IL137765A0 - Combination of a nucleic acid and a vasoactive agent for enhanced gene delivery - Google Patents

Combination of a nucleic acid and a vasoactive agent for enhanced gene delivery

Info

Publication number
IL137765A0
IL137765A0 IL13776599A IL13776599A IL137765A0 IL 137765 A0 IL137765 A0 IL 137765A0 IL 13776599 A IL13776599 A IL 13776599A IL 13776599 A IL13776599 A IL 13776599A IL 137765 A0 IL137765 A0 IL 137765A0
Authority
IL
Israel
Prior art keywords
combination
nucleic acid
gene delivery
vasoactive agent
enhanced gene
Prior art date
Application number
IL13776599A
Other languages
English (en)
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Publication of IL137765A0 publication Critical patent/IL137765A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/0075—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the delivery route, e.g. oral, subcutaneous
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/0083—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the administration regime
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Paints Or Removers (AREA)
IL13776599A 1998-02-11 1999-02-09 Combination of a nucleic acid and a vasoactive agent for enhanced gene delivery IL137765A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2177398A 1998-02-11 1998-02-11
PCT/US1999/002702 WO1999040945A2 (en) 1998-02-11 1999-02-09 Combination of a nucleic acid and a vasoactive agent for enhanced gene delivery

Publications (1)

Publication Number Publication Date
IL137765A0 true IL137765A0 (en) 2001-10-31

Family

ID=21806073

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13776599A IL137765A0 (en) 1998-02-11 1999-02-09 Combination of a nucleic acid and a vasoactive agent for enhanced gene delivery

Country Status (11)

Country Link
EP (2) EP1053025A2 (zh)
JP (1) JP2002502885A (zh)
KR (1) KR20010015915A (zh)
CN (2) CN101186928A (zh)
AU (1) AU2663799A (zh)
CA (1) CA2320302A1 (zh)
EA (1) EA019099B1 (zh)
IL (1) IL137765A0 (zh)
NZ (1) NZ545047A (zh)
WO (1) WO1999040945A2 (zh)
ZA (1) ZA991102B (zh)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6752987B1 (en) 1995-02-28 2004-06-22 The Regents Of The University Of California Adenovirus encoding human adenylylcyclase (AC) VI
DE69939484D1 (de) 1998-10-28 2008-10-16 Cornell Res Foundation Inc Methoden zur regulierung der angiogenese und vaskuläre integrität mittels trk rezeptor liganden bdnf, nt-3 und nt-4
CN1433325A (zh) * 1999-11-05 2003-07-30 加利福尼亚大学董事会 通过体内基因递送治疗心血管疾病的技术和组合物
WO2001048164A2 (en) 1999-12-27 2001-07-05 The Regents Of The University Of California Modified adenylylcyclase type vi useful in gene therapy for congestive heart failure
AU2002216751A1 (en) * 2000-06-30 2002-01-14 Collateral Therapeutics, Inc. Dual recombinant gene therapy compositions and methods of use
JP2005052001A (ja) * 2001-07-05 2005-03-03 Takara Bio Inc 遺伝子治療剤
EP2236153A3 (en) 2005-01-25 2012-08-22 Five Prime Therapeutics, Inc. Compositons and methods for treating cardiac conditions
AU2007277392A1 (en) * 2006-07-25 2008-01-31 Celladon Corporation Extended antegrade epicardial coronary infusion of adeno-associated viral vectors for gene therapy
EP2173425B1 (en) 2007-07-18 2012-11-21 Silk Road Medical, Inc. Systems for establishing retrograde carotid arterial blood flow
AU2008350903B2 (en) 2008-02-19 2015-04-02 Celladon Corporation Compositions for enhanced uptake of viral vectors in the myocardium
US20130096500A1 (en) * 2011-07-07 2013-04-18 Gabor Rubanyi Nucleic acid based cardiovascular therapeutics
WO2014160887A2 (en) * 2013-03-28 2014-10-02 Silk Road Medical, Inc. Methods and systems for establishing retrograde carotid arterial blood flow
WO2019089385A1 (en) 2017-11-02 2019-05-09 Silk Road Medical, Inc. Fenestrated sheath for embolic protection during transcarotid carotid artery revascularization

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA001616B1 (ru) * 1995-02-28 2001-06-25 Зе Риджентс Оф Зи Юнивесити Оф Кэлифоньэ Способ лечения болезни сердца, способ лечения недостаточности периферических сосудов и способ ограничения доставки и экспрессии трансгенной конструкции в определенном органе или структуре
US5869230A (en) * 1995-03-30 1999-02-09 Beth Israel Hospital Association Gene transfer into the kidney
AU9449598A (en) * 1997-10-08 1999-04-27 Cobra Therapeutics Limited Use of a vasoactive compound in the enhancement of gene delivery
US6376471B1 (en) * 1997-10-10 2002-04-23 Johns Hopkins University Gene delivery compositions and methods

Also Published As

Publication number Publication date
WO1999040945A3 (en) 1999-09-30
EA200000828A1 (ru) 2001-02-26
WO1999040945A2 (en) 1999-08-19
EA019099B1 (ru) 2014-01-30
EP1695719A1 (en) 2006-08-30
AU2663799A (en) 1999-08-30
ZA991102B (en) 2000-03-31
CN100350979C (zh) 2007-11-28
NZ545047A (en) 2009-05-31
KR20010015915A (ko) 2001-02-26
JP2002502885A (ja) 2002-01-29
CA2320302A1 (en) 1999-08-19
EP1053025A2 (en) 2000-11-22
CN101186928A (zh) 2008-05-28
CN1301181A (zh) 2001-06-27

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