IL117840A0 - Polypeptides having a functional domain of interest and methods of identifying and using same - Google Patents
Polypeptides having a functional domain of interest and methods of identifying and using sameInfo
- Publication number
- IL117840A0 IL117840A0 IL11784096A IL11784096A IL117840A0 IL 117840 A0 IL117840 A0 IL 117840A0 IL 11784096 A IL11784096 A IL 11784096A IL 11784096 A IL11784096 A IL 11784096A IL 117840 A0 IL117840 A0 IL 117840A0
- Authority
- IL
- Israel
- Prior art keywords
- polypeptides
- interest
- identifying
- methods
- same
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B30/00—Methods of screening libraries
- C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Virology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US41787295A | 1995-04-07 | 1995-04-07 | |
US08/630,915 US6309820B1 (en) | 1995-04-07 | 1996-04-03 | Polypeptides having a functional domain of interest and methods of identifying and using same |
Publications (1)
Publication Number | Publication Date |
---|---|
IL117840A0 true IL117840A0 (en) | 1997-03-18 |
Family
ID=27023893
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL11784096A IL117840A0 (en) | 1995-04-07 | 1996-04-07 | Polypeptides having a functional domain of interest and methods of identifying and using same |
Country Status (7)
Country | Link |
---|---|
US (3) | US6709821B2 (fr) |
EP (1) | EP0833941B1 (fr) |
JP (1) | JPH11509172A (fr) |
AU (1) | AU711141B2 (fr) |
CA (1) | CA2217641A1 (fr) |
IL (1) | IL117840A0 (fr) |
WO (1) | WO1996031625A1 (fr) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6184205B1 (en) * | 1994-07-22 | 2001-02-06 | University Of North Carolina At Chapel Hill | GRB2 SH3 binding peptides and methods of isolating and using same |
US5605830A (en) * | 1995-05-05 | 1997-02-25 | The Wistar Institute Of Anatomy & Biology | Murine and human c-Myc interacting protein |
US6048702A (en) * | 1995-05-05 | 2000-04-11 | The Wistar Institute Of Anatomy And Biology | Murine and human box-dependent myc-interacting protein (Bin1) and uses therefor |
EP1114864B9 (fr) | 1996-12-13 | 2013-05-08 | Schering Corporation | Antigènes de surface de cellules de mammifères |
WO1999031238A1 (fr) * | 1997-12-12 | 1999-06-24 | Kyowa Hakko Kogyo Co., Ltd. | Nouvelle proteine |
CA2328719A1 (fr) * | 1998-04-15 | 1999-10-21 | Hiroyoshi Hidaka | Procede de detection in vivo d'un gene proteique cible a l'aide de medicament |
DE69934107D1 (de) * | 1998-04-16 | 2007-01-04 | Cedar Sinai Health System | Isolierte sh3 gene, die mit myeloproliferativen erkrankungen und leukämie verbunden sind, und deren verwendungen |
US7070954B1 (en) * | 1998-04-16 | 2006-07-04 | Julie R. Korenberg | Isolated SH3 genes associates with myeloproliferative disorders and leukemia and uses thereof |
WO1999055728A2 (fr) * | 1998-04-27 | 1999-11-04 | Hsc Research And Development Limited Partnership | Genes ese et proteines |
US7118886B1 (en) | 1998-04-27 | 2006-10-10 | Hsc Research And Development Limited Partnership | Ese genes and proteins |
CA2329120C (fr) * | 1998-05-22 | 2011-09-13 | Stuart B. Levy | Domaines helice-coude-helice de la famile mara et leurs methodes d'utilisation |
EP0972832A1 (fr) * | 1998-07-16 | 2000-01-19 | Boehringer Mannheim Gmbh | Nouveau géne avec une expression réduite dans les cellules humaines métastasiques de mélanomes et la protéine codée par celui-ci, methodes de production et l'utilisation de celles-ci |
JP2000125875A (ja) * | 1998-10-19 | 2000-05-09 | Japan Science & Technology Corp | ヒトタンパク質STAM2aおよびSTAM2b、 ならびにこれらの分子をコードするcDNA |
EP1146054A4 (fr) * | 1998-12-03 | 2003-08-06 | Ono Pharmaceutical Co | INHIBITEUR DE LIAISON DE Re1A, PROCEDE DE PRODUCTION CORRESPONDANT ET UTILISATION DUDIT INHIBITEUR DE LIAISON |
US6635311B1 (en) | 1999-01-07 | 2003-10-21 | Northwestern University | Methods utilizing scanning probe microscope tips and products therefor or products thereby |
US6827979B2 (en) | 1999-01-07 | 2004-12-07 | Northwestern University | Methods utilizing scanning probe microscope tips and products therefor or produced thereby |
US7029912B1 (en) | 1999-04-09 | 2006-04-18 | Sugen, Inc. | Tyrosine kinase substrate(Tks) proteins |
EP1175490A2 (fr) * | 1999-04-09 | 2002-01-30 | Sugen, Inc. | PROTEINES DE SUBSTRATS DE TYROSINES KINASES (Tks) |
JP2003500080A (ja) * | 1999-05-26 | 2003-01-07 | リセンチア エルテーデー | 設計された結合能を有するsh3ドメインを製造するための方法および材料 |
CN1399680A (zh) * | 1999-06-18 | 2003-02-26 | 生物治疗股份有限公司 | 上皮细胞生长抑制剂 |
US6939714B2 (en) | 1999-06-18 | 2005-09-06 | Biotherapies, Inc. | Epithelial cell growth inhibitors |
US7146176B2 (en) | 2000-06-13 | 2006-12-05 | Shared Spectrum Company | System and method for reuse of communications spectrum for fixed and mobile applications with efficient method to mitigate interference |
AU2001277986A1 (en) * | 2000-07-25 | 2002-02-05 | Axcell Biosciences Corporation | Identification and isolation of novel polypeptides having pdz domains and methods of using same |
AU2002239740A1 (en) | 2000-10-20 | 2002-06-11 | Chad A. Mirkin | Nanolithography methods and products therefor and produced thereby |
AU2002214286A1 (en) * | 2000-11-15 | 2002-05-27 | Akiko Itai | Method of profiling protein |
US7361310B1 (en) | 2001-11-30 | 2008-04-22 | Northwestern University | Direct write nanolithographic deposition of nucleic acids from nanoscopic tips |
WO2004033480A2 (fr) | 2002-05-21 | 2004-04-22 | Northwestern University | Reseaux peptidiques et proteiques et impression lithographique a ecriture directe de peptides et de proteines |
US8877438B2 (en) * | 2010-07-20 | 2014-11-04 | California Institute Of Technology | Self-assembled polynucleotide structure |
FI126633B (en) * | 2015-07-10 | 2017-03-15 | Next Biomed Therapies Oy | Method of Preparation of a Library comprising Recombinant Derivatives of the SH3 Domain of Nephrocystin (NPHP1) |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5094941A (en) * | 1987-12-31 | 1992-03-10 | Zymogenetics, Inc. | Monoclonal antibodies to PDGF |
US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
EP1892296A1 (fr) | 1988-09-02 | 2008-02-27 | Dyax Corporation | Production et sélection de protéines de liaison diversifiées recombinantes |
US5096815A (en) | 1989-01-06 | 1992-03-17 | Protein Engineering Corporation | Generation and selection of novel dna-binding proteins and polypeptides |
US5198346A (en) | 1989-01-06 | 1993-03-30 | Protein Engineering Corp. | Generation and selection of novel DNA-binding proteins and polypeptides |
US5747334A (en) * | 1990-02-15 | 1998-05-05 | The University Of North Carolina At Chapel Hill | Random peptide library |
US5723286A (en) * | 1990-06-20 | 1998-03-03 | Affymax Technologies N.V. | Peptide library and screening systems |
US5677421A (en) * | 1991-01-18 | 1997-10-14 | New York University | Target proteins for eukaryotic tyrosine kinases |
GB9107434D0 (en) * | 1991-04-09 | 1991-05-22 | Medical Res Council | Peptide-based assay |
US6197925B1 (en) * | 1991-08-22 | 2001-03-06 | Sara Lee Corporation | NF-AT polypeptides and polynucleotides |
CA2054602C (fr) * | 1991-10-31 | 2003-04-22 | Anthony Pawson | Methode de dosage d'une substance influant sur un systeme de regulation d'un ligand phosphoryle-sh2 |
BR9305435A (pt) * | 1992-03-06 | 1994-12-27 | Innogenetics Nv | Processo para determinação de peptídeos correspondendo a epítopos imunologicamente importantes e seu uso em um processo para determinação de anticorpos ou peptídeos biotinilados correspondendo a epítopos imunologicamente importantes, processo para preparação dos mesmos e composições contendo os mesmos |
US5491074A (en) * | 1993-04-01 | 1996-02-13 | Affymax Technologies Nv | Association peptides |
JPH09504522A (ja) * | 1993-10-12 | 1997-05-06 | グリコメド・インコーポレイテッド | 細胞接着インヒビターの同定に有用なグリコ−ペプチドのライブラリー |
WO1995024419A1 (fr) * | 1994-03-11 | 1995-09-14 | Ariad Pharmaceuticals, Inc. | Procedes et materiaux d'identification d'inhibiteurs d'interactions moleculaires induites par les domaines sh3 |
AU2233495A (en) * | 1994-03-31 | 1995-10-23 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. | Treatment or diagnosis of abnormal signal transduction disorders |
US5541109A (en) | 1994-04-19 | 1996-07-30 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Expression cloning of c-src SH3-domain binding proteins |
JP4215274B2 (ja) * | 1994-07-22 | 2009-01-28 | ザ ユニバーシティー オブ ノースカロライナ アット チャペル ヒル | Src SH3結合性ペプチドとその分離法と利用法 |
GB9509844D0 (en) * | 1995-05-16 | 1995-07-12 | Cancer Res Campaign Tech | Screening for inhibitors of TCR-MHC interactions |
US6011137A (en) * | 1996-04-03 | 2000-01-04 | University Of North Carolina At Chapel Hill | Identification and isolation of novel polypeptides having WW domains and methods of using same |
EP2311855A3 (fr) * | 2000-10-06 | 2011-05-11 | Novozymes Inc. | Bacillus licheniformis YvnA souche négative |
-
1996
- 1996-04-04 WO PCT/US1996/004454 patent/WO1996031625A1/fr active Application Filing
- 1996-04-04 EP EP96910696A patent/EP0833941B1/fr not_active Expired - Lifetime
- 1996-04-04 AU AU53821/96A patent/AU711141B2/en not_active Ceased
- 1996-04-04 JP JP8530406A patent/JPH11509172A/ja active Pending
- 1996-04-04 CA CA002217641A patent/CA2217641A1/fr not_active Abandoned
- 1996-04-07 IL IL11784096A patent/IL117840A0/xx unknown
-
2001
- 2001-06-13 US US09/879,957 patent/US6709821B2/en not_active Expired - Fee Related
-
2004
- 2004-03-23 US US10/807,856 patent/US7223547B2/en not_active Expired - Fee Related
-
2007
- 2007-05-21 US US11/802,166 patent/US20090264303A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US7223547B2 (en) | 2007-05-29 |
JPH11509172A (ja) | 1999-08-17 |
US20090264303A1 (en) | 2009-10-22 |
US20040157216A1 (en) | 2004-08-12 |
AU5382196A (en) | 1996-10-23 |
US6709821B2 (en) | 2004-03-23 |
WO1996031625A1 (fr) | 1996-10-10 |
EP0833941B1 (fr) | 2008-10-22 |
EP0833941A4 (fr) | 2004-12-08 |
US20020034755A1 (en) | 2002-03-21 |
CA2217641A1 (fr) | 1996-10-10 |
AU711141B2 (en) | 1999-10-07 |
EP0833941A1 (fr) | 1998-04-08 |
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