IL131655A0 - Isolation of tissue specific ligands and their use for targeting pharmaceuticals to organs - Google Patents
Isolation of tissue specific ligands and their use for targeting pharmaceuticals to organsInfo
- Publication number
- IL131655A0 IL131655A0 IL13165598A IL13165598A IL131655A0 IL 131655 A0 IL131655 A0 IL 131655A0 IL 13165598 A IL13165598 A IL 13165598A IL 13165598 A IL13165598 A IL 13165598A IL 131655 A0 IL131655 A0 IL 131655A0
- Authority
- IL
- Israel
- Prior art keywords
- organs
- isolation
- tissue specific
- specific ligands
- pharmaceuticals
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US81007497A | 1997-03-04 | 1997-03-04 | |
US3950997P | 1997-03-04 | 1997-03-04 | |
PCT/US1998/004188 WO1998039469A1 (fr) | 1997-03-04 | 1998-03-04 | Isolement de ligands peptidiques a specificite tissulaire et utilisation de ces derniers pour cibler des substances pharmaceutiques sur des organes |
Publications (1)
Publication Number | Publication Date |
---|---|
IL131655A0 true IL131655A0 (en) | 2001-01-28 |
Family
ID=26716199
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL13165598A IL131655A0 (en) | 1997-03-04 | 1998-03-04 | Isolation of tissue specific ligands and their use for targeting pharmaceuticals to organs |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0975792B1 (fr) |
AT (1) | ATE375399T1 (fr) |
AU (1) | AU6682598A (fr) |
CA (1) | CA2283474A1 (fr) |
DE (1) | DE69838544T2 (fr) |
HK (1) | HK1026234A1 (fr) |
IL (1) | IL131655A0 (fr) |
WO (1) | WO1998039469A1 (fr) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9708265D0 (en) * | 1997-04-24 | 1997-06-18 | Nycomed Imaging As | Contrast agents |
JP4528989B2 (ja) * | 1999-03-31 | 2010-08-25 | 学校法人慶應義塾 | インフルエンザウイルス・ヘマグルチニン結合性ペプチド |
GB9912994D0 (en) * | 1999-06-07 | 1999-08-04 | Melvin William T | Fibrin fragments and therapeutic targets |
US6903196B1 (en) | 1999-06-17 | 2005-06-07 | Utah Ventures Ii, L.P. | Methods for identifying and isolating tissue-specific lumen-exposed molecules |
AU781951B2 (en) * | 2000-02-02 | 2005-06-23 | Transgene S.A. | Targeting peptides |
EP1315517B1 (fr) * | 2000-09-04 | 2010-10-20 | Hyo-Joon Kim | Peptides mimetiques pour l'epitope de l'apolipoproteine b-100, concatemeres et ses peptides modifies, et composition de vaccin les comprenant |
US7452964B2 (en) | 2001-09-07 | 2008-11-18 | Board Of Regents, The University Of Texas System | Compositions and methods of use of targeting peptides against placenta and adipose tissues |
US20040170955A1 (en) | 2000-09-08 | 2004-09-02 | Wadih Arap | Human and mouse targeting peptides identified by phage display |
US7420030B2 (en) | 2000-09-08 | 2008-09-02 | The Board Of Regents Of The University Of Texas System | Aminopeptidase A (APA) targeting peptides for the treatment of cancer |
EP1497314A4 (fr) * | 2001-09-07 | 2007-10-10 | Univ Texas | Compositions et procedes d'utilisation de peptides de ciblage contre les tissus adipeux et placentaires |
WO2004060403A2 (fr) | 2003-01-06 | 2004-07-22 | Angiochem Inc. | Methode de transport d'un compose a travers une barriere sang/cerveau |
JP2006101709A (ja) * | 2004-09-30 | 2006-04-20 | Glycomedics Inc | ヘマグルチニン結合ペプチド、インフルエンザウイルス感染阻害剤、リポソーム、インフルエンザ治療薬、インフルエンザ予防薬 |
CN101160403B (zh) | 2005-02-18 | 2014-08-13 | 安吉奥开米公司 | 转运化合物穿过血脑屏障的分子 |
CA2614687C (fr) | 2005-07-15 | 2016-03-22 | Angiochem Inc. | Utilisation de polypeptides de l'aprotinine comme vehicules dans des conjugues pharmaceutiques |
US9365634B2 (en) | 2007-05-29 | 2016-06-14 | Angiochem Inc. | Aprotinin-like polypeptides for delivering agents conjugated thereto to tissues |
CN102026667B (zh) | 2008-04-18 | 2014-06-25 | 安吉奥开米公司 | 紫杉醇、紫杉醇类似物或紫杉醇结合物的药物组合物及相关制备方法和用途 |
JP2012505637A (ja) | 2008-10-15 | 2012-03-08 | アンジオケム,インコーポレーテッド | Glp−1アゴニストのコンジュゲート及びその使用 |
MX2011004019A (es) | 2008-10-15 | 2011-06-24 | Angiochem Inc | Conjugados de etoposido y doxorubicina para entrega de farmacos. |
CA2745524C (fr) | 2008-12-05 | 2020-06-09 | Angiochem Inc. | Conjugues de neurotensine ou d'analogues de neurotensine et leurs applications |
BRPI0922611A2 (pt) | 2008-12-17 | 2018-11-06 | Angiochem Inc | inibidores de metaloproteína de matriz de membrana tipo 1 e usos dos mesmos |
CA2759129C (fr) | 2009-04-20 | 2018-12-11 | Angiochem Inc. | Traitement d'un cancer de l'ovaire a l'aide d'un agent anticancereux conjugue a un analogue d'angiopep-2 |
MX2012000016A (es) | 2009-07-02 | 2012-03-26 | Angiochem Inc | Conjugados de peptidos multimericos y sus usos. |
AU2013302270A1 (en) | 2012-08-14 | 2015-03-26 | Angiochem Inc. | Peptide-dendrimer conjugates and uses thereof |
ES2826827T3 (es) | 2015-06-15 | 2021-05-19 | Angiochem Inc | Métodos para el tratamiento de carcinomatosis leptomeníngea |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5650489A (en) * | 1990-07-02 | 1997-07-22 | The Arizona Board Of Regents | Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof |
WO1994026787A1 (fr) * | 1993-05-07 | 1994-11-24 | The Board Of Trustees Of The Leland Stanford Junior University | Procede pour generer des bibliotheques d'anticorps de phages specifiques de types cellulaires |
WO1997010507A1 (fr) * | 1995-09-11 | 1997-03-20 | La Jolla Cancer Research Foundation | Molecules qui se dirigent vers un organe ou des tissus choisis in vivo et procede d'identification desdites molecules |
-
1998
- 1998-03-04 WO PCT/US1998/004188 patent/WO1998039469A1/fr active IP Right Grant
- 1998-03-04 DE DE69838544T patent/DE69838544T2/de not_active Expired - Fee Related
- 1998-03-04 IL IL13165598A patent/IL131655A0/xx not_active IP Right Cessation
- 1998-03-04 AT AT98908909T patent/ATE375399T1/de not_active IP Right Cessation
- 1998-03-04 AU AU66825/98A patent/AU6682598A/en not_active Abandoned
- 1998-03-04 CA CA002283474A patent/CA2283474A1/fr not_active Abandoned
- 1998-03-04 EP EP98908909A patent/EP0975792B1/fr not_active Expired - Lifetime
-
2000
- 2000-07-31 HK HK00104775A patent/HK1026234A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA2283474A1 (fr) | 1998-09-11 |
EP0975792A4 (fr) | 2002-12-04 |
ATE375399T1 (de) | 2007-10-15 |
EP0975792A1 (fr) | 2000-02-02 |
AU6682598A (en) | 1998-09-22 |
DE69838544D1 (de) | 2007-11-22 |
DE69838544T2 (de) | 2008-07-24 |
WO1998039469A1 (fr) | 1998-09-11 |
HK1026234A1 (en) | 2000-12-08 |
EP0975792B1 (fr) | 2007-10-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |