IL115199A - Composition comprising a polynucleic acid molecule in a liposome and method using said composition - Google Patents

Composition comprising a polynucleic acid molecule in a liposome and method using said composition

Info

Publication number
IL115199A
IL115199A IL11519995A IL11519995A IL115199A IL 115199 A IL115199 A IL 115199A IL 11519995 A IL11519995 A IL 11519995A IL 11519995 A IL11519995 A IL 11519995A IL 115199 A IL115199 A IL 115199A
Authority
IL
Israel
Prior art keywords
composition
liposome
polynucleic acid
acid molecule
vitro
Prior art date
Application number
IL11519995A
Other languages
English (en)
Other versions
IL115199A0 (en
Original Assignee
Opperbas Holding Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Opperbas Holding Bv filed Critical Opperbas Holding Bv
Priority to IL11519995A priority Critical patent/IL115199A/xx
Publication of IL115199A0 publication Critical patent/IL115199A0/xx
Priority to DE69621953T priority patent/DE69621953T2/de
Priority to CA002231172A priority patent/CA2231172A1/en
Priority to PCT/IL1996/000101 priority patent/WO1997010851A2/en
Priority to US09/029,376 priority patent/US6207456B1/en
Priority to JP9512542A priority patent/JPH11514349A/ja
Priority to EP96929504A priority patent/EP0879062B1/en
Priority to AT96929504T priority patent/ATE219380T1/de
Priority to AU68884/96A priority patent/AU703271C/en
Publication of IL115199A publication Critical patent/IL115199A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IL11519995A 1995-09-07 1995-09-07 Composition comprising a polynucleic acid molecule in a liposome and method using said composition IL115199A (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
IL11519995A IL115199A (en) 1995-09-07 1995-09-07 Composition comprising a polynucleic acid molecule in a liposome and method using said composition
DE69621953T DE69621953T2 (de) 1995-09-07 1996-09-05 Vehikel zum einbringen von nukleinsäuren in zellen
CA002231172A CA2231172A1 (en) 1995-09-07 1996-09-05 Nucleic acid delivery vehicle
PCT/IL1996/000101 WO1997010851A2 (en) 1995-09-07 1996-09-05 Nucleic acid delivery vehicle
US09/029,376 US6207456B1 (en) 1995-09-07 1996-09-05 Nucleic acid delivery vehicle
JP9512542A JPH11514349A (ja) 1995-09-07 1996-09-05 核酸デリバリー担体
EP96929504A EP0879062B1 (en) 1995-09-07 1996-09-05 Nucleic acid delivery vehicle
AT96929504T ATE219380T1 (de) 1995-09-07 1996-09-05 Vehikel zum einbringen von nukleinsäuren in zellen
AU68884/96A AU703271C (en) 1995-09-07 1996-09-05 Nucleic acid delivery vehicle

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL11519995A IL115199A (en) 1995-09-07 1995-09-07 Composition comprising a polynucleic acid molecule in a liposome and method using said composition

Publications (2)

Publication Number Publication Date
IL115199A0 IL115199A0 (en) 1995-12-31
IL115199A true IL115199A (en) 2005-05-17

Family

ID=11067956

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11519995A IL115199A (en) 1995-09-07 1995-09-07 Composition comprising a polynucleic acid molecule in a liposome and method using said composition

Country Status (8)

Country Link
US (1) US6207456B1 (xx)
EP (1) EP0879062B1 (xx)
JP (1) JPH11514349A (xx)
AT (1) ATE219380T1 (xx)
CA (1) CA2231172A1 (xx)
DE (1) DE69621953T2 (xx)
IL (1) IL115199A (xx)
WO (1) WO1997010851A2 (xx)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6890555B1 (en) * 1992-02-05 2005-05-10 Qlt, Inc. Liposome compositions of porphyrin photosensitizers
DE19605548A1 (de) * 1996-02-15 1997-09-04 Boehringer Ingelheim Int Zusammensetzung für die Transfektion höherer eukaryotischer Zellen
FR2751222B1 (fr) 1996-07-16 1998-10-09 Capsulis Compositions contenant au moins un acide nucleique et leurs applications dans le domaine biomedical, en particulier en therapie genique
DE19740092A1 (de) * 1997-09-12 1999-03-18 Ulrich Dr Med Hengge Liposomen und Verfahren zur Transfektion von Zellen
WO1999042091A2 (en) 1998-02-19 1999-08-26 Massachusetts Institute Of Technology Use of polycations as endosomolytic agents
US7276359B1 (en) * 1998-03-13 2007-10-02 Wyeth Polynucleotide composition, method of preparation, and use thereof
IL126681A0 (en) * 1998-10-21 1999-08-17 Opperbas Holding Bv Treatment of trauma-related conditions
ATE359764T1 (de) * 2001-02-22 2007-05-15 Opperbas Holding Bv Durch liposome vermittelte dna verabreichung
RU2425053C2 (ru) 2001-07-13 2011-07-27 СиЭмЭс ПЕПТАЙДЗ ПЭЙТЕНТ ХОЛДИНГ КОМПАНИ ЛИМИТЕД Выделенный пептид, стимулирующий противоопухолевый иммунный ответ, фармацевтическая композиция на его основе, способ лечения млекопитающего и способ модуляции иммунного ответа
CN1210297C (zh) * 2001-07-13 2005-07-13 一泰医药研究（深圳）有限公司 序列号17的生物活性肽
EP1551980A4 (en) * 2002-10-09 2006-05-17 Pfizer Prod Inc STABILIZED NAKED DNA COMPOSITIONS
CA2522380A1 (en) * 2003-03-19 2004-09-30 Isogenis, Inc. Specific inhibition of allorejection
TWI353252B (en) 2004-04-28 2011-12-01 Cms Peptides Patent Holding Company Ltd Biologically active peptide vapeehptllteaplnpk der
US20090053249A1 (en) * 2004-07-20 2009-02-26 Yan Qi Specific Inhibition of Autoimmunity and Diseases Associated With Autoantigens
NZ591825A (en) 2005-07-26 2012-10-26 Cms Peptides Patent Holding Company Ltd Biologically active peptides comprising PTTKTYFPHF and their uses in the manufacture of a medicament for modulating fatigue
US20100272769A1 (en) * 2005-08-03 2010-10-28 Amcol International Virus-, Bacteria-, and Fungi-Interacting Layered Phyllosilicates and Methods of Use
US20070031512A1 (en) * 2005-08-03 2007-02-08 Amcol International Corporation Virus-interacting layered phyllosilicates and methods of inactivating viruses
US20080184618A1 (en) * 2005-08-03 2008-08-07 Amcol International Virus-Interacting Layered Phyllosilicates and Methods of Use
CA2628300C (en) 2005-11-02 2018-04-17 Protiva Biotherapeutics, Inc. Modified sirna molecules and uses thereof
US8158152B2 (en) * 2005-11-18 2012-04-17 Scidose Llc Lyophilization process and products obtained thereby
CA2660804A1 (en) * 2006-08-31 2008-03-06 Astellas Pharma Inc. Reverse targeting lipid vesicle
ES2400162T3 (es) * 2006-10-06 2013-04-08 Scil Technology Gmbh Formación de vesículas reconstituidas y secadas para un uso farmacéutico
US8481084B2 (en) * 2007-05-23 2013-07-09 Amcol International Corporation Cholesterol-interacting layered phyllosilicates and methods of reducing hypercholesteremia in a mammal
US9006191B2 (en) 2007-12-27 2015-04-14 Protiva Biotherapeutics, Inc. Silencing of polo-like kinase expression using interfering RNA
AU2009236219B8 (en) 2008-04-15 2015-06-25 Arbutus Biopharma Corporation Silencing of CSN5 gene expression using interfering RNA
US8871515B2 (en) * 2008-09-17 2014-10-28 Isogenis, Inc. Construction of fully-deleted adenovirus-based gene delivery vectors and uses thereof
EP2582387A2 (en) 2010-06-17 2013-04-24 The United States Of America As Represented By The Secretary, National Institutes Of Health Compositions and methods for treating inflammatory conditions
ES2528472T3 (es) 2011-02-03 2015-02-10 The Government Of The U.S.A, As Represented By The Secretary, Dept. Of Health And Human Services Vacunas multivalentes para el virus de la rabia y filovirus
WO2013075132A1 (en) 2011-11-17 2013-05-23 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Therapeutic rna switches compositions and methods of use
US9035039B2 (en) 2011-12-22 2015-05-19 Protiva Biotherapeutics, Inc. Compositions and methods for silencing SMAD4
WO2014046983A1 (en) 2012-09-21 2014-03-27 Intensity Therapeutic Method of treating cancer
US10415037B2 (en) 2014-10-02 2019-09-17 Arbutus Biopharma Corporation Compositions and methods for silencing hepatitis B virus gene expression
US10627340B2 (en) 2015-04-09 2020-04-21 Bikanta Corporation Imaging systems and methods using fluorescent nanodiamonds
US20180245074A1 (en) 2015-06-04 2018-08-30 Protiva Biotherapeutics, Inc. Treating hepatitis b virus infection using crispr
WO2017019891A2 (en) 2015-07-29 2017-02-02 Protiva Biotherapeutics, Inc. Compositions and methods for silencing hepatitis b virus gene expression
CN109069520A (zh) 2016-02-25 2018-12-21 应用生物实验室公司 保护空气传播的病原体和刺激物的组合物和方法
US20170360815A1 (en) 2016-02-25 2017-12-21 Applied Biological Laboratories, Inc. Compositions and methods for protecting against airborne pathogens and irritants
EP4104854A3 (en) 2016-04-04 2023-03-08 The United States of America as represented by the Secretary of the Department of Health and Human Services Multivalent vaccines for rabies virus and coronaviruses

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5283122A (en) 1984-04-19 1994-02-01 University Of Tennessee Research Corporation Fused liposome and acid induced method for liposome fusion
US4789633A (en) * 1984-04-19 1988-12-06 University Of Tennessee Research Corporation Fused liposome and acid induced method for liposome fusion
CA2044593C (en) 1989-11-03 2004-04-20 Kenneth L. Brigham Method of in vivo delivery of functioning foreign genes
NZ244306A (en) * 1991-09-30 1995-07-26 Boehringer Ingelheim Int Composition for introducing nucleic acid complexes into eucaryotic cells, complex containing nucleic acid and endosomolytic agent, peptide with endosomolytic domain and nucleic acid binding domain and preparation
US5928944A (en) 1994-02-04 1999-07-27 The United States Of America As Represented By The Department Of Health And Human Services Method of adenoviral-medicated cell transfection

Also Published As

Publication number Publication date
AU6888496A (en) 1997-04-09
IL115199A0 (en) 1995-12-31
EP0879062A2 (en) 1998-11-25
JPH11514349A (ja) 1999-12-07
WO1997010851A2 (en) 1997-03-27
EP0879062B1 (en) 2002-06-19
ATE219380T1 (de) 2002-07-15
DE69621953T2 (de) 2003-01-30
US6207456B1 (en) 2001-03-27
DE69621953D1 (de) 2002-07-25
CA2231172A1 (en) 1997-03-27
AU703271B2 (en) 1999-03-25
WO1997010851A3 (en) 1997-06-05

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Legal Events

Date Code Title Description
MM9K Patent not in force due to non-payment of renewal fees