IL100549A - Anti-herpes pharmaceuticals and cosmetics containing a combination of an antiviral nucleoside analogue and a derivative of a reductase inhibitory ribonucleotide peptide - Google Patents

Anti-herpes pharmaceuticals and cosmetics containing a combination of an antiviral nucleoside analogue and a derivative of a reductase inhibitory ribonucleotide peptide

Info

Publication number
IL100549A
IL100549A IL10054991A IL10054991A IL100549A IL 100549 A IL100549 A IL 100549A IL 10054991 A IL10054991 A IL 10054991A IL 10054991 A IL10054991 A IL 10054991A IL 100549 A IL100549 A IL 100549A
Authority
IL
Israel
Prior art keywords
asp
tbg
val
cypn
pyrrolidino
Prior art date
Application number
IL10054991A
Other languages
English (en)
Hebrew (he)
Other versions
IL100549A0 (en
Inventor
Robert Deziel
Yvan Guindon
Original Assignee
Bio Mega Boehringer Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio Mega Boehringer Ingelheim filed Critical Bio Mega Boehringer Ingelheim
Publication of IL100549A0 publication Critical patent/IL100549A0/xx
Publication of IL100549A publication Critical patent/IL100549A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/005—Enzyme inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A61K8/606—Nucleosides; Nucleotides; Nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782—Enzyme inhibitors; Enzyme antagonists
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16622—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Birds (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Dental Preparations (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IL10054991A 1990-12-31 1991-12-30 Anti-herpes pharmaceuticals and cosmetics containing a combination of an antiviral nucleoside analogue and a derivative of a reductase inhibitory ribonucleotide peptide IL100549A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA002033448A CA2033448C (en) 1990-12-31 1990-12-31 Antiherpes compositions and method of use

Publications (2)

Publication Number Publication Date
IL100549A0 IL100549A0 (en) 1992-09-06
IL100549A true IL100549A (en) 1995-11-27

Family

ID=4146737

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10054991A IL100549A (en) 1990-12-31 1991-12-30 Anti-herpes pharmaceuticals and cosmetics containing a combination of an antiviral nucleoside analogue and a derivative of a reductase inhibitory ribonucleotide peptide

Country Status (9)

Country Link
US (1) US5552384A (ja)
EP (1) EP0493770B1 (ja)
JP (1) JP3209552B2 (ja)
AT (1) ATE156362T1 (ja)
AU (1) AU648855B2 (ja)
CA (1) CA2033448C (ja)
DE (1) DE69127184T2 (ja)
IL (1) IL100549A (ja)
NZ (1) NZ241121A (ja)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5846941A (en) * 1992-03-12 1998-12-08 Boehringer Ingelheim (Canada) Ltd. Isosteric antiherpes peptide derivatives II
ES2152269T3 (es) * 1993-03-03 2001-02-01 Boehringer Ingelheim Ca Ltd Inhibidores de ribonucleotido-reductasa de herpesvirus.
CA2095408A1 (en) * 1993-05-03 1994-11-04 James Gus Chafouleas Method of combating acyclovir-resistant herpes simplex viral infections
US5459063A (en) * 1993-10-14 1995-10-17 The University Of Pennsylvania Plasmodium falciparum ribonucleotide reductase DNA
US6194143B1 (en) 1996-12-27 2001-02-27 Boehringer Ingelheim (Canada) Ltd. Substrates for human cytomegalovirus protease
JP4110347B2 (ja) * 1999-11-05 2008-07-02 大鵬薬品工業株式会社 抗ｈｉｖ剤
WO2011035120A2 (en) * 2009-09-17 2011-03-24 Gk Ventures, L.L.C. Therapeutic composition to treat lesions caused by herpes simplex virus
US8853223B2 (en) 2010-09-17 2014-10-07 G2L Touch, Inc. Therapeutic composition to treat lesions caused by herpes simplex virus
JP2014141475A (ja) * 2012-12-27 2014-08-07 Daiichi Sankyo Co Ltd 新規美白剤
CN112996789A (zh) 2018-09-12 2021-06-18 诺华股份有限公司 抗病毒吡啶并吡嗪二酮化合物
KR20220070005A (ko) 2019-09-26 2022-05-27 노파르티스 아게 항바이러스성 피라졸로피리디논 화합물

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4795740A (en) * 1986-05-20 1989-01-03 Cohen Eric A Antiviral peptides and means for treating herpes infections
GB8815241D0 (en) * 1988-06-27 1988-08-03 Wellcome Found Antiviral combinations & compounds therefor

Also Published As

Publication number Publication date
EP0493770B1 (en) 1997-08-06
JPH04275229A (ja) 1992-09-30
ATE156362T1 (de) 1997-08-15
CA2033448C (en) 1996-11-26
EP0493770A3 (en) 1993-03-17
JP3209552B2 (ja) 2001-09-17
DE69127184D1 (de) 1997-09-11
AU648855B2 (en) 1994-05-05
US5552384A (en) 1996-09-03
EP0493770A2 (en) 1992-07-08
IL100549A0 (en) 1992-09-06
NZ241121A (en) 1994-06-27
DE69127184T2 (de) 1997-12-18
AU9009391A (en) 1992-07-02
CA2033448A1 (en) 1992-07-01

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Legal Events

Date Code Title Description
FF Patent granted
HP Change in proprietorship
KB Patent renewed
RH Patent void
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees