IL116477A - Bone graft substitute and process for producing same - Google Patents

Bone graft substitute and process for producing same

Info

Publication number
IL116477A
IL116477A IL11647795A IL11647795A IL116477A IL 116477 A IL116477 A IL 116477A IL 11647795 A IL11647795 A IL 11647795A IL 11647795 A IL11647795 A IL 11647795A IL 116477 A IL116477 A IL 116477A
Authority
IL
Israel
Prior art keywords
bone graft
graft substitute
producing same
tcp
mixture
Prior art date
Application number
IL11647795A
Other languages
English (en)
Other versions
IL116477A0 (en
Original Assignee
Hadasit Med Res Service
Yissum Res Dev Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hadasit Med Res Service, Yissum Res Dev Co filed Critical Hadasit Med Res Service
Priority to IL11647795A priority Critical patent/IL116477A/xx
Publication of IL116477A0 publication Critical patent/IL116477A0/xx
Priority to EP96940709A priority patent/EP0868409B1/de
Priority to DE69615859T priority patent/DE69615859T2/de
Priority to CA002237893A priority patent/CA2237893A1/en
Priority to AT96940709T priority patent/ATE206696T1/de
Priority to US09/091,029 priority patent/US6231607B1/en
Priority to AU10708/97A priority patent/AU718966B2/en
Priority to PCT/IL1996/000182 priority patent/WO1997023428A1/en
Publication of IL116477A publication Critical patent/IL116477A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02Inorganic materials
    • A61L27/12Phosphorus-containing materials, e.g. apatite
    • CCHEMISTRY; METALLURGY
    • C04CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04BLIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B35/00Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
    • C04B35/01Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxide ceramics
    • C04B35/447Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxide ceramics based on phosphates, e.g. hydroxyapatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/3094Designing or manufacturing processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • A61F2002/2835Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00179Ceramics or ceramic-like structures
    • A61F2310/00293Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/02Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Ceramic Engineering (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Structural Engineering (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Manufacturing & Machinery (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Materials Engineering (AREA)
  • Vascular Medicine (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Medicinal Preparation (AREA)
IL11647795A 1995-12-21 1995-12-21 Bone graft substitute and process for producing same IL116477A (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IL11647795A IL116477A (en) 1995-12-21 1995-12-21 Bone graft substitute and process for producing same
EP96940709A EP0868409B1 (de) 1995-12-21 1996-12-19 Ersatz für knochentransplantat und seine herstellung
DE69615859T DE69615859T2 (de) 1995-12-21 1996-12-19 Ersatz für knochentransplantat und seine herstellung
CA002237893A CA2237893A1 (en) 1995-12-21 1996-12-19 Bone graft substitute and its preparation
AT96940709T ATE206696T1 (de) 1995-12-21 1996-12-19 Ersatz für knochentransplantat und seine herstellung
US09/091,029 US6231607B1 (en) 1995-12-21 1996-12-19 Bone graft substitute and its preparation
AU10708/97A AU718966B2 (en) 1995-12-21 1996-12-19 Bone graft substitute and its preparation
PCT/IL1996/000182 WO1997023428A1 (en) 1995-12-21 1996-12-19 Bone graft substitute and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL11647795A IL116477A (en) 1995-12-21 1995-12-21 Bone graft substitute and process for producing same

Publications (2)

Publication Number Publication Date
IL116477A0 IL116477A0 (en) 1996-03-31
IL116477A true IL116477A (en) 2000-02-29

Family

ID=11068341

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11647795A IL116477A (en) 1995-12-21 1995-12-21 Bone graft substitute and process for producing same

Country Status (8)

Country Link
US (1) US6231607B1 (de)
EP (1) EP0868409B1 (de)
AT (1) ATE206696T1 (de)
AU (1) AU718966B2 (de)
CA (1) CA2237893A1 (de)
DE (1) DE69615859T2 (de)
IL (1) IL116477A (de)
WO (1) WO1997023428A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003055418A1 (en) * 2001-12-21 2003-07-10 Lagow Richard J Calcium phosphate bone replacement materials and methods of use thereof
IL149562A0 (en) 2002-05-09 2002-11-10 Prochon Ltd Fgf variants and methods for use thereof
IL153699A (en) 2002-12-26 2008-11-26 Prochon Biotech Ltd The composition for transplantation basically
JP3927487B2 (ja) * 2002-12-02 2007-06-06 株式会社大野興業 人工骨モデルの製造方法
US20050010305A1 (en) * 2003-01-28 2005-01-13 Lee Francis Y. Novel bone graft composite
US7067123B2 (en) 2003-04-29 2006-06-27 Musculoskeletal Transplant Foundation Glue for cartilage repair
US7901457B2 (en) 2003-05-16 2011-03-08 Musculoskeletal Transplant Foundation Cartilage allograft plug
WO2005120488A1 (en) * 2004-06-10 2005-12-22 Sara Sarig Aspartic acid for the regeneration of bone matter
US20090319045A1 (en) 2004-10-12 2009-12-24 Truncale Katherine G Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles
US7837740B2 (en) 2007-01-24 2010-11-23 Musculoskeletal Transplant Foundation Two piece cancellous construct for cartilage repair
US20060198863A1 (en) * 2005-03-03 2006-09-07 Musculoskeletal Transplant Foundation Ceramic composition for filling bone defects
US7815926B2 (en) 2005-07-11 2010-10-19 Musculoskeletal Transplant Foundation Implant for articular cartilage repair
WO2007035778A2 (en) 2005-09-19 2007-03-29 Histogenics Corporation Cell-support matrix and a method for preparation thereof
US20080114468A1 (en) * 2006-11-10 2008-05-15 Biomet Manufacturing Corp. Processes for making ceramic medical devices
US8435551B2 (en) 2007-03-06 2013-05-07 Musculoskeletal Transplant Foundation Cancellous construct with support ring for repair of osteochondral defects
US20090054984A1 (en) 2007-08-20 2009-02-26 Histogenics Corporation Method For Use Of A Double-Structured Tissue Implant For Treatment Of Tissue Defects
US8685107B2 (en) 2007-07-03 2014-04-01 Histogenics Corporation Double-structured tissue implant and a method for preparation and use thereof
SE531779C2 (sv) 2007-11-26 2009-08-04 Promimic Ab Framställning av kalciumfosfatpartiklar i nanostorlek som pulver eller beläggning via bifunktionella prekursorer
US20160059044A1 (en) 2009-10-12 2016-03-03 Kona Medical, Inc. Energy delivery to intraparenchymal regions of the kidney to treat hypertension
CN107296977B (zh) * 2012-01-31 2021-03-23 托莱多大学 可注射的、生物可降解的骨接合剂及其制造和使用方法
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI80605C (fi) * 1986-11-03 1990-07-10 Biocon Oy Benkirurgisk biokompositmaterial.
US4861733A (en) 1987-02-13 1989-08-29 Interpore International Calcium phosphate bone substitute materials
DD285240A7 (de) 1988-09-27 1990-12-12 Technisches Glas Veb K Verfahren zur herstellung eines osteoinduktiven knochenersatzmaterials
JP2621622B2 (ja) * 1990-09-27 1997-06-18 三菱マテリアル株式会社 水硬性リン酸カルシウムセメント
CA2143733A1 (en) 1994-03-02 1995-09-03 Yoshikazu Umezu Alpha-tricalcium phosphate ceramic and production method thereof
US5569442A (en) * 1994-11-04 1996-10-29 Norian Corporation Reactive tricalcium phosphate compositions and uses
AU3795395A (en) * 1994-11-30 1996-06-06 Ethicon Inc. Hard tissue bone cements and substitutes

Also Published As

Publication number Publication date
EP0868409A1 (de) 1998-10-07
EP0868409B1 (de) 2001-10-10
DE69615859D1 (de) 2001-11-15
US6231607B1 (en) 2001-05-15
AU718966B2 (en) 2000-05-04
DE69615859T2 (de) 2002-04-11
AU1070897A (en) 1997-07-17
ATE206696T1 (de) 2001-10-15
CA2237893A1 (en) 1997-07-03
WO1997023428A1 (en) 1997-07-03
EP0868409A4 (de) 1998-12-02
IL116477A0 (en) 1996-03-31

Similar Documents

Publication Publication Date Title
IL116477A0 (en) Bone graft substitute and process for producing same
BILTZ et al. The nature of bone carbonate.
US4938938A (en) Process for the preparation of a hydroxyl apatite material
DE3750849T2 (de) Feste kalziumphosphat-materialien.
BR9307825A (pt) Composição contendo fosfato de cálcio processo aperfeiçoado para a preparação da mesma e de um cimento de fosfato de cálcio fosfato tetracálcico conjunto de materiais precursores de composição contendo fosfato de cálcio e polpa
ATE228481T1 (de) Verfahren zur herstellung eines hydroxyapatit enthaltendes biomaterials, hergestelltes biomaterial und chirurgische oder zahnärtzlische anwendung
AU762430C (en) Calcium carbonate synthesis method and resulting product
EP0945147A3 (de) Verfahren zur Herstellung von mineralisierten Kollagenfibrillen und deren Verwendung als Knochenersatzwerkstoff
AU4674697A (en) Method of preparing a poorly crystalline calcium phosphate and methods of its use
EP0945146A3 (de) Verfahren zur Herstellung von mineralisierten Kollagenfibrillen und deren Verwendung als Knochenersatzwerkstoff
EP1642600A4 (de) Medizinisches knochenprothesematerial und verfahren zu seiner herstellung
Okazaki Crystallographic properties of heterogeneous Mg-containing fluoridated apatites synthesized with a two-step supply system
MXPA03005306A (es) Procedimiento para la inerciacion de una ceniza, puzolana artificial obtenida por medio de dicho procedimiento.
Rohanizadeh et al. Ultrastructural study of apatite precipitation in implanted calcium phosphate ceramic: influence of the implantation site
EP1404787A4 (de) Verfahren zur herstellung eines multifunktionalen additivs und verwendung davon
AU635673B2 (en) Implantable biodegradable material and method for producing same
CA2390099A1 (en) Vital tissue for tendon or ligament and process for producing the same
SU814346A1 (ru) Способ лечени вывиха бедра
Arsenjev et al. Calcium hydroxylapatite synthesis
WO2003057137A3 (en) Synthesis of calcium phosphates by mechano-chemical process
Detsch Bone Growing Method and Composition
Okazaki et al. BIOCOMPATIBILITY OF CO3APATITE PREPARATIONS WITH SOLUBILITY GRADIENTS
JPS54116400A (en) Production of apatite hydroxide containing carbonic acid
Ohgushi et al. BIOCOMPATIBILITY OF COAAPATITE PREPARATIONS WITH
Heide et al. Method for Making an Implantable Bone Prosthesis Based on Hydroxyapatite

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees