IL130200A0 - Phenyl acetamides as spla2 inhibitors - Google Patents
Phenyl acetamides as spla2 inhibitorsInfo
- Publication number
- IL130200A0 IL130200A0 IL13020097A IL13020097A IL130200A0 IL 130200 A0 IL130200 A0 IL 130200A0 IL 13020097 A IL13020097 A IL 13020097A IL 13020097 A IL13020097 A IL 13020097A IL 130200 A0 IL130200 A0 IL 130200A0
- Authority
- IL
- Israel
- Prior art keywords
- spla2 inhibitors
- phenyl acetamides
- acetamides
- phenyl
- spla2
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C07C233/11—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C07C233/04—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C233/05—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3250896P | 1996-12-03 | 1996-12-03 | |
| PCT/US1997/021622 WO1998024756A1 (en) | 1996-12-03 | 1997-11-25 | Phenyl acetamides as spla2 inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL130200A0 true IL130200A0 (en) | 2000-06-01 |
Family
ID=21865299
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13020097A IL130200A0 (en) | 1996-12-03 | 1997-11-25 | Phenyl acetamides as spla2 inhibitors |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6353128B1 (hu) |
| EP (1) | EP0946495B1 (hu) |
| JP (1) | JP2001505575A (hu) |
| KR (1) | KR20000069248A (hu) |
| AU (1) | AU5589298A (hu) |
| BR (1) | BR9713987A (hu) |
| CA (1) | CA2273995A1 (hu) |
| DE (1) | DE69714289T2 (hu) |
| ES (1) | ES2181052T3 (hu) |
| HU (1) | HUP9904172A2 (hu) |
| IL (1) | IL130200A0 (hu) |
| WO (1) | WO1998024756A1 (hu) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6407104B1 (en) | 1998-03-31 | 2002-06-18 | Shionogi & Co., Ltd. | Pyrrolo[1,2-a]pyrazine spla2 inhibitor |
| KR20010034881A (ko) | 1998-05-21 | 2001-04-25 | 시오노 요시히코 | ｓＰＬＡ2 억제 효과를 갖는 피롤로[1,2-ｂ]피리다진 유도체 |
| AU6004799A (en) | 1998-10-14 | 2000-05-01 | Shionogi & Co., Ltd. | Remedies or preventives for ischemic reflow failure |
| FR2793791B1 (fr) * | 1999-05-19 | 2002-01-25 | Univ Paris 7 Denis Diderot | Nouveaux composes inhibiteurs specifiques de phospholipases a2 |
| AU6015600A (en) | 1999-07-19 | 2001-02-05 | Shionogi & Co., Ltd. | Tricyclic compounds having spla2-inhibitory activities |
| AU6023200A (en) | 1999-08-02 | 2001-02-19 | Shionogi & Co., Ltd. | Tricyclic compounds having spla2-inhibitory activities |
| AU6473600A (en) | 1999-08-23 | 2001-03-19 | Shionogi & Co., Ltd. | Pyrrolotriazine derivatives having spla2-inhibitory activities |
| SE0000754D0 (sv) * | 2000-03-07 | 2000-03-07 | Amersham Pharm Biotech Ab | Mass spectral peak identification |
| WO2002000256A1 (en) | 2000-06-29 | 2002-01-03 | Shionogi & Co., Ltd. | Remedies for cirrhosis |
| JPWO2002000621A1 (ja) | 2000-06-29 | 2004-04-22 | 塩野義製薬株式会社 | Ｘ型ｓＰＬＡ２阻害作用を有する化合物 |
| TWI314457B (hu) | 2001-03-19 | 2009-09-11 | Shionogi & Co | |
| NZ624963A (en) | 2009-04-29 | 2016-07-29 | Amarin Pharmaceuticals Ie Ltd | Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same |
| US9963439B2 (en) * | 2013-08-20 | 2018-05-08 | University Of Washington Through Its Center For Commercialization | Specific inhibitors of cytochrome P450 26 retinoic acid hydroxylase |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1584246A (en) | 1976-06-16 | 1981-02-11 | Ici Ltd | Carboxamidoesters |
| US4256758A (en) * | 1979-06-11 | 1981-03-17 | Merck & Co., Inc. | 4-Substituted-3-hydroxy-3-pyrroline-2,5-dione inhibitors of glycolic acid oxidase |
| CA1274843A (en) | 1984-05-18 | 1990-10-02 | Yoshiharu Hayashi | 2-nitro-5-(2'-chloro-4'- trifluoromethylphenoxy)phenylacetic ester, thioester and amide, process for preparation thereof, herbicidal composition, and method for destruction of undesirable weeds |
| DE3812768A1 (de) | 1988-04-16 | 1989-10-26 | Bayer Ag | Halogensubstituierte phenoxybenzylverbindungen |
| CA2240395A1 (en) | 1995-12-13 | 1997-06-19 | David Kent Herron | Naphthyl acetamides as spla2 inhibitors |
-
1997
- 1997-11-24 US US08/976,858 patent/US6353128B1/en not_active Expired - Fee Related
- 1997-11-25 AU AU55892/98A patent/AU5589298A/en not_active Abandoned
- 1997-11-25 CA CA002273995A patent/CA2273995A1/en not_active Abandoned
- 1997-11-25 KR KR1019997004847A patent/KR20000069248A/ko not_active Application Discontinuation
- 1997-11-25 EP EP97952228A patent/EP0946495B1/en not_active Expired - Lifetime
- 1997-11-25 HU HU9904172A patent/HUP9904172A2/hu unknown
- 1997-11-25 DE DE69714289T patent/DE69714289T2/de not_active Expired - Fee Related
- 1997-11-25 WO PCT/US1997/021622 patent/WO1998024756A1/en not_active Application Discontinuation
- 1997-11-25 IL IL13020097A patent/IL130200A0/xx unknown
- 1997-11-25 ES ES97952228T patent/ES2181052T3/es not_active Expired - Lifetime
- 1997-11-25 JP JP52565298A patent/JP2001505575A/ja not_active Withdrawn
- 1997-11-25 BR BR9713987-4A patent/BR9713987A/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US6353128B1 (en) | 2002-03-05 |
| EP0946495A4 (en) | 2000-04-12 |
| DE69714289D1 (en) | 2002-08-29 |
| DE69714289T2 (de) | 2003-01-16 |
| EP0946495A1 (en) | 1999-10-06 |
| HUP9904172A2 (hu) | 2000-05-28 |
| WO1998024756A1 (en) | 1998-06-11 |
| CA2273995A1 (en) | 1998-06-11 |
| ES2181052T3 (es) | 2003-02-16 |
| BR9713987A (pt) | 2000-02-08 |
| EP0946495B1 (en) | 2002-07-24 |
| KR20000069248A (ko) | 2000-11-25 |
| JP2001505575A (ja) | 2001-04-24 |
| AU5589298A (en) | 1998-06-29 |
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