IES20180261A2 - Drug intermediates 3,4,5-trimethoxybenzaldehyde synthesis method - Google Patents

Drug intermediates 3,4,5-trimethoxybenzaldehyde synthesis method

Info

Publication number
IES20180261A2
IES20180261A2 IES20180261A IES20180261A2 IE S20180261 A2 IES20180261 A2 IE S20180261A2 IE S20180261 A IES20180261 A IE S20180261A IE S20180261 A2 IES20180261 A2 IE S20180261A2
Authority
IE
Ireland
Prior art keywords
solution
trimethoxybenzaldehyde
added
temperature
synthesis method
Prior art date
Application number
Inventor
Liao Ruer
Original Assignee
Chengdu Ka Di Fu Tech Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chengdu Ka Di Fu Tech Co Ltd filed Critical Chengdu Ka Di Fu Tech Co Ltd
Publication of IES20180261A2 publication Critical patent/IES20180261A2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78—Separation; Purification; Stabilisation; Use of additives
    • C07C45/81—Separation; Purification; Stabilisation; Use of additives by change in the physical state, e.g. crystallisation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The present invention discloses drug intermediates 3,4,5-trimethoxybenzaldehyde synthesis method, comprises the following steps: the reaction vessel is charged with 2,6-dibromo-3,4,5-trimethoxy-benzyl alcohol and hexane, controls the temperature of the solution, the aqueous solution, potassium peroxodisulfate are added, continues to react; then sodium nitrate solution and chlorine iridium acid powder are added, raises the temperature, continues to react, sodium chloride solution is added, reduces the temperature, standing, after the solution layers, washed with biphenyl solution, recrystallized in the o-dinitrobenzene solution, dehydrated with dehydration, gets the finished product 3,4,5-trimethoxybenzaldehyde. <Figure 1>
IES20180261 2017-09-07 2018-08-23 Drug intermediates 3,4,5-trimethoxybenzaldehyde synthesis method IES20180261A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710797628.2A CN108238882A (en) 2017-09-07 2017-09-07 The synthetic method of pharmaceutical intermediate 3,4,5-Trimethoxybenzaldehyde

Publications (1)

Publication Number Publication Date
IES20180261A2 true IES20180261A2 (en) 2019-11-13

Family

ID=60117386

Family Applications (1)

Application Number Title Priority Date Filing Date
IES20180261 IES20180261A2 (en) 2017-09-07 2018-08-23 Drug intermediates 3,4,5-trimethoxybenzaldehyde synthesis method

Country Status (4)

Country Link
CN (1) CN108238882A (en)
AU (1) AU2018101124A4 (en)
GB (1) GB201714446D0 (en)
IE (1) IES20180261A2 (en)

Also Published As

Publication number Publication date
GB201714446D0 (en) 2017-10-25
CN108238882A (en) 2018-07-03
AU2018101124A4 (en) 2018-09-06

Similar Documents

Publication Publication Date Title
EA201491189A1 (en) METHOD OF OBTAINING LEVULINIC ACID
IES20180261A2 (en) Drug intermediates 3,4,5-trimethoxybenzaldehyde synthesis method
IE20180281U1 (en) Benzoyl peroxide organic intermediates synthesis method
IE20180280U1 (en) Methylchloroperoxybenzoic acid drug intermediates synthesis method
IES20180251U1 (en) Nicotinamide-n-oxide drug intermediates synthesis method
MX2020006641A (en) Process for the preparation of pyrimidinyl-4-aminopyrazole compounds.
IES20180266A2 (en) 2-furanacrylic acid drug intermediates synthesis method
IE20180288U1 (en) P-methoxphenylacetic acid drug intermediates synthesis method
IE20180289U1 (en) 2-nitro-4-aminobenzaldehyde drug intermediates synthesis method
IES20180260U1 (en) Drug intermediates 1-methyl-2-quinolinone synthesis method
IES20180254U1 (en) L-dopa drug intermediates synthesis method
IE20180284U1 (en) 2,3-dihydroxy-succinic acid drug intermediates synthesis method
IES20180294A2 (en) 2-(4-isobutylphenyl) propionic acid drug intermediates synthesis method
IES20180263A2 (en) Drug intermediates 3-methoxy-2-thiophenecarboxaldehyde synthesis method
IES20180291A2 (en) Acetone dicarboxylic acid drug intermediates synthesis method
IE20180283U1 (en) O-toluene formamide organic intermediates synthesis method
IES20180203A2 (en) Chlormadinone drug intermediates o-tetrachlorobenzoquinone synthesis method
IES20180195A2 (en) Pharmaceutical hormone intermediates 11-ketone-16α, 17α-epoxy progesterone synthesis method
IES20180275U1 (en) Drug intermediates 3-oxoheptanone ethylene glycol synthesis method
IES20180113A2 (en) Drug intermediates p-benzoylbenzoic acid synthesis method
IE20180282U1 (en) Dodecanoyl peroxide organic intermediates synthesis method
IES20180202A2 (en) Trienegolinone intermediates dichlorobenzoquinone synthesis method
IE20180292U1 (en) 7-(3,5,6-trimethyl-1,4-benzoquinon-2-yl)-7-phenyl heptanoic acid synthesis method
IES20180242U1 (en) Broad spectrum antimicrobial agents thiamphenicol synthesis method
IES20180289A2 (en) 2-nitro-4-aminobenzaldehyde drug intermediates synthesis method

Legal Events

Date Code Title Description
FJ9A Application deemed to be withdrawn section 31(3)