IL127563A0 - Cell adhesion inhibiting compounds - Google Patents

Cell adhesion inhibiting compounds

Info

Publication number
IL127563A0
IL127563A0 IL12756397A IL12756397A IL127563A0 IL 127563 A0 IL127563 A0 IL 127563A0 IL 12756397 A IL12756397 A IL 12756397A IL 12756397 A IL12756397 A IL 12756397A IL 127563 A0 IL127563 A0 IL 127563A0
Authority
IL
Israel
Prior art keywords
cell adhesion
inhibiting compounds
adhesion inhibiting
compounds
cell
Prior art date
Application number
IL12756397A
Other languages
English (en)
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Publication of IL127563A0 publication Critical patent/IL127563A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
IL12756397A 1996-06-21 1997-06-18 Cell adhesion inhibiting compounds IL127563A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9613112.3A GB9613112D0 (en) 1996-06-21 1996-06-21 Chemical compounds
PCT/GB1997/001641 WO1997049731A1 (en) 1996-06-21 1997-06-18 Cell adhesion inhibiting compounds

Publications (1)

Publication Number Publication Date
IL127563A0 true IL127563A0 (en) 1999-10-28

Family

ID=10795723

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12756397A IL127563A0 (en) 1996-06-21 1997-06-18 Cell adhesion inhibiting compounds

Country Status (14)

Country Link
US (1) US6235711B1 (ja)
EP (1) EP0910582A1 (ja)
JP (1) JP2000513350A (ja)
KR (1) KR20000022075A (ja)
AU (1) AU3102797A (ja)
CA (1) CA2254995A1 (ja)
GB (1) GB9613112D0 (ja)
HR (1) HRP970338A2 (ja)
ID (1) ID19445A (ja)
IL (1) IL127563A0 (ja)
NO (1) NO985966D0 (ja)
NZ (1) NZ332778A (ja)
WO (1) WO1997049731A1 (ja)
ZA (1) ZA975436B (ja)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
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GB9820338D0 (en) * 1998-09-19 1998-11-11 Zeneca Ltd Chemical compounds
JP2002526090A (ja) * 1998-09-19 2002-08-20 アストラゼネカ・アクチエボラーグ インテグリンリガンド仲介疾患の診断および処置に適当なヒトのベータ1インテグリンサブユニット遺伝子における多型性
BR0016818A (pt) 1999-12-28 2002-10-01 Pfizer Prod Inc Inibidores não-peptidila de adesão celular dependente de vla-4 úteis no tratamento de doenças inflamatórias, auto-imunes e respiratórias
WO2001051508A1 (en) * 2000-01-14 2001-07-19 Science & Technology Corporation @ Unm Peptide inhibitors of lfa-1/icam-1 interaction
US20040241689A1 (en) * 2001-07-31 2004-12-02 Baseman Joel B. Antigens of and antibodies to translocated molecules of microorganisms and uses thereof
US7700565B2 (en) * 2005-09-23 2010-04-20 Nitto Denko Corporation Peptide nucleic acid based guanidinium compounds
WO2007038172A2 (en) * 2005-09-23 2007-04-05 Nitto Denko Corporation Guanidinium carriers
WO2007038169A2 (en) * 2005-09-23 2007-04-05 Nitto Denko Corporation Multi-valent guanidinium compounds for molecular translocation across cellular membranes and epithelial tissues
AU2008219007A1 (en) 2007-02-20 2008-08-28 Merrimack Pharmaceuticals, Inc. Methods of treating multiple sclerosis by administration of alpha-fetoprotein in combination with an integrin antagonist
EP2045601A1 (en) * 2007-03-26 2009-04-08 Koninklijke Philips Electronics N.V. Use of microcarrier beads for detection and/or isolation of cells by flow cytometry and/or dielectrophoresis
CA2721093A1 (en) 2008-04-11 2009-10-15 Merrimack Pharmaceuticals, Inc. Human serum albumin linkers and conjugates thereof
EP2547693B1 (en) 2010-03-19 2015-03-11 H. Lee Moffitt Cancer Center & Research Institute Integrin interaction inhibitors for the treatment of cancer
EP2769223A1 (en) 2011-10-17 2014-08-27 Westfälische Wilhelms-Universität Münster Assessment of pml risk and methods based thereon
US9273093B2 (en) * 2012-10-11 2016-03-01 Protagonist Therapeutics, Inc. α4β7 peptide dimer antagonists
DK2968443T3 (da) 2013-03-15 2021-12-06 Protagonist Therapeutics Inc Hepcidinanaloger og anvendelser deraf
US20140294901A1 (en) * 2013-04-02 2014-10-02 Protagonist Therapeutics, Inc. Novel a4b7 peptide dimer antagonists
US20140294902A1 (en) * 2013-04-02 2014-10-02 Protagonist Therapeutics, Inc. Novel a4b7 peptide antagonists
WO2015048477A1 (en) 2013-09-27 2015-04-02 H. Lee Moffitt Cancer Center And Research Institute, Inc. Cyclic peptide conjugates and methods of use
GB201400292D0 (en) 2014-01-08 2014-02-26 Haemostatix Ltd Peptide dendrimers and agents
WO2015176035A1 (en) 2014-05-16 2015-11-19 Protagonist Therapeutics, Inc. α4β7 INTEGRIN THIOETHER PEPTIDE ANTAGONISTS
EP3169403B1 (en) 2014-07-17 2024-02-14 Protagonist Therapeutics, Inc. Oral peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory bowel diseases
RU2017114414A (ru) 2014-10-01 2018-11-06 Протагонист Терепьютикс, Инк. НОВЫЕ АНТАГОНИСТЫ α4β7 НА ОСНОВЕ МОНОМЕРНЫХ И ДИМЕРНЫХ ПЕПТИДОВ
EP3201217A4 (en) * 2014-10-01 2018-07-18 Protagonist Therapeutics Inc. Novel cyclic monomer and dimer peptides having integrin antagonist activity
US10787490B2 (en) 2015-07-15 2020-09-29 Protaganist Therapeutics, Inc. Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases
US20190002503A1 (en) 2015-12-30 2019-01-03 Protagonist Therapeutics, Inc. Analogues of hepcidin mimetics with improved in vivo half lives
WO2017165676A1 (en) 2016-03-23 2017-09-28 Protagonist Therapeutics, Inc. METHODS FOR SYNTHESIZING α4β7 PEPTIDE ANTAGONISTS
EP3621980A4 (en) * 2017-05-10 2021-06-30 Zealand Pharma A/S HOMODETIC CYCLIC PEPTIDES TARGETING INTEGRIN ALPHA4 BETA7
US10278957B2 (en) 2017-09-11 2019-05-07 Protagonist Therapeutics, Inc. Opioid agonist peptides and uses thereof
EP3749345A4 (en) 2018-02-08 2022-04-06 Protagonist Therapeutics, Inc. CONJUGATED HEPCIDIN MIMETICS
AU2020311395A1 (en) 2019-07-10 2022-02-03 Protagonist Therapeutics, Inc. Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases
WO2021146441A1 (en) 2020-01-15 2021-07-22 Janssen Biotech, Inc. Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases
TW202237167A (zh) 2020-11-20 2022-10-01 比利時商健生藥品公司 介白素-23受體之肽抑制劑組合物
JP2023117892A (ja) * 2022-02-14 2023-08-24 公益財団法人 鷹揚郷 ヘプシジン結合ペプチド

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZW6189A1 (en) 1988-05-09 1990-05-09 Smithkline Beckman Corp Anti-aggregatory peptides
NZ235563A (en) 1989-10-13 1993-04-28 Merck & Co Inc Fibrinogen receptor antagonist and pharmaceutical composition
US5192746A (en) 1990-07-09 1993-03-09 Tanabe Seiyaku Co., Ltd. Cyclic cell adhesion modulation compounds
US5229366A (en) 1990-10-23 1993-07-20 Fuji Photo Film Co., Ltd. Peptide-containing polyethylene glycol derivatives and application thereof
IL102646A (en) 1992-07-26 1996-05-14 Yeda Res & Dev Non-peptidic surrogates of the ldv sequence and pharmaceutical compositions comprising them
WO1994015958A2 (en) 1993-01-08 1994-07-21 Tanabe Seiyaku Co., Ltd. Peptide inhibitors of cell adhesion
US5981478A (en) 1993-11-24 1999-11-09 La Jolla Cancer Research Foundation Integrin-binding peptides
AU693143B2 (en) 1993-12-06 1998-06-25 Cytel Corporation CS-1 peptidomimetics, compositions and methods of using the same
JPH10502349A (ja) * 1994-06-29 1998-03-03 テキサス・バイオテクノロジー・コーポレイシヨン インテグリンα▲下4▼β▲下1▼のVCAM−1またはフィブロネクチンへの結合を阻害する方法
US5510332A (en) 1994-07-07 1996-04-23 Texas Biotechnology Corporation Process to inhibit binding of the integrin α4 62 1 to VCAM-1 or fibronectin and linear peptides therefor
US5811391A (en) 1994-08-25 1998-09-22 Cytel Corporation Cyclic CS-1 peptidomimetics, compositions and methods of using same
GB9524630D0 (en) * 1994-12-24 1996-01-31 Zeneca Ltd Chemical compounds

Also Published As

Publication number Publication date
HRP970338A2 (en) 1998-04-30
ID19445A (id) 1998-07-09
CA2254995A1 (en) 1997-12-31
US6235711B1 (en) 2001-05-22
JP2000513350A (ja) 2000-10-10
NO985966L (no) 1998-12-18
AU3102797A (en) 1998-01-14
EP0910582A1 (en) 1999-04-28
ZA975436B (en) 1997-12-22
NZ332778A (en) 2000-08-25
WO1997049731A1 (en) 1997-12-31
GB9613112D0 (en) 1996-08-28
KR20000022075A (ko) 2000-04-25
NO985966D0 (no) 1998-12-18

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