IL109866A - Crystalline 3-(4-hexyloxy-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyridine(+)L-hydrogentartrate its preparation and pharmaceutical compositions containing it - Google Patents

Crystalline 3-(4-hexyloxy-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyridine(+)L-hydrogentartrate its preparation and pharmaceutical compositions containing it

Info

Publication number
IL109866A
IL109866A IL10986694A IL10986694A IL109866A IL 109866 A IL109866 A IL 109866A IL 10986694 A IL10986694 A IL 10986694A IL 10986694 A IL10986694 A IL 10986694A IL 109866 A IL109866 A IL 109866A
Authority
IL
Israel
Prior art keywords
hydrogentartrate
thiadiazol
methylpyridine
hexyloxy
tetrahydro
Prior art date
Application number
IL10986694A
Other languages
English (en)
Other versions
IL109866A0 (en
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of IL109866A0 publication Critical patent/IL109866A0/xx
Publication of IL109866A publication Critical patent/IL109866A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL10986694A 1993-06-04 1994-06-02 Crystalline 3-(4-hexyloxy-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyridine(+)L-hydrogentartrate its preparation and pharmaceutical compositions containing it IL109866A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7257293A 1993-06-04 1993-06-04

Publications (2)

Publication Number Publication Date
IL109866A0 IL109866A0 (en) 1994-10-07
IL109866A true IL109866A (en) 2000-06-01

Family

ID=22108479

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10986694A IL109866A (en) 1993-06-04 1994-06-02 Crystalline 3-(4-hexyloxy-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyridine(+)L-hydrogentartrate its preparation and pharmaceutical compositions containing it

Country Status (22)

Country Link
US (1) US5834495A (cs)
EP (1) EP0703915B1 (cs)
JP (1) JP3190679B2 (cs)
KR (1) KR100339115B1 (cs)
CN (1) CN1064681C (cs)
AT (1) ATE196631T1 (cs)
AU (1) AU698673B2 (cs)
CA (1) CA2164296C (cs)
CZ (1) CZ290550B6 (cs)
DE (1) DE69426021T2 (cs)
DK (1) DK0703915T3 (cs)
ES (1) ES2152315T3 (cs)
FI (1) FI955829A0 (cs)
GR (1) GR3035033T3 (cs)
HU (1) HUT75038A (cs)
IL (1) IL109866A (cs)
NO (1) NO305560B1 (cs)
NZ (2) NZ267062A (cs)
PT (1) PT703915E (cs)
SK (1) SK281980B6 (cs)
WO (1) WO1994029303A1 (cs)
ZA (1) ZA943904B (cs)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6090829A (en) * 1996-08-01 2000-07-18 Eli Lilly And Company Method for treating excessive aggression
US6117890A (en) * 1996-08-01 2000-09-12 Eli Lilly And Company Method for treating bipolar disorder
US6043258A (en) * 1996-08-01 2000-03-28 Eli Lilly And Company Method for treating disruptive behavior disorders with xanomeline
EP0821956A1 (en) * 1996-08-01 1998-02-04 Eli Lilly And Company Method for treating disruptive behavior disorders
EP0821954A1 (en) * 1996-08-01 1998-02-04 Eli Lilly And Company Method for treating mental retardation
US6034108A (en) * 1997-07-28 2000-03-07 Eli Lilly And Company Method for treating mental retardation
CA2978201A1 (en) * 2015-03-06 2016-09-15 Chase Pharmaceuticals Corporation Use of oxybutynin transdermal formulations to reduce side effects associated with muscarinic agonists
CN115974863B (zh) * 2021-10-14 2024-12-31 南京迈诺威医药科技有限公司 占诺美林衍生物的苹果酸盐、a晶型及其制备方法和用途
US12269818B2 (en) 2023-04-24 2025-04-08 Terran Biosciences Inc. Analogs of xanomeline

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5043345A (en) * 1989-02-22 1991-08-27 Novo Nordisk A/S Piperidine compounds and their preparation and use
US5260311A (en) * 1989-02-22 1993-11-09 Novo Nordisk A/S Piperidine compounds and their use
US5264444A (en) * 1989-02-22 1993-11-23 Novo Nordisk A/S Piperidine compounds and use

Also Published As

Publication number Publication date
DE69426021D1 (de) 2000-11-02
FI955829A7 (fi) 1995-12-04
KR960702835A (ko) 1996-05-23
EP0703915B1 (en) 2000-09-27
NZ336733A (en) 2001-02-23
NZ267062A (en) 1999-09-29
WO1994029303A1 (en) 1994-12-22
PT703915E (pt) 2001-03-30
ES2152315T3 (es) 2001-02-01
HUT75038A (en) 1997-03-28
EP0703915A1 (en) 1996-04-03
CA2164296A1 (en) 1994-12-22
JPH08511008A (ja) 1996-11-19
FI955829L (fi) 1995-12-04
SK152095A3 (en) 1996-10-02
AU6924294A (en) 1995-01-03
CZ321095A3 (en) 1996-09-11
CZ290550B6 (cs) 2002-08-14
GR3035033T3 (en) 2001-03-30
NO954892D0 (no) 1995-12-01
US5834495A (en) 1998-11-10
CN1064681C (zh) 2001-04-18
CN1128999A (zh) 1996-08-14
FI955829A0 (fi) 1995-12-04
ATE196631T1 (de) 2000-10-15
KR100339115B1 (ko) 2002-11-07
DK0703915T3 (da) 2001-01-22
IL109866A0 (en) 1994-10-07
ZA943904B (en) 1995-12-04
SK281980B6 (sk) 2001-09-11
DE69426021T2 (de) 2001-05-17
CA2164296C (en) 2007-01-23
AU698673B2 (en) 1998-11-05
HU9503453D0 (en) 1996-01-29
NO305560B1 (no) 1999-06-21
NO954892L (no) 1995-12-01
JP3190679B2 (ja) 2001-07-23

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees