IL139203A0 - Spla2 inhibitor ester - Google Patents
Spla2 inhibitor esterInfo
- Publication number
- IL139203A0 IL139203A0 IL13920399A IL13920399A IL139203A0 IL 139203 A0 IL139203 A0 IL 139203A0 IL 13920399 A IL13920399 A IL 13920399A IL 13920399 A IL13920399 A IL 13920399A IL 139203 A0 IL139203 A0 IL 139203A0
- Authority
- IL
- Israel
- Prior art keywords
- spla2 inhibitor
- inhibitor ester
- ester
- compound
- spla2
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/22—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an aralkyl radical attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8387398P | 1998-05-01 | 1998-05-01 | |
PCT/US1999/008538 WO1999056752A1 (fr) | 1998-05-01 | 1999-04-20 | ESTER INHIBITEUR DE sPLA¿2? |
Publications (1)
Publication Number | Publication Date |
---|---|
IL139203A0 true IL139203A0 (en) | 2001-11-25 |
Family
ID=22181214
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL13920399A IL139203A0 (en) | 1998-05-01 | 1999-04-20 | Spla2 inhibitor ester |
Country Status (22)
Country | Link |
---|---|
EP (1) | EP1073440B1 (fr) |
JP (1) | JP4459441B2 (fr) |
KR (1) | KR20010071197A (fr) |
CN (1) | CN1303290A (fr) |
AT (1) | ATE280155T1 (fr) |
AU (1) | AU755901B2 (fr) |
BR (1) | BR9910149A (fr) |
CA (1) | CA2331036A1 (fr) |
DE (1) | DE69921314T2 (fr) |
EA (1) | EA003277B1 (fr) |
ES (1) | ES2230847T3 (fr) |
HR (1) | HRP20000738A2 (fr) |
HU (1) | HUP0201636A1 (fr) |
ID (1) | ID27812A (fr) |
IL (1) | IL139203A0 (fr) |
NO (1) | NO315940B1 (fr) |
NZ (1) | NZ507391A (fr) |
PL (1) | PL344571A1 (fr) |
SK (1) | SK16332000A3 (fr) |
TR (1) | TR200003198T2 (fr) |
WO (1) | WO1999056752A1 (fr) |
ZA (1) | ZA200005561B (fr) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6140327A (en) * | 1999-05-12 | 2000-10-31 | Eli Lilly And Company | Morpholino-n-ethyl ester derivative of an indole sPLA2 inhibitor |
AU2252201A (en) * | 1999-12-16 | 2001-06-25 | Eli Lilly And Company | Carbon monoxide-based synthesis of spla2 inhibitors |
DE19962300A1 (de) * | 1999-12-23 | 2001-06-28 | Asta Medica Ag | Substituierte N-Benzyl-Indol-3-yl-glyoxylsäure-Derivate mit Antitumorwirkung |
AU2001272915A1 (en) * | 2000-07-14 | 2002-01-30 | Eli Lilly And Company | Method for treating sepsis |
US8048880B2 (en) | 2007-05-03 | 2011-11-01 | Anthera Pharmaceuticals, Inc. | Treatment of cardiovascular disease and dyslipidemia using secretory phospholipase A2 (SPLA2) inhibitors and SPLA2 inhibitor combination therapies |
EP2154958A4 (fr) * | 2007-05-03 | 2011-05-04 | Anthera Pharmaceuticals Inc | Traitement des maladies cardiovasculaires et de la dyslipidémie au moyen d'inhibiteurs de la phospholipase a<sb>2</sb>sécrétoire (spla<sb>2</sb>) et thérapies combinées impliquant des inhibiteurs de la spla<sb>2</sb> |
US20150335498A1 (en) * | 2014-05-22 | 2015-11-26 | The Procter & Gamble Company | Heterogenous mass containing foam |
US10729600B2 (en) | 2015-06-30 | 2020-08-04 | The Procter & Gamble Company | Absorbent structure |
MX2018005609A (es) | 2015-11-04 | 2018-11-09 | Procter & Gamble | Estructura absorbente. |
CN108348387B (zh) | 2015-11-04 | 2021-05-28 | 宝洁公司 | 吸收结构 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2036307C (fr) * | 1990-03-08 | 2002-07-09 | Susan Jean Ward | Compositions anti-glaucome, a base de 3-arylcarbonyl-1-aminoalkyl-1h-indole; methode d'utilisation |
TW383302B (en) * | 1994-04-01 | 2000-03-01 | Lilly Co Eli | 1H-indole-3-glyoxylamide sPLA2 inhibitors |
DE4435477A1 (de) * | 1994-10-04 | 1996-04-11 | Bayer Ag | Cycloalkano-indol- und -azaindol-derivate |
JP3068200B2 (ja) * | 1995-06-06 | 2000-07-24 | ファイザー・インコーポレーテッド | グリコーゲンホスホリラーゼ阻害剤としての置換n−(インドール−2−カルボニル−)アミドおよび誘導体 |
WO2000037022A2 (fr) * | 1998-12-21 | 2000-06-29 | Eli Lilly And Company | Polytherapie destinee au traitement de la septicemie |
-
1999
- 1999-04-20 EA EA200001141A patent/EA003277B1/ru not_active IP Right Cessation
- 1999-04-20 AT AT99918666T patent/ATE280155T1/de not_active IP Right Cessation
- 1999-04-20 WO PCT/US1999/008538 patent/WO1999056752A1/fr not_active Application Discontinuation
- 1999-04-20 EP EP99918666A patent/EP1073440B1/fr not_active Expired - Lifetime
- 1999-04-20 CA CA002331036A patent/CA2331036A1/fr not_active Abandoned
- 1999-04-20 ES ES99918666T patent/ES2230847T3/es not_active Expired - Lifetime
- 1999-04-20 IL IL13920399A patent/IL139203A0/xx unknown
- 1999-04-20 TR TR2000/03198T patent/TR200003198T2/xx unknown
- 1999-04-20 SK SK1633-2000A patent/SK16332000A3/sk unknown
- 1999-04-20 KR KR1020007012114A patent/KR20010071197A/ko not_active Application Discontinuation
- 1999-04-20 BR BR9910149-1A patent/BR9910149A/pt not_active IP Right Cessation
- 1999-04-20 JP JP2000546777A patent/JP4459441B2/ja not_active Expired - Fee Related
- 1999-04-20 PL PL99344571A patent/PL344571A1/xx not_active IP Right Cessation
- 1999-04-20 AU AU36525/99A patent/AU755901B2/en not_active Ceased
- 1999-04-20 HU HU0201636A patent/HUP0201636A1/hu unknown
- 1999-04-20 CN CN99805672A patent/CN1303290A/zh active Pending
- 1999-04-20 DE DE69921314T patent/DE69921314T2/de not_active Expired - Lifetime
- 1999-04-20 ID IDW20002216A patent/ID27812A/id unknown
- 1999-04-20 NZ NZ507391A patent/NZ507391A/en unknown
-
2000
- 2000-10-10 ZA ZA200005561A patent/ZA200005561B/en unknown
- 2000-10-31 HR HR20000738A patent/HRP20000738A2/hr not_active Application Discontinuation
- 2000-10-31 NO NO20005477A patent/NO315940B1/no not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EA003277B1 (ru) | 2003-04-24 |
NO20005477D0 (no) | 2000-10-31 |
NO315940B1 (no) | 2003-11-17 |
AU3652599A (en) | 1999-11-23 |
DE69921314D1 (de) | 2004-11-25 |
WO1999056752A1 (fr) | 1999-11-11 |
AU755901B2 (en) | 2003-01-02 |
NZ507391A (en) | 2003-12-19 |
EA200001141A1 (ru) | 2001-04-23 |
CN1303290A (zh) | 2001-07-11 |
DE69921314T2 (de) | 2006-02-09 |
ZA200005561B (en) | 2002-01-10 |
CA2331036A1 (fr) | 1999-11-11 |
BR9910149A (pt) | 2001-10-02 |
TR200003198T2 (tr) | 2001-03-21 |
SK16332000A3 (sk) | 2001-06-11 |
HRP20000738A2 (en) | 2001-10-31 |
JP4459441B2 (ja) | 2010-04-28 |
NO20005477L (no) | 2000-10-31 |
PL344571A1 (en) | 2001-11-05 |
EP1073440A4 (fr) | 2002-07-17 |
JP2002513761A (ja) | 2002-05-14 |
EP1073440B1 (fr) | 2004-10-20 |
HUP0201636A1 (en) | 2002-09-28 |
ES2230847T3 (es) | 2005-05-01 |
KR20010071197A (ko) | 2001-07-28 |
ID27812A (id) | 2001-04-26 |
EP1073440A1 (fr) | 2001-02-07 |
ATE280155T1 (de) | 2004-11-15 |
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