IL113357A - Process for preparing alpha,alpha-difluoro-beta-silyloxy-1,3-dioxolane-4-propanoic acid O, S-esters - Google Patents
Process for preparing alpha,alpha-difluoro-beta-silyloxy-1,3-dioxolane-4-propanoic acid O, S-estersInfo
- Publication number
- IL113357A IL113357A IL11335795A IL11335795A IL113357A IL 113357 A IL113357 A IL 113357A IL 11335795 A IL11335795 A IL 11335795A IL 11335795 A IL11335795 A IL 11335795A IL 113357 A IL113357 A IL 113357A
- Authority
- IL
- Israel
- Prior art keywords
- alpha
- silyloxy
- dioxolane
- difluoro
- beta
- Prior art date
Links
- YLDGTYXTMNSOOA-UHFFFAOYSA-N 3-(1,3-dioxolan-4-yl)-2,2-difluoro-3-silyloxypropanoic acid Chemical compound OC(=O)C(F)(F)C(O[SiH3])C1COCO1 YLDGTYXTMNSOOA-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
- C07F7/1872—Preparation; Treatments not provided for in C07F7/20
- C07F7/188—Preparation; Treatments not provided for in C07F7/20 by reactions involving the formation of Si-O linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
- C07F7/1872—Preparation; Treatments not provided for in C07F7/20
- C07F7/1892—Preparation; Treatments not provided for in C07F7/20 by reactions not provided for in C07F7/1876 - C07F7/1888
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL12983095A IL129830A (en) | 1994-04-14 | 1995-04-13 | 2,2-difluoroketene silyl o,s-acetal derivatives and a process for their preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/227,820 US5428176A (en) | 1994-04-14 | 1994-04-14 | Process for preparing 2,2-difluoroketene silyl O,S-acetals and α,α-difluoro-β-silyloxy-1,3-dioxolane-4-propanoic acid O,S-esters |
Publications (2)
Publication Number | Publication Date |
---|---|
IL113357A0 IL113357A0 (en) | 1995-07-31 |
IL113357A true IL113357A (en) | 2000-10-31 |
Family
ID=22854602
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL11335795A IL113357A (en) | 1994-04-14 | 1995-04-13 | Process for preparing alpha,alpha-difluoro-beta-silyloxy-1,3-dioxolane-4-propanoic acid O, S-esters |
Country Status (11)
Country | Link |
---|---|
US (1) | US5428176A (hu) |
EP (3) | EP1258486A3 (hu) |
JP (1) | JPH07285973A (hu) |
KR (1) | KR950032237A (hu) |
BR (1) | BR9501546A (hu) |
CA (1) | CA2146942A1 (hu) |
ES (1) | ES2166800T3 (hu) |
FI (1) | FI951759A (hu) |
HU (1) | HU218118B (hu) |
IL (1) | IL113357A (hu) |
TW (1) | TW317567B (hu) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR0148439B1 (ko) * | 1994-03-11 | 1998-11-02 | 마사까쓰 마쓰모또 | 1,2-디옥세탄 유도체 |
US5756775A (en) * | 1995-12-13 | 1998-05-26 | Eli Lilly And Company | Process to make α,α-difluoro-β-hydroxyl thiol esters |
AU1289697A (en) | 1995-12-13 | 1997-07-03 | Eli Lilly And Company | Alpha, alpha-difluoro-beta-hydroxy thiol esters and their synthesis |
US6001994A (en) * | 1995-12-13 | 1999-12-14 | Eli Lilly And Company | Process for making gemcitabine hydrochloride |
USPP12237P2 (en) | 1999-06-01 | 2001-11-27 | Florfis Ag | Geranium plant named ‘Fisrocky Dark Red’ |
US6284911B1 (en) | 1999-06-29 | 2001-09-04 | Wright Chemical Corporation | Synthesis of vinyl carbonates for use in producing vinyl carbamates |
DE10335061B4 (de) * | 2003-07-31 | 2005-11-17 | Wacker-Chemie Gmbh | Verfahren zur Herstellung von OH-geschützten [4-(2,6-damino-9H-purin-9-yl)-1,3-dioxolan-2-yl]methanol-Derivaten |
KR100578616B1 (ko) * | 2004-07-23 | 2006-05-10 | 한미약품 주식회사 | D-에리트로-2,2-다이플루오로-2-데옥시-1-옥소라이보스화합물의 제조방법 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4417034A (en) * | 1981-06-30 | 1983-11-22 | E. I. Du Pont De Nemours & Co. | Living polymers and process for their preparation |
US4508880A (en) * | 1981-06-30 | 1985-04-02 | E. I. Du Pont De Nemours And Company | "Living" polymers and process for their preparation |
US4414372A (en) * | 1982-06-17 | 1983-11-08 | E. I. Du Pont De Nemours & Co. | Process for preparing living polymers |
US4526988A (en) * | 1983-03-10 | 1985-07-02 | Eli Lilly And Company | Difluoro antivirals and intermediate therefor |
US4482729A (en) * | 1984-03-04 | 1984-11-13 | Daikin Kogyo Co., Ltd. | Fluoroalkyl silyl ketene acetals and a process for preparing the same |
US4780554A (en) * | 1984-11-20 | 1988-10-25 | Union Carbide Corporation | O-silylated ketene acetals and enol ethers and method of preparation |
US4754046A (en) * | 1987-06-25 | 1988-06-28 | Dow Corning Corporation | Stabilized silyl ketene acetals |
US4824981A (en) * | 1987-07-06 | 1989-04-25 | Dow Corning Corporation | Process to produce silyl ketene acetals |
US4746750A (en) * | 1987-08-31 | 1988-05-24 | Dow Corning Corporation | Synthesis of silyl ketene acetal from allyl 2-organoacrylates |
JPH0267250A (ja) * | 1988-09-02 | 1990-03-07 | Asahi Glass Co Ltd | 2,2‐ジフルオロ‐3‐ヒドロキシカルボン酸誘導体の製造法 |
US4824980A (en) * | 1988-09-02 | 1989-04-25 | Dow Corning Corporation | Process to produce O-silyl O,N-ketene acetals |
US5041587A (en) * | 1989-02-14 | 1991-08-20 | Mitsui Toatsu Chemicals, Inc. | Process for preparing organic silicon compound |
JPH02270841A (ja) * | 1989-04-12 | 1990-11-05 | Asahi Glass Co Ltd | 2,2―ジフルオロ―3,4,5―トリヒドロキシカルボン酸誘導体の製造法 |
-
1994
- 1994-04-14 US US08/227,820 patent/US5428176A/en not_active Expired - Fee Related
-
1995
- 1995-04-12 FI FI951759A patent/FI951759A/fi unknown
- 1995-04-12 CA CA002146942A patent/CA2146942A1/en not_active Abandoned
- 1995-04-12 EP EP02018226A patent/EP1258486A3/en not_active Withdrawn
- 1995-04-12 TW TW084103538A patent/TW317567B/zh active
- 1995-04-12 EP EP95302423A patent/EP0677527B1/en not_active Expired - Lifetime
- 1995-04-12 HU HU9501061A patent/HU218118B/hu not_active IP Right Cessation
- 1995-04-12 ES ES95302423T patent/ES2166800T3/es not_active Expired - Lifetime
- 1995-04-12 EP EP99203391A patent/EP0970962A3/en not_active Ceased
- 1995-04-12 BR BR9501546A patent/BR9501546A/pt not_active Application Discontinuation
- 1995-04-12 KR KR1019950008472A patent/KR950032237A/ko not_active Application Discontinuation
- 1995-04-13 JP JP7088042A patent/JPH07285973A/ja not_active Withdrawn
- 1995-04-13 IL IL11335795A patent/IL113357A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
HU218118B (hu) | 2000-06-28 |
EP1258486A2 (en) | 2002-11-20 |
EP0677527A1 (en) | 1995-10-18 |
ES2166800T3 (es) | 2002-05-01 |
HUT71919A (en) | 1996-02-28 |
JPH07285973A (ja) | 1995-10-31 |
KR950032237A (ko) | 1995-12-20 |
IL113357A0 (en) | 1995-07-31 |
TW317567B (hu) | 1997-10-11 |
EP1258486A3 (en) | 2004-01-07 |
EP0677527B1 (en) | 2002-01-16 |
HU9501061D0 (en) | 1995-06-28 |
US5428176A (en) | 1995-06-27 |
FI951759A0 (fi) | 1995-04-12 |
EP0970962A3 (en) | 2001-04-11 |
FI951759A (fi) | 1995-10-15 |
EP0970962A2 (en) | 2000-01-12 |
BR9501546A (pt) | 1995-11-14 |
CA2146942A1 (en) | 1995-10-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |