IL107050A - Use of an active section or active analog of collagen for the preparation of a drug for the treatment of rheumatoid arthritis - Google Patents
Use of an active section or active analog of collagen for the preparation of a drug for the treatment of rheumatoid arthritisInfo
- Publication number
- IL107050A IL107050A IL10705093A IL10705093A IL107050A IL 107050 A IL107050 A IL 107050A IL 10705093 A IL10705093 A IL 10705093A IL 10705093 A IL10705093 A IL 10705093A IL 107050 A IL107050 A IL 107050A
- Authority
- IL
- Israel
- Prior art keywords
- collagen
- type
- arthritis
- medicament
- treatment
- Prior art date
Links
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- 229910052753 mercury Inorganic materials 0.000 description 1
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- 239000006199 nebulizer Substances 0.000 description 1
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- 239000008203 oral pharmaceutical composition Substances 0.000 description 1
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- 239000011886 peripheral blood Substances 0.000 description 1
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- 239000002953 phosphate buffered saline Substances 0.000 description 1
- 229960002702 piroxicam Drugs 0.000 description 1
- 239000000902 placebo Substances 0.000 description 1
- 229940068196 placebo Drugs 0.000 description 1
- 210000002826 placenta Anatomy 0.000 description 1
- 208000030428 polyarticular arthritis Diseases 0.000 description 1
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- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229960004618 prednisone Drugs 0.000 description 1
- XOFYZVNMUHMLCC-ZPOLXVRWSA-N prednisone Chemical compound O=C1C=C[C@]2(C)[C@H]3C(=O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 XOFYZVNMUHMLCC-ZPOLXVRWSA-N 0.000 description 1
- 208000037821 progressive disease Diseases 0.000 description 1
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- 230000002685 pulmonary effect Effects 0.000 description 1
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- 230000001235 sensitizing effect Effects 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000008247 solid mixture Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- MLKXDPUZXIRXEP-MFOYZWKCSA-N sulindac Chemical compound CC1=C(CC(O)=O)C2=CC(F)=CC=C2\C1=C/C1=CC=C(S(C)=O)C=C1 MLKXDPUZXIRXEP-MFOYZWKCSA-N 0.000 description 1
- 229960000894 sulindac Drugs 0.000 description 1
- 230000008093 supporting effect Effects 0.000 description 1
- 239000000375 suspending agent Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 201000004595 synovitis Diseases 0.000 description 1
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- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 210000002435 tendon Anatomy 0.000 description 1
- 230000003614 tolerogenic effect Effects 0.000 description 1
- 210000004127 vitreous body Anatomy 0.000 description 1
- 229940063674 voltaren Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/542—Mucosal route oral/gastrointestinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/543—Mucosal route intranasal
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Rheumatology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Biomedical Technology (AREA)
- Rehabilitation Therapy (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Marine Sciences & Fisheries (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/951,565 US5399347A (en) | 1987-06-24 | 1992-09-25 | Method of treating rheumatoid arthritis with type II collagen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL107050A0 IL107050A0 (en) | 1993-12-28 |
| IL107050A true IL107050A (en) | 1999-12-31 |
Family
ID=25491835
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL10705093A IL107050A (en) | 1992-09-25 | 1993-09-20 | Use of an active section or active analog of collagen for the preparation of a drug for the treatment of rheumatoid arthritis |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US5399347A (fr) |
| AU (1) | AU5439994A (fr) |
| IL (1) | IL107050A (fr) |
| WO (1) | WO1994007520A1 (fr) |
Families Citing this family (75)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5849298A (en) * | 1987-06-24 | 1998-12-15 | Autoimmune Inc. | Treatment of multiple sclerosis by oral administration of bovine myelin |
| US5843445A (en) * | 1987-06-24 | 1998-12-01 | Autoimmune, Inc. | Method of treating rheumatoid arthritis with type II collagen |
| IL99699A (en) | 1990-10-10 | 2002-04-21 | Autoimmune Inc | Drug with the option of oral, intra-intestinal, or inhaled dosing for suppression of autoimmune response associated with type I diabetes |
| EP0553291B1 (fr) * | 1990-10-15 | 2006-03-08 | Autoimmune, Inc. | Traitement de maladies auto-immunes par administration orale d'auto-antigenes |
| US6613332B1 (en) | 1991-06-21 | 2003-09-02 | The University Of Cincinnati | Oral administration of therapeutic proteins |
| EP0590060B1 (fr) * | 1991-06-21 | 1997-09-17 | University Of Cincinnati | Proteines therapeutiques administrables par voie orale et leur procede de production |
| DE69332518T2 (de) * | 1992-02-28 | 2003-09-04 | Autoimmune Inc | Unterdrückung von autoimmunkrankheiten durch antigene in wartestellung |
| US5824315A (en) * | 1993-10-25 | 1998-10-20 | Anergen, Inc. | Binding affinity of antigenic peptides for MHC molecules |
| US5879656A (en) * | 1993-10-26 | 1999-03-09 | Thomas Jefferson University | Methods of treating metastatic colorectal cancer with ST receptor binding compounds |
| US5962220A (en) * | 1993-10-26 | 1999-10-05 | Thomas Jefferson University | Compositions that specifically bind to colorectal cells and methods of using the same |
| US7097839B1 (en) * | 1993-10-26 | 2006-08-29 | Thomas Jefferson University | ST receptor binding compounds and methods of using the same |
| US5645851A (en) * | 1994-02-28 | 1997-07-08 | Moore; Eugene R. | Product for alleviating the symptons of arthritis in mammals |
| US5529786A (en) * | 1994-02-28 | 1996-06-25 | Moore; Eugene R. | Process and product for treatment of rheumatoid arthritis |
| GB9403857D0 (en) * | 1994-03-01 | 1994-04-20 | Scotia Holdings Plc | Fatty acid derivatives |
| WO1996020950A2 (fr) * | 1995-01-06 | 1996-07-11 | Immulogic Pharmaceutical Corporation | Compositions et therapies pour le traitement de la polyarthrite rhumatoide |
| EP0805686A1 (fr) * | 1995-01-10 | 1997-11-12 | Fibrogen, Inc. | Methodes et formulations a base de collagene pour le traitement de maladies d'origine immunologique |
| US5925736A (en) * | 1995-01-10 | 1999-07-20 | Fibrogen, Inc. | Collagen-based methods and formulations for the treatment of arthritis |
| EP0871478A1 (fr) * | 1995-06-07 | 1998-10-21 | Autoimmune, Inc. | Tolerance induite par voie orale pour le traitement de maladies de la peau impliquant une inflammation induite par les lymphocytes t |
| CA2224709C (fr) * | 1995-06-13 | 2009-05-12 | Nippon Meat Packers, Inc. | Medicament a administration par voie orale, contre la polyarthrite rhumatoide et aliment actif |
| US5856446A (en) * | 1995-07-07 | 1999-01-05 | Autoimmune Inc. | Method of treating rheumatoid arthritis with low dose type II collagen |
| US20020182730A1 (en) * | 1995-07-26 | 2002-12-05 | Micheal L. Gruenberg | Autologous immune cell therapy: cell compositions, methods and applications to treatment of human disease |
| JP3935938B2 (ja) * | 1996-01-05 | 2007-06-27 | オートイミューン インク | ▲ｉｉ▼型コラーゲンの調製法 |
| WO1997044059A2 (fr) * | 1996-05-23 | 1997-11-27 | Shriner's Hospitals For Children | Collagene de type ii de cartilage utilise en tant que facteur angiogenique |
| US5962025A (en) * | 1996-07-16 | 1999-10-05 | The University Of Tennessee Research Corporation | Method for treatment of systemic sclerosis and related fibrotic diseases |
| CA2252790A1 (fr) * | 1997-02-28 | 1998-09-03 | Enzo Therapeutics, Inc. | Nouveaux procedes de retro-regulation immunitaire selective (sidr) |
| US7097845B2 (en) | 1997-04-23 | 2006-08-29 | Jacob Sten Petersen | Combinations of antigen and mucosal binding component for inducing specific immunological tolerance |
| US5849323A (en) * | 1997-06-12 | 1998-12-15 | A. Glenn Braswell | Collagen mimetic and method of treating rheumatoid arthritis using same |
| US5849336A (en) * | 1997-07-02 | 1998-12-15 | Abbott Laboratories | Method using sturgeon notochord for alleviating the symptoms of arthritis |
| US6120995A (en) * | 1997-08-07 | 2000-09-19 | Thomas Jefferson University | Compositions that specifically bind to colorectal cancer cells and methods of using the same |
| US7135333B1 (en) | 1997-08-07 | 2006-11-14 | Thomas Jefferson University | Compositions that specifically bind to colorectal cancer cells and methods of using the same |
| US6025327A (en) * | 1997-08-08 | 2000-02-15 | Biocell Technology, Llc | Hydrolyzed collagen type II and use thereof |
| IL136230A0 (en) * | 1997-11-28 | 2001-05-20 | Roche Diagnostics Gmbh | An active hedgehog-protein-mutant, a process for its preparation and its use for pharmaceutical purposes |
| US6897297B1 (en) | 1997-12-03 | 2005-05-24 | Curis, Inc. | Hydrophobically-modified protein compositions and methods |
| DE69830192T2 (de) | 1997-12-03 | 2006-01-12 | Biogen Idec Ma Inc., Cambridge | Hydrophobisch-modifizierte Hedgehog Protein Zusammensetzungen und Verfahren |
| US5935577A (en) * | 1998-01-23 | 1999-08-10 | Autoimmune Inc. | Treatment of autoimmune disease using tolerization in combination with methotrexate |
| IL126447A (en) * | 1998-10-04 | 2004-09-27 | Vascular Biogenics Ltd | An immune preparation that confers tolerance in oral administration and its use in the prevention and / or treatment of atherosclerosis |
| US20050197283A1 (en) * | 1998-10-04 | 2005-09-08 | Vascular Biogenics Ltd. | Compositions containing beta 2-glycoprotein I for the prevention and/or treatment of vascular disease |
| US6162787A (en) * | 1999-04-02 | 2000-12-19 | Immudyne, Inc. | Methods for treating arthritis using collagen type II, glucosamine chondroitin sulfate, and compositions |
| SE9902155L (sv) * | 1999-06-09 | 2000-12-10 | Bjoern Rydevik | Serum antibodies |
| US6524609B1 (en) * | 1999-08-18 | 2003-02-25 | Nutri-Vet, Llc | Treating arthritis in animals with dietary supplements |
| US6372794B1 (en) | 1999-08-26 | 2002-04-16 | Marcel E. Nimni | Method for alleviating arthritis in mammals |
| CA2404431C (fr) | 2000-03-27 | 2011-06-07 | Thomas Jefferson University | Guanylyl cyclase c servant a deceler les cancers de l'estomac et de l'oesophage |
| US7897575B2 (en) | 2000-05-24 | 2011-03-01 | The United States Of America As Represented By The Department Of Health And Human Services | Treatment and prevention of vascular dementia |
| EP1286686B1 (fr) | 2000-05-24 | 2007-07-25 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by THE SECRETARY of the DEPARTMENT OF HEALTH AND HUMAN SERVICES | E-selectin pour le traitement ou la prevention des accidents vasculaires cerebraux |
| US6894029B1 (en) | 2000-11-13 | 2005-05-17 | Auburn University | Use of jellyfish collagen (type II) in the treatment of rheumatoid arthritis |
| US6721142B1 (en) * | 2000-12-21 | 2004-04-13 | Western Digital (Fremont) Inc. | Non-corrosive GMR slider for proximity recording |
| US6838440B2 (en) * | 2001-01-24 | 2005-01-04 | Collagen Nutraceuticals, Inc. | Kolla2-desiccated avian sternal cartilage powder |
| FR2821947B1 (fr) * | 2001-03-12 | 2003-05-16 | Canon Kk | Procede et dispositif de validation de parametres definissant une image |
| US20030134341A1 (en) * | 2001-09-19 | 2003-07-17 | Medcell Biologics, Llc. | Th1 cell adoptive immunotherapy |
| US20030134415A1 (en) * | 2001-09-19 | 2003-07-17 | Gruenberg Micheal L. | Th1 cell adoptive immunotherapy |
| US6780841B2 (en) | 2001-11-13 | 2004-08-24 | Biocell Technology, Llc | Hyaluronic acid and chondroitin sulfate based hydrolyzed collagen type II and method of making same |
| US20050154046A1 (en) * | 2004-01-12 | 2005-07-14 | Longgui Wang | Methods of treating an inflammatory-related disease |
| US8563525B2 (en) | 2004-01-12 | 2013-10-22 | Natrogen Therapeutics International, Inc. | Methods of treating an inflammatory-related disease |
| US7582670B2 (en) * | 2001-12-13 | 2009-09-01 | Natrogen Therapeutics, Inc. | Methods of treating an inflammatory-related disease |
| JP2005519914A (ja) | 2002-01-23 | 2005-07-07 | インスティチュート オブ ニュートラシューティカル リサーチ ピーティーワイ リミテッド | 結合組織の治療、防御および回復のためのニュートラシューティカルズ（ｎｕｔｒａｃｅｕｔｉｃａｌｓ） |
| US20030175272A1 (en) * | 2002-03-07 | 2003-09-18 | Medcell Biologics, Inc. | Re-activated T-cells for adoptive immunotherapy |
| EP1599165A4 (fr) * | 2003-02-10 | 2010-09-08 | Univ Jefferson | Utilisation de ligands gcc |
| GB0307989D0 (en) | 2003-04-07 | 2003-05-14 | Mcewen Lab Ltd | Therapeutic composition |
| AU2003903037A0 (en) * | 2003-06-17 | 2003-07-03 | Institute Of Nutraceutical Research | Connective tissue derived polypeptides |
| JP2007522109A (ja) * | 2004-01-15 | 2007-08-09 | ノボ ノルディスク アクティーゼルスカブ | 自己免疫疾患の治療およびｉｌ−２１での同種異系移植片拒絶反応 |
| US20090068207A1 (en) * | 2005-04-15 | 2009-03-12 | Vascular Biogenics Ltd. | Compositions Containing Beta 2-Glycoprotein I-Derived Peptides for the Prevention and/or Treatment of Vascular Disease |
| US9549959B2 (en) * | 2006-09-15 | 2017-01-24 | I Did It, Inc. | Animal chew toy containing solid food |
| US8703174B2 (en) * | 2006-09-15 | 2014-04-22 | I Did It Inc | Joint preserving nutritional vitamin, mineral and herbal pet supplement |
| US7851436B2 (en) * | 2007-04-05 | 2010-12-14 | Washington University | Inhibition of migration and induction of cell death by the type II collagen amino propeptides |
| WO2009038771A2 (fr) * | 2007-09-19 | 2009-03-26 | Massachusetts Institute Of Technology | Tolpérisone et médicaments de type tolpérisone pour le traitement de cancers associés au k-ras |
| CN101426268B (zh) * | 2007-11-02 | 2010-08-25 | 大唐移动通信设备有限公司 | 导频资源分配方法、系统和设备 |
| US9023416B2 (en) | 2012-01-27 | 2015-05-05 | Cartilast II LLC | Preservation of the biological activity of undenatured type II collagen |
| EP2900808B1 (fr) | 2012-09-28 | 2019-04-03 | Scripps Health | Procédés de différenciation de cellules souches en chondrocytes |
| WO2014070796A1 (fr) * | 2012-10-29 | 2014-05-08 | Scripps Health | Méthodes de greffe des chondrocytes |
| EP2912166B1 (fr) | 2012-10-29 | 2019-05-01 | Scripps Health | Procédés de production de cellules souches pluripotentes à partir de chondrocytes |
| US8652530B1 (en) | 2013-01-23 | 2014-02-18 | Cartilast Corp. | Preservation of the biological activity of undenatured type II collagen |
| MY180106A (en) | 2013-10-24 | 2020-11-23 | Interhealth Nutraceuticals Incorporated | Method of reducing exercise-induced joint pain in non-arthritic mammals |
| US10226513B2 (en) | 2015-01-09 | 2019-03-12 | Mark Terrell Smith | Method and composition to prevent or improve symptoms of musculoskeletal distress degeneration |
| CA3099905A1 (fr) | 2017-05-11 | 2018-11-15 | Avicenna Nutracetical, Llc | Procedes de production de collagene |
| DE102021202830A1 (de) | 2021-03-23 | 2022-09-29 | Gelita Ag | Rekombinantes Typ II-Kollagen zur therapeutischen Verwendung |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1302880C (fr) * | 1986-07-25 | 1992-06-09 | Peter Koepff | Agents pour le traitement de l'arthrose |
-
1992
- 1992-09-25 US US07/951,565 patent/US5399347A/en not_active Expired - Lifetime
-
1993
- 1993-09-20 IL IL10705093A patent/IL107050A/en not_active IP Right Cessation
- 1993-09-24 AU AU54399/94A patent/AU5439994A/en not_active Abandoned
- 1993-09-24 WO PCT/US1993/009113 patent/WO1994007520A1/fr not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU5439994A (en) | 1994-04-26 |
| IL107050A0 (en) | 1993-12-28 |
| WO1994007520A1 (fr) | 1994-04-14 |
| US5399347A (en) | 1995-03-21 |
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| EXP | Patent expired |