IL107251A0 - 3,3-Disubstituted tri- and tetracyclic indolin-2-ones and pharmaceutical compositions comprising them - Google Patents

3,3-Disubstituted tri- and tetracyclic indolin-2-ones and pharmaceutical compositions comprising them

Info

Publication number
IL107251A0
IL107251A0 IL107251A IL10725193A IL107251A0 IL 107251 A0 IL107251 A0 IL 107251A0 IL 107251 A IL107251 A IL 107251A IL 10725193 A IL10725193 A IL 10725193A IL 107251 A0 IL107251 A0 IL 107251A0
Authority
IL
Israel
Prior art keywords
indolin
tetracyclic
disubstituted
tri
ones
Prior art date
Application number
IL107251A
Other languages
English (en)
Original Assignee
Du Pont Merck Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont Merck Pharma filed Critical Du Pont Merck Pharma
Publication of IL107251A0 publication Critical patent/IL107251A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/06—Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL107251A 1992-10-13 1993-10-12 3,3-Disubstituted tri- and tetracyclic indolin-2-ones and pharmaceutical compositions comprising them IL107251A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US96052292A 1992-10-13 1992-10-13

Publications (1)

Publication Number Publication Date
IL107251A0 true IL107251A0 (en) 1994-01-25

Family

ID=25503278

Family Applications (1)

Application Number Title Priority Date Filing Date
IL107251A IL107251A0 (en) 1992-10-13 1993-10-12 3,3-Disubstituted tri- and tetracyclic indolin-2-ones and pharmaceutical compositions comprising them

Country Status (8)

Country Link
EP (1) EP0664810A1 (xx)
JP (1) JPH08502293A (xx)
AU (1) AU6242294A (xx)
CA (1) CA2146000A1 (xx)
IL (1) IL107251A0 (xx)
MX (1) MX9306337A (xx)
WO (1) WO1994009009A1 (xx)
ZA (1) ZA937604B (xx)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112624972A (zh) * 2019-09-24 2021-04-09 中国人民解放军军事科学院军事医学研究院 吖啶酮类化合物及医药用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4760083A (en) * 1986-04-10 1988-07-26 E. I. Dupont De Nemours & Company 3,3-disubstituted indolines
US5173489A (en) * 1986-04-10 1992-12-22 The Dupont Merck Pharmaceutical Co. α,α-disubstituted aromatics and heteroaromatics as cognition enhancers
US5278045A (en) * 1990-02-28 1994-01-11 Du Pont Merck Pharmaceutical Company Method and compositions to screen compounds for enhancement of the cholinergic, dopaminergic and serotonergic function

Also Published As

Publication number Publication date
AU6242294A (en) 1994-05-09
MX9306337A (es) 1995-01-31
EP0664810A1 (en) 1995-08-02
ZA937604B (en) 1995-04-13
JPH08502293A (ja) 1996-03-12
CA2146000A1 (en) 1994-04-28
WO1994009009A1 (en) 1994-04-28

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