IL112641A - Broad spectrum antimicrobial compounds and pharmaceutical compositions containing them - Google Patents

Broad spectrum antimicrobial compounds and pharmaceutical compositions containing them

Info

Publication number
IL112641A
IL112641A IL11264195A IL11264195A IL112641A IL 112641 A IL112641 A IL 112641A IL 11264195 A IL11264195 A IL 11264195A IL 11264195 A IL11264195 A IL 11264195A IL 112641 A IL112641 A IL 112641A
Authority
IL
Israel
Prior art keywords
indolicidin
broad spectrum
survival
growth
pharmaceutical compositions
Prior art date
Application number
IL11264195A
Other languages
English (en)
Other versions
IL112641A0 (en
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Publication of IL112641A0 publication Critical patent/IL112641A0/xx
Publication of IL112641A publication Critical patent/IL112641A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IL11264195A 1994-02-16 1995-02-14 Broad spectrum antimicrobial compounds and pharmaceutical compositions containing them IL112641A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/197,205 US5547939A (en) 1991-06-14 1994-02-16 Broad spectrum antimicrobial compounds and methods of use

Publications (2)

Publication Number Publication Date
IL112641A0 IL112641A0 (en) 1995-05-26
IL112641A true IL112641A (en) 2000-07-26

Family

ID=22728460

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11264195A IL112641A (en) 1994-02-16 1995-02-14 Broad spectrum antimicrobial compounds and pharmaceutical compositions containing them

Country Status (14)

Country Link
US (1) US5547939A (de)
EP (1) EP0750506B1 (de)
JP (2) JP3147904B2 (de)
AT (1) ATE200426T1 (de)
AU (1) AU683725B2 (de)
CA (1) CA2179286C (de)
DE (1) DE69520668T2 (de)
DK (1) DK0750506T3 (de)
ES (1) ES2155518T3 (de)
GR (1) GR3036092T3 (de)
IL (1) IL112641A (de)
PT (1) PT750506E (de)
WO (1) WO1995022338A1 (de)
ZA (1) ZA951276B (de)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5646119A (en) * 1991-11-01 1997-07-08 Periodontix, Inc. D-amino acid histatin-based peptides as anti-fungal and anti-bacterial agents
US5885965A (en) * 1991-11-01 1999-03-23 Periodontix, Inc. Anti-fungal D-amino acid histatin-based peptides
DE69637731D1 (de) * 1995-08-23 2008-12-11 Univ British Columbia Antimikrobielle kationische peptide und methoden zu ihrer identifizierung
US6042848A (en) * 1996-08-15 2000-03-28 The Board Of Trustees Of Southern Illinois University Enhancement of antimicrobial peptide activity by metal ions
EP1174439B1 (de) * 1996-08-21 2008-10-08 Migenix Inc. Zusammensetzungen und Methoden zur Behandlung von Infektionen unter Verwendung von Indolicidinanalogen
US6180604B1 (en) 1996-08-21 2001-01-30 Micrologix Biotech Inc. Compositions and methods for treating infections using analogues of indolicidin
US6503881B2 (en) * 1996-08-21 2003-01-07 Micrologix Biotech Inc. Compositions and methods for treating infections using cationic peptides alone or in combination with antibiotics
WO1999043357A1 (en) * 1998-02-25 1999-09-02 Micrologix Biotech Inc. Indolicidin and cationic peptides conjugated with polymers
SE9801495D0 (sv) * 1998-04-28 1998-04-28 Astra Ab Protein formulationa
US6303575B1 (en) * 1998-05-12 2001-10-16 The Regents Of The University Of California Indolicidin analogs and methods of using same
WO1999065506A2 (en) * 1998-06-12 1999-12-23 Micrologix Biotech Inc. Cancer therapy with indolicidin or cationic peptides and their polymer conjugates
US6444645B1 (en) 1998-06-18 2002-09-03 The Regents Of The University Of California Crosslink-stabilized indolicidin analogs
GB9818938D0 (en) * 1998-08-28 1998-10-21 Alpharma As Bioactive peptides
US6096225A (en) * 1998-09-11 2000-08-01 Nalco Chemical Company Method of controlling biofouling in aqueous media using antimicrobial emulsions
WO2000026344A1 (en) * 1998-10-30 2000-05-11 Interlink Biotechnologies Llc Peptides with enhanced stability to protease degradation
US6335318B1 (en) 1999-05-10 2002-01-01 The Regents Of The University Of California Antimicrobial theta defensins and methods of using same
US6482799B1 (en) 1999-05-25 2002-11-19 The Regents Of The University Of California Self-preserving multipurpose ophthalmic solutions incorporating a polypeptide antimicrobial
GB0005702D0 (en) * 2000-03-09 2000-05-03 Alpharma As Method
EP1259635A4 (de) * 2000-02-25 2004-11-24 Smithkline Beecham Corp Verfahren zum screenen von antimikrobiellen verbindungen
GB0005703D0 (en) * 2000-03-09 2000-05-03 Alpharma As Compounds
NZ522225A (en) * 2000-04-26 2004-06-25 Wisconsin Alumni Res Found Triaryl cation antibiotics from environmental DNA
US6835536B2 (en) 2001-08-21 2004-12-28 Micrologix Biotech Inc. Antimicrobial cationic peptides and formulations thereof
US8933029B2 (en) * 2001-08-24 2015-01-13 Carrus Capital Corporation Antimicrobial and anti-inflammatory peptides
AU2003231471A1 (en) * 2002-04-25 2003-11-10 Toagosei Co., Ltd. Antimicrobial polypeptide and utizliation thereof
US7119070B2 (en) * 2002-04-30 2006-10-10 The Regents Of The University Of California Antimicrobial theta defensins, analogs thereof, and methods of use
US20030040032A1 (en) * 2002-08-23 2003-02-27 Demarsh Peter L. Methods of screening for antimicrobial compounds
US7674771B2 (en) * 2003-10-29 2010-03-09 Toagosei Co., Ltd Antimicrobial peptides and utilization of the same
JP4507080B2 (ja) * 2004-07-30 2010-07-21 東亞合成株式会社 抗菌ペプチド及びその利用
JP4730584B2 (ja) * 2004-12-06 2011-07-20 東亞合成株式会社 抗菌ペプチド及びその利用
US20080255052A1 (en) * 2004-12-23 2008-10-16 The Regents Of The University Of California Immunologic regulation by theta defensins
EP1849474B1 (de) * 2005-02-15 2016-09-07 Toagosei Co., Ltd. Antimikrobielles peptid und verwendung davon
ES2497441T3 (es) 2006-08-21 2014-09-22 The University Of British Columbia Péptidos inmunomoduladores catiónicos pequeños
US8784659B2 (en) * 2007-08-08 2014-07-22 General Electric Company Method for controlling microbial biofilm in aqueous systems
US7785478B2 (en) * 2007-08-08 2010-08-31 General Electric Company Method for controlling protozoa that harbor bacteria
US20110052655A1 (en) * 2007-08-08 2011-03-03 Wilson Kurt Whitekettle Methods and vesicles for controlling protozoa
US7824557B2 (en) * 2007-08-08 2010-11-02 General Electric Company Method for controlling microbial biofilm in aqueous systems
US11918624B2 (en) 2020-06-10 2024-03-05 Kelsius Laboratories LLC Therapeutic composition for use in the treatment of COVID-19 and other cytokine storm associated disorders
WO2026042045A1 (en) 2024-08-22 2026-02-26 Itc Limited Indolicidine-containing compositions for personal care/hygiene applications
WO2026041925A1 (en) 2024-08-22 2026-02-26 Itc Limited A synergistic composition of an antimicrobial peptide (amp) and natural active

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4543252A (en) * 1982-01-21 1985-09-24 The Regents Of The University Of California Cationic oligopeptides having microbicidal activity
US5324716A (en) * 1991-06-14 1994-06-28 Regents Of The University Of California Broad spectrum antimicrobial compounds and methods of use

Also Published As

Publication number Publication date
GR3036092T3 (en) 2001-09-28
WO1995022338A1 (en) 1995-08-24
EP0750506A1 (de) 1997-01-02
IL112641A0 (en) 1995-05-26
DK0750506T3 (da) 2001-05-07
JPH09509175A (ja) 1997-09-16
DE69520668T2 (de) 2001-09-06
JP2001172297A (ja) 2001-06-26
AU1747895A (en) 1995-09-04
CA2179286A1 (en) 1995-08-24
JP3147904B2 (ja) 2001-03-19
EP0750506A4 (de) 1998-10-14
ZA951276B (en) 1995-10-23
CA2179286C (en) 1999-09-21
PT750506E (pt) 2001-09-28
ATE200426T1 (de) 2001-04-15
EP0750506B1 (de) 2001-04-11
DE69520668D1 (de) 2001-05-17
ES2155518T3 (es) 2001-05-16
US5547939A (en) 1996-08-20
AU683725B2 (en) 1997-11-20

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Legal Events

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KB Patent renewed