IE820703L - Lyophilized preparation of a penicillin derivative - Google Patents

Lyophilized preparation of a penicillin derivative

Info

Publication number
IE820703L
IE820703L IE820703A IE70382A IE820703L IE 820703 L IE820703 L IE 820703L IE 820703 A IE820703 A IE 820703A IE 70382 A IE70382 A IE 70382A IE 820703 L IE820703 L IE 820703L
Authority
IE
Ireland
Prior art keywords
penicillin derivative
lyophilized
lyophilized preparation
concentration
product
Prior art date
Application number
IE820703A
Other versions
IE52936B1 (en
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22935482&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IE820703(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of IE820703L publication Critical patent/IE820703L/en
Publication of IE52936B1 publication Critical patent/IE52936B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Abstract

Preparation of a pharmaceutical parenteral dosage unit of a lyophilized penicillin derivative in which the penicillin derivative is dissolved in water to a concentration of 100-135 mg/ml, as compared to the standard concentration of 200 mg/ml. The solution is then filled into a container and lyophilized by known techniques. The product is a light, fluffy lyophilized product which upon reconstitution will go into solution rapidly and completely even at the high concentration of 400 mg/ml. [GB2095551A]
IE703/82A 1981-03-26 1982-03-25 Composition of matter comprising a lyophilized preparation of a penicillin derivative IE52936B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24758681A 1981-03-26 1981-03-26

Publications (2)

Publication Number Publication Date
IE820703L true IE820703L (en) 1982-09-26
IE52936B1 IE52936B1 (en) 1988-04-13

Family

ID=22935482

Family Applications (1)

Application Number Title Priority Date Filing Date
IE703/82A IE52936B1 (en) 1981-03-26 1982-03-25 Composition of matter comprising a lyophilized preparation of a penicillin derivative

Country Status (23)

Country Link
JP (1) JPS57159708A (en)
AT (1) AT395533B (en)
AU (1) AU549784B2 (en)
BE (1) BE892541A (en)
CA (1) CA1209477A (en)
CH (1) CH652306A5 (en)
DE (2) DE3208505A1 (en)
DK (1) DK157976C (en)
ES (1) ES8302455A1 (en)
FR (1) FR2502624B1 (en)
GB (1) GB2095551B (en)
GR (1) GR78386B (en)
HK (1) HK39189A (en)
HU (1) HU186489B (en)
IE (1) IE52936B1 (en)
IL (1) IL64924A (en)
IT (1) IT1147916B (en)
LU (1) LU84031A1 (en)
NL (1) NL192664C (en)
NZ (1) NZ199632A (en)
PL (1) PL130564B1 (en)
SE (1) SE453153B (en)
ZA (1) ZA82605B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6207661B1 (en) * 1999-02-22 2001-03-27 Baxter International Inc. Premixed formulation of piperacillin sodium and tazobactam sodium injection
EP1675573B2 (en) 2003-10-23 2012-06-13 Otsuka Pharmaceutical Co., Ltd. Controlled release sterile injectable aripiprazole formulation and method
ITMI20051630A1 (en) * 2005-09-02 2007-03-03 Acs Dobfar Spa INJECTABLE STERILE PHARMACEUTICAL FORMULATION CONTAINING AT LEAST TWO ACTIVE PRINCIPLES
PT2170279T (en) 2007-07-31 2018-04-06 Otsuka Pharma Co Ltd Methods for producing aripiprazole suspension and freeze-dried formulation
CN114200057A (en) * 2021-12-14 2022-03-18 坛墨质检科技股份有限公司 Preparation method of antibiotic medicine solid mixed standard substance capable of replacing standard solution

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2608507A (en) * 1949-08-20 1952-08-26 Sharp & Dohme Inc Dialkyl sulfamyl benzoic acids
CH546783A (en) * 1971-03-11 1974-03-15 Hoffmann La Roche PROCESS FOR THE PRODUCTION OF PENICILLOIC ACID DERIVATIVES.
JPS5817728B2 (en) * 1973-11-20 1983-04-09 山之内製薬株式会社 Ampicillin Sodium
IL47168A (en) * 1974-05-09 1979-07-25 Toyama Chemical Co Ltd Mono or dioxo piperazino(thio)carbonylamino derivatives ofpenicillins and cephalosporins and process for producing the same
JPS52143221A (en) * 1976-05-22 1977-11-29 Yamanouchi Pharmaceut Co Ltd Novel preparations for rectal administration
DE2623835C2 (en) * 1976-05-28 1978-03-02 C.H. Boehringer Sohn, 6507 Ingelheim Process for the manufacture of sodium amphicillin
JPS542337A (en) * 1977-06-08 1979-01-09 Toyama Chem Co Ltd Bactericidal composition for medical use
FR2403078A1 (en) * 1977-09-19 1979-04-13 Lafon Labor NEW PROCESS FOR THE PREPARATION OF PHARMACEUTICAL, COSMETIC OR DIAGNOSIS FORMS
JPS54147917A (en) * 1978-05-08 1979-11-19 Sumitomo Chem Co Ltd Ferrze-drying method
PT70225A (en) * 1978-10-03 1979-10-01 Gist Brocades Nv Process for the preparation of sodium amoxicillin preparations
DE2925009A1 (en) * 1979-06-21 1981-01-08 Basf Ag PREPARATION FOR SUBSTANCES, METHOD FOR THE PRODUCTION AND USE THEREOF

Also Published As

Publication number Publication date
FR2502624B1 (en) 1985-10-25
DE19375106I2 (en) 2006-02-16
IT1147916B (en) 1986-11-26
AU7986582A (en) 1982-09-30
ES509234A0 (en) 1982-12-16
NL192664B (en) 1997-08-01
FR2502624A1 (en) 1982-10-01
SE453153B (en) 1988-01-18
DK157976C (en) 1990-08-27
HU186489B (en) 1985-08-28
ES8302455A1 (en) 1982-12-16
NL8201251A (en) 1982-10-18
DK157976B (en) 1990-03-12
IL64924A (en) 1985-07-31
IT8248034A0 (en) 1982-03-19
PL235509A1 (en) 1982-12-20
GB2095551A (en) 1982-10-06
NZ199632A (en) 1985-07-12
DK48382A (en) 1982-09-27
DE3208505C2 (en) 1991-11-28
HK39189A (en) 1989-05-19
CH652306A5 (en) 1985-11-15
LU84031A1 (en) 1982-07-08
DE3208505A1 (en) 1982-10-21
GR78386B (en) 1984-09-26
AT395533B (en) 1993-01-25
NL192664C (en) 1997-12-02
JPS57159708A (en) 1982-10-01
CA1209477A (en) 1986-08-12
JPH0219804B2 (en) 1990-05-07
IL64924A0 (en) 1982-04-30
GB2095551B (en) 1984-10-03
ATA92982A (en) 1992-06-15
SE8200591L (en) 1982-09-27
IE52936B1 (en) 1988-04-13
AU549784B2 (en) 1986-02-13
BE892541A (en) 1982-09-20
PL130564B1 (en) 1984-08-31
ZA82605B (en) 1982-12-29

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