IL119483A - 2-(Aminomethyl)-3,4,7,9- tetrahydro- 2H-pyrano-2[3,3-e]indol-8-ones their derivatives and pharmaceutical compositions containing them - Google Patents

2-(Aminomethyl)-3,4,7,9- tetrahydro- 2H-pyrano-2[3,3-e]indol-8-ones their derivatives and pharmaceutical compositions containing them

Info

Publication number
IL119483A
IL119483A IL11948396A IL11948396A IL119483A IL 119483 A IL119483 A IL 119483A IL 11948396 A IL11948396 A IL 11948396A IL 11948396 A IL11948396 A IL 11948396A IL 119483 A IL119483 A IL 119483A
Authority
IL
Israel
Prior art keywords
pyrano
indol
aminomethyl
tetrahydro
ones
Prior art date
Application number
IL11948396A
Other languages
English (en)
Other versions
IL119483A0 (en
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of IL119483A0 publication Critical patent/IL119483A0/xx
Publication of IL119483A publication Critical patent/IL119483A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL11948396A 1995-11-06 1996-10-24 2-(Aminomethyl)-3,4,7,9- tetrahydro- 2H-pyrano-2[3,3-e]indol-8-ones their derivatives and pharmaceutical compositions containing them IL119483A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US730795P 1995-11-06 1995-11-06

Publications (2)

Publication Number Publication Date
IL119483A0 IL119483A0 (en) 1997-01-10
IL119483A true IL119483A (en) 1999-06-20

Family

ID=21725405

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11948396A IL119483A (en) 1995-11-06 1996-10-24 2-(Aminomethyl)-3,4,7,9- tetrahydro- 2H-pyrano-2[3,3-e]indol-8-ones their derivatives and pharmaceutical compositions containing them

Country Status (22)

Country Link
EP (1) EP0771801B1 (de)
JP (1) JPH09169764A (de)
KR (1) KR970027086A (de)
CN (1) CN1083843C (de)
AR (1) AR004523A1 (de)
AT (1) ATE177102T1 (de)
AU (1) AU701636B2 (de)
BR (1) BR9605437B1 (de)
CA (1) CA2189525C (de)
CZ (1) CZ286649B6 (de)
DE (1) DE69601611T2 (de)
DK (1) DK0771801T3 (de)
ES (1) ES2128145T3 (de)
GR (1) GR3030132T3 (de)
HU (1) HUP9603058A3 (de)
IL (1) IL119483A (de)
MX (1) MX9605369A (de)
NO (1) NO964684L (de)
NZ (1) NZ299680A (de)
SK (1) SK281085B6 (de)
TW (1) TW467914B (de)
ZA (1) ZA969191B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT923576E (pt) * 1996-08-27 2003-02-28 Wyeth Corp Derivados de 4-amino-etoxi-indolona como agonistas de dopamina d2
JP2001502327A (ja) * 1996-10-15 2001-02-20 アメリカン・ホーム・プロダクツ・コーポレイション ２，３，８，９―テトラヒドロ―７Ｈ―１，４―ジオキシノ［２，３―ｅ］インドール―８―オンのアザヘテロサイクリルメチル誘導体
CN1138761C (zh) * 1997-02-18 2004-02-18 惠氏公司 4－氨基烷氧基－1,3－二氢苯并咪唑－2－酮衍生物、它们的制备方法以及它们作为多巴胺自身受体（d2）激动剂的用途
US5990144A (en) * 1997-02-18 1999-11-23 American Home Products Corporation 4-aminoalkoxy-1,3-dihydrobenzoimidazol-2-one dopamine autoreceptor agonists
US6541502B1 (en) 2001-07-20 2003-04-01 Wyeth 2-(aminomethyl)-tetrahydro-9-oxa-1,3-diaza-cyclopenta[a]-naphthalenyl derivatives with antipsychotic activity
US6541501B2 (en) * 2001-07-20 2003-04-01 Wyeth 2-(aminomethyl)-tetrahydro-9-oxa-1,3-diaza-cyclopenta[a]-naphthalenyl derivatives with antipsychotic activity
TW200811182A (en) 2006-05-25 2008-03-01 Wyeth Corp Oxindoledioxans, synthesis thereof, and intermediates thereto

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4314944A (en) 1980-08-22 1982-02-09 Smithkline Corporation 4-Aminoalkyl-7-hydroxy-2(3H)-indolones
DE4135474A1 (de) 1991-10-28 1993-04-29 Bayer Ag 2-aminomethyl-chromane
DE4140540A1 (de) 1991-12-09 1993-06-17 Bayer Ag Neue azaheterocyclylmethyl-chromane
EP1123933A1 (de) * 1994-10-14 2001-08-16 MERCK PATENT GmbH ZNS wirksames 2-[5-(4-Fluorphenyl)-3-pyridylmethylaminomethyl]chroman

Also Published As

Publication number Publication date
AR004523A1 (es) 1998-12-16
SK141396A3 (en) 1997-05-07
SK281085B6 (sk) 2000-11-07
ES2128145T3 (es) 1999-05-01
HK1010104A1 (en) 1999-06-11
ZA969191B (en) 1998-04-30
HUP9603058A2 (en) 1997-05-28
CA2189525A1 (en) 1997-05-07
BR9605437B1 (pt) 2009-08-11
GR3030132T3 (en) 1999-07-30
DE69601611D1 (de) 1999-04-08
MX9605369A (es) 1997-05-31
HUP9603058A3 (en) 1998-12-28
HU9603058D0 (en) 1996-12-30
AU7055496A (en) 1997-05-15
KR970027086A (ko) 1997-06-24
CN1151989A (zh) 1997-06-18
EP0771801B1 (de) 1999-03-03
CN1083843C (zh) 2002-05-01
AU701636B2 (en) 1999-02-04
CZ286649B6 (cs) 2000-05-17
CA2189525C (en) 2006-04-25
TW467914B (en) 2001-12-11
EP0771801A1 (de) 1997-05-07
NO964684D0 (no) 1996-11-05
DK0771801T3 (da) 1999-09-27
JPH09169764A (ja) 1997-06-30
NZ299680A (en) 1998-05-27
NO964684L (no) 1997-05-07
CZ324096A3 (en) 1997-12-17
ATE177102T1 (de) 1999-03-15
DE69601611T2 (de) 1999-10-21
BR9605437A (pt) 1998-08-04
IL119483A0 (en) 1997-01-10

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Legal Events

Date Code Title Description
FF Patent granted
FF Patent granted
RH1 Patent not in force