IL128728A0 - Compositions for reducing host vs. graft reaction - Google Patents
Compositions for reducing host vs. graft reactionInfo
- Publication number
- IL128728A0 IL128728A0 IL12872897A IL12872897A IL128728A0 IL 128728 A0 IL128728 A0 IL 128728A0 IL 12872897 A IL12872897 A IL 12872897A IL 12872897 A IL12872897 A IL 12872897A IL 128728 A0 IL128728 A0 IL 128728A0
- Authority
- IL
- Israel
- Prior art keywords
- hsp60
- compositions
- graft reaction
- hvgr
- severity
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 108010058432 Chaperonin 60 Proteins 0.000 abstract 4
- 102000006303 Chaperonin 60 Human genes 0.000 abstract 4
- 230000005784 autoimmunity Effects 0.000 abstract 3
- 230000003828 downregulation Effects 0.000 abstract 2
- 206010052779 Transplant rejections Diseases 0.000 abstract 1
- 230000036039 immunity Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000003614 tolerogenic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
- G01N33/505—Cells of the immune system involving T-cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Urology & Nephrology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Marine Sciences & Fisheries (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Transplantation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/706,209 US5993803A (en) | 1996-08-30 | 1996-08-30 | Method of reducing the severity of host vs graft reaction by down-regulating hsp60 autoimmunity |
| PCT/US1997/015294 WO1998008536A2 (en) | 1996-08-30 | 1997-09-02 | Method of reducing the severity of host vs. graft reaction by down-regulating hsp60 autoimmunity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL128728A0 true IL128728A0 (en) | 2000-01-31 |
Family
ID=24836651
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL12872897A IL128728A0 (en) | 1996-08-30 | 1997-09-02 | Compositions for reducing host vs. graft reaction |
| IL128728A IL128728A (en) | 1996-08-30 | 1999-02-25 | Compositions for reducing host vs. graft reaction |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL128728A IL128728A (en) | 1996-08-30 | 1999-02-25 | Compositions for reducing host vs. graft reaction |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5993803A (xx) |
| EP (1) | EP0921810B1 (xx) |
| JP (1) | JP4256474B2 (xx) |
| AT (1) | ATE237344T1 (xx) |
| AU (1) | AU722576B2 (xx) |
| CA (1) | CA2263816C (xx) |
| DE (1) | DE69721007T2 (xx) |
| DK (1) | DK0921810T3 (xx) |
| ES (1) | ES2198594T3 (xx) |
| IL (2) | IL128728A0 (xx) |
| WO (1) | WO1998008536A2 (xx) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9911772D0 (en) * | 1999-05-21 | 1999-07-21 | Semmelweis University Of Medic | Diagnosis and treatment of atherosclerosis |
| CA2394504A1 (en) * | 1999-12-15 | 2001-06-21 | Peptor Ltd. | Fragments and antagonists of heat shock protein 60 |
| IL150113A0 (en) * | 1999-12-15 | 2002-12-01 | Peptor Ltd | Fragments and antagonists of heat shock protein 60 |
| US6812205B2 (en) * | 2000-03-15 | 2004-11-02 | The Brigham & Women's Hospital, Inc. | Suppression of vascular disorders by mucosal administration of heat shock protein peptides |
| US7608683B2 (en) * | 2000-08-09 | 2009-10-27 | The Regents Of The University Of California | Stress proteins and peptides and methods of use thereof |
| US6989146B2 (en) * | 2000-08-09 | 2006-01-24 | The Regents Of The University Of California | Stress proteins and peptides and methods of use thereof |
| EP1335741A4 (en) * | 2000-08-25 | 2005-10-26 | Yeda Res & Dev | METHOD FOR THE PREVENTION OF AUTOIMMUNE DISEASES WITH CpG-CONTAINING POLYNUCLEOTIDES (04.03.02) |
| JP4264257B2 (ja) | 2000-11-01 | 2009-05-13 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 熱ショックタンパク質に由来する免疫調節ペプチドとその使用 |
| WO2003063759A2 (en) * | 2002-01-31 | 2003-08-07 | Peptor Ltd. | Hsp peptides and analogs for modulation of immune responses via antigen presenting cells |
| WO2003070761A1 (en) * | 2002-02-19 | 2003-08-28 | Yeda Research And Development Co. Ltd. | Dual-effect ligands comprising anti-inflammatory hsp peptide epitopes for immunomodulation |
| ES2433915T3 (es) * | 2002-05-21 | 2013-12-13 | Irun R. Cohen | Vacunas de ADN que codifican proteínas de choque térmico |
| US7494812B2 (en) * | 2003-04-01 | 2009-02-24 | University Of Southern California | Generation of human regulatory T cells by bacterial toxins for the treatment of inflammatory disorders |
| CA2547079A1 (en) * | 2003-11-24 | 2005-06-02 | Yeda Research & Development Co. Ltd. | Dna vaccines encoding hsp60 peptide fragments for treating autoimmune diseases |
| CA2595520A1 (en) | 2004-01-28 | 2005-08-11 | Develogen Israel Ltd. | Hsp therapy in conjunction with a low antigenicity diet |
| CU23504A1 (es) | 2004-09-24 | 2010-04-13 | Ct Ingenieria Genetica Biotech | Péptidos y derivados tipo apl de la hsp60 y composiciones farmacéuticas |
| US8691772B2 (en) | 2005-01-04 | 2014-04-08 | Yeda Research And Development Co. Ltd. | HSP60, HSP60 peptides and T cell vaccines for immunomodulation |
| CN104203263A (zh) | 2012-03-01 | 2014-12-10 | 耶达研究与发展有限公司 | 利用HSP60衍生肽再生胰岛β细胞 |
| WO2013128450A1 (en) | 2012-03-01 | 2013-09-06 | Yeda Research And Development Co. Ltd. | Hsp60 derived peptides and peptide analogs for suppression and treatment of non-autoimmune diabetes |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL92629A0 (en) * | 1989-12-10 | 1990-08-31 | Yeda Res & Dev | Direct binding of t-cell epitopes to mhc gene products on intact living antigen presenting cells and the use thereof for identifying epitopes causing autoimmune diseases and pharmaceutical compositions for treating such diseases |
| EP0503055A1 (en) * | 1990-09-06 | 1992-09-16 | Rijksuniversiteit Utrecht | Inhibitor of lymphocyte response and immune-related disease |
| IL114407A0 (en) * | 1995-06-30 | 1995-10-31 | Yeda Res & Dev | Novel peptides and pharmaceutical compositions comprising them |
| IL114458A0 (en) * | 1995-07-05 | 1995-11-27 | Yeda Res & Dev | Therapeutic preparations for treatment of T cell mediated diseases |
-
1996
- 1996-08-30 US US08/706,209 patent/US5993803A/en not_active Expired - Lifetime
-
1997
- 1997-09-02 IL IL12872897A patent/IL128728A0/xx active IP Right Grant
- 1997-09-02 EP EP97940708A patent/EP0921810B1/en not_active Expired - Lifetime
- 1997-09-02 ES ES97940708T patent/ES2198594T3/es not_active Expired - Lifetime
- 1997-09-02 AT AT97940708T patent/ATE237344T1/de not_active IP Right Cessation
- 1997-09-02 DK DK97940708T patent/DK0921810T3/da active
- 1997-09-02 CA CA002263816A patent/CA2263816C/en not_active Expired - Fee Related
- 1997-09-02 WO PCT/US1997/015294 patent/WO1998008536A2/en active IP Right Grant
- 1997-09-02 JP JP51198498A patent/JP4256474B2/ja not_active Expired - Fee Related
- 1997-09-02 AU AU42426/97A patent/AU722576B2/en not_active Ceased
- 1997-09-02 DE DE69721007T patent/DE69721007T2/de not_active Expired - Lifetime
-
1999
- 1999-02-25 IL IL128728A patent/IL128728A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0921810A2 (en) | 1999-06-16 |
| ES2198594T3 (es) | 2004-02-01 |
| CA2263816A1 (en) | 1998-03-05 |
| ATE237344T1 (de) | 2003-05-15 |
| JP4256474B2 (ja) | 2009-04-22 |
| IL128728A (en) | 2006-09-05 |
| DE69721007T2 (de) | 2004-02-12 |
| AU4242697A (en) | 1998-03-19 |
| AU722576B2 (en) | 2000-08-10 |
| DE69721007D1 (de) | 2003-05-22 |
| CA2263816C (en) | 2008-12-30 |
| WO1998008536A2 (en) | 1998-03-05 |
| EP0921810B1 (en) | 2003-04-16 |
| US5993803A (en) | 1999-11-30 |
| WO1998008536A3 (en) | 1998-05-07 |
| DK0921810T3 (da) | 2003-07-28 |
| JP2001500488A (ja) | 2001-01-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed |