IL134602A0 - Conjugates that contain the homeodomain of antennapedia - Google Patents
Conjugates that contain the homeodomain of antennapediaInfo
- Publication number
- IL134602A0 IL134602A0 IL13460298A IL13460298A IL134602A0 IL 134602 A0 IL134602 A0 IL 134602A0 IL 13460298 A IL13460298 A IL 13460298A IL 13460298 A IL13460298 A IL 13460298A IL 134602 A0 IL134602 A0 IL 134602A0
- Authority
- IL
- Israel
- Prior art keywords
- antennapedia
- homeodomain
- conjugates
- contain
- Prior art date
Links
- 108700031308 Antennapedia Homeodomain Proteins 0.000 title 1
- 108010048671 Homeodomain Proteins Proteins 0.000 title 1
- 102000009331 Homeodomain Proteins Human genes 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
- C07K14/43577—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from flies
- C07K14/43581—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from flies from Drosophila
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Insects & Arthropods (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Variable-Direction Aerials And Aerial Arrays (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9718609.2A GB9718609D0 (en) | 1997-09-02 | 1997-09-02 | Fusion protein |
| PCT/GB1998/002628 WO1999011809A1 (fr) | 1997-09-02 | 1998-09-02 | Conjugues renfermant l'homeodomaine de l'antennapedia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL134602A0 true IL134602A0 (en) | 2001-04-30 |
Family
ID=10818419
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13460298A IL134602A0 (en) | 1997-09-02 | 1998-09-02 | Conjugates that contain the homeodomain of antennapedia |
| IL134602A IL134602A (en) | 1997-09-02 | 2000-02-17 | Conjugates that contain the homeodomain of antennapedia |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL134602A IL134602A (en) | 1997-09-02 | 2000-02-17 | Conjugates that contain the homeodomain of antennapedia |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US7968512B2 (fr) |
| EP (1) | EP1009847A1 (fr) |
| JP (1) | JP2001514858A (fr) |
| AU (1) | AU737829B2 (fr) |
| BR (1) | BR9811744A (fr) |
| CA (1) | CA2301157A1 (fr) |
| GB (1) | GB9718609D0 (fr) |
| IL (2) | IL134602A0 (fr) |
| NZ (1) | NZ503007A (fr) |
| WO (1) | WO1999011809A1 (fr) |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU721121B2 (en) * | 1996-12-02 | 2000-06-22 | Wake Forest University | Inactivation of HIV co-receptors as therapy for HIV infection |
| US6221355B1 (en) * | 1997-12-10 | 2001-04-24 | Washington University | Anti-pathogen system and methods of use thereof |
| GB9814527D0 (en) * | 1998-07-03 | 1998-09-02 | Cyclacel Ltd | Delivery system |
| WO2000027795A1 (fr) | 1998-11-12 | 2000-05-18 | Invitrogen Corporation | Reactifs de transfection |
| HUP0204199A3 (en) | 1998-11-13 | 2005-09-28 | Cyclacel Ltd | Transport vectors |
| AU762006B2 (en) * | 1998-12-24 | 2003-06-19 | Ucb | Peptidic product, process and composition |
| JP2002539839A (ja) * | 1999-03-31 | 2002-11-26 | インヴィトロゲン・コーポレーション | 転位ポリペプチドによる機能性タンパク質配列の送達 |
| US6773920B1 (en) | 1999-03-31 | 2004-08-10 | Invitrogen Corporation | Delivery of functional protein sequences by translocating polypeptides |
| US6372494B1 (en) | 1999-05-14 | 2002-04-16 | Advanced Tissue Sciences, Inc. | Methods of making conditioned cell culture medium compositions |
| EP1118668A1 (fr) * | 2000-01-07 | 2001-07-25 | ARTEMIS Pharmaceuticals GmbH | Transduction d'une recombinase pour le ciblage inductible de gènes |
| WO2001049832A2 (fr) * | 2000-01-07 | 2001-07-12 | Artemis Pharmaceuticals Gmbh | Transduction de recombinases pour ciblage genetique inductible |
| GB0003284D0 (en) * | 2000-02-15 | 2000-04-05 | Secr Defence Brit | Anti-viral therapy |
| EP1272221A2 (fr) * | 2000-04-12 | 2003-01-08 | Implyx Ltd. | Conjugues de peptides utilises pour l'apport de medicament |
| DE10027777A1 (de) * | 2000-06-07 | 2001-12-13 | Otogene Ag | Transfektionsverfahren |
| GB0015090D0 (en) * | 2000-06-20 | 2000-08-09 | Implyx Ltd | Gene-activating conjugates |
| KR100374050B1 (ko) * | 2000-07-26 | 2003-03-03 | 최수영 | 세포침투성 융합단백질, 이를 코딩하는 재조합폴리뉴클레오타이드 및 발현벡터 |
| US20030027335A1 (en) * | 2000-09-07 | 2003-02-06 | Ruley H. Earl | Genome engineering by cell-permeable DNA site-specific recombinases |
| US6472176B2 (en) * | 2000-12-14 | 2002-10-29 | Genvec, Inc. | Polynucleotide encoding chimeric protein and related vector, cell, and method of expression thereof |
| US7442686B2 (en) | 2001-04-12 | 2008-10-28 | Bioaxone Therapeutique Inc. | Treatment of macular degeneration with ADP-ribosyl transferase fusion protein therapeutic compositions |
| CA2367636C (fr) | 2001-04-12 | 2010-05-04 | Lisa Mckerracher | Proteines de fusion |
| EP1406573A4 (fr) * | 2001-06-07 | 2005-03-30 | Skinmedica Inc | Milieu de culture cellulaire conditionne et utilisations de ce milieu |
| GB0124391D0 (en) * | 2001-10-11 | 2001-11-28 | Gene Expression Technologies L | Control of gene expression |
| US20050136040A1 (en) * | 2001-10-11 | 2005-06-23 | Imperial College Innovations Limited | Control of gene expression using a complex of an oligonucleotide and a regulatory peptide |
| ITRM20030376A1 (it) | 2003-07-31 | 2005-02-01 | Univ Roma | Procedimento per l'isolamento e l'espansione di cellule staminali cardiache da biopsia. |
| US11660317B2 (en) | 2004-11-08 | 2023-05-30 | The Johns Hopkins University | Compositions comprising cardiosphere-derived cells for use in cell therapy |
| DE102007041655A1 (de) | 2007-09-03 | 2009-03-05 | Medicyte Gmbh | Vermehrung von primären Zellen und deren Verwendung |
| US8119366B2 (en) | 2007-10-05 | 2012-02-21 | Trojan Technologies, Ltd. | Antennapedia-dominant negative mastermind-like construct |
| CN102459329A (zh) * | 2009-04-14 | 2012-05-16 | 特洛伊科技有限公司 | 治疗性触角足-抗体分子及其使用方法 |
| US9845457B2 (en) | 2010-04-30 | 2017-12-19 | Cedars-Sinai Medical Center | Maintenance of genomic stability in cultured stem cells |
| DE102010041958A1 (de) | 2010-10-04 | 2012-04-05 | Medicyte Gmbh | Geeignete Hepatozyten für in-vitro Genotoxitätstests |
| US20140296154A1 (en) * | 2011-05-06 | 2014-10-02 | Yale University | Method of preventing development of psoriatic lesions |
| US9248198B2 (en) * | 2011-06-13 | 2016-02-02 | The Board Of Trustees Of The University Of Illinois | Peptide compositions and methods for treating lung injury, asthma, anaphylaxis, angioedema, systemic vascular permeability syndromes, and nasal congestion |
| AU2013246034B2 (en) | 2012-04-09 | 2017-12-07 | Case Western Reserve University | Compositions and methods for inhibiting the activity of LAR family phosphatases |
| US9884076B2 (en) | 2012-06-05 | 2018-02-06 | Capricor, Inc. | Optimized methods for generation of cardiac stem cells from cardiac tissue and their use in cardiac therapy |
| US9828603B2 (en) | 2012-08-13 | 2017-11-28 | Cedars Sinai Medical Center | Exosomes and micro-ribonucleic acids for tissue regeneration |
| DK3581207T3 (da) | 2013-06-11 | 2023-02-06 | Ppl Bvi Ltd | Fusionsproteiner omfattende hoxd12 og nemo-bindingsdomæne og anvendelse deraf |
