IE20180288U1 - P-methoxphenylacetic acid drug intermediates synthesis method - Google Patents

P-methoxphenylacetic acid drug intermediates synthesis method

Info

Publication number
IE20180288U1
IE20180288U1 IE20180288U IE20180288U IE20180288U1 IE 20180288 U1 IE20180288 U1 IE 20180288U1 IE 20180288 U IE20180288 U IE 20180288U IE 20180288 U IE20180288 U IE 20180288U IE 20180288 U1 IE20180288 U1 IE 20180288U1
Authority
IE
Ireland
Prior art keywords
solution
added
temperature
synthesis method
acid drug
Prior art date
Application number
IE20180288U
Inventor
Yan Yida
Original Assignee
Chengdu Ao Ka Te Tech Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chengdu Ao Ka Te Tech Co Ltd filed Critical Chengdu Ao Ka Te Tech Co Ltd
Publication of IE20180288U1 publication Critical patent/IE20180288U1/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/377—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The present invention discloses p-methoxyphenylacetic acid drug intermediates synthesis method, comprises the following steps: 4-methoxy-6-methyl-benzaldehyde and sodium nitrate solution is added to the reaction vessel, controls the temperature of the solution, controls the stirring speed, ethylene glycol solution and aluminum isopropoxide is added, continues to react; then cobalt chloride powder is added, raises the temperature, continues to react, reduces the temperature, oxalic acid solution is added to adjust the pH, washed with potassium sulfate solution, washed with tri-pentylbenzene solution, recrystallized in triethylene glycol solution, dehydrated with dehydration, gets the finished product p-methoxyphenylacetic acid. <Figure 1>
IE20180288U 2017-09-17 2018-08-23 P-methoxphenylacetic acid drug intermediates synthesis method IE20180288U1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710836738.5A CN108238896A (en) 2017-09-17 2017-09-17 The synthetic method of homoanisic acid pharmaceutical intermediate

Publications (1)

Publication Number Publication Date
IE20180288U1 true IE20180288U1 (en) 2020-10-14

Family

ID=62700432

Family Applications (1)

Application Number Title Priority Date Filing Date
IE20180288U IE20180288U1 (en) 2017-09-17 2018-08-23 P-methoxphenylacetic acid drug intermediates synthesis method

Country Status (3)

Country Link
CN (1) CN108238896A (en)
AU (1) AU2018101139A4 (en)
IE (1) IE20180288U1 (en)

Also Published As

Publication number Publication date
AU2018101139A4 (en) 2018-09-13
CN108238896A (en) 2018-07-03

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