IL118934A - 1,2-dioxetane derivatives and compositions for producing light comprising the same - Google Patents

1,2-dioxetane derivatives and compositions for producing light comprising the same

Info

Publication number
IL118934A
IL118934A IL11893496A IL11893496A IL118934A IL 118934 A IL118934 A IL 118934A IL 11893496 A IL11893496 A IL 11893496A IL 11893496 A IL11893496 A IL 11893496A IL 118934 A IL118934 A IL 118934A
Authority
IL
Israel
Prior art keywords
compositions
dioxetane
same
producing light
water
Prior art date
Application number
IL11893496A
Other languages
English (en)
Other versions
IL118934A0 (en
Original Assignee
Governors Of Wayne State Board
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Governors Of Wayne State Board filed Critical Governors Of Wayne State Board
Publication of IL118934A0 publication Critical patent/IL118934A0/xx
Publication of IL118934A publication Critical patent/IL118934A/xx

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D321/00—Heterocyclic compounds containing rings having two oxygen atoms as the only ring hetero atoms, not provided for by groups C07D317/00 - C07D319/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/12—Esters of phosphoric acids with hydroxyaryl compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/6551—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a four-membered ring
    • C07F9/65512—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a four-membered ring condensed with carbocyclic rings or carbocyclic ring systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Luminescent Compositions (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IL11893496A 1995-07-31 1996-07-24 1,2-dioxetane derivatives and compositions for producing light comprising the same IL118934A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/509,305 US5777135A (en) 1995-07-31 1995-07-31 Di-substituted 1,2-dioxetane compounds having increased water solubility and assay compositions

Publications (2)

Publication Number Publication Date
IL118934A0 IL118934A0 (en) 1996-10-31
IL118934A true IL118934A (en) 2000-01-31

Family

ID=24026100

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11893496A IL118934A (en) 1995-07-31 1996-07-24 1,2-dioxetane derivatives and compositions for producing light comprising the same

Country Status (9)

Country Link
US (2) US5777135A (fr)
EP (1) EP0757052B1 (fr)
JP (1) JP3290592B2 (fr)
AT (1) ATE232876T1 (fr)
AU (1) AU703632B2 (fr)
CA (1) CA2182325C (fr)
DE (1) DE69626247T2 (fr)
ES (1) ES2189844T3 (fr)
IL (1) IL118934A (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5856522A (en) * 1995-05-04 1999-01-05 Tropix, Inc. Method of using synthesis of 1,2-dioxetanes and kits therefore
US5578253A (en) * 1994-11-23 1996-11-26 Lumigen, Inc. Chemiluminescent dialkyl-substituted 1,2-dioxetane compounds, methods of synthesis and use
US5721370A (en) * 1995-07-31 1998-02-24 Lumigen Inc. Water soluble tri-substituted 1,2-dioxetane compounds and assay compositions having increased storage stability
US6245928B1 (en) * 1995-07-31 2001-06-12 Lumigen, Inc. Water soluble tri-substituted 1,2-dioxetane compounds having increased storage stability, synthetic processes and intermediates
US6036892A (en) * 1995-07-31 2000-03-14 Lumigen, Inc. Water soluble tri-substituted 1,2-dioxetane compounds having increased storage stability, synthetic processes and intermediates
DE69622605T2 (de) * 1995-10-17 2003-03-13 Tropix Inc Chemilumineszente 1,2-dioxetane mit verbesserter leistung
US6636489B1 (en) 1997-11-03 2003-10-21 Bell South Wireless Data. L.P. Wireless management system and a method for an automated over-the-air managing process for wireless communication device
US6767716B2 (en) * 2000-06-17 2004-07-27 Brij P. Giri Chemluminescent systems containing unsaturated 1,2-dioxetanes
CA2486964C (fr) * 2002-05-23 2011-08-09 Brij Pal Giri Sels d'ammonium et/ou de phosphonium polymeriques ayant des electrons .pi. additionnes et de poids moleculaires plus eleves en tant qu'activateurs de systemes chimiluminescents
US7416898B2 (en) * 2002-10-04 2008-08-26 Giri Brij P Chemiluminescent 1,2-dioxetanes
CN103951704A (zh) * 2013-12-10 2014-07-30 云南民族大学 一种免疫分析用化学发光物amppd的制备方法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5004565A (en) * 1986-07-17 1991-04-02 The Board Of Governors Of Wayne State University Method and compositions providing enhanced chemiluminescence from 1,2-dioxetanes
US4959182A (en) * 1986-07-17 1990-09-25 Board Of Governors Of Wayne State University Method and compositions providing enhanced chemiluminescence from 1,2-dioxetanes
US5013827A (en) * 1986-07-17 1991-05-07 Board Of Governors Of Wayne State University Enhanced chemiluminescence from 1,2-dioxetanes through energy transfer to tethered fluorescers
US5068339A (en) * 1986-07-17 1991-11-26 Board Of Governors Of Wayne State University Enhanced chemiluminescence from 1,2-dioxetanes through energy transfer to tethered fluorescers
US4978614A (en) * 1988-10-26 1990-12-18 Tropix, Inc. Method of detecting a substance using enzymatically-induced decomposition of dioxetanes
CA1340590C (fr) * 1986-07-24 1999-06-08 John C. Voyta Amelioration de la chimioluminescence
US5220005A (en) * 1986-07-24 1993-06-15 Tropix, Inc. Substituted adamantyl dioxetanes
US5112960A (en) * 1989-07-17 1992-05-12 Bronstein Irena Y Chemiluminescent 3-(substituted adamant-2'-ylidene) 1,2-dioxetanes
DE3788203T2 (de) * 1986-07-24 1994-03-31 Tropix Inc Verfahren zum nachweis einer verbindung unter verwendung des enzymatisch induzierten zerfalls von dioxethanen.
US5582980A (en) * 1989-07-17 1996-12-10 Tropix, Inc. Chemiluminescent 1,2-dioxetanes
JPH0731201B2 (ja) * 1987-12-31 1995-04-10 トロピックス・インコーポレーテッド 化学発光による測定法
US4952707A (en) * 1988-06-30 1990-08-28 Tropix, Inc. Enzymatically-cleavable chemiluminescent fused polycyclic ring-containing 1,2-dioxetanes
US5547836A (en) * 1990-08-30 1996-08-20 Tropix, Inc. Enhancement of chemiluminescent assays
DE473984T1 (de) * 1990-09-07 1992-08-13 The Board Of Governors Of Wayne State University, Detroit, Mich. 1,2-dioxetan-verbindungen als chemilumineszierende markierungen fuer organische und biologische molekuele.
US5399497A (en) * 1992-02-26 1995-03-21 Miles, Inc. Capsule chemistry sample liquid analysis system and method
EP0629195B1 (fr) * 1992-03-05 1999-05-26 Tropix, Inc. Synthese de 1,2-dioxetanes chimioluminescentes, hydrosolubles et stables, et intermediaires de ces composes
US5393469A (en) * 1992-03-20 1995-02-28 Lumigen, Inc. Polymeric phosphonium salts providing enhanced chemiluminescence from 1,2-dioxetanes
US5603868A (en) * 1992-10-30 1997-02-18 Abbott Laboratories Chemiluminescent electron-rich aryl-substituted 1,2-dioxetanes
US5451347A (en) * 1993-06-24 1995-09-19 Lumigen, Inc. Methods and compositions providing enhanced chemiluminescence from chemiluminescent compounds using dicationic surfactants
US5578253A (en) * 1994-11-23 1996-11-26 Lumigen, Inc. Chemiluminescent dialkyl-substituted 1,2-dioxetane compounds, methods of synthesis and use
ATE213497T1 (de) * 1995-06-20 2002-03-15 Lumigen Inc Verfahren zur herstellung von 1,2- dioxetanverbindungen und mit schwefel substituierte 1,2-dioxetane als zwischenverbindungen

Also Published As

Publication number Publication date
AU6081896A (en) 1997-02-06
CA2182325A1 (fr) 1997-02-01
EP0757052B1 (fr) 2003-02-19
DE69626247T2 (de) 2003-12-04
ATE232876T1 (de) 2003-03-15
EP0757052A1 (fr) 1997-02-05
US5777135A (en) 1998-07-07
JP3290592B2 (ja) 2002-06-10
US5804103A (en) 1998-09-08
AU703632B2 (en) 1999-03-25
JPH09249659A (ja) 1997-09-22
ES2189844T3 (es) 2003-07-16
CA2182325C (fr) 2009-04-14
IL118934A0 (en) 1996-10-31
DE69626247D1 (de) 2003-03-27

Similar Documents

Publication Publication Date Title
GR910300015T1 (en) Chemiluminescent 1,2-dioxetane compounds
CA2186618A1 (fr) Nouveaux derives de n-alkylacridanthiocarboxylate d'aryle utiles pour la detection par chimioluminescence
IL118934A (en) 1,2-dioxetane derivatives and compositions for producing light comprising the same
CA2146669A1 (fr) Derives de substitution aryliques de 1,2-dioxetanes, riches en electrons, chimioluminescents
BR9813370A (pt) Aparelho de imagem omnidirecional.
AU3030195A (en) Chemiluminescent reagent and assay using a substituted acetanilide for light generation
ATE238268T1 (de) Wasserlösliche trisubstituierte 1,2- dioxetanverbindungen mit erhöhter lagerstabilität,syntheseverfahren und zwischenverbindungen
DE69221118T2 (de) Zielkomponenten-Assay
AU6081796A (en) Improved capsule chemistry analytical methods employing dioxetane chemiluminescence
ATE19828T1 (de) Verbessertes fluoreszierendes immunotestsystem.
Sasamoto et al. A Chemiluminogenic Substrate for N-Acetyl-β-D-glucosaminidase, o-Aminophthalylhydrazido-N-acetyl-β-D-glucosaminide
KR830009497A (ko) 광 라디 에이터
FR2574184B1 (fr) Composes fluorescents, derives d'(amino-4 disulfonato-3,6) naphtalimide, leur application aux dosages immunologiques en polarisation de fluorescence
EP0617288A3 (fr) Composes chimioluminescents avec longueur d'onde d'émission longue et leur utilisation dans des essais.
AU7708191A (en) Barbiturate assay, tracers, immunogens and antibodies and kit
TW363986B (en) A process for producing polyparahydroxy styrene derivatives
TH19547B (th) สารคาร์แบนิไลต์ต้านประสิตค็อกซิดเดีย
TH19547A (th) สารคาร์แบนิไลต์ต้านประสิตค็อกซิดเดีย
AU640514C (en) 1,2-dioxetane compounds as chemiluminescent lables for organic and biological molecules

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees