis of the enzyme from anterior pituitary tissue.
Fruton Specificity and mechanism of pepsin action
Yang et al. Rubiscolin, a δ selective opioid peptide derived from plant Rubisco
WO2001000663A3 (en) Catalytically active recombinant memapsin and methods of use thereof
WO1995018823A3 (en) Substrate specificity of protein kinases
WO2003074992A3 (en) Phosphorylated proteins and uses related thereto
EP0387231A3 (de) Hemmer der Proteasen von Retroviren
Kruger et al. Inhibition of the Staphylococcus aureus sortase transpeptidase SrtA by phosphinic peptidomimetics
Roy et al. Pyridoxamine-amino acid chimeras in semisynthetic aminotransferase mimics.
Yuan et al. A rationale for the design of an inhibitor of tyrosyl kinase.
WO2002053594A3 (en) Inhibitors of memapsin 2 and use thereof
ATE223971T1 (de) Neue methoden zum auffinden von liganden- und ziel-biomolekülen
IL145790A0 (en) Methods and reagents for determining enzyme substrate specificity, and uses related thereto
YIN et al. Pseudomonas 3β‐hydroxysteroid dehydrogenase: Primary structure and relationships to other steroid dehydrogenases
Furet et al. Modeling of the binding mode of a non-covalent inhibitor of the 20S proteasome. Application to structure-based analogue design
EP1367121A3 (de) Prozess zur Immobilisierung von Polypeptiden über die Carboxylgruppe des C-terminus
Nemerson et al. Peptidase activity associated with the tissue factor of blood coagulation
Moore et al. Peptide hydroxamic acids inhibit skin collagenase
Laki et al. The mode of action of thrombin
WO2002037121A3 (en) Detection of modified amino acids by mass spectrometry
WO2008146259A3 (en) Malt1 specific cleavage in assay and screening method
WO2000056864A3 (en) Methods for altering substrate specificity of phosphoinositide-dependent-protein kinase 1 (pdk1)
AU2957099A (en) Novel physiologically active peptides and utilization thereof