ES8302455A1 - Composition of matter comprising a lyophilized preparation of a penicillin derivative - Google Patents

Composition of matter comprising a lyophilized preparation of a penicillin derivative

Info

Publication number
ES8302455A1
ES8302455A1 ES509234A ES509234A ES8302455A1 ES 8302455 A1 ES8302455 A1 ES 8302455A1 ES 509234 A ES509234 A ES 509234A ES 509234 A ES509234 A ES 509234A ES 8302455 A1 ES8302455 A1 ES 8302455A1
Authority
ES
Spain
Prior art keywords
penicillin derivative
matter
composition
lyophilized
lyophilized preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES509234A
Other languages
Spanish (es)
Other versions
ES509234A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22935482&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES8302455(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of ES8302455A1 publication Critical patent/ES8302455A1/en
Publication of ES509234A0 publication Critical patent/ES509234A0/en
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Abstract

Preparation of a pharmaceutical parenteral dosage unit of a lyophilized penicillin derivative in which the penicillin derivative is dissolved in water to a concentration of 100-135 mg/ml, as compared to the standard concentration of 200 mg/ml. The solution is then filled into a container and lyophilized by known techniques. The product is a light, fluffy lyophilized product which upon reconstitution will go into solution rapidly and completely even at the high concentration of 400 mg/ml.
ES509234A 1981-03-26 1982-02-01 PROCEDURE FOR PREPARING A PHARMACEUTICAL PARENTEPAL DOSING UNIT. Granted ES509234A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24758681A 1981-03-26 1981-03-26

Publications (2)

Publication Number Publication Date
ES8302455A1 true ES8302455A1 (en) 1982-12-16
ES509234A0 ES509234A0 (en) 1982-12-16

Family

ID=22935482

Family Applications (1)

Application Number Title Priority Date Filing Date
ES509234A Granted ES509234A0 (en) 1981-03-26 1982-02-01 PROCEDURE FOR PREPARING A PHARMACEUTICAL PARENTEPAL DOSING UNIT.

Country Status (23)

Country Link
JP (1) JPS57159708A (en)
AT (1) AT395533B (en)
AU (1) AU549784B2 (en)
BE (1) BE892541A (en)
CA (1) CA1209477A (en)
CH (1) CH652306A5 (en)
DE (2) DE3208505A1 (en)
DK (1) DK157976C (en)
ES (1) ES509234A0 (en)
FR (1) FR2502624B1 (en)
GB (1) GB2095551B (en)
GR (1) GR78386B (en)
HK (1) HK39189A (en)
HU (1) HU186489B (en)
IE (1) IE52936B1 (en)
IL (1) IL64924A (en)
IT (1) IT1147916B (en)
LU (1) LU84031A1 (en)
NL (1) NL192664C (en)
NZ (1) NZ199632A (en)
PL (1) PL130564B1 (en)
SE (1) SE453153B (en)
ZA (1) ZA82605B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6207661B1 (en) 1999-02-22 2001-03-27 Baxter International Inc. Premixed formulation of piperacillin sodium and tazobactam sodium injection
PT1675573E (en) 2003-10-23 2008-12-30 Otsuka Pharma Co Ltd Controlled release sterile injectable aripiprazole formulation and method
ITMI20051630A1 (en) * 2005-09-02 2007-03-03 Acs Dobfar Spa INJECTABLE STERILE PHARMACEUTICAL FORMULATION CONTAINING AT LEAST TWO ACTIVE PRINCIPLES
RU2483711C2 (en) 2007-07-31 2013-06-10 Оцука Фармасьютикал Ко., Лтд. Methods of obtaining aripiprazole suspension and lyophilysed composition
CN114200057A (en) * 2021-12-14 2022-03-18 坛墨质检科技股份有限公司 Preparation method of antibiotic medicine solid mixed standard substance capable of replacing standard solution

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2608507A (en) * 1949-08-20 1952-08-26 Sharp & Dohme Inc Dialkyl sulfamyl benzoic acids
CH546783A (en) * 1971-03-11 1974-03-15 Hoffmann La Roche PROCESS FOR THE PRODUCTION OF PENICILLOIC ACID DERIVATIVES.
JPS5817728B2 (en) * 1973-11-20 1983-04-09 山之内製薬株式会社 Ampicillin Sodium
IL47168A (en) * 1974-05-09 1979-07-25 Toyama Chemical Co Ltd Mono or dioxo piperazino(thio)carbonylamino derivatives ofpenicillins and cephalosporins and process for producing the same
JPS52143221A (en) * 1976-05-22 1977-11-29 Yamanouchi Pharmaceut Co Ltd Novel preparations for rectal administration
DE2623835C2 (en) * 1976-05-28 1978-03-02 C.H. Boehringer Sohn, 6507 Ingelheim Process for the manufacture of sodium amphicillin
JPS542337A (en) * 1977-06-08 1979-01-09 Toyama Chem Co Ltd Bactericidal composition for medical use
FR2403078A1 (en) * 1977-09-19 1979-04-13 Lafon Labor NEW PROCESS FOR THE PREPARATION OF PHARMACEUTICAL, COSMETIC OR DIAGNOSIS FORMS
JPS54147917A (en) * 1978-05-08 1979-11-19 Sumitomo Chem Co Ltd Ferrze-drying method
PT70225A (en) * 1978-10-03 1979-10-01 Gist Brocades Nv Process for the preparation of sodium amoxicillin preparations
DE2925009A1 (en) * 1979-06-21 1981-01-08 Basf Ag PREPARATION FOR SUBSTANCES, METHOD FOR THE PRODUCTION AND USE THEREOF

Also Published As

Publication number Publication date
LU84031A1 (en) 1982-07-08
DE3208505C2 (en) 1991-11-28
GB2095551B (en) 1984-10-03
IT1147916B (en) 1986-11-26
JPS57159708A (en) 1982-10-01
CH652306A5 (en) 1985-11-15
FR2502624B1 (en) 1985-10-25
IL64924A0 (en) 1982-04-30
SE453153B (en) 1988-01-18
NZ199632A (en) 1985-07-12
IE820703L (en) 1982-09-26
FR2502624A1 (en) 1982-10-01
DK157976C (en) 1990-08-27
SE8200591L (en) 1982-09-27
CA1209477A (en) 1986-08-12
JPH0219804B2 (en) 1990-05-07
BE892541A (en) 1982-09-20
IE52936B1 (en) 1988-04-13
ES509234A0 (en) 1982-12-16
GR78386B (en) 1984-09-26
HK39189A (en) 1989-05-19
IL64924A (en) 1985-07-31
DK157976B (en) 1990-03-12
PL235509A1 (en) 1982-12-20
NL192664B (en) 1997-08-01
NL8201251A (en) 1982-10-18
ZA82605B (en) 1982-12-29
GB2095551A (en) 1982-10-06
ATA92982A (en) 1992-06-15
PL130564B1 (en) 1984-08-31
DE19375106I2 (en) 2006-02-16
HU186489B (en) 1985-08-28
AU549784B2 (en) 1986-02-13
DK48382A (en) 1982-09-27
AT395533B (en) 1993-01-25
IT8248034A0 (en) 1982-03-19
AU7986582A (en) 1982-09-30
NL192664C (en) 1997-12-02
DE3208505A1 (en) 1982-10-21

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