IL104086A - Translational activating oligonucleotide sequence useful for the high level expression of polypeptides and a method for producing such polypeptides - Google Patents

Translational activating oligonucleotide sequence useful for the high level expression of polypeptides and a method for producing such polypeptides

Info

Publication number
IL104086A
IL104086A IL104086A IL10408692A IL104086A IL 104086 A IL104086 A IL 104086A IL 104086 A IL104086 A IL 104086A IL 10408692 A IL10408692 A IL 10408692A IL 104086 A IL104086 A IL 104086A
Authority
IL
Israel
Prior art keywords
plasmid
sequence
dna
fragment
expression vector
Prior art date
Application number
IL104086A
Other languages
English (en)
Other versions
IL104086A0 (en
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL104086A0 publication Critical patent/IL104086A0/xx
Publication of IL104086A publication Critical patent/IL104086A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/73—Expression systems using phage (lambda) regulatory sequences

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Programmable Controllers (AREA)
  • Peptides Or Proteins (AREA)
IL104086A 1991-12-18 1992-12-14 Translational activating oligonucleotide sequence useful for the high level expression of polypeptides and a method for producing such polypeptides IL104086A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81104591A 1991-12-18 1991-12-18

Publications (2)

Publication Number Publication Date
IL104086A0 IL104086A0 (en) 1993-05-13
IL104086A true IL104086A (en) 1998-03-10

Family

ID=25205390

Family Applications (1)

Application Number Title Priority Date Filing Date
IL104086A IL104086A (en) 1991-12-18 1992-12-14 Translational activating oligonucleotide sequence useful for the high level expression of polypeptides and a method for producing such polypeptides

Country Status (12)

Country Link
EP (1) EP0547873B1 (fr)
JP (1) JPH05276950A (fr)
AT (1) ATE157122T1 (fr)
AU (1) AU663139B2 (fr)
CA (1) CA2085447A1 (fr)
DE (1) DE69221708T2 (fr)
DK (1) DK0547873T3 (fr)
ES (1) ES2104856T3 (fr)
GR (1) GR3024762T3 (fr)
HU (1) HU218269B (fr)
IL (1) IL104086A (fr)
MX (1) MX9207265A (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002232758A1 (en) 2000-12-26 2002-07-08 Monsanto Technology Llc Recombinant dna vectors for expression of somatotropins

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5126249A (en) * 1989-05-09 1992-06-30 Eli Lilly And Company Enzymatic removal of a protein amino-terminal sequence
IL99100A0 (en) * 1990-08-13 1992-07-15 Lilly Co Eli Improved bacteriophage lambda pl promoters

Also Published As

Publication number Publication date
HU9203981D0 (en) 1993-04-28
GR3024762T3 (en) 1997-12-31
MX9207265A (es) 1993-07-01
EP0547873B1 (fr) 1997-08-20
DE69221708T2 (de) 1998-01-22
JPH05276950A (ja) 1993-10-26
HUT65816A (en) 1994-07-28
ATE157122T1 (de) 1997-09-15
DE69221708D1 (de) 1997-09-25
EP0547873A3 (fr) 1994-08-31
DK0547873T3 (da) 1997-09-15
ES2104856T3 (es) 1997-10-16
CA2085447A1 (fr) 1993-06-19
AU663139B2 (en) 1995-09-28
IL104086A0 (en) 1993-05-13
EP0547873A2 (fr) 1993-06-23
AU3019592A (en) 1993-06-24
HU218269B (hu) 2000-06-28

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees