IL135399A0 - A process for the preparation of aminocarbonyl derivatives of geneseroline having selective brain anticholinesterase activity - Google Patents
A process for the preparation of aminocarbonyl derivatives of geneseroline having selective brain anticholinesterase activityInfo
- Publication number
- IL135399A0 IL135399A0 IL13539998A IL13539998A IL135399A0 IL 135399 A0 IL135399 A0 IL 135399A0 IL 13539998 A IL13539998 A IL 13539998A IL 13539998 A IL13539998 A IL 13539998A IL 135399 A0 IL135399 A0 IL 135399A0
- Authority
- IL
- Israel
- Prior art keywords
- geneseroline
- preparation
- selective brain
- anticholinesterase activity
- aminocarbonyl derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT002299 IT1295309B1 (it) | 1997-10-10 | 1997-10-10 | Procedimento per la preparazione di amminocarbonil derivati di geneserolina |
| IT002300 IT1295310B1 (it) | 1997-10-10 | 1997-10-10 | Amminocarbonil derivati di geneserolina ad attivita' anticolinesterasica selettiva a livello cerebrale |
| PCT/EP1998/006377 WO1999019329A1 (fr) | 1997-10-10 | 1998-10-07 | Procede de preparation de derives aminocarbonyle de geneseroline ayant une activite anticolinesterase selective dans le cerveau |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL135399A0 true IL135399A0 (en) | 2001-05-20 |
Family
ID=26331547
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13539998A IL135399A0 (en) | 1997-10-10 | 1998-10-07 | A process for the preparation of aminocarbonyl derivatives of geneseroline having selective brain anticholinesterase activity |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US6297237B1 (fr) |
| EP (1) | EP1023297A1 (fr) |
| KR (1) | KR20010015714A (fr) |
| CN (1) | CN1278264A (fr) |
| AR (1) | AR018511A1 (fr) |
| AU (1) | AU750964B2 (fr) |
| BR (1) | BR9815237A (fr) |
| CA (1) | CA2274658A1 (fr) |
| EA (1) | EA003192B1 (fr) |
| HU (1) | HUP0003747A3 (fr) |
| IL (1) | IL135399A0 (fr) |
| NZ (1) | NZ503773A (fr) |
| PL (1) | PL339761A1 (fr) |
| SK (1) | SK5032000A3 (fr) |
| TR (1) | TR200000951T2 (fr) |
| TW (1) | TW490467B (fr) |
| WO (1) | WO1999019329A1 (fr) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1109003B (it) * | 1977-09-20 | 1985-12-16 | Univ Firenze | Derivati dell 1 2 3 8 3 a 8 a esai dropirrolo 23 b indolo |
| US4791107A (en) * | 1986-07-16 | 1988-12-13 | Hoechst-Roussel Pharmaceuticals, Inc. | Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use |
| IT1251166B (it) * | 1991-08-09 | 1995-05-04 | Chiesi Farma Spa | Derivati di geneserina,loro preparazione e composizioni farmaceutiche che li contengono |
| US5571929A (en) * | 1994-12-07 | 1996-11-05 | The United States Of America As Represented By The Department Of Health And Human Services | Resolution and reduction of physostigmine intermediates and derivatives |
| US5677457A (en) * | 1996-12-19 | 1997-10-14 | Hoechst Marion Roussel, Inc. | Method of preparation of physostigmine carbamate derivatives from eseroline ethers |
-
1998
- 1998-10-07 WO PCT/EP1998/006377 patent/WO1999019329A1/fr not_active Application Discontinuation
- 1998-10-07 HU HU0003747A patent/HUP0003747A3/hu unknown
- 1998-10-07 EP EP98954370A patent/EP1023297A1/fr not_active Withdrawn
- 1998-10-07 BR BR9815237-8A patent/BR9815237A/pt not_active IP Right Cessation
- 1998-10-07 KR KR1020007003805A patent/KR20010015714A/ko not_active Application Discontinuation
- 1998-10-07 CA CA002274658A patent/CA2274658A1/fr not_active Abandoned
- 1998-10-07 CN CN98810683A patent/CN1278264A/zh active Pending
- 1998-10-07 SK SK503-2000A patent/SK5032000A3/sk unknown
- 1998-10-07 AU AU11516/99A patent/AU750964B2/en not_active Ceased
- 1998-10-07 IL IL13539998A patent/IL135399A0/xx unknown
- 1998-10-07 TR TR2000/00951T patent/TR200000951T2/xx unknown
- 1998-10-07 US US09/319,693 patent/US6297237B1/en not_active Expired - Fee Related
- 1998-10-07 EA EA200000300A patent/EA003192B1/ru not_active IP Right Cessation
- 1998-10-07 NZ NZ503773A patent/NZ503773A/en unknown
- 1998-10-07 PL PL98339761A patent/PL339761A1/xx unknown
- 1998-10-09 AR ARP980105062A patent/AR018511A1/es unknown
- 1998-10-23 TW TW087117571A patent/TW490467B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| TW490467B (en) | 2002-06-11 |
| HUP0003747A2 (hu) | 2001-10-28 |
| TR200000951T2 (tr) | 2000-07-21 |
| NZ503773A (en) | 2002-05-31 |
| EA003192B1 (ru) | 2003-02-27 |
| AU750964B2 (en) | 2002-08-01 |
| CN1278264A (zh) | 2000-12-27 |
| EA200000300A1 (ru) | 2000-12-25 |
| SK5032000A3 (en) | 2000-10-09 |
| PL339761A1 (en) | 2001-01-02 |
| US6297237B1 (en) | 2001-10-02 |
| EP1023297A1 (fr) | 2000-08-02 |
| BR9815237A (pt) | 2000-10-31 |
| CA2274658A1 (fr) | 1999-04-22 |
| AR018511A1 (es) | 2001-11-28 |
| KR20010015714A (ko) | 2001-02-26 |
| AU1151699A (en) | 1999-05-03 |
| WO1999019329A1 (fr) | 1999-04-22 |
| HUP0003747A3 (en) | 2001-12-28 |
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