IL123569A - Attenuated shigella strain for delivering a mamalian expression plasmid into a mammalian cell - Google Patents
Attenuated shigella strain for delivering a mamalian expression plasmid into a mammalian cellInfo
- Publication number
- IL123569A IL123569A IL123569A IL12356996A IL123569A IL 123569 A IL123569 A IL 123569A IL 123569 A IL123569 A IL 123569A IL 12356996 A IL12356996 A IL 12356996A IL 123569 A IL123569 A IL 123569A
- Authority
- IL
- Israel
- Prior art keywords
- shigella
- cells
- bacteria
- cell
- dna
- Prior art date
Links
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/025—Enterobacteriales, e.g. Enterobacter
- A61K39/0283—Shigella
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Mycology (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US331895P | 1995-09-06 | 1995-09-06 | |
| US08/523,855 US5824538A (en) | 1995-09-06 | 1995-09-06 | Shigella vector for delivering DNA to a mammalian cell |
| US1803596P | 1996-05-21 | 1996-05-21 | |
| PCT/US1996/014190 WO1997008955A1 (en) | 1995-09-06 | 1996-09-06 | Bacterial delivery system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL123569A0 IL123569A0 (en) | 1998-10-30 |
| IL123569A true IL123569A (en) | 2006-10-05 |
Family
ID=27357382
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL123569A IL123569A (en) | 1995-09-06 | 1996-09-06 | Attenuated shigella strain for delivering a mamalian expression plasmid into a mammalian cell |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0881884A4 (de) |
| JP (1) | JP2000500734A (de) |
| AU (1) | AU731061B2 (de) |
| CA (1) | CA2231332C (de) |
| IL (1) | IL123569A (de) |
| WO (1) | WO1997008955A1 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU5756298A (en) | 1997-04-18 | 1998-11-13 | Gesellschaft Fur Biotechnologische Forschung Mbh | Attenuated salmonella strain used as a vehicle for oral immunization |
| US6080849A (en) | 1997-09-10 | 2000-06-27 | Vion Pharmaceuticals, Inc. | Genetically modified tumor-targeted bacteria with reduced virulence |
| WO1999013053A1 (en) | 1997-09-10 | 1999-03-18 | Vion Pharmaceuticals, Inc. | Genetically modified tumor-targeted bacteria with reduced virulence |
| US6368604B1 (en) | 1997-09-26 | 2002-04-09 | University Of Maryland Biotechnology Institute | Non-pyrogenic derivatives of lipid A |
| EP1021548A1 (de) | 1997-10-07 | 2000-07-26 | University Of Maryland Biotechnology Institute | Verfahren zür einführung und expression von rna in tierischen zellen |
| US6825028B1 (en) * | 1998-12-11 | 2004-11-30 | Christoph Von Eichel-Streiber | Recombinant listeria |
| DE19754938B4 (de) * | 1997-12-11 | 2006-04-20 | Christoph von Dr. Eichel-Streiber | TGC-Verfahren zur Induktion einer zielgerichteten, somatischen Transgenität |
| US6143551A (en) * | 1997-12-29 | 2000-11-07 | Schering Aktiengesellschaft | Delivery of polypeptide-encoding plasmid DNA into the cytosol of macrophages by attenuated listeria suicide bacteria |
| CU22661A1 (es) * | 1997-12-30 | 2001-04-27 | Cnic Ct Nac Investigaciones | Nuevos candidatos vacunales de vibrio cholerae y método de obtención |
| US6596477B1 (en) | 1998-09-28 | 2003-07-22 | University Of Maryland Biotechnology Institute | Treatment and prevention of immunodeficiency virus infection by administration of non-pyrogenic derivatives of lipid A |
| JP2004500042A (ja) * | 1999-10-04 | 2004-01-08 | ヴァイオン ファーマシューティカルズ、インコーポレーテッド | エフェクター分子の腫瘍標的送達のための組成物および方法 |
| US6962696B1 (en) | 1999-10-04 | 2005-11-08 | Vion Pharmaceuticals Inc. | Compositions and methods for tumor-targeted delivery of effector molecules |
| KR20070101854A (ko) * | 2004-11-30 | 2007-10-17 | 아에라스 글로벌 티비 백신 파운데이션 | 재조합 이중 가닥 ｒｎａ 뉴클레오캡시드의 생성 및 제조에유용한 세균 패키징 균주 및 그의 용도 |
| DE602005023345D1 (de) * | 2004-12-17 | 2010-10-14 | Beth Israel Hospital | Zusammensetzungen für bakteriell vermitteltes gen-silencing sowie verfahren zur verwendung davon |
| US9597379B1 (en) | 2010-02-09 | 2017-03-21 | David Gordon Bermudes | Protease inhibitor combination with therapeutic proteins including antibodies |
| US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5077044A (en) * | 1980-05-19 | 1991-12-31 | The Board Of Trustees Of The Leland Stanford Jr. University | Novel non-reverting shigella live vaccines |
| US4632830A (en) * | 1981-07-31 | 1986-12-30 | The United States Of America As Represented By The Secretary Of The Army | Oral vaccine for immunization against enteric disease |
| AR242989A1 (es) * | 1988-07-15 | 1993-06-30 | Inst Pasteur I Nat De La Sante | Metodo para modificar una cepa salvaje de una shigella entero-invasora para producir una cepa modificada apta para preparar una vacuna contra la cepa salvaje y cepa de shigella asi modificada. |
-
1996
- 1996-09-06 EP EP96932169A patent/EP0881884A4/de not_active Withdrawn
- 1996-09-06 WO PCT/US1996/014190 patent/WO1997008955A1/en not_active Ceased
- 1996-09-06 AU AU71059/96A patent/AU731061B2/en not_active Ceased
- 1996-09-06 IL IL123569A patent/IL123569A/en not_active IP Right Cessation
- 1996-09-06 JP JP9511361A patent/JP2000500734A/ja not_active Ceased
- 1996-09-06 CA CA002231332A patent/CA2231332C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2231332C (en) | 2007-04-17 |
| AU731061B2 (en) | 2001-03-22 |
| EP0881884A1 (de) | 1998-12-09 |
| IL123569A0 (en) | 1998-10-30 |
| CA2231332A1 (en) | 1997-03-13 |
| WO1997008955A1 (en) | 1997-03-13 |
| EP0881884A4 (de) | 2004-07-14 |
| AU7105996A (en) | 1997-03-27 |
| JP2000500734A (ja) | 2000-01-25 |
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| MM9K | Patent not in force due to non-payment of renewal fees |