IE781883L - Pyrrolidine derivatives. - Google Patents

Pyrrolidine derivatives.

Info

Publication number
IE781883L
IE781883L IE781883A IE188378A IE781883L IE 781883 L IE781883 L IE 781883L IE 781883 A IE781883 A IE 781883A IE 188378 A IE188378 A IE 188378A IE 781883 L IE781883 L IE 781883L
Authority
IE
Ireland
Prior art keywords
pyrrolidine derivatives
formula
phloroglucinol
therapeutics
compounds
Prior art date
Application number
IE781883A
Other versions
IE47367B1 (en
Original Assignee
Lafon Labor
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lafon Labor filed Critical Lafon Labor
Publication of IE781883L publication Critical patent/IE781883L/en
Publication of IE47367B1 publication Critical patent/IE47367B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

New derivatives of phloroglucinol of formula <IMAGE> where R is H or CH3, and their acid addition salts are disclosed. The compounds of formula I and their non-toxic salts are useful in therapeutics as peripheral vasodilating agents. [FR2404003A1]
IE1883/78A 1977-09-26 1978-09-18 New phloroglucinol derivatives,their method of preparation and their use as pharmaceuticals IE47367B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3998277 1977-09-26

Publications (2)

Publication Number Publication Date
IE781883L true IE781883L (en) 1979-03-26
IE47367B1 IE47367B1 (en) 1984-03-07

Family

ID=10412559

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1883/78A IE47367B1 (en) 1977-09-26 1978-09-18 New phloroglucinol derivatives,their method of preparation and their use as pharmaceuticals

Country Status (14)

Country Link
JP (1) JPS5495562A (en)
AU (1) AU523963B2 (en)
BE (1) BE870717A (en)
CA (1) CA1126738A (en)
CH (1) CH633774A5 (en)
DE (1) DE2858813C2 (en)
DK (1) DK156395C (en)
ES (1) ES473689A1 (en)
FR (1) FR2404003A1 (en)
IE (1) IE47367B1 (en)
IT (1) IT1108172B (en)
LU (1) LU80277A1 (en)
NL (1) NL190720C (en)
SE (1) SE436277B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4273776A (en) 1980-01-30 1981-06-16 E. R. Squibb & Sons, Inc. Antibacterial and antifungal derivatives of 3-(1H-imidazol-1-yl)-2-propen-1-ones
FR2504136A1 (en) * 1981-04-15 1982-10-22 Lafon Labor (2,6-DIMETHOXY-4-HYDROXYPHENYL) - (3-PIPERIDINOPROPYL) -CETONE AND ITS ADDITION SALTS, THERAPEUTIC USE AND PREPARATION METHOD
ES8706598A1 (en) * 1985-04-11 1987-07-01 Nippon Kayaku Kk New derivatives of an aminoketone.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2092133B1 (en) * 1970-05-06 1974-03-22 Orsymonde
FR2134218A1 (en) * 1971-04-27 1972-12-08 Penciolelli Madeleine Phloroglucinol aminoketones - vasodilators and antispasmodics

Also Published As

Publication number Publication date
SE436277B (en) 1984-11-26
JPS5495562A (en) 1979-07-28
NL7809754A (en) 1979-03-28
DK156395B (en) 1989-08-14
IT7869202A0 (en) 1978-09-25
DK419178A (en) 1979-03-27
DE2858813C2 (en) 1993-07-01
FR2404003B1 (en) 1981-07-31
IT1108172B (en) 1985-12-02
CA1126738A (en) 1982-06-29
CH633774A5 (en) 1982-12-31
DK156395C (en) 1990-01-08
AU4019578A (en) 1980-04-03
AU523963B2 (en) 1982-08-26
SE7809916L (en) 1979-03-27
ES473689A1 (en) 1979-05-01
LU80277A1 (en) 1979-06-01
IE47367B1 (en) 1984-03-07
NL190720C (en) 1994-07-18
NL190720B (en) 1994-02-16
FR2404003A1 (en) 1979-04-20
BE870717A (en) 1979-03-26

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Legal Events

Date Code Title Description
MM4A Patent lapsed