ES473689A1 - Novel phloroglucine derivative*its manufacture and use as medicine - Google Patents

Novel phloroglucine derivative*its manufacture and use as medicine

Info

Publication number
ES473689A1
ES473689A1 ES473689A ES473689A ES473689A1 ES 473689 A1 ES473689 A1 ES 473689A1 ES 473689 A ES473689 A ES 473689A ES 473689 A ES473689 A ES 473689A ES 473689 A1 ES473689 A1 ES 473689A1
Authority
ES
Spain
Prior art keywords
phloroglucine
medicine
derivative
novel
manufacture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES473689A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cephalon France SAS
Original Assignee
Laboratoire L Lafon SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire L Lafon SA filed Critical Laboratoire L Lafon SA
Publication of ES473689A1 publication Critical patent/ES473689A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

New derivatives of phloroglucinol of formula < IMAGE > where R is H or CH3, and their acid addition salts are disclosed. The compounds of formula I and their non-toxic salts are useful in therapeutics as peripheral vasodilating agents.
ES473689A 1977-09-26 1978-09-26 Novel phloroglucine derivative*its manufacture and use as medicine Expired ES473689A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3998277 1977-09-26

Publications (1)

Publication Number Publication Date
ES473689A1 true ES473689A1 (en) 1979-05-01

Family

ID=10412559

Family Applications (1)

Application Number Title Priority Date Filing Date
ES473689A Expired ES473689A1 (en) 1977-09-26 1978-09-26 Novel phloroglucine derivative*its manufacture and use as medicine

Country Status (14)

Country Link
JP (1) JPS5495562A (en)
AU (1) AU523963B2 (en)
BE (1) BE870717A (en)
CA (1) CA1126738A (en)
CH (1) CH633774A5 (en)
DE (1) DE2858813C2 (en)
DK (1) DK156395C (en)
ES (1) ES473689A1 (en)
FR (1) FR2404003A1 (en)
IE (1) IE47367B1 (en)
IT (1) IT1108172B (en)
LU (1) LU80277A1 (en)
NL (1) NL190720C (en)
SE (1) SE436277B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4273776A (en) 1980-01-30 1981-06-16 E. R. Squibb & Sons, Inc. Antibacterial and antifungal derivatives of 3-(1H-imidazol-1-yl)-2-propen-1-ones
FR2504136A1 (en) * 1981-04-15 1982-10-22 Lafon Labor (2,6-DIMETHOXY-4-HYDROXYPHENYL) - (3-PIPERIDINOPROPYL) -CETONE AND ITS ADDITION SALTS, THERAPEUTIC USE AND PREPARATION METHOD
DE3688917T2 (en) * 1985-04-11 1994-02-10 Nippon Kayaku Kk Derivatives of an amino ketone.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2092133B1 (en) * 1970-05-06 1974-03-22 Orsymonde
FR2134218A1 (en) * 1971-04-27 1972-12-08 Penciolelli Madeleine Phloroglucinol aminoketones - vasodilators and antispasmodics

Also Published As

Publication number Publication date
SE7809916L (en) 1979-03-27
SE436277B (en) 1984-11-26
CH633774A5 (en) 1982-12-31
DK156395B (en) 1989-08-14
LU80277A1 (en) 1979-06-01
IE47367B1 (en) 1984-03-07
NL7809754A (en) 1979-03-28
IE781883L (en) 1979-03-26
DK156395C (en) 1990-01-08
DK419178A (en) 1979-03-27
AU4019578A (en) 1980-04-03
NL190720C (en) 1994-07-18
FR2404003B1 (en) 1981-07-31
IT1108172B (en) 1985-12-02
IT7869202A0 (en) 1978-09-25
AU523963B2 (en) 1982-08-26
FR2404003A1 (en) 1979-04-20
JPS5495562A (en) 1979-07-28
CA1126738A (en) 1982-06-29
BE870717A (en) 1979-03-26
DE2858813C2 (en) 1993-07-01
NL190720B (en) 1994-02-16

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000301