IL105882A0 - Heterocyclic derivatives - Google Patents

Heterocyclic derivatives

Info

Publication number
IL105882A0
IL105882A0 IL105882A IL10588293A IL105882A0 IL 105882 A0 IL105882 A0 IL 105882A0 IL 105882 A IL105882 A IL 105882A IL 10588293 A IL10588293 A IL 10588293A IL 105882 A0 IL105882 A0 IL 105882A0
Authority
IL
Israel
Prior art keywords
pct
derivatives
treating
date
alkylcarbamoyl
Prior art date
Application number
IL105882A
Other languages
English (en)
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Publication of IL105882A0 publication Critical patent/IL105882A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
IL105882A 1992-06-04 1993-06-02 Heterocyclic derivatives IL105882A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929211796A GB9211796D0 (en) 1992-06-04 1992-06-04 Heterocyclic derivatives

Publications (1)

Publication Number Publication Date
IL105882A0 true IL105882A0 (en) 1993-10-20

Family

ID=10716501

Family Applications (1)

Application Number Title Priority Date Filing Date
IL105882A IL105882A0 (en) 1992-06-04 1993-06-02 Heterocyclic derivatives

Country Status (14)

Country Link
US (1) US5554613A (xx)
EP (1) EP0598093B1 (xx)
JP (1) JPH06509590A (xx)
AT (1) ATE160348T1 (xx)
AU (1) AU670295B2 (xx)
CA (1) CA2097671A1 (xx)
DE (1) DE69315307T2 (xx)
FI (1) FI940503A (xx)
GB (2) GB9211796D0 (xx)
IL (1) IL105882A0 (xx)
NZ (1) NZ253230A (xx)
TW (1) TW276252B (xx)
WO (1) WO1993024486A1 (xx)
ZA (1) ZA933644B (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9122988D0 (en) * 1991-10-30 1991-12-18 Ici Plc Heterocyclic compounds
GB9218334D0 (en) * 1992-08-28 1992-10-14 Ici Plc Heterocyclic compounds
DE69330069D1 (en) * 1992-12-21 2001-05-03 Syngenta Ltd Chinuclidin derivate als squalen synthase inhibitoren
US5556990A (en) * 1994-12-16 1996-09-17 Rhone-Poulenc Rorer Pharmaceuticals Inc. Polyarylcarbamoylaza- and -carbamoylalkanedioic acids
US20040186071A1 (en) 1998-04-13 2004-09-23 Bennett C. Frank Antisense modulation of CD40 expression
EP1851206B1 (en) * 2005-02-22 2012-08-15 Teva Pharmaceutical Industries, Ltd. Rosuvastatin and salts thereof free of rosuvastatin alkylether and a process for the preparation thereof
US8916531B2 (en) 2007-11-20 2014-12-23 Isis Pharmaceuticals, Inc. Modulation of CD40 expression

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3405134A (en) * 1965-08-17 1968-10-08 Colgate Palmolive Co Quinuclidyl esters of aromatic acids
NL6715600A (xx) * 1966-12-02 1968-06-04
US3534053A (en) * 1967-05-24 1970-10-13 American Home Prod Quinuclidine derivatives
US3655675A (en) * 1968-09-09 1972-04-11 Sterling Drug Inc N-(n-heteryl)-acylanilides
US3763168A (en) * 1968-09-09 1973-10-02 Sterling Drug Inc N-(3-quinuclidinyl) acylanilides
US3725410A (en) * 1970-07-15 1973-04-03 American Home Prod 3-aminomethyl-3-quinuclidinols
US3679690A (en) * 1971-03-18 1972-07-25 Sterling Drug Inc Certain n-(pyridyl) propionanilides
FR2183565B1 (xx) * 1972-05-10 1975-12-26 Cerm Cent Europ Rech Mauvernay
CA1014958A (en) * 1973-10-05 1977-08-02 Jacques Moleyre .alpha.-QUINUCLIDYLMETHYL PHENYL KETONES
SU495310A1 (ru) * 1974-03-05 1975-12-15 Всесоюзный Научно-Исследовательский Химико-Фармацевтический Институт Им.С.Орджоникидзе Хинуклидил-3-диарал(гетерил) карбинолы, про вл ющие антигистаминную, антисеротониновую и антиаллергическую активность и способ их получени
US4038402A (en) * 1974-03-05 1977-07-26 Mikhail Emmanuilovich Kaminka Method of effecting antihistaminic, antiserotonin and antiallergic actions
FR2414044A1 (fr) * 1978-01-10 1979-08-03 Pharmindustrie Nouveaux derives d'aza-1 bicyclo(2,2,2) octane, utilisables comme medicaments
US4599344A (en) * 1984-10-31 1986-07-08 Schering A.G. Quinuclidines and quinuclidinium salts as antiarrhythmic agents
CH667657A5 (de) * 1985-01-07 1988-10-31 Sandoz Ag Carbocyclische und heterocyclische carbonylmethylen- und methylpiperidine und -pyrrolidine.
NZ225999A (en) * 1987-09-10 1992-04-28 Merck Sharp & Dohme Azacyclic- or azabicyclic-substituted thiadiazole derivatives and pharmaceutical compositions
IE63906B1 (en) * 1987-11-13 1995-06-14 Novo Nordisk As Azabicyclic compounds and their preparation and use
EP0322182A3 (en) * 1987-12-22 1992-01-02 Beecham Group Plc Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them
DK730588A (da) * 1988-02-03 1989-08-04 Asta Pharma Ag Anvendelse af pyridin-2-ethere eller pyridin-2-thioethere med en nitrogenholdig cycloalifatisk ring som antidepressivt laegemiddel
NZ227841A (en) * 1988-02-12 1991-08-27 Merck Sharp & Dohme Heterocyclic compounds with at least two non-condensed five membered rings and pharmaceutical compositions
US5242914A (en) * 1988-04-01 1993-09-07 Sankyo Company, Limited 2-(heterocyclylthio) carbapenem derivatives, their preparation and their use as antibiotics
ES2067534T3 (es) * 1988-04-01 1995-04-01 Sankyo Co Derivados de 2-(heterocicliltio)carbapenemo, su preparacion y su aplicacion como antibioticos.
US5286864A (en) * 1988-11-22 1994-02-15 Boehringer Ingelheim Kg Quinuclidines, their use as medicaments and processes for their preparation
DE8817121U1 (de) * 1988-11-22 1993-02-04 Boehringer Ingelheim Kg, 55218 Ingelheim Neue Quinuclidine
GB8918061D0 (en) * 1989-08-08 1989-09-20 Merck Sharp & Dohme Therapeutic agents
DE4116582A1 (de) * 1990-05-19 1991-11-21 Boehringer Ingelheim Kg Bicyclische 1-aza-cycloalkane
YU84791A (xx) * 1990-05-19 1994-06-10 Boehringer Ingelheim Kg. Biciklični 1-aza-cikloalkalni
ZA92278B (en) * 1991-02-01 1992-10-28 Akzo Nv 3-quinuclidine derivatives
US5385912A (en) * 1991-03-08 1995-01-31 Rhone-Poulenc Rorer Pharmaceuticals Inc. Multicyclic tertiary amine polyaromatic squalene synthase inhibitors
WO1992015579A1 (en) * 1991-03-08 1992-09-17 Rhone-Poulenc Rorer International (Holdings) Inc. Multicyclic tertiary amine polyaromatic squalene synthetase inhibitors
US5135935A (en) * 1991-05-17 1992-08-04 Merck & Co., Inc. Squalene synthetase inhibitors
GB9122988D0 (en) * 1991-10-30 1991-12-18 Ici Plc Heterocyclic compounds
GB9201749D0 (en) * 1992-01-28 1992-03-11 Smithkline Beecham Plc Medicaments
GB9202443D0 (en) * 1992-02-05 1992-03-18 Fujisawa Pharmaceutical Co A novel substituted-acetamide compound and a process for the preparation thereof

Also Published As

Publication number Publication date
FI940503A0 (fi) 1994-02-03
US5554613A (en) 1996-09-10
GB9211796D0 (en) 1992-07-15
JPH06509590A (ja) 1994-10-27
AU4339893A (en) 1993-12-30
EP0598093A1 (en) 1994-05-25
ATE160348T1 (de) 1997-12-15
TW276252B (xx) 1996-05-21
NZ253230A (en) 1996-06-25
WO1993024486A1 (en) 1993-12-09
DE69315307T2 (de) 1998-03-12
FI940503A (fi) 1994-02-03
ZA933644B (en) 1993-12-06
GB9310418D0 (en) 1993-07-07
DE69315307D1 (de) 1998-01-02
EP0598093B1 (en) 1997-11-19
AU670295B2 (en) 1996-07-11
CA2097671A1 (en) 1993-12-05

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