IL110755A - In vitro growth of neutrophil and megakaryocyte precursors in serum-free media - Google Patents
In vitro growth of neutrophil and megakaryocyte precursors in serum-free mediaInfo
- Publication number
- IL110755A IL110755A IL11075594A IL11075594A IL110755A IL 110755 A IL110755 A IL 110755A IL 11075594 A IL11075594 A IL 11075594A IL 11075594 A IL11075594 A IL 11075594A IL 110755 A IL110755 A IL 110755A
- Authority
- IL
- Israel
- Prior art keywords
- neutrophil
- serum
- free media
- vitro growth
- megakaryocyte precursors
- Prior art date
Links
- 238000000338 in vitro Methods 0.000 title 1
- 210000003593 megakaryocyte Anatomy 0.000 title 1
- 210000000440 neutrophil Anatomy 0.000 title 1
- 239000002243 precursor Substances 0.000 title 1
- 239000004017 serum-free culture medium Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0644—Platelets; Megakaryocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0642—Granulocytes, e.g. basopils, eosinophils, neutrophils, mast cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
- C12N2500/24—Iron; Fe chelators; Transferrin
- C12N2500/25—Insulin-transferrin; Insulin-transferrin-selenium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/36—Lipids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/44—Thiols, e.g. mercaptoethanol
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/98—Xeno-free medium and culture conditions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/125—Stem cell factor [SCF], c-kit ligand [KL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/22—Colony stimulating factors (G-CSF, GM-CSF)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/38—Hormones with nuclear receptors
- C12N2501/39—Steroid hormones
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biotechnology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Control Of Transmission Device (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11027793A | 1993-08-23 | 1993-08-23 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL110755A0 IL110755A0 (en) | 1994-11-11 |
| IL110755A true IL110755A (en) | 2000-11-21 |
Family
ID=22332160
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL11075594A IL110755A (en) | 1993-08-23 | 1994-08-23 | In vitro growth of neutrophil and megakaryocyte precursors in serum-free media |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0719326A1 (en) |
| JP (1) | JPH09505462A (en) |
| AU (1) | AU702871B2 (en) |
| CA (1) | CA2168091A1 (en) |
| IL (1) | IL110755A (en) |
| SG (1) | SG52619A1 (en) |
| WO (1) | WO1995006112A1 (en) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7144731B2 (en) | 1989-10-16 | 2006-12-05 | Amgen Inc. | SCF antibody compositions and methods of using the same |
| US6248319B1 (en) | 1989-10-16 | 2001-06-19 | Krisztina M. Zsebo | Method for increasing hematopoietic progenitor cells by stem cell factor polypeptides |
| US6852313B1 (en) | 1989-10-16 | 2005-02-08 | Amgen Inc. | Method of stimulating growth of melanocyte cells by administering stem cell factor |
| US6207454B1 (en) | 1989-10-16 | 2001-03-27 | Amgen Inc. | Method for enhancing the effciency of gene transfer with stem cell factor (SCF) polypeptide |
| US9068164B1 (en) * | 1995-02-02 | 2015-06-30 | Tristem Trading (Cyprus) Limited | Method of preparing an undifferentiated cell |
| WO1996040866A1 (en) * | 1995-06-07 | 1996-12-19 | Novartis Ag | Serum-free media for primitive hematopoietic cells and methods of use thereof |
| EP0891419A4 (en) * | 1996-03-12 | 2000-03-01 | Life Technologies Inc | ADDITIVE FOR NUTRITIVE CULTURE MEDIA FOR HEMATOPOIETIC CELLS |
| WO1998008934A1 (en) | 1996-08-30 | 1998-03-05 | Life Technologies, Inc. | Serum-free mammalian cell culture medium, and uses thereof |
| US5945337A (en) | 1996-10-18 | 1999-08-31 | Quality Biological, Inc. | Method for culturing CD34+ cells in a serum-free medium |
| US6811776B2 (en) | 2000-12-27 | 2004-11-02 | The Regents Of The University Of Michigan | Process for ex vivo formation of mammalian bone and uses thereof |
| DE602004026917D1 (en) | 2003-12-26 | 2010-06-10 | Makoto Asashima | BASE MEDIUM FOR CULTIVATING ES CELLS |
| JP4651282B2 (en) * | 2004-01-21 | 2011-03-16 | 田辺三菱製薬株式会社 | Method for amplifying hematopoietic stem cells and hematopoietic progenitor cells |
| US7923013B2 (en) | 2004-12-28 | 2011-04-12 | The Rockefeller University | Glycolipids and analogues thereof as antigens for NKT cells |
| WO2006071848A2 (en) | 2004-12-28 | 2006-07-06 | The Rockefeller University | Glycolipids and analogues thereof as antigens for nk t cells |
| US7837990B2 (en) | 2005-03-28 | 2010-11-23 | The Rockefeller University | In vivo expanded NKT cells and methods of use thereof |
| AU2015207905B2 (en) * | 2006-03-24 | 2017-04-27 | Children's Medical Center Corporation | Method to modulate hematopoietic stem cell growth |
| WO2007112084A2 (en) | 2006-03-24 | 2007-10-04 | Children's Medical Center Corporation | Method to modulate hematopoietic stem cell growth |
| AU2013202353B2 (en) * | 2006-03-24 | 2015-05-07 | Children's Medical Center Corporation | Method to modulate hematopoietic stem cell growth |
| US9402852B2 (en) | 2006-10-20 | 2016-08-02 | Children's Medical Center Corporation | Method to enhance tissue regeneration |
| US9056085B2 (en) | 2009-02-03 | 2015-06-16 | Children's Medical Center Corporation | Methods for enhancing hematopoietic stem/progenitor cell engraftment |
| WO2010091052A2 (en) | 2009-02-03 | 2010-08-12 | Children's Medical Center Corporation | Methods for enhancing hematopoietic stem/progenitor cell engraftment |
| WO2013006806A1 (en) * | 2011-07-06 | 2013-01-10 | Cellerant Therapeutics, Inc. | Megakaryocyte progenitor cells for production of platelets |
| CN112410298A (en) | 2011-12-02 | 2021-02-26 | 菲特治疗公司 | Enhanced stem cell compositions |
| EP2785350B1 (en) | 2011-12-02 | 2018-05-02 | Fate Therapeutics, Inc. | Improved methods of treating ischemia |
| WO2013184809A1 (en) * | 2012-06-05 | 2013-12-12 | The Regents Of The University Of California | Methods and compositions for the rapid production of retinal pigmented epithelial cells from pluripotent cells |
| WO2014150602A1 (en) | 2013-03-15 | 2014-09-25 | Fate Therapeutics, Inc. | Cell potency assay for therapeutic potential |
| JP7521738B2 (en) * | 2020-05-18 | 2024-07-24 | キヤノン株式会社 | Method for producing target cells, method for producing product by target cells, and serum-free medium |
| CA3192530A1 (en) * | 2020-09-21 | 2022-03-24 | Xiaoming Chen | Aqueous pharmaceutical formulation of hydrocortisone sodium phosphate and monothioglycerol |
| FR3128874B1 (en) * | 2021-11-09 | 2025-04-18 | Crossject | Hydrocortisone Pharmaceutical Solution for Injection Device |
| WO2025018336A1 (en) * | 2023-07-20 | 2025-01-23 | 学校法人近畿大学 | Serum-free medium |
| CN120642821A (en) * | 2025-06-20 | 2025-09-16 | 北京医院 | Culture method and composition for synergistically prolonging in-vitro survival time of neutrophils |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816401A (en) * | 1985-09-09 | 1989-03-28 | University Of Rochester | Serum free cell culture medium |
| US5004681B1 (en) * | 1987-11-12 | 2000-04-11 | Biocyte Corp | Preservation of fetal and neonatal hematopoietic stem and progenitor cells of the blood |
| CA2069879A1 (en) * | 1990-10-05 | 1992-04-06 | George Tidmarsh | Megakaryocyte and platelet growth, production and composition |
-
1994
- 1994-08-23 IL IL11075594A patent/IL110755A/en not_active IP Right Cessation
- 1994-08-23 WO PCT/US1994/009622 patent/WO1995006112A1/en not_active Ceased
- 1994-08-23 AU AU76744/94A patent/AU702871B2/en not_active Ceased
- 1994-08-23 JP JP7507759A patent/JPH09505462A/en active Pending
- 1994-08-23 SG SG1996006929A patent/SG52619A1/en unknown
- 1994-08-23 CA CA002168091A patent/CA2168091A1/en not_active Abandoned
- 1994-08-23 EP EP94927235A patent/EP0719326A1/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| SG52619A1 (en) | 1998-09-28 |
| AU7674494A (en) | 1995-03-21 |
| AU702871B2 (en) | 1999-03-11 |
| WO1995006112A1 (en) | 1995-03-02 |
| CA2168091A1 (en) | 1995-03-02 |
| EP0719326A1 (en) | 1996-07-03 |
| IL110755A0 (en) | 1994-11-11 |
| JPH09505462A (en) | 1997-06-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| MM9K | Patent not in force due to non-payment of renewal fees |