IL107934A0 - Formation of triple helix complexes - Google Patents

Formation of triple helix complexes

Info

Publication number
IL107934A0
IL107934A0 IL10793493A IL10793493A IL107934A0 IL 107934 A0 IL107934 A0 IL 107934A0 IL 10793493 A IL10793493 A IL 10793493A IL 10793493 A IL10793493 A IL 10793493A IL 107934 A0 IL107934 A0 IL 107934A0
Authority
IL
Israel
Prior art keywords
formation
triple helix
helix complexes
complexes
triple
Prior art date
Application number
IL10793493A
Other languages
English (en)
Original Assignee
Genta Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genta Inc filed Critical Genta Inc
Publication of IL107934A0 publication Critical patent/IL107934A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6839—Triple helix formation or other higher order conformations in hybridisation assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/15—Nucleic acids forming more than 2 strands, e.g. TFOs
    • C12N2310/152—Nucleic acids forming more than 2 strands, e.g. TFOs on a single-stranded target, e.g. fold-back TFOs
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/35—Nature of the modification
    • C12N2310/352—Nature of the modification linked to the nucleic acid via a carbon atom
    • C12N2310/3521—Methyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL10793493A 1992-12-08 1993-12-08 Formation of triple helix complexes IL107934A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US98774692A 1992-12-08 1992-12-08

Publications (1)

Publication Number Publication Date
IL107934A0 true IL107934A0 (en) 1994-04-12

Family

ID=25533520

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10793493A IL107934A0 (en) 1992-12-08 1993-12-08 Formation of triple helix complexes

Country Status (8)

Country Link
EP (1) EP0673260A4 (fr)
JP (1) JPH08504103A (fr)
KR (1) KR950704002A (fr)
AU (1) AU684774B2 (fr)
CA (1) CA2151263A1 (fr)
IL (1) IL107934A0 (fr)
NZ (1) NZ259223A (fr)
WO (1) WO1994013326A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6441130B1 (en) 1991-05-24 2002-08-27 Isis Pharmaceuticals, Inc. Linked peptide nucleic acids
US6451968B1 (en) 1991-05-24 2002-09-17 Isis Pharmaceuticals, Inc. Peptide nucleic acids
WO1994018835A1 (fr) * 1993-02-19 1994-09-01 Genta Incorporated Traitement de la calvitie associee aux androgenes au moyen d'oligomeres antisens
DE19842527A1 (de) * 1998-09-18 2000-03-23 Friedrich Schiller Uni Jena Bu Verfahren zur Bildung tripelhelixbildender Oligomere und deren Verbindungen

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2006008C (fr) * 1988-12-20 2000-02-15 Donald J. Kessler Methode pour obtenir des oligonucleotides synthetiques qui se lient specifiquement a des sites cibles sur des molecules d'adn double brin, en formant un triplex colineaire; methode d'utilisation de ces oligonucleotides synthetiques
US5176996A (en) * 1988-12-20 1993-01-05 Baylor College Of Medicine Method for making synthetic oligonucleotides which bind specifically to target sites on duplex DNA molecules, by forming a colinear triplex, the synthetic oligonucleotides and methods of use
US5399676A (en) * 1989-10-23 1995-03-21 Gilead Sciences Oligonucleotides with inverted polarity
HUT66828A (en) * 1991-03-27 1995-01-30 Res Corp Technologies Inc Single-stranded circular oligonucleotides

Also Published As

Publication number Publication date
AU684774B2 (en) 1998-01-08
NZ259223A (en) 1997-10-24
WO1994013326A1 (fr) 1994-06-23
AU6654094A (en) 1994-07-04
JPH08504103A (ja) 1996-05-07
EP0673260A1 (fr) 1995-09-27
EP0673260A4 (fr) 1999-04-14
CA2151263A1 (fr) 1994-06-23
KR950704002A (ko) 1995-11-17

Similar Documents

Publication Publication Date Title
AU3700893A (en) Helix resonator
ZA935378B (en) Anti-inflammatory compounds
IL107960A0 (en) Production of azadirachten
GB9212410D0 (en) Production of difluoromethane
IL107934A0 (en) Formation of triple helix complexes
GB9311742D0 (en) Production of hydrofluoroalkanes
GB9114971D0 (en) Triple mode microwave filter
GB2268183B (en) Asymmetrical 1:2 metal complexes of azo compounds
GB9306939D0 (en) Pie manufacture
GB9226309D0 (en) Improved method of manufacture
GB2260089B (en) Brick manufacture
GB9200790D0 (en) Manufacture of elongate superconductors
HU9203546D0 (en) Drawplate of double profile
EP0553954A3 (en) Preparation of tetramethyldiamino-polyoxyethylenes
GB9211573D0 (en) Compounds capable of forming inclusion complexes
GB9225390D0 (en) Production of pentafluorethane
ZA921841B (en) Manufacture of cables
KR0115462Y1 (en) Center lead of magnetron
MY108453A (en) Can manufacture
GB9223161D0 (en) Anti-inflammatory compounds
GB9203512D0 (en) Anti-inflammatory compounds
GB9216682D0 (en) Anti-inflammatory compounds
AU4530997A (en) Glycosylation-mediated inhibition of factor X
GB9217966D0 (en) Production of tetrafluoroethanes
GB9217965D0 (en) Production of tetrafluoroethanes