IL112896A0 - Methods of using carboxylic acid esters to increase fetal-hemoglobin levels - Google Patents

Methods of using carboxylic acid esters to increase fetal-hemoglobin levels

Info

Publication number
IL112896A0
IL112896A0 IL11289695A IL11289695A IL112896A0 IL 112896 A0 IL112896 A0 IL 112896A0 IL 11289695 A IL11289695 A IL 11289695A IL 11289695 A IL11289695 A IL 11289695A IL 112896 A0 IL112896 A0 IL 112896A0
Authority
IL
Israel
Prior art keywords
methods
carboxylic acid
acid esters
hemoglobin levels
increase fetal
Prior art date
Application number
IL11289695A
Other languages
English (en)
Original Assignee
Rephaeli Ada
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rephaeli Ada filed Critical Rephaeli Ada
Publication of IL112896A0 publication Critical patent/IL112896A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225—Polycarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/265—Esters, e.g. nitroglycerine, selenocyanates of carbonic, thiocarbonic, or thiocarboxylic acids, e.g. thioacetic acid, xanthogenic acid, trithiocarbonic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pyrane Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IL11289695A 1994-03-07 1995-03-06 Methods of using carboxylic acid esters to increase fetal-hemoglobin levels IL112896A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/206,690 US5569675A (en) 1994-03-07 1994-03-07 Methods of using carboxylic acid esters to increase fetal-hemoglobin levels

Publications (1)

Publication Number Publication Date
IL112896A0 true IL112896A0 (en) 1995-06-29

Family

ID=22767519

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11289695A IL112896A0 (en) 1994-03-07 1995-03-06 Methods of using carboxylic acid esters to increase fetal-hemoglobin levels

Country Status (11)

Country Link
US (1) US5569675A (cs)
EP (1) EP0793488A1 (cs)
JP (1) JPH09510202A (cs)
KR (1) KR970701540A (cs)
CN (1) CN1148338A (cs)
AU (1) AU1980695A (cs)
BR (1) BR9507010A (cs)
CA (1) CA2184695A1 (cs)
IL (1) IL112896A0 (cs)
MX (1) MX9603885A (cs)
WO (1) WO1995024189A1 (cs)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5880152A (en) * 1995-10-06 1999-03-09 Vertex Pharmaceuticals, Inc. Butyrate prodrugs derived from lactic acid
US5912269A (en) * 1996-04-30 1999-06-15 Vertex Pharmaceuticals, Inc. Butyrate prodrugs derived from lactic acid
US5883123A (en) * 1995-10-06 1999-03-16 Vertex Pharmaceuticals, Inc. Butyrate prodrugs derived from lactic acid
US5827544A (en) * 1995-10-10 1998-10-27 The Arab Pharmaceutical Manufacturing Co. Ltd. Different way of management of neonatal hyperbilirubinemia
US5763488A (en) * 1995-10-30 1998-06-09 Vertex Pharmaceuticals Incorporated Methods and compositions using butyrate esters of threitol
CN1109545C (zh) * 1996-12-13 2003-05-28 科学与工业研究会 螯合铁的制剂及其制备方法
US6130248A (en) * 1996-12-30 2000-10-10 Bar-Ilan University Tricarboxylic acid-containing oxyalkyl esters and uses thereof
US6124495A (en) 1997-03-11 2000-09-26 Beacon Laboratories, Inc. Unsaturated oxyalkylene esters and uses thereof
US6110970A (en) * 1997-03-11 2000-08-29 Beacon Laboratories, Inc. Nitrogen-containing oxyalkylene esters and uses thereof
US5939455A (en) * 1997-03-11 1999-08-17 Beacon Laboratories, Inc. Therapeutic augmentation of oxyalkylene diesters and butyric acid derivatives
US6110955A (en) * 1997-03-11 2000-08-29 Beacon Laboratories, Inc. Metabolically stabilized oxyalkylene esters and uses thereof
US6030961A (en) * 1997-03-11 2000-02-29 Bar-Ilan Research & Development Co., Ltd. Oxyalkylene phosphate compounds and uses thereof
US6043389A (en) 1997-03-11 2000-03-28 Mor Research Applications, Ltd. Hydroxy and ether-containing oxyalkylene esters and uses thereof
US6822267B1 (en) * 1997-08-20 2004-11-23 Advantest Corporation Signal transmission circuit, CMOS semiconductor device, and circuit board
US6225350B1 (en) 1998-03-10 2001-05-01 Vertex Pharmaceuticals, Inc. Butyrate prodrugs derived from lactic acid
CN101574335A (zh) * 1999-02-05 2009-11-11 贝勒研究院 含七碳脂肪酸甘油三酯的营养补充剂或药物制剂
US20030162833A1 (en) 2001-08-01 2003-08-28 Roe Charles R. Fatty acid treatment for cardiac patients
US6693132B2 (en) 2000-12-21 2004-02-17 Beacon Laboratories, Inc. Methods for using alkanoyloxymethyl esters
US6720445B2 (en) 2000-12-21 2004-04-13 Beacon Laboratories, Inc. Acetyloxymethyl esters and methods for using the same
ITTO20020684A1 (it) * 2002-07-31 2004-02-01 Associazione Veneta Per La Lotta Alla Talassemia Nuovo uso dell'angelicina e di suoi analoghi strutturali.
US7154002B1 (en) 2002-10-08 2006-12-26 Takeda San Diego, Inc. Histone deacetylase inhibitors
KR20050122210A (ko) 2003-03-17 2005-12-28 다케다 샌디에고, 인코포레이티드 히스톤 탈아세틸화 효소 억제제
US20070042937A1 (en) * 2003-08-01 2007-02-22 Fibrogen, Inc. Inhibitors of 2-oxoglutarate dioxygenase as gamma globin inducers
EP1824831A2 (en) 2004-12-16 2007-08-29 Takeda San Diego, Inc. Histone deacetylase inhibitors
EP1896436A2 (en) 2005-05-11 2008-03-12 Takeda San Diego, Inc. Histone deacetylase inhibitors
BRPI0613429A2 (pt) 2005-07-14 2009-02-10 Takeda San Diego Inc inibidores de histona desacetilase
US20070185045A1 (en) * 2006-02-06 2007-08-09 Ratcliffe Peter J Inhibitors of 2-oxoglutarate dioxygenase as gamma globin inducers
JP2009536659A (ja) 2006-05-09 2009-10-15 ヘマクエスト・ファーマシューティカルズ，インコーポレーテッド 血液疾患の治療法
US9095565B2 (en) * 2006-05-09 2015-08-04 Phoenicia Biosciences, Inc. Methods for treating blood disorders
WO2007140335A2 (en) * 2006-05-25 2007-12-06 The Regents Of The University Of Michigan Screening methods and transgenic animals for treatment of beta-globin related diseases and conditions
WO2008088331A1 (en) * 2007-01-19 2008-07-24 Gloucester Pharmaceuticals Methods for increasing levels of human fetal hemoglobin
JP5753844B2 (ja) 2009-07-08 2015-07-22 ダーミラ（カナダ），インコーポレーテッド 皮膚疾患または病変の治療に有用なｔｏｆａ類似体
US9713602B1 (en) * 2016-03-15 2017-07-25 National Sun Yat-Sen University Method for facilitating the oxygen release of hemoglobin-based blood substitutes
EP3573618B1 (en) * 2017-01-30 2023-08-16 The Children's Hospital of Philadelphia Compositions and methods for hemoglobin production

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4822821A (en) * 1986-10-10 1989-04-18 Children's Hospital Medical Center Of Northern California Method for augmenting fetal hemoglobin
US5025029A (en) * 1986-10-10 1991-06-18 Children's Hospital Medical Center Of Northern California Method for augmenting fetal hemoglobin
DE3884517T2 (de) * 1987-07-30 1994-02-10 Kupat Holim Health Insurance Biologisch aktive Carbonsäureester.
US5216004A (en) * 1990-09-13 1993-06-01 Children's Hospital Medical Center Of North California Method for preventing malaria
US5439939A (en) * 1992-03-17 1995-08-08 Children's Hospital Medical Center Of Northern California Pharmaceutical compositions and methods using isobutyramide for treating betaglobin disorders
CA2175249A1 (en) * 1993-11-10 1995-05-18 Harold L. Newmark Butyric ester cyto-differentiating agents

Also Published As

Publication number Publication date
CA2184695A1 (en) 1995-09-14
MX9603885A (es) 1997-05-31
EP0793488A1 (en) 1997-09-10
KR970701540A (ko) 1997-04-12
US5569675A (en) 1996-10-29
CN1148338A (zh) 1997-04-23
WO1995024189A1 (en) 1995-09-14
BR9507010A (pt) 1997-09-16
AU1980695A (en) 1995-09-25
EP0793488A4 (cs) 1997-09-10
JPH09510202A (ja) 1997-10-14

Similar Documents

Publication Publication Date Title
IL112896A0 (en) Methods of using carboxylic acid esters to increase fetal-hemoglobin levels
HU9300776D0 (en) Carboxylic acid esters of rapamycine
PL331700A1 (en) Method of obtaining fatty acid esters
FI963867A7 (fi) Rasvahappoestereiden käyttö bioadhesiivisina aineina
IL103817A0 (en) Method and intermediates for the preparation of prolineboronic acid esters
IL124551A0 (en) Aqueous suspensions of 9-hydroxyrispridone fatty acid esters
PH29944A (en) Washing composition constaining fatty acid esters
ZA945189B (en) Sulfonation of fatty acid esters
GB8719886D0 (en) Carboxylic acid esters/acids
IL115594A0 (en) Preparation of alpha-tertiary carboxylic acid esters
GB8425221D0 (en) Preparation of carboxylic acid esters
DE3569931D1 (en) Carboxylic acid ester derivatives of deglucoteicoplanin
FI881959L (fi) Karboksyylihappoestereiden pelkistys
JPS6471838A (en) Manufacture of carboxylic acid ester
JPS5742658A (en) Pentafluorobenzyl esters of phenylcycloalkane carboxylic acid
GB2264708B (en) Carboxylic acid esters of hydroxyphenylalkanols as stabilisers
PL317787A1 (en) Method of obtaining sillyl carboxylic esters
EP0512848A3 (en) Enzymatic resolution of alpha-tertiary carboxylic acid esters
PL246322A1 (en) Method of obtaining optically active alpha-chiral carboxylic acid esters
HUP9802187A3 (en) Method of producing 3-pentenic acid esters by carbonylation of alkoxynutenes
IL122919A0 (en) Preparation of 1-alkyl-pyrazole-5-carboxylic acid esters
GB8427816D0 (en) Esterification of carboxylic acid
ZA933849B (en) Novel thiosemicarbazonic acid esters
ZA882951B (en) Reduction of carboxylic esters
ZA9711058B (en) Production of organic carboxylic acid esters