| EP2927685A1 (fr) | 2014-04-02 | 2015-10-07 | Medicyte GmbH | Suitable Hepatocytes for in-vitro Hepatitis Tests |
| EP3169310A1 (fr) | 2014-07-15 | 2017-05-24 | Life Technologies Corporation | Compositions comprenant des agrégats lipidiques et procédés d'administration efficace de molécules dans des cellules |
| CA2962444C (fr) | 2014-10-03 | 2023-09-05 | Cedars-Sinai Medical Center | Cellules derivees de la cardiosphere et exosomes secretes par ces cellules dans le traitement d'une dystrophie musculaire |
| BR112017018665A2 (pt) | 2015-03-02 | 2018-04-24 | The Board Of Trustees Of The University Of Illinois | peptídeos para inibição de angiogênese |
| WO2017123662A1 (fr) | 2016-01-11 | 2017-07-20 | Cedars-Sinai Medical Center | Cellules dérivées de cardiosphères et exosomes sécrétés par ces cellules dans le traitement d'une insuffisance cardiaque à fraction d'éjection préservée |
| KR20180132807A (ko) | 2016-04-07 | 2018-12-12 | 케이스 웨스턴 리저브 유니버시티 | 신경퇴행성 질환의 치료용 tdp-43 미토콘드리아 국소화 억제제 |
| WO2017210652A1 (fr) | 2016-06-03 | 2017-12-07 | Cedars-Sinai Medical Center | Exosomes dérivés de cdc pour le traitement des tachyarythmies ventriculaires |
| US11541078B2 (en) | 2016-09-20 | 2023-01-03 | Cedars-Sinai Medical Center | Cardiosphere-derived cells and their extracellular vesicles to retard or reverse aging and age-related disorders |
| WO2018195210A1 (fr) | 2017-04-19 | 2018-10-25 | Cedars-Sinai Medical Center | Méthodes et compositions pour traiter une dystrophie musculaire squelettique |
| WO2019126068A1 (fr) | 2017-12-20 | 2019-06-27 | Cedars-Sinai Medical Center | Vésicules extracellulaires modifiées pour une administration tissulaire améliorée |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2739621B1 (fr) * | 1995-10-05 | 1997-12-05 | Centre Nat Rech Scient | Peptides utilisables comme vecteurs pour l'adressage intracellulaire de molecules actives |
-
1997
- 1997-09-02 GB GBGB9718609.2A patent/GB9718609D0/en active Pending
-
1998
- 1998-09-02 WO PCT/GB1998/002628 patent/WO1999011809A1/fr not_active Application Discontinuation
- 1998-09-02 NZ NZ503007A patent/NZ503007A/xx not_active IP Right Cessation
- 1998-09-02 EP EP98940453A patent/EP1009847A1/fr not_active Withdrawn
- 1998-09-02 CA CA002301157A patent/CA2301157A1/fr not_active Abandoned
- 1998-09-02 BR BR9811744-0A patent/BR9811744A/pt not_active Application Discontinuation
- 1998-09-02 JP JP2000508817A patent/JP2001514858A/ja active Pending
- 1998-09-02 AU AU88776/98A patent/AU737829B2/en not_active Ceased
- 1998-09-02 IL IL13460298A patent/IL134602A0/xx active IP Right Grant
-
2000
- 2000-02-17 IL IL134602A patent/IL134602A/en not_active IP Right Cessation
-
2004
- 2004-02-27 US US10/789,403 patent/US7968512B2/en not_active Expired - Lifetime
-
2011
- 2011-06-24 US US13/168,167 patent/US8735340B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU8877698A (en) | 1999-03-22 |
| US8735340B2 (en) | 2014-05-27 |
| JP2001514858A (ja) | 2001-09-18 |
| US20110256168A1 (en) | 2011-10-20 |
| AU737829B2 (en) | 2001-08-30 |
| IL134602A (en) | 2006-10-31 |
| US20080317773A1 (en) | 2008-12-25 |
| GB9718609D0 (en) | 1997-11-05 |
| CA2301157A1 (fr) | 1999-03-11 |
| EP1009847A1 (fr) | 2000-06-21 |
| BR9811744A (pt) | 2002-01-02 |
| WO1999011809A1 (fr) | 1999-03-11 |
| US7968512B2 (en) | 2011-06-28 |
| NZ503007A (en) | 2000-11-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed |